Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Txnl4b | Rat | (+)-schisandrin B | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of TXNL4B mRNA] | CTD | PMID:31150632 | Txnl4b | Rat | (-)-epigallocatechin 3-gallate | multiple interactions | ISO | TXNL4B (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of TXNL4B mRNA | CTD | PMID:22079256 | Txnl4b | Rat | 1,2-dichloroethane | decreases expression | ISO | Txnl4b (Mus musculus) | 6480464 | ethylene dichloride results in decreased expression of TXNL4B mRNA | CTD | PMID:28960355 | Txnl4b | Rat | 1,2-dimethylhydrazine | increases expression | ISO | Txnl4b (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in increased expression of TXNL4B mRNA | CTD | PMID:22206623 | Txnl4b | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Txnl4b (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of TXNL4B mRNA | CTD | PMID:21570461 | Txnl4b | Rat | 2,4-dinitrotoluene | affects expression | EXP | | 6480464 | 2 and 4-dinitrotoluene affects the expression of TXNL4B mRNA | CTD | PMID:21346803 | Txnl4b | Rat | 3,4-methylenedioxymethamphetamine | decreases methylation | ISO | Txnl4b (Mus musculus) | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased methylation of TXNL4B promoter | CTD | PMID:26251327 | Txnl4b | Rat | 3,4-methylenedioxymethamphetamine | decreases expression | ISO | Txnl4b (Mus musculus) | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased expression of TXNL4B mRNA | CTD | PMID:26251327 | Txnl4b | Rat | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of TXNL4B mRNA | CTD | PMID:30047161 | Txnl4b | Rat | acrolein | multiple interactions | ISO | TXNL4B (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of TXNL4B mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of TXNL4B mRNA | CTD | PMID:32699268 | Txnl4b | Rat | acrylamide | increases expression | ISO | TXNL4B (Homo sapiens) | 6480464 | Acrylamide results in increased expression of TXNL4B mRNA | CTD | PMID:32763439 | Txnl4b | Rat | aflatoxin B1 | decreases methylation | ISO | TXNL4B (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of TXNL4B gene | CTD | PMID:27153756 | Txnl4b | Rat | alpha-pinene | multiple interactions | ISO | TXNL4B (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of TXNL4B mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of TXNL4B mRNA | CTD | PMID:32699268 | Txnl4b | Rat | amitrole | decreases expression | EXP | | 6480464 | Amitrole results in decreased expression of TXNL4B mRNA | CTD | PMID:30047161 | Txnl4b | Rat | antirheumatic drug | decreases expression | ISO | TXNL4B (Homo sapiens) | 6480464 | Antirheumatic Agents results in decreased expression of TXNL4B mRNA | CTD | PMID:24449571 | Txnl4b | Rat | aristolochic acid A | increases expression | ISO | TXNL4B (Homo sapiens) | 6480464 | aristolochic acid I results in increased expression of TXNL4B mRNA and aristolochic acid I results in increased expression of TXNL4B protein | CTD | PMID:33212167 | Txnl4b | Rat | benzophenone | increases expression | EXP | | 6480464 | benzophenone results in increased expression of TXNL4B mRNA | CTD | PMID:22584684 | Txnl4b | Rat | bisphenol A | affects expression | ISO | TXNL4B (Homo sapiens) | 6480464 | bisphenol A affects the expression of TXNL4B mRNA | CTD | PMID:22574217 | Txnl4b | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of TXNL4B mRNA | CTD | PMID:34947998 | Txnl4b | Rat | bisphenol A | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with Genistein] results in increased methylation of TXNL4B gene | CTD | PMID:28505145 | Txnl4b | Rat | bisphenol A | increases methylation | ISO | Txnl4b (Mus musculus) | 6480464 | bisphenol A results in increased methylation of TXNL4B promoter | CTD | PMID:27312807 | Txnl4b | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of TXNL4B mRNA | CTD | PMID:25181051 | Txnl4b | Rat | cadmium dichloride | decreases expression | ISO | TXNL4B (Homo sapiens) | 6480464 | Cadmium Chloride results in decreased expression of TXNL4B mRNA | CTD | PMID:38568856 | Txnl4b | Rat | carbon nanotube | decreases expression | ISO | Txnl4b (Mus musculus) | 6480464 | Nanotubes more ... | CTD | PMID:25620056 | Txnl4b | Rat | CGP 52608 | multiple interactions | ISO | TXNL4B (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to TXNL4B gene] | CTD | PMID:28238834 | Txnl4b | Rat | cisplatin | multiple interactions | ISO | TXNL4B (Homo sapiens) | 6480464 | Cisplatin promotes the reaction [jinfukang results in decreased expression of TXNL4B mRNA] and jinfukang promotes the reaction [Cisplatin results in decreased expression of TXNL4B mRNA] | CTD | PMID:27392435 | Txnl4b | Rat | cyclosporin A | increases methylation | ISO | TXNL4B (Homo sapiens) | 6480464 | Cyclosporine results in increased methylation of TXNL4B promoter | CTD | PMID:27989131 | Txnl4b | Rat | cypermethrin | increases expression | ISO | TXNL4B (Homo sapiens) | 6480464 | cypermethrin results in increased expression of TXNL4B mRNA | CTD | PMID:27704156 | Txnl4b | Rat | Dibutyl phosphate | affects expression | ISO | TXNL4B (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of TXNL4B mRNA | CTD | PMID:37042841 | Txnl4b | Rat | dorsomorphin | multiple interactions | ISO | TXNL4B (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TXNL4B mRNA | CTD | PMID:27188386 | Txnl4b | Rat | doxorubicin | decreases expression | ISO | TXNL4B (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of TXNL4B mRNA | CTD | PMID:29803840 | Txnl4b | Rat | emodin | decreases expression | ISO | TXNL4B (Homo sapiens) | 6480464 | Emodin results in decreased expression of TXNL4B mRNA | CTD | PMID:16045814 | Txnl4b | Rat | endosulfan | increases expression | EXP | | 6480464 | Endosulfan results in increased expression of TXNL4B mRNA | CTD | PMID:29391264 | Txnl4b | Rat | ethyl methanesulfonate | increases expression | ISO | TXNL4B (Homo sapiens) | 6480464 | Ethyl Methanesulfonate results in increased expression of TXNL4B mRNA | CTD | PMID:23649840 | Txnl4b | Rat | fenthion | decreases expression | ISO | Txnl4b (Mus musculus) | 6480464 | Fenthion results in decreased expression of TXNL4B mRNA | CTD | PMID:34813904 | Txnl4b | Rat | flutamide | increases expression | EXP | | 6480464 | Flutamide results in increased expression of TXNL4B mRNA | CTD | PMID:24793618 | Txnl4b | Rat | formaldehyde | increases expression | ISO | TXNL4B (Homo sapiens) | 6480464 | Formaldehyde results in increased expression of TXNL4B mRNA | CTD | PMID:23649840 | Txnl4b | Rat | furan | decreases methylation | EXP | | 6480464 | furan results in decreased methylation of TXNL4B gene | CTD | PMID:22079235 | Txnl4b | Rat | genistein | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with Genistein] results in increased methylation of TXNL4B gene | CTD | PMID:28505145 | Txnl4b | Rat | glyphosate | decreases expression | ISO | Txnl4b (Mus musculus) | 6480464 | Glyphosate results in decreased expression of TXNL4B mRNA | CTD | PMID:35897073 | Txnl4b | Rat | leflunomide | decreases expression | ISO | TXNL4B (Homo sapiens) | 6480464 | leflunomide results in decreased expression of TXNL4B mRNA | CTD | PMID:28988120 | Txnl4b | Rat | methapyrilene | increases expression | EXP | | 6480464 | Methapyrilene results in increased expression of TXNL4B mRNA | CTD | PMID:22584684 | Txnl4b | Rat | methidathion | decreases expression | ISO | Txnl4b (Mus musculus) | 6480464 | methidathion results in decreased expression of TXNL4B mRNA | CTD | PMID:34813904 | Txnl4b | Rat | methimazole | decreases expression | EXP | | 6480464 | Methimazole results in decreased expression of TXNL4B mRNA | CTD | PMID:30047161 | Txnl4b | Rat | methyl methanesulfonate | increases expression | ISO | TXNL4B (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in increased expression of TXNL4B mRNA | CTD | PMID:23649840 | Txnl4b | Rat | methylisothiazolinone | increases expression | ISO | TXNL4B (Homo sapiens) | 6480464 | 2-methyl-4-isothiazolin-3-one results in increased expression of TXNL4B mRNA | CTD | PMID:31629900 | Txnl4b | Rat | methylmercury chloride | increases expression | ISO | TXNL4B (Homo sapiens) | 6480464 | methylmercuric chloride results in increased expression of TXNL4B mRNA | CTD | PMID:28001369 | Txnl4b | Rat | monuron | increases expression | EXP | | 6480464 | monuron results in increased expression of TXNL4B mRNA | CTD | PMID:22584684 | Txnl4b | Rat | nickel atom | increases expression | ISO | TXNL4B (Homo sapiens) | 6480464 | Nickel results in increased expression of TXNL4B mRNA | CTD | PMID:24768652 and PMID:25583101 | Txnl4b | Rat | ozone | multiple interactions | ISO | TXNL4B (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of TXNL4B mRNA more ... | CTD | PMID:32699268 | Txnl4b | Rat | paracetamol | increases expression | ISO | TXNL4B (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of TXNL4B mRNA | CTD | PMID:26690555 | Txnl4b | Rat | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of TXNL4B mRNA | CTD | PMID:33387578 | Txnl4b | Rat | picoxystrobin | decreases expression | ISO | TXNL4B (Homo sapiens) | 6480464 | picoxystrobin results in decreased expression of TXNL4B mRNA | CTD | PMID:33512557 | Txnl4b | Rat | potassium chromate | increases expression | ISO | TXNL4B (Homo sapiens) | 6480464 | potassium chromate(VI) results in increased expression of TXNL4B mRNA | CTD | PMID:22079256 | Txnl4b | Rat | potassium chromate | multiple interactions | ISO | TXNL4B (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of TXNL4B mRNA | CTD | PMID:22079256 | Txnl4b | Rat | rotenone | decreases expression | ISO | TXNL4B (Homo sapiens) | 6480464 | Rotenone results in decreased expression of TXNL4B mRNA | CTD | PMID:29955902 and PMID:33512557 | Txnl4b | Rat | SB 431542 | multiple interactions | ISO | TXNL4B (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TXNL4B mRNA | CTD | PMID:27188386 | Txnl4b | Rat | sodium arsenite | increases expression | ISO | TXNL4B (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of TXNL4B mRNA | CTD | PMID:38568856 | Txnl4b | Rat | sulfadimethoxine | decreases expression | EXP | | 6480464 | Sulfadimethoxine results in decreased expression of TXNL4B mRNA | CTD | PMID:30047161 | Txnl4b | Rat | T-2 toxin | increases expression | ISO | TXNL4B (Homo sapiens) | 6480464 | T-2 Toxin results in increased expression of TXNL4B mRNA | CTD | PMID:34581912 | Txnl4b | Rat | tetrachloromethane | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of TXNL4B mRNA] | CTD | PMID:31150632 | Txnl4b | Rat | tetrachloromethane | increases expression | EXP | | 6480464 | Carbon Tetrachloride results in increased expression of TXNL4B mRNA | CTD | PMID:31150632 | Txnl4b | Rat | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of TXNL4B mRNA | CTD | PMID:34492290 | Txnl4b | Rat | thiram | increases expression | ISO | TXNL4B (Homo sapiens) | 6480464 | Thiram results in increased expression of TXNL4B mRNA | CTD | PMID:38568856 | Txnl4b | Rat | trichloroethene | increases methylation | EXP | | 6480464 | Trichloroethylene results in increased methylation of TXNL4B gene | CTD | PMID:27618143 | Txnl4b | Rat | urethane | increases expression | ISO | TXNL4B (Homo sapiens) | 6480464 | Urethane results in increased expression of TXNL4B mRNA | CTD | PMID:28818685 | Txnl4b | Rat | valproic acid | affects expression | ISO | TXNL4B (Homo sapiens) | 6480464 | Valproic Acid affects the expression of TXNL4B mRNA | CTD | PMID:25979313 | Txnl4b | Rat | valproic acid | increases expression | ISO | TXNL4B (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of TXNL4B mRNA | CTD | PMID:23179753 and PMID:26272509 | Txnl4b | Rat | valproic acid | multiple interactions | ISO | TXNL4B (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TXNL4B mRNA | CTD | PMID:27188386 | |