Nsmce2 (NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase)

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Gene: Nsmce2 (NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase) Rattus norvegicus

Analyze

Symbol:

Nsmce2

Name:

NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase

RGD ID:

1305156

Description:

Predicted to enable SUMO ligase activity. Predicted to be involved in several processes, including DNA recombination; positive regulation of cell cycle process; and protein sumoylation. Predicted to be located in PML body and chromosome, telomeric region. Predicted to be part of Smc5-Smc6 complex. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in Seckel syndrome 10. Orthologous to human NSMCE2 (NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase); INTERACTS WITH bisphenol A; Cuprizon; finasteride.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

E3 SUMO-protein ligase NSE2; E3 SUMO-protein transferase NSE2; LOC299957; MGC114542; MMS21 homolog; non-SMC element 2 homolog; non-SMC element 2, MMS21 homolog; non-SMC element 2, MMS21 homolog (S. cerevisiae); non-structural maintenance of chromosomes element 2 homolog; RGD1305156; similar to RIKEN cDNA 1110014D18

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	7	90,936,112 - 91,173,435 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	90,936,112 - 91,164,899 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	7	92,826,087 - 93,044,522 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	95,027,272 - 95,245,732 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	94,854,556 - 95,076,868 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	7	99,677,295 - 99,900,765 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	99,677,290 - 99,900,764 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	7	100,263,539 - 100,486,903 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	7	96,167,635 - 96,393,594 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	7	96,201,864 - 96,427,823 (+)	NCBI
Celera	7	87,697,871 - 87,919,520 (+)	NCBI		Celera
Cytogenetic Map	7	q33	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Bloom syndrome (ISS)

Developmental Disabilities (ISO)

genetic disease (ISO)

hereditary spastic paraplegia 8 (ISO)

Seckel syndrome 10 (ISO)

trichorhinophalangeal syndrome type I (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-epigallocatechin 3-gallate (ISO)

1,2-dimethylhydrazine (ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

4,4'-sulfonyldiphenol (ISO)

acrylamide (ISO)

aflatoxin B1 (ISO)

aristolochic acid A (ISO)

arsane (ISO)

arsenic atom (ISO)

arsenite(3-) (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

carbon nanotube (ISO)

chlorpyrifos (ISO)

cisplatin (ISO)

Cuprizon (EXP)

cyclosporin A (ISO)

dicrotophos (ISO)

doxorubicin (ISO)

finasteride (EXP)

flutamide (EXP)

folic acid (ISO)

fulvestrant (ISO)

ketamine (EXP)

oxaliplatin (EXP)

ozone (ISO)

paracetamol (ISO)

pirinixic acid (ISO)

potassium chromate (ISO)

resveratrol (ISO)

silver atom (ISO)

silver(0) (ISO)

sodium arsenate (ISO)

sunitinib (ISO)

topotecan (EXP)

trichloroethene (EXP)

urethane (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cell division (IEA)

cellular senescence (IEA,ISO,ISS)

double-strand break repair via homologous recombination (IBA,IEA,ISO,ISS)

double-strand break repair via nonhomologous end joining (ISO)

positive regulation of maintenance of mitotic sister chromatid cohesion (IEA,ISO,ISS)

positive regulation of mitotic metaphase/anaphase transition (IEA,ISO,ISS)

protein sumoylation (IBA,IEA)

protein ubiquitination (IEA)

telomere maintenance via recombination (IEA,ISO,ISS)

Cellular Component

chromosome, telomeric region (IEA,ISO,ISS)

nuclear body (ISO)

nucleoplasm (ISO)

nucleus (IBA,IEA)

PML body (IEA,ISO,ISS)

Smc5-Smc6 complex (IBA,IEA,ISO,ISS)

Molecular Function

protein binding (ISO)

SUMO ligase activity (IBA)

SUMO transferase activity (IEA,ISO,ISS)

ubiquitin-protein transferase activity (IEA)

zinc ion binding (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	GOA pipeline	RGD automated data pipeline
3.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12477932	PMID:15489334	PMID:16055714	PMID:16810316	PMID:17589526	PMID:18086888	PMID:19502785	PMID:22751501

Genomics

Comparative Map Data

Nsmce2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	7	90,936,112 - 91,173,435 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	90,936,112 - 91,164,899 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	7	92,826,087 - 93,044,522 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	95,027,272 - 95,245,732 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	94,854,556 - 95,076,868 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	7	99,677,295 - 99,900,765 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	99,677,290 - 99,900,764 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	7	100,263,539 - 100,486,903 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	7	96,167,635 - 96,393,594 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	7	96,201,864 - 96,427,823 (+)	NCBI
Celera	7	87,697,871 - 87,919,520 (+)	NCBI		Celera
Cytogenetic Map	7	q33	NCBI

NSMCE2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	8	125,091,860 - 125,367,120 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	8	125,091,679 - 125,367,120 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	8	126,104,102 - 126,379,362 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	8	126,173,277 - 126,448,544 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	8	122,293,246 - 122,568,218 (+)	NCBI		Celera
Cytogenetic Map	8	q24.13	NCBI
HuRef	8	121,427,877 - 121,703,222 (+)	NCBI		HuRef
CHM1_1	8	126,144,698 - 126,419,607 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	8	126,225,519 - 126,500,604 (+)	NCBI		T2T-CHM13v2.0

Nsmce2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	15	59,246,047 - 59,473,538 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	15	59,246,096 - 59,473,533 (+)	Ensembl		GRCm39 Ensembl
GRCm38	15	59,374,198 - 59,601,689 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	15	59,374,247 - 59,601,684 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	15	59,205,753 - 59,433,239 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	15	59,203,928 - 59,431,364 (+)	NCBI		MGSCv36	mm8
Celera	15	60,905,217 - 61,133,508 (+)	NCBI		Celera
Cytogenetic Map	15	D1	NCBI
cM Map	15	25.19	NCBI

Nsmce2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955461	201,764 - 451,776 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955461	199,356 - 451,716 (+)	NCBI	ChiLan1.0	ChiLan1.0

NSMCE2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1	8	118,026,022 - 118,300,121 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	8	121,777,986 - 122,052,094 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	8	124,529,245 - 124,803,354 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	8	124,529,268 - 124,803,114 (+)	Ensembl	panpan1.1		panPan2

NSMCE2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	13	23,078,143 - 23,288,302 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	13	23,078,173 - 23,288,304 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	13	23,042,326 - 23,261,292 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	13	23,419,977 - 23,634,235 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	13	23,420,016 - 23,634,235 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	13	23,140,666 - 23,355,264 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	13	23,249,898 - 23,462,275 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	13	23,492,960 - 23,706,136 (+)	NCBI		UU_Cfam_GSD_1.0

Nsmce2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405303	15,021,038 - 15,241,228 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936470	22,445,433 - 22,667,559 (-)	Ensembl	SpeTri2.0
SpeTri2.0	NW_004936470	22,447,278 - 22,667,302 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

NSMCE2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	4	14,358,651 - 14,598,077 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	4	14,359,323 - 14,598,192 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	4	14,948,825 - 15,035,641 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

NSMCE2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	8	119,679,090 - 119,949,212 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	8	119,691,106 - 119,949,587 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666039	20,225,964 - 20,495,843 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Nsmce2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624735	29,913,423 - 30,151,922 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624735	29,915,007 - 30,166,564 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Nsmce2
879 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	152
Count of miRNA genes:	112
Interacting mature miRNAs:	121
Transcripts:	ENSRNOT00000005376
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
634336	Anxrr17	Anxiety related response QTL 17	3.66		locomotor behavior trait (VT:0001392)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	7	924703	115097879	Rat
1643004	Pain2	Pain QTL 2	1		mechanical nociception trait (VT:0002734)	self mutilation severity score (CMO:0002145)	7	9462246	98011544	Rat
61357	Bp38	Blood pressure QTL 38	1.6	0.052	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	7	41333674	119109060	Rat
1358361	Sradr5	Stress Responsive Adrenal Weight QTL 5	5.55		adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	7	43747012	108555253	Rat
1300179	Kidm5	Kidney mass QTL 5	3.51		kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	7	43747012	135012528	Rat
1300149	Cm6	Cardiac mass QTL 6	4.09		heart mass (VT:0007028)	heart left ventricle weight to body weight ratio (CMO:0000530)	7	43747099	102228765	Rat
631504	Cm27	Cardiac mass QTL 27	3.45		heart left ventricle mass (VT:0007031)	heart left ventricle wet weight (CMO:0000071)	7	44421311	118198041	Rat
738030	Anxrr8	Anxiety related response QTL 8	4.1		exploratory behavior trait (VT:0010471)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	7	46590070	91590070	Rat
2293696	Bmd32	Bone mineral density QTL 32	5.1	0.0001	femur strength trait (VT:0010010)	femoral neck polar moment of inertia (CMO:0001670)	7	47651439	92651439	Rat
2293707	Bss32	Bone structure and strength QTL 32	7.64	0.0001	femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	7	47651439	92651439	Rat
2300178	Bmd54	Bone mineral density QTL 54	5.3	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	7	47651439	92651439	Rat
2293644	Bmd29	Bone mineral density QTL 29	5.4	0.0001	femur size trait (VT:1000369)	femoral neck cross-sectional area (CMO:0001697)	7	47651439	92651439	Rat
2293667	Bss42	Bone structure and strength QTL 42	7.25	0.0001	lumbar vertebra size trait (VT:0010518)	lumbar vertebra cross-sectional area (CMO:0001689)	7	47651439	92651439	Rat
2293678	Bss24	Bone structure and strength QTL 24	6.71	0.0001	femur morphology trait (VT:0000559)	femur cross-sectional area (CMO:0001661)	7	47651439	92651439	Rat
2293685	Bmd21	Bone mineral density QTL 21	4.2	0.0003	femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	7	47651439	92651439	Rat
1300151	Bp181	Blood pressure QTL 181	3.36		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	7	53612714	103945643	Rat
2317035	Aia16	Adjuvant induced arthritis QTL 16	2.71		joint integrity trait (VT:0010548)	right rear ankle joint diameter (CMO:0002150)	7	59238038	104238038	Rat
1298528	Bp169	Blood pressure QTL 169		0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	7	61074194	106074194	Rat
1559283	Emca4	Estrogen-induced mammary cancer QTL 4	3.7		mammary gland integrity trait (VT:0010552)	percentage of study population developing mammary tumors during a period of time (CMO:0000948)	7	62004452	101773158	Rat
1576303	Ept7	Estrogen-induced pituitary tumorigenesis QTL 7	3.7		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	7	62004452	101773158	Rat
70173	Niddm19	Non-insulin dependent diabetes mellitus QTL 19	4.33	0.00005	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	7	64002457	135012528	Rat
2316947	Rf58	Renal function QTL 58	7.8		kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	7	68938720	113886318	Rat
2316952	Pur22	Proteinuria QTL 22	5.2		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	7	68938720	113886318	Rat
2316955	Stl24	Serum triglyceride level QTL 24	7.1		blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	7	68938720	113886318	Rat
631540	Bw9	Body weight QTL 9	4.5		body mass (VT:0001259)	body weight (CMO:0000012)	7	69736226	117455174	Rat
1357338	Stl17	Serum triglyceride level QTL 17	3.23		blood triglyceride amount (VT:0002644)	serum triglyceride level (CMO:0000360)	7	69736356	112729554	Rat
634331	Pia17	Pristane induced arthritis QTL 17	4.7		joint integrity trait (VT:0010548)	arthritic paw count (CMO:0001460)	7	73829340	130221005	Rat
7411654	Foco25	Food consumption QTL 25	9.3	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	7	75918751	120918751	Rat
7411607	Foco15	Food consumption QTL 15		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	7	75918751	120918751	Rat
724537	Niddm52	Non-insulin dependent diabetes mellitus QTL 52		0.02	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	7	80221299	93595843	Rat
1641908	Teswt1	Testicular weight QTL 1	3.28		testis mass (VT:1000644)	both testes wet weight (CMO:0000175)	7	80221299	94811326	Rat
631529	Tls2	T-lymphoma susceptibility QTL 2	0	0.001	thymus integrity trait (VT:0010555)	percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)	7	80221299	109401111	Rat
1331746	Kidm9	Kidney mass QTL 9	3.934		kidney mass (VT:0002707)	right kidney wet weight (CMO:0000082)	7	80221299	112308525	Rat
1331728	Bp214	Blood pressure QTL 214	2.825		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	80221299	124373579	Rat
1331768	Kidm10	Kidney mass QTL 10	4.62096		kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	7	80221299	125221299	Rat
2317052	Aia17	Adjuvant induced arthritis QTL 17	2.13		joint integrity trait (VT:0010548)	left rear ankle joint diameter (CMO:0002149)	7	81737938	126737938	Rat
634322	Bw12	Body weight QTL 12	0		body mass (VT:0001259)	body weight (CMO:0000012)	7	83153392	128153392	Rat
1358891	Bp265	Blood pressure QTL 265	2.21		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	83591953	134666232	Rat
1358914	Bp266	Blood pressure QTL 266			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	83591953	134666232	Rat
71114	Niddm14	Non-insulin dependent diabetes mellitus QTL 14	4.5		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	7	84257275	129257275	Rat
2298475	Eau6	Experimental allergic uveoretinitis QTL 6		0.0029	uvea integrity trait (VT:0010551)	experimental autoimmune uveitis score (CMO:0001504)	7	84257275	129257275	Rat
1558655	Swd4	Spike wave discharge measurement QTL 4	3.68	0.0002	brain electrophysiology trait (VT:0010557)	brain spike-and-wave discharge severity grade (CMO:0001988)	7	86983365	131983365	Rat
10450828	Scl79	Serum cholesterol level QTL 79	3.5	0.001	blood HDL cholesterol amount (VT:0000184)	blood low density lipoprotein cholesterol level (CMO:0000053)	7	89867376	101773158	Rat
1549899	Stresp8	Stress response QTL 8	4.37	0.0008	stress-related behavior trait (VT:0010451)	defensive burying duration (CMO:0001961)	7	90482196	135012528	Rat

Markers in Region

D7Rat202

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	7	91,139,876 - 91,140,102 (+)	MAPPER	mRatBN7.2
Rnor_6.0	7	99,881,975 - 99,882,200	NCBI	Rnor6.0
Rnor_5.0	7	100,468,113 - 100,468,338	UniSTS	Rnor5.0
RGSC_v3.4	7	96,374,799 - 96,375,025	RGD	RGSC3.4
RGSC_v3.4	7	96,374,800 - 96,375,025	UniSTS	RGSC3.4
RGSC_v3.1	7	96,409,029 - 96,409,255	RGD
Celera	7	87,900,714 - 87,900,939	UniSTS
SHRSP x BN Map	7	52.31	RGD
SHRSP x BN Map	7	52.31	UniSTS
Cytogenetic Map	7	q33	UniSTS

D7Got73

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	7	90,995,773 - 90,995,980 (+)	MAPPER	mRatBN7.2
Rnor_6.0	7	99,736,992 - 99,737,198	NCBI	Rnor6.0
Rnor_5.0	7	100,323,130 - 100,323,336	UniSTS	Rnor5.0
RGSC_v3.4	7	96,228,858 - 96,229,065	RGD	RGSC3.4
RGSC_v3.4	7	96,228,859 - 96,229,065	UniSTS	RGSC3.4
RGSC_v3.1	7	96,263,088 - 96,263,295	RGD
Celera	7	87,757,197 - 87,757,403	UniSTS
RH 2.0 Map	7	559.1	RGD
Cytogenetic Map	7	q33	UniSTS

RH142770

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	7	91,023,331 - 91,023,598 (+)	MAPPER	mRatBN7.2
Rnor_6.0	7	99,764,392 - 99,764,658	NCBI	Rnor6.0
Rnor_5.0	7	100,350,530 - 100,350,796	UniSTS	Rnor5.0
RGSC_v3.4	7	96,256,413 - 96,256,679	UniSTS	RGSC3.4
Celera	7	87,784,726 - 87,784,992	UniSTS
Cytogenetic Map	7	q33	UniSTS

RH128753

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	7	91,158,412 - 91,158,566 (+)	MAPPER	mRatBN7.2
Rnor_6.0	7	99,900,503 - 99,900,656	NCBI	Rnor6.0
Rnor_5.0	7	100,486,641 - 100,486,794	UniSTS	Rnor5.0
RGSC_v3.4	7	96,393,332 - 96,393,485	UniSTS	RGSC3.4
Celera	7	87,919,258 - 87,919,411	UniSTS
Cytogenetic Map	7	q33	UniSTS

BF404967

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	7	91,043,803 - 91,044,047 (+)	MAPPER	mRatBN7.2
Rnor_6.0	7	99,785,157 - 99,785,400	NCBI	Rnor6.0
Rnor_5.0	7	100,371,295 - 100,371,538	UniSTS	Rnor5.0
RGSC_v3.4	7	96,276,885 - 96,277,128	UniSTS	RGSC3.4
Celera	7	87,805,191 - 87,805,434	UniSTS
RH 3.4 Map	7	652.1	UniSTS
Cytogenetic Map	7	q33	UniSTS

BE119183

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	7	91,077,386 - 91,077,573 (+)	MAPPER	mRatBN7.2
Rnor_6.0	7	99,819,309 - 99,819,495	NCBI	Rnor6.0
Rnor_5.0	7	100,405,447 - 100,405,633	UniSTS	Rnor5.0
RGSC_v3.4	7	96,311,836 - 96,312,022	UniSTS	RGSC3.4
Celera	7	87,838,310 - 87,838,496	UniSTS
RH 3.4 Map	7	651.27	UniSTS
Cytogenetic Map	7	q33	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	3	36	57	41	19	41	2	2	74	35	41	11	2
Low		7					6	9					6
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001024876	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006241671	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017594758	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017594759	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017594760	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017594761	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039078794	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039078795	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039078796	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039078797	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039078798	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039078799	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_001838681	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005486582	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC097477	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473950	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000185	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000005376 ⟹ ENSRNOP00000005376

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	7	90,936,127 - 91,158,668 (+)	Ensembl
Rnor_6.0 Ensembl	7	99,677,335 - 99,900,764 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000086039 ⟹ ENSRNOP00000069742

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	7	90,936,112 - 91,164,899 (+)	Ensembl
Rnor_6.0 Ensembl	7	99,677,290 - 99,892,370 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000099968 ⟹ ENSRNOP00000085874

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	7	90,936,127 - 91,158,668 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000102133 ⟹ ENSRNOP00000097544

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	7	90,936,163 - 91,101,133 (+)	Ensembl

RefSeq Acc Id:

NM_001024876 ⟹ NP_001020047

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	7	90,936,198 - 91,158,675 (+)	NCBI
Rnor_6.0	7	99,677,335 - 99,900,765 (+)	NCBI
Rnor_5.0	7	100,263,539 - 100,486,903 (+)	NCBI
RGSC_v3.4	7	96,167,635 - 96,393,594 (+)	RGD
Celera	7	87,697,871 - 87,919,520 (+)	RGD

Sequence:

show sequence

TGAGGAAAGGAATCGGGGTCTGGGTGTGCGACGTTCGGCAAGATATCGCTGAGCTAGGTGGGAC
AGCCAGATTTCAAAGATGCCAGGACGGTCCAGTACAAATTCAGGTTCTACTCGTTACATATCCT
TCAGTGGTGTAGAGTCAGCTCTCTCCTCCTTAAAAACCTTCCAGTCCTGTATCAGCTCTGGGAT
GGACACAGTTTCTAGTGTTGCCTTGGACCTTGTGGAGACCCAAACTGAAGTGAGTAGTGAGTAC
AGTATGGACAAGGCCATGGTTGAATTTGCTAAAATGGATCGAGAACTAAACCATTATGTTAAGG
CTGTCCAGTCTACAATAAATCATGTAAAAGAAGAACGTCCAGAAAAAGTACCAGATTTAAAATT
ACTGGTGGAGAAGAAATTTTTGGCTTTACAGGATAAGAACTCTGACGCCGACTTTAAAGAGAAT
GAAAAGTTCGTGCAGTTTAAGCAGCAGCTGCGGGAGCTGAAGAAGCAATATGGTATTCATGCAG
ACAGAGAGAATGATGGGATAGAAGGAATGGATGAAGATATGATTGTGACCCAGAGCCAAACCAA
TTTCATCTGCCCCATAACACAGTTGGAAATGAAGAAGCCAGTGAAAAATAAAATGTGTGGCCAC
ACATACGAAGAGGAAGCCATTGTTCGCATGATTGAATCCAAGCATAAGAGGAAGAAGAAGGCTT
GTTGCCCAAAAATTGGCTGTAGCCACACAGACATGAGAATGTCAGATCTCATTCCGGATGAAGC
CCTGAGAAGGGCAATCGAGAGCCACAACAAGAAGAAAAAGCGCCACTCCGAGTAGGAGCCAGCC
CCCTGCCCACAGGGGTGTCAGCAGCCTACCTCCCCACAGCCACCAGAGAGTGAGCGTTCACAGC
AATAGGCCCGGCAAGCTCTGCAGTGACCCTCAAGGCTAATTGTAATTGAAAGCATTTTTTAAGT
TACACAATAAAAACACAAGTACATTATAGTCTTTATTTTCAAGTGCTCTGAAATTTTAAATAAA
ACTTTGATAATCTTCAGCACGAAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_006241671 ⟹ XP_006241733

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	7	90,936,133 - 91,101,143 (+)	NCBI
Rnor_6.0	7	99,677,295 - 99,843,064 (+)	NCBI
Rnor_5.0	7	100,263,539 - 100,486,903 (+)	NCBI

Sequence:

show sequence

AGAGCGCGCGCGGGGCGTTTCAGCCACTGGAGAAGTAGGCTGAGGAAAGGAATCGGGGTCTGGG
TGTGCGACGTTCGGCAAGATATCGCTGAGCTAGGTGGGACAGCCAGATTTCAAAGATGCCAGGA
CGGTCCAGTACAAATTCAGGTTCTACTCGTTACATATCCTTCAGTGGTGTAGAGTCAGCTCTCT
CCTCCTTAAAAACCTTCCAGTCCTGTATCAGCTCTGGGATGGACACAGTTTCTAGTGTTGCCTT
GGACCTTGTGGAGACCCAAACTGAAGTGAGTAGTGAGTACAGTATGGACAAGGCCATGGTTGAA
TTTGCTAAAATGGATCGAGAACTAAACCATTATGTTAAGGCTGTCCAGTCTACAATAAATCATG
TAAAAGAAGAACGTCCAGAAAAAGTACCAGATTTAAAATTACTGGTGGAGAAGAAATTTTTGGC
TTTACAGGATAAGAACTCTGACGCCGACTTTAAAGAGAATGAAAAGTTCGTGCAGTTTAAGCAG
CAGCTGCGGGAGCTGAAGAAGCAATGAACTGCCAGGCTGTTTCCCACAGCGAGGGCGCCATTTT
ACATTTCCACCAGCAGTGTATGAGGGTTCCAATTGCTCCACGTCCTCGCCAGCACTTGTTACTG
CCTGTCCTCCTTACTGTAGCCACTGTAGTGTGTGTGAAGTGGTGTCTCATTGTTTTGCCTTACA
TTTCTCTGATGGATTAATATCGTGGTGTTTATATTACTAACCTAGGGTTTAAATCTTATACTTT
GATATAGAAACCACTGTATAATACTGGATTGGTTTTTCTGAAGCAAAATCATAGTTCTGTATGA
GATAAATGTTATTCATGAAGTTATACTTGGGAAAAAAAAACCCATAAAGTAAAACTGACCTAGG
ATGAAGACAGTCACCTGAAACATCTGTCTTGCAGTATGAATCCACCCGCAGTGTTCCTTATCTG
AGCTACTAAAGTGCTATTGTGTGAATCCACCCGCAGTGTTCCTTATCTGAGCTACTAAAGTGCT
ATTGTGTGACATTTACTGGATAATCCAGACAGCACTTTGACTAAAACCACAATATGGTGTCACT
AGGTAAACACTTGGAAATGGAAATGTGTGTCTCTTCTGGTTTTATCAGTTGAGATTAAAGGTGG
TTTATAGTATAGGAAACCTTTTCTCCACACTCTGTATCTCAATGTGGGCCAATAATCTGTCACC
TGAAACTACTTAAAATAGGTTGGGCTTTCTTGACTGTCCTGTTGCTGTGATGACATCAGGATCT
AACTGCAGAAGGGAGAAAAGGACGTTTCTCTGACTTGTTTGCCTCCTTGTCCTTTGTCCCCAGT
TAAAAGCACTGCCCTTTTCAGCCCTTACCTCTGTCTGTTTCTCAGATGTTTTCTACATCAGTAG
CATCATCTGTCACTCACCCTGTGGAGCTCCTCGTCCGGTCATAATTGTTTCTGTCAAGGAAAGA
ACACCAGGTGCAGCTTGGCAGTGTGTGAGCTTCACCAGCCCTAGACAGGTACAGAATGAAGAAG
GGGCTGGTGGAGGAGAAAACGAATCTCGAACCAAATTCAGAAGATCTTTCTTTTTAAAAAGAGT
CTCAGGATGCCTCTGAAAGCTCCCCCAGGACAGACAGCTTCACAGGAGACCAGTCCTCCTCTCT
GGCACATAGAGAGCCTCACCTAGAGCTAAGCTTCCTGTGTGCTATGCTTTCCTGACTGCGTCTG
GCACTGTGTGCAGAAGGCCTGCAGGGGACCAAGGAGAAGAGAGAAAGAAAGAGTAGATAGTTCT
TCCCTTCCTAGTTTCTACCTCTGCCTTATCTGCCCCTCAACTTCATGTGGGCCTGAGGCTGGGC
TGGGGAGTGGTTATGAAGAATAACTAGATTGATTGGCAGATTAACTTGAATTCTGCCACCCCCA
AAGTAATGGTAGACAACAACTTGAGACACTTGAGCTGGTGCAAGCCTTTGTGAACTCTCTTTTG
ACACTTTTTTTGTTAATTGAAATACTGCTCTGGGTGAAGCAAGCACATCACACCTTCGAAAGCC
CCTGGACAACTGGATAACCCCAGACCCTGTGCCTTCAGAACGATTGCAGAGGAACTAGATAGTA
ACCATTGGTATGTTAGTAGGAACTGTGGTTTGGTCCTGACTTTTAAAATGACTAGCCCTCAAGT
AACAGGAAAGTAAATGATGTTCACTTCCTGAATTGGACTGTGTGCTAAGACAGTTGAATAGCTG
TGCATGGGCTCCCAGTTCATTTTTTCCACAGCCCTCTGAGATGACACAGTTGTCCTTCAAGTGA
GCTATAATGAAACTTAGTGCTTGCCTGCCATATCCAGTTTGCCCTTAGCTCAACACCCATCTGT
CTGTGACCTGATATAGTGACTGTGGTGGCTCCCCCATGTCCTATGAGGAATGGTGGGGAGGGGT
AGGGATAGGAGCCAAGAGAGGCTGTAAAGGGCTGCATAGCAGGCTTACCCACATTAGAAGCCAA
CTGATGGGTTTGGAACTTATTTTTGGTTGGATTTTGAGTGTCCTTGCAGCAATTTTTACAGAAA
GCTTCAAGCTCCTTTCCCTCACATCCCCACAGAAGGGAATGATGGCTGAGGAAAAGCAGATTCA
TTTGTTCCTGTAACAAAATAATCAAATGTGTTTCTGTGGAACAAAAACAAATTTGAAGTTTTGC
TTGTTCTTTTCTATTATGAAATTGAAATAAAAAAGGAATGTCACCTGTA

hide sequence

RefSeq Acc Id:

XM_017594758 ⟹ XP_017450247

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	7	90,936,133 - 91,158,675 (+)	NCBI
Rnor_6.0	7	99,677,295 - 99,900,765 (+)	NCBI

Sequence:

show sequence

AGAGCGCGCGCGGGGCGTTTCAGCCACTGGAGAAGTAGGCTGAGGAAAGGAATCGGGGTCTGGG
TGTGCGACGTTCGGCAAGATATCGCTGAGCTAGGTGGGACAGCCAGATTTCAAAGATGCCAGGA
CGGTCCAGTACAAATTCAGGTTCTACTCGTTACATATCCTTCAGTGGTGTAGAGTCAGCTCTCT
CCTCCTTAAAAACCTTCCAGTCCTGTATCAGCTCTGGGATGGACACAGTTTCTAGTGTTGCCTT
GGACCTTGTGGAGACCCAAACTGAAGTGAGTAGTGAGTACAGTATGGACAAGGCCATGGTTGAA
TTTGCTAAAATGGATCGAGAACTAAACCATTATGTTAAGGCTGTCCAGTCTACAATAAATCATG
TAAAAGAAGAACGTCCAGAAAAAGTACCAGATTTAAAATTACTGGTGGAGAAGAAATTTTTGGC
TTTACAGGATAAGAACTCTGACGCCGACTTTAAAGAGAATGAAAAGTTCGTGCAGTTTAAGCAG
CAGCTGCGGGAGCTGAAGAAGCAATTAGTGAAACCCAGAGAAGATGGAAGACACAATGAATTCG
ACCCGAATAAGGATTCCAGTAGAACAGGCAATGAACGAGATGGTATTCATGCAGACAGAGAGAA
TGATGGGATAGAAGGAATGGATGAAGATATGATTGTGACCCAGAGCCAAACCAATTTCATCTGC
CCCATAACACAGTTGGAAATGAAGAAGCCAGTGAAAAATAAAATGTGTGGCCACACATACGAAG
AGGAAGCCATTGTTCGCATGATTGAATCCAAGCATAAGAGGAAGAAGAAGGCTTGTTGCCCAAA
AATTGGCTGTAGCCACACAGACATGAGAATGTCAGATCTCATTCCGGATGAAGCCCTGAGAAGG
GCAATCGAGAGCCACAACAAGAAGAAAAAGCGCCACTCCGAGTAGGAGCCAGCCCCCTGCCCAC
AGGGGTGTCAGCAGCCTACCTCCCCACAGCCACCAGAGAGTGAGCGTTCACAGCAATAGGCCCG
GCAAGCTCTGCAGTGACCCTCAAGGCTAATTGTAATTGAAAGCATTTTTTAAGTTACACAATAA
AAACACAAGTACATTATAGTCTTTATTTTCAAGTGCTCTGAAATTTTAAATAAAACTTTGATAA
TCTTCAGCACGA

hide sequence

RefSeq Acc Id:

XM_017594760 ⟹ XP_017450249

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	7	90,936,133 - 91,101,143 (+)	NCBI
Rnor_6.0	7	99,677,295 - 99,843,064 (+)	NCBI

Sequence:

show sequence

AGAGCGCGCGCGGGGCGTTTCAGCCACTGGAGAAGTAGGCTGAGGAAAGGAATCGGGGTCTGGG
TGTGCGACGTTCGGCAAGATATCGCTGAGCTAGGTGGGACAGCCAGATTTCAAAGATGCCAGGA
CGGTCCAGTACAAATTCAGGTTCTACTCGTTACATATCCTTCAGTGGTGTAGAGTCAGCTCTCT
CCTCCTTAAAAACCTTCCAGTCCTGTATCAGCTCTGGGATGGACACAGTTTCTAGTGTTGCCTT
GGACCTTGTGGAGACCCAAACTGAAGTGAGTAGTGAGTACAGTATGGACAAGGCCATGGTTGAA
TTTGCTAAAATGGATCGAGAACTAAACCATTATGTTAAGGCTGTCCAGTCTACAATAAATCATG
TAAAAGAAGAACGTCCAGAAAAAGTACCAGATTTAAAATTACTGGTGGAGAAGAAATTTTTGGC
TTTACAGGATAAGAACTCTGACGCCGACTTTAAAGAGAATGAAAAGTTCGTGCAGTTTAAGCAG
CAGCTGCGGGAGCTGAAGAAGCAATTAGTGAAACCCAGAGAAGATGGAAGACACAATGAATTCG
ACCCGAATAAGGATTCCAGTAGAACAGGCAATGAACGAGGAACTGCCAGGCTGTTTCCCACAGC
GAGGGCGCCATTTTACATTTCCACCAGCAGTGTATGAGGGTTCCAATTGCTCCACGTCCTCGCC
AGCACTTGTTACTGCCTGTCCTCCTTACTGTAGCCACTGTAGTGTGTGTGAAGTGGTGTCTCAT
TGTTTTGCCTTACATTTCTCTGATGGATTAATATCGTGGTGTTTATATTACTAACCTAGGGTTT
AAATCTTATACTTTGATATAGAAACCACTGTATAATACTGGATTGGTTTTTCTGAAGCAAAATC
ATAGTTCTGTATGAGATAAATGTTATTCATGAAGTTATACTTGGGAAAAAAAAACCCATAAAGT
AAAACTGACCTAGGATGAAGACAGTCACCTGAAACATCTGTCTTGCAGTATGAATCCACCCGCA
GTGTTCCTTATCTGAGCTACTAAAGTGCTATTGTGTGAATCCACCCGCAGTGTTCCTTATCTGA
GCTACTAAAGTGCTATTGTGTGACATTTACTGGATAATCCAGACAGCACTTTGACTAAAACCAC
AATATGGTGTCACTAGGTAAACACTTGGAAATGGAAATGTGTGTCTCTTCTGGTTTTATCAGTT
GAGATTAAAGGTGGTTTATAGTATAGGAAACCTTTTCTCCACACTCTGTATCTCAATGTGGGCC
AATAATCTGTCACCTGAAACTACTTAAAATAGGTTGGGCTTTCTTGACTGTCCTGTTGCTGTGA
TGACATCAGGATCTAACTGCAGAAGGGAGAAAAGGACGTTTCTCTGACTTGTTTGCCTCCTTGT
CCTTTGTCCCCAGTTAAAAGCACTGCCCTTTTCAGCCCTTACCTCTGTCTGTTTCTCAGATGTT
TTCTACATCAGTAGCATCATCTGTCACTCACCCTGTGGAGCTCCTCGTCCGGTCATAATTGTTT
CTGTCAAGGAAAGAACACCAGGTGCAGCTTGGCAGTGTGTGAGCTTCACCAGCCCTAGACAGGT
ACAGAATGAAGAAGGGGCTGGTGGAGGAGAAAACGAATCTCGAACCAAATTCAGAAGATCTTTC
TTTTTAAAAAGAGTCTCAGGATGCCTCTGAAAGCTCCCCCAGGACAGACAGCTTCACAGGAGAC
CAGTCCTCCTCTCTGGCACATAGAGAGCCTCACCTAGAGCTAAGCTTCCTGTGTGCTATGCTTT
CCTGACTGCGTCTGGCACTGTGTGCAGAAGGCCTGCAGGGGACCAAGGAGAAGAGAGAAAGAAA
GAGTAGATAGTTCTTCCCTTCCTAGTTTCTACCTCTGCCTTATCTGCCCCTCAACTTCATGTGG
GCCTGAGGCTGGGCTGGGGAGTGGTTATGAAGAATAACTAGATTGATTGGCAGATTAACTTGAA
TTCTGCCACCCCCAAAGTAATGGTAGACAACAACTTGAGACACTTGAGCTGGTGCAAGCCTTTG
TGAACTCTCTTTTGACACTTTTTTTGTTAATTGAAATACTGCTCTGGGTGAAGCAAGCACATCA
CACCTTCGAAAGCCCCTGGACAACTGGATAACCCCAGACCCTGTGCCTTCAGAACGATTGCAGA
GGAACTAGATAGTAACCATTGGTATGTTAGTAGGAACTGTGGTTTGGTCCTGACTTTTAAAATG
ACTAGCCCTCAAGTAACAGGAAAGTAAATGATGTTCACTTCCTGAATTGGACTGTGTGCTAAGA
CAGTTGAATAGCTGTGCATGGGCTCCCAGTTCATTTTTTCCACAGCCCTCTGAGATGACACAGT
TGTCCTTCAAGTGAGCTATAATGAAACTTAGTGCTTGCCTGCCATATCCAGTTTGCCCTTAGCT
CAACACCCATCTGTCTGTGACCTGATATAGTGACTGTGGTGGCTCCCCCATGTCCTATGAGGAA
TGGTGGGGAGGGGTAGGGATAGGAGCCAAGAGAGGCTGTAAAGGGCTGCATAGCAGGCTTACCC
ACATTAGAAGCCAACTGATGGGTTTGGAACTTATTTTTGGTTGGATTTTGAGTGTCCTTGCAGC
AATTTTTACAGAAAGCTTCAAGCTCCTTTCCCTCACATCCCCACAGAAGGGAATGATGGCTGAG
GAAAAGCAGATTCATTTGTTCCTGTAACAAAATAATCAAATGTGTTTCTGTGGAACAAAAACAA
ATTTGAAGTTTTGCTTGTTCTTTTCTATTATGAAATTGAAATAAAAAAGGAATGTCACCTGTA

hide sequence

RefSeq Acc Id:

XM_039078794 ⟹ XP_038934722

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	7	90,936,133 - 91,173,435 (+)	NCBI

RefSeq Acc Id:

XM_039078795 ⟹ XP_038934723

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	7	90,936,134 - 91,158,675 (+)	NCBI

RefSeq Acc Id:

XM_039078796 ⟹ XP_038934724

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	7	90,936,138 - 91,158,675 (+)	NCBI

RefSeq Acc Id:

XM_039078797 ⟹ XP_038934725

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	7	90,936,133 - 91,040,384 (+)	NCBI

RefSeq Acc Id:

XM_039078798 ⟹ XP_038934726

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	7	90,936,112 - 91,158,675 (+)	NCBI

RefSeq Acc Id:

XM_039078799 ⟹ XP_038934727

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	7	90,936,133 - 91,040,285 (+)	NCBI

RefSeq Acc Id:

XR_001838681

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	7	90,936,133 - 91,158,672 (+)	NCBI
Rnor_6.0	7	99,677,295 - 99,900,759 (+)	NCBI

Sequence:

show sequence

AGAGCGCGCGCGGGGCGTTTCAGCCACTGGAGAAGTAGGCTGAGGAAAGGAATCGGGGTCTGGG
TGTGCGACGTTCGGCAAGATATCGCTGAGCTAGGTGGGACAGCCAGATTTCAAAGATGCCAGGA
CGGTCCAGTACAAATTCAGGTTCTACTCGTTACATATCCTTCAGTGGTGTAGAGTCAGCTCTCT
CCTCCTTAAAAACCTTCCAGTCCTGTATCAGCTCTGGGATGGACACAGTTTCTAGTGTTGCCTT
GGACCTTGTGGAGACCCAAACTGAAGTGAGTAGTGAGTACAGTATGGACAAGGCCATGGTTGAA
TTTGCTAAAATGGATCGAGAACTAAACCATTATGTTAAGGCTGTCCAGTCTACAATAAATCATG
TAAAAGAAGAACGTCCAGAAAAAGTACCAGATTTAAAATTACTGGTGGAGAAGAAATTTTTGGC
TTTACAGGATAAGAACTCTGACGCCGACTTTAAAGAGAATGAAAAGTTCGTGCAGTTTAAGCAG
CAGCTGCGGGAGCTGAAGAAGCAATTAGTGAAACCCAGAGAAGATGGAAGACACAATGAATTCG
ACCCGAATAAGGATTCCAGTAGAACAGGCAATGAACGAGATGGTATTCATGCAGACAGAGAGAA
TGATGGGATAGAAGGAATGGATGAAGATATGATTGTGACCCAGAGCCAAACCAATTTCATCTGC
CCCATAACACAGTTGGAAATGAAGAAGCCAGTGAAAAATAAAATGTGTGGCCACACATACGAAG
AGGAAGCCATTGTTCGCATGATTGAATCCAAGCATAAGAGGAAGAAGAAGGCTTGGACCATGGC
TCTGTGCCTGTGAAGAGTCCTCAGTGGGCCACACTGAAGCTGACTGGGTTTGGCATCTCCTGAG
CTCTTATCGCAGGAATGGAATGGCAGTTGCCCAAAAATTGGCTGTAGCCACACAGACATGAGAA
TGTCAGATCTCATTCCGGATGAAGCCCTGAGAAGGGCAATCGAGAGCCACAACAAGAAGAAAAA
GCGCCACTCCGAGTAGGAGCCAGCCCCCTGCCCACAGGGGTGTCAGCAGCCTACCTCCCCACAG
CCACCAGAGAGTGAGCGTTCACAGCAATAGGCCCGGCAAGCTCTGCAGTGACCCTCAAGGCTAA
TTGTAATTGAAAGCATTTTTTAAGTTACACAATAAAAACACAAGTACATTATAGTCTTTATTTT
CAAGTGCTCTGAAATTTTAAATAAAACTTTGATAATCTTCA

hide sequence

RefSeq Acc Id:

XR_005486582

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	7	90,936,133 - 91,158,463 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001020047	(Get FASTA)	NCBI Sequence Viewer
	XP_006241733	(Get FASTA)	NCBI Sequence Viewer
	XP_017450247	(Get FASTA)	NCBI Sequence Viewer
	XP_017450249	(Get FASTA)	NCBI Sequence Viewer
	XP_038934722	(Get FASTA)	NCBI Sequence Viewer
	XP_038934723	(Get FASTA)	NCBI Sequence Viewer
	XP_038934724	(Get FASTA)	NCBI Sequence Viewer
	XP_038934725	(Get FASTA)	NCBI Sequence Viewer
	XP_038934726	(Get FASTA)	NCBI Sequence Viewer
	XP_038934727	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH97477	(Get FASTA)	NCBI Sequence Viewer
	EDM16198	(Get FASTA)	NCBI Sequence Viewer
	EDM16199	(Get FASTA)	NCBI Sequence Viewer
	EDM16200	(Get FASTA)	NCBI Sequence Viewer
	Q4V8A0	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001020047 ⟸ NM_001024876

- UniProtKB:

Q4V8A0 (UniProtKB/Swiss-Prot), A6HRM3 (UniProtKB/TrEMBL), A0A0G2JW49 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MPGRSSTNSGSTRYISFSGVESALSSLKTFQSCISSGMDTVSSVALDLVETQTEVSSEYSMDKA
MVEFAKMDRELNHYVKAVQSTINHVKEERPEKVPDLKLLVEKKFLALQDKNSDADFKENEKFVQ
FKQQLRELKKQYGIHADRENDGIEGMDEDMIVTQSQTNFICPITQLEMKKPVKNKMCGHTYEEE
AIVRMIESKHKRKKKACCPKIGCSHTDMRMSDLIPDEALRRAIESHNKKKKRHSE

hide sequence

RefSeq Acc Id:	XP_006241733 ⟸ XM_006241671
- Peptide Label:	isoform X9
- UniProtKB:	A0A8I6AS08 (UniProtKB/TrEMBL)
- Sequence:	show sequence MPGRSSTNSGSTRYISFSGVESALSSLKTFQSCISSGMDTVSSVALDLVETQTEVSSEYSMDKA MVEFAKMDRELNHYVKAVQSTINHVKEERPEKVPDLKLLVEKKFLALQDKNSDADFKENEKFVQ FKQQLRELKKQ hide sequence

RefSeq Acc Id:	XP_017450247 ⟸ XM_017594758
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I6A069 (UniProtKB/TrEMBL), A6HRM2 (UniProtKB/TrEMBL)
- Sequence:	show sequence MPGRSSTNSGSTRYISFSGVESALSSLKTFQSCISSGMDTVSSVALDLVETQTEVSSEYSMDKA MVEFAKMDRELNHYVKAVQSTINHVKEERPEKVPDLKLLVEKKFLALQDKNSDADFKENEKFVQ FKQQLRELKKQLVKPREDGRHNEFDPNKDSSRTGNERDGIHADRENDGIEGMDEDMIVTQSQTN FICPITQLEMKKPVKNKMCGHTYEEEAIVRMIESKHKRKKKACCPKIGCSHTDMRMSDLIPDEA LRRAIESHNKKKKRHSE hide sequence

RefSeq Acc Id:	XP_017450249 ⟸ XM_017594760
- Peptide Label:	isoform X5
- Sequence:	show sequence MPGRSSTNSGSTRYISFSGVESALSSLKTFQSCISSGMDTVSSVALDLVETQTEVSSEYSMDKA MVEFAKMDRELNHYVKAVQSTINHVKEERPEKVPDLKLLVEKKFLALQDKNSDADFKENEKFVQ FKQQLRELKKQLVKPREDGRHNEFDPNKDSSRTGNERGTARLFPTARAPFYISTSSV hide sequence

RefSeq Acc Id:

ENSRNOP00000005376 ⟸ ENSRNOT00000005376

RefSeq Acc Id:

ENSRNOP00000069742 ⟸ ENSRNOT00000086039

RefSeq Acc Id:	XP_038934726 ⟸ XM_039078798
- Peptide Label:	isoform X7
- UniProtKB:	A6HRM4 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038934722 ⟸ XM_039078794
- Peptide Label:	isoform X2
- UniProtKB:	A0A0G2JW49 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038934725 ⟸ XM_039078797
- Peptide Label:	isoform X6

RefSeq Acc Id:	XP_038934727 ⟸ XM_039078799
- Peptide Label:	isoform X8

RefSeq Acc Id:	XP_038934723 ⟸ XM_039078795
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_038934724 ⟸ XM_039078796
- Peptide Label:	isoform X4

RefSeq Acc Id:

ENSRNOP00000097544 ⟸ ENSRNOT00000102133

RefSeq Acc Id:

ENSRNOP00000085874 ⟸ ENSRNOT00000099968

Protein Domains

SP-RING-type

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q4V8A0-F1-model_v2	AlphaFold	Q4V8A0	1-247	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1305156	AgrOrtholog
BioCyc Gene	G2FUF-33289	BioCyc
Ensembl Genes	ENSRNOG00000003964	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000005376	ENTREZGENE, UniProtKB/Swiss-Prot
	ENSRNOP00000069742	ENTREZGENE
	ENSRNOP00000069742.2	UniProtKB/TrEMBL
	ENSRNOP00000085874	ENTREZGENE
	ENSRNOP00000085874.1	UniProtKB/TrEMBL
	ENSRNOP00000097544	ENTREZGENE
	ENSRNOP00000097544.1	UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000005376	ENTREZGENE, UniProtKB/Swiss-Prot
	ENSRNOT00000086039	ENTREZGENE
	ENSRNOT00000086039.2	UniProtKB/TrEMBL
	ENSRNOT00000099968	ENTREZGENE
	ENSRNOT00000099968.1	UniProtKB/TrEMBL
	ENSRNOT00000102133	ENTREZGENE
	ENSRNOT00000102133.1	UniProtKB/TrEMBL
Gene3D-CATH	3.30.40.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7458086	IMAGE-MGC_LOAD
InterPro	Nse2(Mms21)	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Ubox_domain	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Znf_MIZ	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Znf_RING/FYVE/PHD	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:299957	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:114542	IMAGE-MGC_LOAD
NCBI Gene	299957	ENTREZGENE
PANTHER	E3 SUMO-PROTEIN LIGASE NSE2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PTHR21330	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	zf-Nse	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Nsmce2	PhenoGen
PROSITE	ZF_SP_RING	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART	Ubox	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	RING/U-box	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A0G2JW49	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6A069	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6AS08	ENTREZGENE, UniProtKB/TrEMBL
	A6HRM2	ENTREZGENE, UniProtKB/TrEMBL
	A6HRM3	ENTREZGENE, UniProtKB/TrEMBL
	A6HRM4	ENTREZGENE, UniProtKB/TrEMBL
	NSE2_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2015-08-13	Nsmce2	NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase	Nsmce2	non-SMC element 2, MMS21 homolog (S. cerevisiae)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-03-06	Nsmce2	non-SMC element 2, MMS21 homolog (S. cerevisiae)	RGD1305156	similar to RIKEN cDNA 1110014D18	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-12-06	RGD1305156	similar to RIKEN cDNA 1110014D18	RGD1305156_predicted	similar to RIKEN cDNA 1110014D18 (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-20	RGD1305156_predicted	similar to RIKEN cDNA 1110014D18 (predicted)	LOC299957_predicted		Symbol and Name status set to approved	1331353	APPROVED
2005-01-12	LOC299957_predicted	similar to RIKEN cDNA 1110014D18 (predicted)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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