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Imported Disease Annotations - MGIObject Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Nsmce2 | Rat | Bloom syndrome | | ISS | RGD:1331905 | 13592920 | OMIM:210900 | MouseDO | | |
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Imported Disease Annotations - MGIObject Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Nsmce2 | Rat | Bloom syndrome | | ISS | RGD:1331905 | 13592920 | OMIM:210900 | MouseDO | | |
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# | Reference Title | Reference Citation |
1. | Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
2. | GOA pipeline | RGD automated data pipeline |
3. | ClinVar Automated Import and Annotation Pipeline | RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations |
4. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
PMID:12477932 | PMID:15489334 | PMID:16055714 | PMID:16810316 | PMID:17589526 | PMID:18086888 | PMID:19502785 | PMID:22751501 |
Nsmce2 (Rattus norvegicus - Norway rat) |
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NSMCE2 (Homo sapiens - human) |
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Nsmce2 (Mus musculus - house mouse) |
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Nsmce2 (Chinchilla lanigera - long-tailed chinchilla) |
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NSMCE2 (Pan paniscus - bonobo/pygmy chimpanzee) |
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NSMCE2 (Canis lupus familiaris - dog) |
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Nsmce2 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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NSMCE2 (Sus scrofa - pig) |
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NSMCE2 (Chlorocebus sabaeus - green monkey) |
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Nsmce2 (Heterocephalus glaber - naked mole-rat) |
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Variants in Nsmce2
1842 total Variants ![]() |
The detailed report is available here: | ![]() | Full Report | ![]() | CSV | ![]() | TAB | ![]() | Printer |
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
The following QTLs overlap with this region. | ![]() | Full Report | ![]() | CSV | ![]() | TAB | ![]() | Printer | ![]() | Gviewer |
D7Rat202 |
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D7Got73 |
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RH142770 |
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RH128753 |
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BF404967 |
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BE119183 |
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alimentary part of gastrointestinal system
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appendage
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circulatory system
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ectoderm
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endocrine system
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endoderm
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exocrine system
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hemolymphoid system
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hepatobiliary system
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integumental system
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mesenchyme
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mesoderm
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nervous system
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renal system
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reproductive system
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respiratory system
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9 | 11 | 49 | 113 | 91 | 90 | 59 | 25 | 59 | 6 | 218 | 97 | 93 | 45 | 60 | 31 |
Ensembl Acc Id: | ENSRNOT00000005376 ⟹ ENSRNOP00000005376 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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Ensembl Acc Id: | ENSRNOT00000086039 ⟹ ENSRNOP00000069742 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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Ensembl Acc Id: | ENSRNOT00000099968 ⟹ ENSRNOP00000085874 | ||||||||
Type: | CODING | ||||||||
Position: |
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Ensembl Acc Id: | ENSRNOT00000102133 ⟹ ENSRNOP00000097544 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | NM_001024876 ⟹ NP_001020047 | ||||||||||||||||||||||||||||
RefSeq Status: | PROVISIONAL | ||||||||||||||||||||||||||||
Type: | CODING | ||||||||||||||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_006241671 ⟹ XP_006241733 | ||||||||||||||||||||
Type: | CODING | ||||||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_017594758 ⟹ XP_017450247 | ||||||||||||||||
Type: | CODING | ||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_017594760 ⟹ XP_017450249 | ||||||||||||||||
Type: | CODING | ||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_039078795 ⟹ XP_038934723 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | XM_039078798 ⟹ XP_038934726 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | XM_039078799 ⟹ XP_038934727 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | XM_063263259 ⟹ XP_063119329 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063263260 ⟹ XP_063119330 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XR_001838681 | ||||||||||||||||
Type: | NON-CODING | ||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XR_005486582 | ||||||||||||
Type: | NON-CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | XR_010052954 | ||||||||
Type: | NON-CODING | ||||||||
Position: |
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RefSeq Acc Id: | XR_010052955 | ||||||||
Type: | NON-CODING | ||||||||
Position: |
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RefSeq Acc Id: | XR_010052956 | ||||||||
Type: | NON-CODING | ||||||||
Position: |
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RefSeq Acc Id: | XR_010052957 | ||||||||
Type: | NON-CODING | ||||||||
Position: |
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RefSeq Acc Id: | XR_010052958 | ||||||||
Type: | NON-CODING | ||||||||
Position: |
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RefSeq Acc Id: | NP_001020047 ⟸ NM_001024876 |
- UniProtKB: | Q4V8A0 (UniProtKB/Swiss-Prot), A6HRM3 (UniProtKB/TrEMBL), A0A0G2JW49 (UniProtKB/TrEMBL) |
- Sequence: |
RefSeq Acc Id: | XP_006241733 ⟸ XM_006241671 |
- Peptide Label: | isoform X8 |
- UniProtKB: | A0A8I6AS08 (UniProtKB/TrEMBL) |
- Sequence: |
RefSeq Acc Id: | XP_017450247 ⟸ XM_017594758 |
- Peptide Label: | isoform X1 |
- UniProtKB: | A0A8I6A069 (UniProtKB/TrEMBL), A6HRM2 (UniProtKB/TrEMBL) |
- Sequence: |
RefSeq Acc Id: | XP_017450249 ⟸ XM_017594760 |
- Peptide Label: | isoform X4 |
- Sequence: |
Ensembl Acc Id: | ENSRNOP00000005376 ⟸ ENSRNOT00000005376 |
Ensembl Acc Id: | ENSRNOP00000069742 ⟸ ENSRNOT00000086039 |
RefSeq Acc Id: | XP_038934726 ⟸ XM_039078798 |
- Peptide Label: | isoform X6 |
- UniProtKB: | A6HRM4 (UniProtKB/TrEMBL) |
RefSeq Acc Id: | XP_038934727 ⟸ XM_039078799 |
- Peptide Label: | isoform X7 |
RefSeq Acc Id: | XP_038934723 ⟸ XM_039078795 |
- Peptide Label: | isoform X3 |
Ensembl Acc Id: | ENSRNOP00000097544 ⟸ ENSRNOT00000102133 |
Ensembl Acc Id: | ENSRNOP00000085874 ⟸ ENSRNOT00000099968 |
RefSeq Acc Id: | XP_063119329 ⟸ XM_063263259 |
- Peptide Label: | isoform X2 |
RefSeq Acc Id: | XP_063119330 ⟸ XM_063263260 |
- Peptide Label: | isoform X5 |
Name | Modeler | Protein Id | AA Range | Protein Structure |
AF-Q4V8A0-F1-model_v2 | AlphaFold | Q4V8A0 | 1-247 | view protein structure |
eQTL | View at Phenogen | |
WGCNA | View at Phenogen | |
Tissue/Strain Expression | View at Phenogen |
RGD ID: | 13695367 | ||||||||
Promoter ID: | EPDNEW_R5883 | ||||||||
Type: | initiation region | ||||||||
Name: | Nsmce2_1 | ||||||||
Description: | NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase | ||||||||
SO ACC ID: | SO:0000170 | ||||||||
Source: | EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/) | ||||||||
Experiment Methods: | Single-end sequencing. | ||||||||
Position: |
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Database | Acc Id | Source(s) |
AGR Gene | RGD:1305156 | AgrOrtholog |
BioCyc Gene | G2FUF-33289 | BioCyc |
Ensembl Genes | ENSRNOG00000003964 | Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot |
Ensembl Transcript | ENSRNOT00000005376 | ENTREZGENE |
ENSRNOT00000005376.6 | UniProtKB/Swiss-Prot | |
ENSRNOT00000086039 | ENTREZGENE | |
ENSRNOT00000099968 | ENTREZGENE | |
ENSRNOT00000102133 | ENTREZGENE | |
Gene3D-CATH | 3.30.40.10 | UniProtKB/Swiss-Prot |
IMAGE_CLONE | IMAGE:7458086 | IMAGE-MGC_LOAD |
InterPro | Nse2(Mms21) | UniProtKB/Swiss-Prot |
Ubox_domain | UniProtKB/Swiss-Prot | |
Znf_MIZ | UniProtKB/Swiss-Prot | |
Znf_RING/FYVE/PHD | UniProtKB/Swiss-Prot | |
KEGG Report | rno:299957 | UniProtKB/Swiss-Prot |
MGC_CLONE | MGC:114542 | IMAGE-MGC_LOAD |
NCBI Gene | 299957 | ENTREZGENE |
PANTHER | E3 SUMO-PROTEIN LIGASE NSE2 | UniProtKB/Swiss-Prot |
PTHR21330 | UniProtKB/Swiss-Prot | |
Pfam | zf-Nse | UniProtKB/Swiss-Prot |
PhenoGen | Nsmce2 | PhenoGen |
PROSITE | ZF_SP_RING | UniProtKB/Swiss-Prot |
RatGTEx | ENSRNOG00000003964 | RatGTEx |
SMART | Ubox | UniProtKB/Swiss-Prot |
Superfamily-SCOP | RING/U-box | UniProtKB/Swiss-Prot |
UniProt | A0A0G2JW49 | ENTREZGENE, UniProtKB/TrEMBL |
A0A8I6A069 | ENTREZGENE, UniProtKB/TrEMBL | |
A0A8I6AS08 | ENTREZGENE, UniProtKB/TrEMBL | |
A6HRM2 | ENTREZGENE, UniProtKB/TrEMBL | |
A6HRM3 | ENTREZGENE, UniProtKB/TrEMBL | |
A6HRM4 | ENTREZGENE, UniProtKB/TrEMBL | |
NSE2_RAT | UniProtKB/Swiss-Prot, ENTREZGENE |
Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
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2015-08-13 | Nsmce2 | NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase | Nsmce2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
2008-03-06 | Nsmce2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | RGD1305156 | similar to RIKEN cDNA 1110014D18 | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
2005-12-06 | RGD1305156 | similar to RIKEN cDNA 1110014D18 | RGD1305156_predicted | similar to RIKEN cDNA 1110014D18 (predicted) | Symbol and Name updated | 1559027 | APPROVED |
2005-01-20 | RGD1305156_predicted | similar to RIKEN cDNA 1110014D18 (predicted) | LOC299957_predicted | Symbol and Name status set to approved | 1331353 | APPROVED | |
2005-01-12 | LOC299957_predicted | similar to RIKEN cDNA 1110014D18 (predicted) | Symbol and Name status set to provisional | 70820 | PROVISIONAL |