Predicted to enable GTPase activator activity and catalytic activity, acting on a tRNA. Predicted to be involved in several processes, including cellular response to L-leucine; cellular response to leucine starvation; and tRNA aminoacylation for protein translation. Predicted to be located in several cellular components, including endoplasmic reticulum; lysosome; and nuclear body. Predicted to be part of aminoacyl-tRNA synthetase multienzyme complex. Human ortholog(s) of this gene implicated in infantile liver failure syndrome 1. Orthologous to human LARS1 (leucyl-tRNA synthetase 1); PARTICIPATES IN aminoacyl-tRNA biosynthetic pathway; valine, leucine and isoleucine biosynthetic pathway; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene.
2-bromopalmitate inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased palmitoylation of LARS1 protein]
2-bromopalmitate inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased palmitoylation of LARS1 protein] and [Cadmium Chloride results in increased abundance of Cadmium] which results in increased palmitoylation of LARS1 protein
2-bromopalmitate inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased palmitoylation of LARS1 protein] and [Cadmium Chloride results in increased abundance of Cadmium] which results in increased palmitoylation of LARS1 protein
[Sodium Chloride co-treated with Furaldehyde] results in decreased expression of LARS1 protein and [Sodium Chloride co-treated with Furaldehyde] results in increased expression of and affects the localization of LARS1 protein
[NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of LARS1 mRNA
[NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of LARS1 mRNA