Slc66a2 (solute carrier family 66 member 2) - Rat Genome Database

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Gene: Slc66a2 (solute carrier family 66 member 2) Rattus norvegicus
Analyze
Symbol: Slc66a2
Name: solute carrier family 66 member 2
RGD ID: 1305223
Description: Predicted to be involved in phospholipid translocation and retrograde transport, endosome to Golgi. Predicted to be located in cytosol and membrane. Predicted to be active in endosome and trans-Golgi network. Orthologous to human SLC66A2 (solute carrier family 66 member 2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC361352; PQ loop repeat containing 1; PQ-loop repeat-containing protein 1; Pqlc1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81875,976,000 - 76,014,651 (+)NCBIGRCr8
mRatBN7.21873,702,472 - 73,739,678 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1873,702,564 - 73,739,676 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1875,805,106 - 75,842,255 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01876,474,446 - 76,511,598 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01874,319,964 - 74,357,311 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01876,768,466 - 76,805,773 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1876,770,012 - 76,805,766 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01872,002,639 - 72,040,511 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41877,151,194 - 77,187,603 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11877,224,466 - 77,260,874 (+)NCBI
Celera1872,366,086 - 72,401,733 (+)NCBICelera
Cytogenetic Map18q12.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytosol  (IEA)
endosome  (IBA,IEA)
membrane  (IEA)
trans-Golgi network  (IBA,IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:15489334  


Genomics

Comparative Map Data
Slc66a2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81875,976,000 - 76,014,651 (+)NCBIGRCr8
mRatBN7.21873,702,472 - 73,739,678 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1873,702,564 - 73,739,676 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1875,805,106 - 75,842,255 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01876,474,446 - 76,511,598 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01874,319,964 - 74,357,311 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01876,768,466 - 76,805,773 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1876,770,012 - 76,805,766 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01872,002,639 - 72,040,511 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41877,151,194 - 77,187,603 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11877,224,466 - 77,260,874 (+)NCBI
Celera1872,366,086 - 72,401,733 (+)NCBICelera
Cytogenetic Map18q12.3NCBI
SLC66A2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381879,902,420 - 79,951,653 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1879,902,420 - 79,951,657 (-)EnsemblGRCh38hg38GRCh38
GRCh371877,662,420 - 77,711,653 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361875,763,475 - 75,812,605 (-)NCBINCBI36Build 36hg18NCBI36
Build 341875,763,475 - 75,812,605NCBI
Celera1874,434,080 - 74,482,339 (-)NCBICelera
Cytogenetic Map18q23NCBI
HuRef1874,283,976 - 74,332,865 (-)NCBIHuRef
CHM1_11877,656,671 - 77,706,865 (-)NCBICHM1_1
T2T-CHM13v2.01880,178,398 - 80,227,221 (-)NCBIT2T-CHM13v2.0
Slc66a2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391880,298,458 - 80,335,940 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1880,296,507 - 80,335,940 (+)EnsemblGRCm39 Ensembl
GRCm381880,255,241 - 80,292,724 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1880,253,292 - 80,292,725 (+)EnsemblGRCm38mm10GRCm38
MGSCv371880,451,984 - 80,489,463 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361880,418,366 - 80,454,773 (+)NCBIMGSCv36mm8
Celera1881,375,701 - 81,413,017 (+)NCBICelera
Cytogenetic Map18E3NCBI
cM Map1853.37NCBI
Slc66a2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540263,035,932 - 63,073,980 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540263,035,932 - 63,073,981 (-)NCBIChiLan1.0ChiLan1.0
SLC66A2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21797,540,490 - 97,588,056 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11883,233,111 - 83,280,663 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01873,549,273 - 73,596,658 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11876,869,584 - 76,915,357 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1876,869,584 - 76,915,363 (-)Ensemblpanpan1.1panPan2
SLC66A2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11758,456 - 801,227 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1757,856 - 802,373 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha11,762,104 - 1,807,174 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01557,987 - 603,282 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.11610,906 - 656,174 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01556,341 - 601,630 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01727,548 - 772,828 (+)NCBIUU_Cfam_GSD_1.0
Slc66a2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494414,944,399 - 14,971,300 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936616265,850 - 292,586 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936616265,609 - 292,430 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC66A2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6127,894,111 - 127,952,225 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16127,894,111 - 127,952,268 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21310,240,990 - 310,300,141 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SLC66A2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.118311,594 - 354,877 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl18312,237 - 353,058 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606025,963,996 - 26,006,244 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Slc66a2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624806439,613 - 479,191 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624806440,001 - 479,191 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Slc66a2
265 total Variants

QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1578661Bss20Bone structure and strength QTL 203.7femur morphology trait (VT:0000559)femoral neck cross-sectional area (CMO:0001697)181179151883218561Rat
1578667Bss21Bone structure and strength QTL 213.5femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)181179151883218561Rat
1600373Mamtr6Mammary tumor resistance QTL 6mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)181927890183218561Rat
1331741Bp232Blood pressure QTL 2323.59112arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)182137289383213037Rat
1331733Bp233Blood pressure QTL 2333.97196arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182479697779788953Rat
2293704Bss35Bone structure and strength QTL 354.590.0002femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)182896485373964853Rat
2300157Bmd66Bone mineral density QTL 6613.10.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)182896485373964853Rat
2300177Bmd65Bone mineral density QTL 6519.70.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)182896485373964853Rat
9589816Gluco68Glucose level QTL 687.250.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)182979296574792965Rat
8694378Bw157Body weight QTL 1573.590.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)182979296574792965Rat
9590318Scort22Serum corticosterone level QTL 227.640.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)182979296574792965Rat
1331754Bp230Blood pressure QTL 2304.61609arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182979296574792965Rat
738005Anxrr11Anxiety related response QTL 113.4exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)183003981375039813Rat
2303120Mamtr8Mammary tumor resistance QTL 80.001mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)183135940883218561Rat
631274Sprol1Serum protein level QTL 15.3blood total protein amount (VT:0005567)serum total protein level (CMO:0000661)183139332077209694Rat
631518Bw11Body weight QTL 112.8body mass (VT:0001259)body weight (CMO:0000012)183587072380870723Rat
61367Iddm4Insulin dependent diabetes mellitus QTL 42.330.0074blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)183819245583192455Rat
1598826Anxrr20Anxiety related response QTL 203.04body movement coordination trait (VT:0005424)number of rearing movements in an experimental apparatus (CMO:0001752)184143297183828827Rat
6893683Bw110Body weight QTL 1102.70.002body mass (VT:0001259)body weight (CMO:0000012)184334502283828827Rat
8694366Abfw8Abdominal fat weight QTL 86.380.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)184664067583828827Rat
8694432Bw165Body weight QTL 1653.810.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)184664067583828827Rat
9589041Epfw12Epididymal fat weight QTL 1217.080.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)184664067583828827Rat
2303571Bw92Body weight QTL 923body mass (VT:0001259)body weight (CMO:0000012)184852004483828827Rat
2303584Gluco55Glucose level QTL 552blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)184852004483828827Rat
738008Hcar14Hepatocarcinoma resistance QTL 144.3liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion number (CMO:0001462)185146473383218561Rat
1359020Ppulsi2Prepulse inhibition QTL 22.71prepulse inhibition trait (VT:0003088)acoustic startle response measurement (CMO:0001519)185229287573997283Rat
12880368Bw187Body weight QTL 1870.045body mass (VT:0001259)body weight (CMO:0000012)185253976376104388Rat
12904067Cm122Cardiac mass QTL 1220.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)185253976376104388Rat
12904069Cm123Cardiac mass QTL 1230.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)185253976376104388Rat
12904070Cm124Cardiac mass QTL 1240.01heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)185253976376104388Rat
12904071Am18Aortic mass QTL 180.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)185253976376104388Rat
12904073Kidm71Kidney mass QTL 710.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)185253976376104388Rat
2301417Bp319Blood pressure QTL 3190.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)185253976376104388Rat
1298072Cia26Collagen induced arthritis QTL 263.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)185470976983828827Rat
724542Kidm2Kidney mass QTL 22.6kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)185917211583828827Rat
2301969Bp324Blood pressure QTL 3244.05arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)185971241776477814Rat
70185BpQTLcluster15Blood pressure QTL cluster 154.61arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)185971241776477814Rat
70185BpQTLcluster15Blood pressure QTL cluster 154.61arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)185971241776477814Rat
70185BpQTLcluster15Blood pressure QTL cluster 154.61arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)185971241776477814Rat
70185BpQTLcluster15Blood pressure QTL cluster 154.61arterial blood pressure trait (VT:2000000)absolute change in systolic blood pressure (CMO:0000607)185971241776477814Rat
6903353Bp353Blood pressure QTL 3532.8arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)185979647883828827Rat
6903356Bp354Blood pressure QTL 3544.6arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)185979647883828827Rat
61384Bp48Blood pressure QTL 4819.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)186062231177209844Rat
631675Iddm15Insulin dependent diabetes mellitus QTL 15urine glucose amount (VT:0001758)percentage of study population developing diabetes mellitus during a period of time (CMO:0001114)186062231177209844Rat

Markers in Region
RH126471  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21873,739,359 - 73,739,601 (+)MAPPERmRatBN7.2
Rnor_6.01876,805,455 - 76,805,696NCBIRnor6.0
Rnor_5.01872,002,716 - 72,002,957UniSTSRnor5.0
RGSC_v3.41877,187,285 - 77,187,526UniSTSRGSC3.4
Celera1872,401,415 - 72,401,656UniSTS
Cytogenetic Map18q12.3UniSTS
BE097236  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21873,722,686 - 73,722,848 (+)MAPPERmRatBN7.2
Rnor_6.01876,788,677 - 76,788,838NCBIRnor6.0
Rnor_5.01872,019,481 - 72,019,642UniSTSRnor5.0
RGSC_v3.41877,169,904 - 77,170,065UniSTSRGSC3.4
Celera1872,384,790 - 72,384,951UniSTS
RH 3.4 Map18787.0UniSTS
Cytogenetic Map18q12.3UniSTS
BE115218  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21873,719,901 - 73,720,120 (+)MAPPERmRatBN7.2
Rnor_6.01876,785,893 - 76,786,111NCBIRnor6.0
Rnor_5.01872,022,208 - 72,022,426UniSTSRnor5.0
RGSC_v3.41877,167,120 - 77,167,338UniSTSRGSC3.4
Celera1872,382,006 - 72,382,224UniSTS
RH 3.4 Map18785.0UniSTS
Cytogenetic Map18q12.3UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 36 57 41 19 41 8 11 74 35 35 11 8
Low 7 6
Below cutoff

Sequence


RefSeq Acc Id: ENSRNOT00000089389   ⟹   ENSRNOP00000074262
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1873,703,473 - 73,739,676 (+)Ensembl
Rnor_6.0 Ensembl1876,770,012 - 76,805,766 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000112225   ⟹   ENSRNOP00000093969
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1873,702,564 - 73,719,395 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000114669   ⟹   ENSRNOP00000086993
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1873,703,538 - 73,739,671 (+)Ensembl
RefSeq Acc Id: NM_001398665   ⟹   NP_001385594
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81875,978,459 - 76,014,651 (+)NCBI
mRatBN7.21873,703,480 - 73,739,678 (+)NCBI
RefSeq Acc Id: NM_001398666   ⟹   NP_001385595
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81875,977,458 - 76,014,651 (+)NCBI
mRatBN7.21873,702,479 - 73,739,678 (+)NCBI
RefSeq Acc Id: XM_006254952   ⟹   XP_006255014
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81875,976,000 - 76,014,651 (+)NCBI
mRatBN7.21873,703,379 - 73,739,678 (+)NCBI
Rnor_6.01876,769,292 - 76,805,773 (+)NCBI
Rnor_5.01872,002,639 - 72,040,511 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006254953   ⟹   XP_006255015
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81875,977,433 - 76,014,651 (+)NCBI
mRatBN7.21873,702,472 - 73,739,678 (+)NCBI
Rnor_6.01876,768,466 - 76,805,773 (+)NCBI
Rnor_5.01872,002,639 - 72,040,511 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017601004   ⟹   XP_017456493
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81875,977,958 - 76,014,651 (+)NCBI
mRatBN7.21873,703,204 - 73,739,678 (+)NCBI
Rnor_6.01876,768,820 - 76,805,773 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063277484   ⟹   XP_063133554
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81875,977,918 - 76,014,651 (+)NCBI
RefSeq Acc Id: XP_006255015   ⟸   XM_006254953
- Peptide Label: isoform X1
- UniProtKB: Q5M880 (UniProtKB/Swiss-Prot),   A6K5H2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006255014   ⟸   XM_006254952
- Peptide Label: isoform X1
- UniProtKB: Q5M880 (UniProtKB/Swiss-Prot),   A6K5H2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017456493   ⟸   XM_017601004
- Peptide Label: isoform X1
- UniProtKB: Q5M880 (UniProtKB/Swiss-Prot),   A6K5H2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000074262   ⟸   ENSRNOT00000089389
RefSeq Acc Id: ENSRNOP00000086993   ⟸   ENSRNOT00000114669
RefSeq Acc Id: ENSRNOP00000093969   ⟸   ENSRNOT00000112225
RefSeq Acc Id: NP_001385595   ⟸   NM_001398666
- UniProtKB: A0A8L2UR94 (UniProtKB/TrEMBL),   A6K5H3 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001385594   ⟸   NM_001398665
- UniProtKB: A0A8L2UR94 (UniProtKB/TrEMBL),   A6K5H3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063133554   ⟸   XM_063277484
- Peptide Label: isoform X2
Protein Domains
PQ-loop

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5M880-F1-model_v2 AlphaFold Q5M880 1-271 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13700889
Promoter ID:EPDNEW_R11412
Type:single initiation site
Name:Pqlc1_1
Description:PQ loop repeat containing 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01876,769,999 - 76,770,059EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305223 AgrOrtholog
BioCyc Gene G2FUF-6859 BioCyc
Ensembl Genes ENSRNOG00000059215 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOG00055013900 UniProtKB/Swiss-Prot
  ENSRNOG00060015580 UniProtKB/Swiss-Prot
  ENSRNOG00065002822 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000089389 ENTREZGENE
  ENSRNOT00000089389.2 UniProtKB/TrEMBL
  ENSRNOT00000112225.1 UniProtKB/TrEMBL
  ENSRNOT00000114669.1 UniProtKB/Swiss-Prot
  ENSRNOT00055023904 UniProtKB/Swiss-Prot
  ENSRNOT00060026685 UniProtKB/Swiss-Prot
  ENSRNOT00065003878 UniProtKB/Swiss-Prot
Gene3D-CATH 1.20.1280.290 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7121966 IMAGE-MGC_LOAD
  IMAGE:7369419 IMAGE-MGC_LOAD
InterPro PQ-loop_rpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:361352 UniProtKB/Swiss-Prot
MGC_CLONE MGC:108854 IMAGE-MGC_LOAD
  MGC:94026 IMAGE-MGC_LOAD
NCBI Gene 361352 ENTREZGENE
PANTHER PQ-LOOP REPEAT-CONTAINING PROTEIN 1-LIKE PROTEIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SOLUTE CARRIER FAMILY 66 MEMBER 2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam PQ-loop UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Slc66a2 PhenoGen
RatGTEx ENSRNOG00000059215 RatGTEx
  ENSRNOG00055013900 RatGTEx
  ENSRNOG00060015580 RatGTEx
  ENSRNOG00065002822 RatGTEx
SMART CTNS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I6AJV0_RAT UniProtKB/TrEMBL
  A0A8L2UR94 ENTREZGENE, UniProtKB/TrEMBL
  A6K5H2 ENTREZGENE, UniProtKB/TrEMBL
  A6K5H3 ENTREZGENE, UniProtKB/TrEMBL
  PQLC1_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-08-09 Slc66a2  solute carrier family 66 member 2  Pqlc1  PQ loop repeat containing 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Pqlc1  PQ loop repeat containing 1  Pqlc1_predicted  PQ loop repeat containing 1 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Pqlc1_predicted  PQ loop repeat containing 1 (predicted)      Symbol and Name status set to approved 70820 APPROVED