Kmt5c (lysine methyltransferase 5C) - Rat Genome Database

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Gene: Kmt5c (lysine methyltransferase 5C) Rattus norvegicus
Analyze
Symbol: Kmt5c
Name: lysine methyltransferase 5C
RGD ID: 1305226
Description: Predicted to enable several functions, including S-adenosyl-L-methionine binding activity; histone H4K20 methyltransferase activity; and histone binding activity. Predicted to be involved in DNA repair; positive regulation of double-strand break repair via nonhomologous end joining; and positive regulation of isotype switching. Predicted to be located in condensed chromosome, centromeric region and pericentric heterochromatin. Predicted to be active in nucleus. Biomarker of liver benign neoplasm. Orthologous to human KMT5C (lysine methyltransferase 5C); PARTICIPATES IN histone modification pathway; lysine degradation pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: [histone H4]-lysine20 N-methyltransferase KMT5B; [histone H4]-N-methyl-L-lysine20 N-methyltransferase KMT5B; histone-lysine N-methyltransferase KMT5C; histone-lysine N-methyltransferase SUV420H2; LOC308345; lysine (K)-specific methyltransferase 5C; lysine-specific methyltransferase 5C; su(var)4-20 homolog 2; suppressor of variegation 4-20 homolog 2; suppressor of variegation 4-20 homolog 2 (Drosophila); suv4-20h2; Suv420h2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8178,128,325 - 78,135,931 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl178,128,325 - 78,135,931 (-)EnsemblGRCr8
mRatBN7.2169,099,531 - 69,107,145 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl169,099,539 - 69,107,145 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx174,444,576 - 74,452,182 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0183,008,879 - 83,016,485 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0176,157,538 - 76,165,177 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0172,666,662 - 72,674,271 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl172,666,665 - 72,674,271 (-)Ensemblrn6Rnor6.0
Rnor_5.0175,861,337 - 75,868,946 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4167,815,981 - 67,823,611 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera168,017,407 - 68,024,973 (+)NCBICelera
RGSC_v3.1167,894,088 - 67,899,997 (-)NCBI
Cytogenetic Map1q12NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Histone lysine methylation dynamics: establishment, regulation, and biological impact. Black JC, etal., Mol Cell. 2012 Nov 30;48(4):491-507. doi: 10.1016/j.molcel.2012.11.006.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. Histone H3 lysine 9 and H4 lysine 20 trimethylation and the expression of Suv4-20h2 and Suv-39h1 histone methyltransferases in hepatocarcinogenesis induced by methyl deficiency in rats. Pogribny IP, etal., Carcinogenesis. 2006 Jun;27(6):1180-6. Epub 2006 Feb 23.
6. GOA pipeline RGD automated data pipeline
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Comprehensive gene review and curation RGD comprehensive gene curation
9. Epigenetic changes in mitochondrial superoxide dismutase in the retina and the development of diabetic retinopathy. Zhong Q and Kowluru RA, Diabetes. 2011 Apr;60(4):1304-13. doi: 10.2337/db10-0133. Epub 2011 Feb 25.
Additional References at PubMed
PMID:15145825   PMID:17182829   PMID:19486527   PMID:24049080   PMID:24396869   PMID:25335925   PMID:28114273  


Genomics

Comparative Map Data
Kmt5c
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8178,128,325 - 78,135,931 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl178,128,325 - 78,135,931 (-)EnsemblGRCr8
mRatBN7.2169,099,531 - 69,107,145 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl169,099,539 - 69,107,145 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx174,444,576 - 74,452,182 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0183,008,879 - 83,016,485 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0176,157,538 - 76,165,177 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0172,666,662 - 72,674,271 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl172,666,665 - 72,674,271 (-)Ensemblrn6Rnor6.0
Rnor_5.0175,861,337 - 75,868,946 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4167,815,981 - 67,823,611 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera168,017,407 - 68,024,973 (+)NCBICelera
RGSC_v3.1167,894,088 - 67,899,997 (-)NCBI
Cytogenetic Map1q12NCBI
KMT5C
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381955,339,876 - 55,348,121 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1955,339,367 - 55,348,121 (+)Ensemblhg38GRCh38
GRCh371955,851,244 - 55,859,489 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361960,543,076 - 60,551,301 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341960,543,075 - 60,551,300NCBI
Celera1952,892,173 - 52,900,453 (+)NCBICelera
Cytogenetic Map19q13.42NCBI
HuRef1952,173,507 - 52,181,789 (+)NCBIHuRef
CHM1_11955,845,041 - 55,853,309 (+)NCBICHM1_1
T2T-CHM13v2.01958,435,370 - 58,443,627 (+)NCBIT2T-CHM13v2.0
Kmt5c
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3974,743,091 - 4,750,513 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl74,743,114 - 4,750,513 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm3874,740,092 - 4,747,514 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl74,740,115 - 4,747,514 (+)Ensemblmm10GRCm38
MGSCv3774,691,729 - 4,699,116 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv3674,343,275 - 4,350,574 (+)NCBIMGSCv36mm8
Celera74,470,199 - 4,477,587 (+)NCBICelera
Cytogenetic Map7A1NCBI
cM Map72.74NCBI
Kmt5c
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955567894,608 - 900,578 (-)Ensembl
ChiLan1.0NW_004955567895,334 - 901,240 (-)NCBIChiLan1.0ChiLan1.0
KMT5C
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22061,476,795 - 61,485,754 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11963,205,884 - 63,214,838 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01952,381,963 - 52,390,507 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11961,073,185 - 61,079,389 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1961,073,396 - 61,078,717 (+)EnsemblpanPan2panpan1.1
KMT5C
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11102,334,687 - 102,342,090 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1102,333,543 - 102,342,118 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1102,391,254 - 102,398,667 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01102,987,756 - 102,995,170 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1102,986,612 - 102,995,188 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11102,625,010 - 102,632,419 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01102,337,091 - 102,344,516 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01103,100,299 - 103,107,712 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Kmt5c
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244093491,956,266 - 1,963,342 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936886595,782 - 604,286 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936886596,949 - 602,959 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KMT5C
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl659,517,098 - 59,524,550 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1659,517,058 - 59,524,551 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
KMT5C
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1647,942,100 - 47,950,364 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl647,944,197 - 47,949,693 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666045576,523 - 584,848 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Kmt5c
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248321,945,193 - 1,951,247 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248321,945,194 - 1,951,016 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Kmt5c
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v12177,315,616 - 177,323,379 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Kmt5c
253 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:84
Count of miRNA genes:73
Interacting mature miRNAs:79
Transcripts:ENSRNOT00000023744
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331732Srn4Serum renin concentration QTL 44.467renin activity (VT:0005581)plasma renin activity level (CMO:0000116)14345783787558729Rat
1578649Bmd8Bone mineral density QTL 84.9femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)151940904101229020Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)139728272132889942Rat
4889929Bss87Bone structure and strength QTL 876.7tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)14630261591302615Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)151941022208479811Rat
1331792Rf29Renal function QTL 294.589urine potassium amount (VT:0010539)urine potassium level (CMO:0000128)14345783787558729Rat
2313062Bmd73Bone mineral density QTL 733.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)14630261591302615Rat
8552900Pigfal1Plasma insulin-like growth factor 1 level QTL 17.4blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)14350995288509952Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)151940904168768703Rat
1354643Foco2Food consumption QTL 27.170.0001eating behavior trait (VT:0001431)food intake rate (CMO:0000427)14212296887122968Rat
2313065Bss67Bone structure and strength QTL 673.10.0001tibia area (VT:1000281)tibia total energy absorbed before break (CMO:0001736)14630261591302615Rat
2313069Bss68Bone structure and strength QTL 682.90.0001tibia size trait (VT:0100001)tibia total energy absorbed before break (CMO:0001736)14630261591302615Rat
631495Bp96Blood pressure QTL 964.52arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)166404680111404680Rat
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134184556172281316Rat
2313075Bss66Bone structure and strength QTL 663.40.0001tibia length (VT:0004357)tibia length (CMO:0000450)14630261591302615Rat
2298545Neuinf8Neuroinflammation QTL 84.6nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)166009857160501508Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134565911208798288Rat
1331778Rf28Renal function QTL 284.66urine potassium amount (VT:0010539)urine potassium excretion rate (CMO:0000761)14345783787558729Rat
2313077Bss69Bone structure and strength QTL 693.50.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)14630261591302615Rat
1302788Scl19Serum cholesterol QTL 194.60.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)166400974132889942Rat
2313402Anxrr24Anxiety related response QTL 24aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)151511344153680016Rat
1331785Rf27Renal function QTL 274.643urine sodium amount (VT:0006274)urine sodium level (CMO:0000129)13070837587558729Rat
61342Bp27Blood pressure QTL 273.40.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16540563796805205Rat
1300172Bp172Blood pressure QTL 1723.56arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)13456572679565726Rat
4889962Bss94Bone structure and strength QTL 943.8tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)15190920691302615Rat
6903308Scl36Serum cholesterol QTL 3620.0125blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)158769992103769992Rat
2313092Bmd72Bone mineral density QTL 722.50.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)14630261591302615Rat
2300164Bmd44Bone mineral density QTL 445.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)166077886111077886Rat
2313097Bss70Bone structure and strength QTL 703.50.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)14630261591302615Rat
9589820Insglur3Insulin/glucose ratio QTL 310.750.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)14350995288509952Rat
152025249Scl82Serum cholesterol level QTL 824.77blood cholesterol amount (VT:0000180)152891222109116986Rat
1354599Bw29Body weight QTL 293.460.001body mass (VT:0001259)body weight (CMO:0000012)14212296887122968Rat
4889919Bss86Bone structure and strength QTL 864.1tibia area (VT:1000281)tibia midshaft total cross-sectional area (CMO:0001715)14630261591302615Rat
8552948Pigfal11Plasma insulin-like growth factor 1 level QTL 114.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)14350995288509952Rat

Markers in Region
BE107946  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2169,099,441 - 69,099,656 (+)MAPPERmRatBN7.2
Rnor_6.0172,666,568 - 72,666,782NCBIRnor6.0
Rnor_5.0175,868,826 - 75,869,040UniSTSRnor5.0
RGSC_v3.4167,815,884 - 67,816,098UniSTSRGSC3.4
Celera168,024,856 - 68,025,070UniSTS
Cytogenetic Map1q12UniSTS
BF396701  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2169,103,071 - 69,103,271 (+)MAPPERmRatBN7.2
Rnor_6.0172,670,198 - 72,670,397NCBIRnor6.0
Rnor_5.0175,865,211 - 75,865,410UniSTSRnor5.0
RGSC_v3.4167,819,514 - 67,819,713UniSTSRGSC3.4
Celera168,021,244 - 68,021,443UniSTS
Cytogenetic Map1q12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
23 12 81 206 91 90 59 110 59 6 434 232 20 185 112 115 31 33 33

Sequence


Ensembl Acc Id: ENSRNOT00000023744   ⟹   ENSRNOP00000023744
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl178,128,325 - 78,135,931 (-)Ensembl
mRatBN7.2 Ensembl169,099,539 - 69,107,145 (-)Ensembl
Rnor_6.0 Ensembl172,666,665 - 72,674,271 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000129505   ⟹   ENSRNOP00000111531
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl178,128,325 - 78,135,931 (-)Ensembl
RefSeq Acc Id: NM_001107475   ⟹   NP_001100945
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8178,128,325 - 78,135,931 (-)NCBI
mRatBN7.2169,099,539 - 69,107,145 (-)NCBI
Rnor_6.0172,666,665 - 72,674,271 (-)NCBI
Rnor_5.0175,861,337 - 75,868,946 (+)NCBI
RGSC_v3.4167,815,981 - 67,823,611 (-)RGD
Celera168,017,407 - 68,024,973 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001100945 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL75851 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000023744
  ENSRNOP00000023744.5
GenBank Protein P0C2N6 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001100945   ⟸   NM_001107475
- UniProtKB: P0C2N6 (UniProtKB/Swiss-Prot),   A6KNN2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000023744   ⟸   ENSRNOT00000023744
Ensembl Acc Id: ENSRNOP00000111531   ⟸   ENSRNOT00000129505
Protein Domains
SET

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P0C2N6-F1-model_v2 AlphaFold P0C2N6 1-470 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13689699
Promoter ID:EPDNEW_R224
Type:single initiation site
Name:Kmt5c_1
Description:lysine methyltransferase 5C
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0172,674,227 - 72,674,287EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305226 AgrOrtholog
BioCyc Gene G2FUF-60856 BioCyc
Ensembl Genes ENSRNOG00000017508 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000023744 ENTREZGENE
  ENSRNOT00000023744.6 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.10.1700 UniProtKB/Swiss-Prot
  2.170.270.10 UniProtKB/Swiss-Prot
InterPro Hist-Lys_N-MTase_N UniProtKB/Swiss-Prot
  Hist-Lys_N-MTase_Suvar4-20 UniProtKB/Swiss-Prot
  KMT5B/KMT5C/SET9 UniProtKB/Swiss-Prot
  KMT5C_SET UniProtKB/Swiss-Prot
  SET_dom UniProtKB/Swiss-Prot
  SET_dom_sf UniProtKB/Swiss-Prot
KEGG Report rno:308345 UniProtKB/Swiss-Prot
NCBI Gene 308345 ENTREZGENE
PANTHER HISTONE-LYSINE N-METHYLTRANSFERASE KMT5C UniProtKB/Swiss-Prot
  PTHR12977 UniProtKB/Swiss-Prot
Pfam SET UniProtKB/Swiss-Prot
PhenoGen Kmt5c PhenoGen
PROSITE SAM_MT43_SUVAR420_2 UniProtKB/Swiss-Prot
  SET UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000017508 RatGTEx
SMART SET UniProtKB/Swiss-Prot
Superfamily-SCOP SSF82199 UniProtKB/Swiss-Prot
UniProt A0ABK0LYL9_RAT UniProtKB/TrEMBL
  A6KNN2 ENTREZGENE, UniProtKB/TrEMBL
  KMT5C_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-17 Kmt5c  lysine methyltransferase 5C  Kmt5c  lysine (K)-specific methyltransferase 5C  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2015-11-12 Kmt5c  lysine (K)-specific methyltransferase 5C  Suv420h2  suppressor of variegation 4-20 homolog 2 (Drosophila)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Suv420h2  suppressor of variegation 4-20 homolog 2 (Drosophila)   Suv420h2_predicted  suppressor of variegation 4-20 homolog 2 (Drosophila) (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Suv420h2_predicted  suppressor of variegation 4-20 homolog 2 (Drosophila) (predicted)      Symbol and Name status set to approved 70820 APPROVED