Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Als2cl | Rat | 1,2-dichloroethane | increases expression | ISO | Als2cl (Mus musculus) | 6480464 | ethylene dichloride results in increased expression of ALS2CL mRNA | CTD | PMID:28189721|PMID:28960355 | Als2cl | Rat | 1,2-dimethylhydrazine | affects expression | ISO | Als2cl (Mus musculus) | 6480464 | 1,2-Dimethylhydrazine affects the expression of ALS2CL mRNA | CTD | PMID:22206623 | Als2cl | Rat | 17beta-estradiol | increases expression | ISO | Als2cl (Mus musculus) | 6480464 | Estradiol results in increased expression of ALS2CL mRNA | CTD | PMID:39298647 | Als2cl | Rat | 17beta-estradiol | increases expression | ISO | ALS2CL (Homo sapiens) | 6480464 | Estradiol results in increased expression of ALS2CL mRNA | CTD | PMID:31614463 | Als2cl | Rat | 2,2',4,4'-Tetrabromodiphenyl ether | increases expression | EXP | | 6480464 | 2,2',4,4'-tetrabromodiphenyl ether results in increased expression of ALS2CL mRNA | CTD | PMID:27291303 | Als2cl | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | ALS2CL (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of ALS2CL mRNA | CTD | PMID:22903824 | Als2cl | Rat | 2-hydroxypropanoic acid | increases expression | ISO | ALS2CL (Homo sapiens) | 6480464 | Lactic Acid results in increased expression of ALS2CL mRNA | CTD | PMID:30851411 | Als2cl | Rat | 2-palmitoylglycerol | increases expression | ISO | ALS2CL (Homo sapiens) | 6480464 | 2-palmitoylglycerol results in increased expression of ALS2CL mRNA | CTD | PMID:37199045 | Als2cl | Rat | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | ALS2CL (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] more ... | CTD | PMID:28628672 | Als2cl | Rat | 4,4'-sulfonyldiphenol | multiple interactions | ISO | ALS2CL (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] more ... | CTD | PMID:28628672 | Als2cl | Rat | 4,4'-sulfonyldiphenol | affects expression | ISO | Als2cl (Mus musculus) | 6480464 | bisphenol S affects the expression of ALS2CL mRNA | CTD | PMID:39298647 | Als2cl | Rat | 4,4'-sulfonyldiphenol | increases expression | ISO | Als2cl (Mus musculus) | 6480464 | bisphenol S results in increased expression of ALS2CL mRNA | CTD | PMID:30951980 | Als2cl | Rat | actinomycin D | increases expression | ISO | ALS2CL (Homo sapiens) | 6480464 | Dactinomycin results in increased expression of ALS2CL mRNA | CTD | PMID:38460933 | Als2cl | Rat | actinomycin D | multiple interactions | ISO | ALS2CL (Homo sapiens) | 6480464 | [Dactinomycin co-treated with nutlin 3] results in increased expression of ALS2CL mRNA | CTD | PMID:38460933 | Als2cl | Rat | adefovir pivoxil | increases expression | ISO | ALS2CL (Homo sapiens) | 6480464 | adefovir dipivoxil results in increased expression of ALS2CL mRNA | CTD | PMID:25596134 | Als2cl | Rat | aflatoxin B1 | increases expression | ISO | Als2cl (Mus musculus) | 6480464 | Aflatoxin B1 results in increased expression of ALS2CL mRNA | CTD | PMID:19770486 | Als2cl | Rat | arsenous acid | increases expression | ISO | Als2cl (Mus musculus) | 6480464 | Arsenic Trioxide results in increased expression of ALS2CL mRNA | CTD | PMID:39716349 | Als2cl | Rat | benzo[a]pyrene | affects methylation | ISO | ALS2CL (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of ALS2CL promoter | CTD | PMID:27901495 | Als2cl | Rat | benzo[a]pyrene | decreases methylation | ISO | ALS2CL (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of ALS2CL 5' UTR | CTD | PMID:27901495 | Als2cl | Rat | beta-lapachone | decreases expression | ISO | ALS2CL (Homo sapiens) | 6480464 | beta-lapachone results in decreased expression of ALS2CL mRNA | CTD | PMID:38218311 | Als2cl | Rat | beta-lapachone | increases expression | ISO | ALS2CL (Homo sapiens) | 6480464 | beta-lapachone results in increased expression of ALS2CL mRNA | CTD | PMID:38218311 | Als2cl | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of ALS2CL mRNA | CTD | PMID:25181051|PMID:34947998|PMID:35192832 | Als2cl | Rat | bisphenol A | increases expression | ISO | Als2cl (Mus musculus) | 6480464 | bisphenol A results in increased expression of ALS2CL mRNA | CTD | PMID:33221593 | Als2cl | Rat | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of ALS2CL mRNA | CTD | PMID:30816183 | Als2cl | Rat | bisphenol F | decreases expression | ISO | Als2cl (Mus musculus) | 6480464 | bisphenol F results in decreased expression of ALS2CL mRNA | CTD | PMID:38685157 | Als2cl | Rat | bromobenzene | increases expression | EXP | | 6480464 | bromobenzene results in increased expression of ALS2CL mRNA | CTD | PMID:32479839 | Als2cl | Rat | Butylbenzyl phthalate | increases methylation | ISO | Als2cl (Mus musculus) | 6480464 | butylbenzyl phthalate results in increased methylation of ALS2CL intron | CTD | PMID:28392331 | Als2cl | Rat | C60 fullerene | increases expression | EXP | | 6480464 | fullerene C60 results in increased expression of ALS2CL mRNA | CTD | PMID:19167457 | Als2cl | Rat | cadmium atom | multiple interactions | ISO | Als2cl (Mus musculus) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of ALS2CL more ... | CTD | PMID:37236586 | Als2cl | Rat | cadmium dichloride | increases expression | ISO | ALS2CL (Homo sapiens) | 6480464 | Cadmium Chloride results in increased expression of ALS2CL mRNA | CTD | PMID:38568856 | Als2cl | Rat | cadmium dichloride | multiple interactions | ISO | Als2cl (Mus musculus) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of ALS2CL more ... | CTD | PMID:37236586 | Als2cl | Rat | calcitriol | multiple interactions | ISO | ALS2CL (Homo sapiens) | 6480464 | [Testosterone co-treated with Calcitriol] results in increased expression of ALS2CL mRNA | CTD | PMID:21592394 | Als2cl | Rat | calcitriol | increases expression | ISO | ALS2CL (Homo sapiens) | 6480464 | Calcitriol results in increased expression of ALS2CL mRNA | CTD | PMID:21592394|PMID:26485663 | Als2cl | Rat | camptothecin | increases expression | ISO | ALS2CL (Homo sapiens) | 6480464 | Camptothecin results in increased expression of ALS2CL mRNA | CTD | PMID:38460933 | Als2cl | Rat | carbon nanotube | increases expression | ISO | Als2cl (Mus musculus) | 6480464 | Nanotubes, Carbon results in increased expression of ALS2CL mRNA | CTD | PMID:25620056 | Als2cl | Rat | carbon nanotube | decreases expression | ISO | Als2cl (Mus musculus) | 6480464 | Nanotubes, Carbon analog results in decreased expression of ALS2CL mRNA; Nanotubes, Carbon results in decreased more ... | CTD | PMID:25554681 | Als2cl | Rat | chloroacetaldehyde | affects expression | ISO | ALS2CL (Homo sapiens) | 6480464 | chloroacetaldehyde affects the expression of ALS2CL mRNA | CTD | PMID:25596134 | Als2cl | Rat | chrysene | increases expression | ISO | Als2cl (Mus musculus) | 6480464 | chrysene results in increased expression of ALS2CL mRNA | CTD | PMID:26377693 | Als2cl | Rat | cidofovir anhydrous | affects expression | ISO | ALS2CL (Homo sapiens) | 6480464 | Cidofovir affects the expression of ALS2CL mRNA | CTD | PMID:25596134 | Als2cl | Rat | cisplatin | affects expression | ISO | ALS2CL (Homo sapiens) | 6480464 | Cisplatin affects the expression of ALS2CL mRNA | CTD | PMID:25596134 | Als2cl | Rat | cisplatin | multiple interactions | ISO | ALS2CL (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in increased expression of ALS2CL mRNA | CTD | PMID:27392435 | Als2cl | Rat | cisplatin | increases expression | ISO | ALS2CL (Homo sapiens) | 6480464 | Cisplatin results in increased expression of ALS2CL mRNA | CTD | PMID:27392435 | Als2cl | Rat | clodronic acid | affects expression | ISO | ALS2CL (Homo sapiens) | 6480464 | Clodronic Acid affects the expression of ALS2CL mRNA | CTD | PMID:25596134 | Als2cl | Rat | cobalt dichloride | increases expression | EXP | | 6480464 | cobaltous chloride results in increased expression of ALS2CL mRNA | CTD | PMID:24386269 | Als2cl | Rat | copper(II) sulfate | increases expression | ISO | ALS2CL (Homo sapiens) | 6480464 | Copper Sulfate results in increased expression of ALS2CL mRNA | CTD | PMID:19549813 | Als2cl | Rat | cyclosporin A | increases expression | ISO | ALS2CL (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of ALS2CL mRNA | CTD | PMID:25596134|PMID:27989131 | Als2cl | Rat | dexamethasone | multiple interactions | ISO | ALS2CL (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] more ... | CTD | PMID:28628672 | Als2cl | Rat | diarsenic trioxide | increases expression | ISO | Als2cl (Mus musculus) | 6480464 | Arsenic Trioxide results in increased expression of ALS2CL mRNA | CTD | PMID:39716349 | Als2cl | Rat | dioxygen | decreases expression | ISO | ALS2CL (Homo sapiens) | 6480464 | Oxygen deficiency results in decreased expression of ALS2CL mRNA | CTD | PMID:25596134 | Als2cl | Rat | doxorubicin | decreases expression | ISO | ALS2CL (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of ALS2CL mRNA | CTD | PMID:29803840 | Als2cl | Rat | doxorubicin | increases expression | ISO | Als2cl (Mus musculus) | 6480464 | Doxorubicin results in increased expression of ALS2CL mRNA | CTD | PMID:39631538 | Als2cl | Rat | elemental selenium | increases expression | ISO | ALS2CL (Homo sapiens) | 6480464 | Selenium results in increased expression of ALS2CL mRNA | CTD | PMID:19244175 | Als2cl | Rat | ethanol | increases expression | ISO | Als2cl (Mus musculus) | 6480464 | Ethanol results in increased expression of ALS2CL mRNA | CTD | PMID:30319688 | Als2cl | Rat | ethylparaben | increases expression | ISO | ALS2CL (Homo sapiens) | 6480464 | ethyl-p-hydroxybenzoate results in increased expression of ALS2CL mRNA | CTD | PMID:37690743 | Als2cl | Rat | flutamide | increases expression | EXP | | 6480464 | Flutamide results in increased expression of ALS2CL mRNA | CTD | PMID:24136188 | Als2cl | Rat | ifosfamide | affects expression | ISO | ALS2CL (Homo sapiens) | 6480464 | Ifosfamide affects the expression of ALS2CL mRNA | CTD | PMID:25596134 | Als2cl | Rat | indometacin | multiple interactions | ISO | ALS2CL (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] more ... | CTD | PMID:28628672 | Als2cl | Rat | leflunomide | increases expression | EXP | | 6480464 | leflunomide results in increased expression of ALS2CL mRNA | CTD | PMID:24136188 | Als2cl | Rat | methamphetamine | increases expression | ISO | Als2cl (Mus musculus) | 6480464 | Methamphetamine results in increased expression of ALS2CL mRNA | CTD | PMID:26307267 | Als2cl | Rat | methapyrilene | decreases expression | EXP | | 6480464 | Methapyrilene results in decreased expression of ALS2CL mRNA | CTD | PMID:30467583 | Als2cl | Rat | Nutlin-3 | multiple interactions | ISO | ALS2CL (Homo sapiens) | 6480464 | [Dactinomycin co-treated with nutlin 3] results in increased expression of ALS2CL mRNA | CTD | PMID:38460933 | Als2cl | Rat | okadaic acid | decreases expression | ISO | ALS2CL (Homo sapiens) | 6480464 | Okadaic Acid results in decreased expression of ALS2CL mRNA | CTD | PMID:38832940 | Als2cl | Rat | orphenadrine | affects expression | EXP | | 6480464 | Orphenadrine affects the expression of ALS2CL mRNA | CTD | PMID:23665939 | Als2cl | Rat | oxaliplatin | decreases expression | EXP | | 6480464 | oxaliplatin results in decreased expression of ALS2CL mRNA | CTD | PMID:25729387 | Als2cl | Rat | oxaliplatin | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of ALS2CL mRNA | CTD | PMID:25729387 | Als2cl | Rat | perfluorooctanoic acid | increases expression | ISO | ALS2CL (Homo sapiens) | 6480464 | perfluorooctanoic acid results in increased expression of ALS2CL mRNA | CTD | PMID:36326898 | Als2cl | Rat | pirinixic acid | increases expression | ISO | Als2cl (Mus musculus) | 6480464 | pirinixic acid results in increased expression of ALS2CL mRNA | CTD | PMID:18301758|PMID:18445702 | Als2cl | Rat | rac-lactic acid | increases expression | ISO | ALS2CL (Homo sapiens) | 6480464 | Lactic Acid results in increased expression of ALS2CL mRNA | CTD | PMID:30851411 | Als2cl | Rat | selenium atom | increases expression | ISO | ALS2CL (Homo sapiens) | 6480464 | Selenium results in increased expression of ALS2CL mRNA | CTD | PMID:19244175 | Als2cl | Rat | sodium arsenite | increases expression | ISO | ALS2CL (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of ALS2CL mRNA | CTD | PMID:38568856|PMID:39719251 | Als2cl | Rat | sodium arsenite | increases expression | ISO | Als2cl (Mus musculus) | 6480464 | sodium arsenite results in increased expression of ALS2CL mRNA | CTD | PMID:36209798 | Als2cl | Rat | sodium arsenite | decreases expression | ISO | ALS2CL (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of ALS2CL mRNA | CTD | PMID:34032870 | Als2cl | Rat | testosterone | multiple interactions | ISO | ALS2CL (Homo sapiens) | 6480464 | [Testosterone co-treated with Calcitriol] results in increased expression of ALS2CL mRNA | CTD | PMID:21592394 | Als2cl | Rat | testosterone | increases expression | ISO | ALS2CL (Homo sapiens) | 6480464 | Testosterone results in increased expression of ALS2CL mRNA | CTD | PMID:21592394 | Als2cl | Rat | tetraphene | affects expression | ISO | Als2cl (Mus musculus) | 6480464 | benz(a)anthracene affects the expression of ALS2CL mRNA | CTD | PMID:26377693 | Als2cl | Rat | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of ALS2CL mRNA | CTD | PMID:34492290 | Als2cl | Rat | thiram | increases expression | ISO | ALS2CL (Homo sapiens) | 6480464 | Thiram results in increased expression of ALS2CL mRNA | CTD | PMID:38568856 | Als2cl | Rat | titanium dioxide | increases methylation | ISO | Als2cl (Mus musculus) | 6480464 | titanium dioxide results in increased methylation of ALS2CL promoter | CTD | PMID:35295148 | Als2cl | Rat | topotecan | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of ALS2CL mRNA | CTD | PMID:25729387 | Als2cl | Rat | topotecan | decreases expression | EXP | | 6480464 | Topotecan results in decreased expression of ALS2CL mRNA | CTD | PMID:25729387 | Als2cl | Rat | triptonide | affects expression | ISO | Als2cl (Mus musculus) | 6480464 | triptonide affects the expression of ALS2CL mRNA | CTD | PMID:33045310 | Als2cl | Rat | valdecoxib | increases expression | EXP | | 6480464 | valdecoxib results in increased expression of ALS2CL mRNA | CTD | PMID:24136188 | Als2cl | Rat | valproic acid | increases methylation | ISO | ALS2CL (Homo sapiens) | 6480464 | Valproic Acid results in increased methylation of ALS2CL gene | CTD | PMID:29154799 | Als2cl | Rat | zoledronic acid | increases expression | ISO | ALS2CL (Homo sapiens) | 6480464 | zoledronic acid results in increased expression of ALS2CL mRNA | CTD | PMID:24714768|PMID:25596134 | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||






















