Rc3h2 (ring finger and CCCH-type domains 2) - Rat Genome Database

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Gene: Rc3h2 (ring finger and CCCH-type domains 2) Rattus norvegicus
Analyze
Symbol: Rc3h2
Name: ring finger and CCCH-type domains 2
RGD ID: 1304833
Description: Predicted to enable nucleic acid binding activity and ubiquitin protein ligase activity. Predicted to be involved in several processes, including T cell receptor signaling pathway; negative regulation of T-helper 17 cell differentiation; and regulation of RNA metabolic process. Predicted to act upstream of or within several processes, including T cell activation; hematopoietic or lymphoid organ development; and lymphocyte homeostasis. Predicted to be located in cell surface; intracellular membrane-bounded organelle; and membrane. Predicted to be active in cytoplasmic stress granule. Orthologous to human RC3H2 (ring finger and CCCH-type domains 2); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC311909; membrane associated DNA binding protein; Mnab; RING finger and CCCH-type zinc finger domain-containing protein 2; ring finger and CCCH-type zinc finger domains 2; roquin-2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8341,531,319 - 41,596,496 (-)NCBIGRCr8
mRatBN7.2321,121,531 - 21,186,711 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl321,110,679 - 21,179,933 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx324,605,042 - 24,654,968 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0333,190,004 - 33,239,931 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0331,000,791 - 31,050,737 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0321,621,976 - 21,676,789 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl321,623,041 - 21,670,014 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0326,852,132 - 26,915,899 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4317,133,485 - 17,183,391 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1317,029,857 - 17,079,811 (-)NCBI
Celera319,572,305 - 19,622,174 (-)NCBICelera
Cytogenetic Map3q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. GOA pipeline RGD automated data pipeline
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10938276   PMID:22658674   PMID:22681889   PMID:23583643   PMID:24448648   PMID:25282160   PMID:25697406   PMID:26249698   PMID:26489670  


Genomics

Comparative Map Data
Rc3h2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8341,531,319 - 41,596,496 (-)NCBIGRCr8
mRatBN7.2321,121,531 - 21,186,711 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl321,110,679 - 21,179,933 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx324,605,042 - 24,654,968 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0333,190,004 - 33,239,931 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0331,000,791 - 31,050,737 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0321,621,976 - 21,676,789 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl321,623,041 - 21,670,014 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0326,852,132 - 26,915,899 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4317,133,485 - 17,183,391 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1317,029,857 - 17,079,811 (-)NCBI
Celera319,572,305 - 19,622,174 (-)NCBICelera
Cytogenetic Map3q11NCBI
RC3H2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389122,844,556 - 122,905,359 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9122,844,556 - 122,905,359 (-)EnsemblGRCh38hg38GRCh38
GRCh379125,606,835 - 125,667,638 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 369124,651,553 - 124,707,383 (-)NCBINCBI36Build 36hg18NCBI36
Build 349122,695,629 - 122,734,765NCBI
Celera996,260,078 - 96,315,869 (-)NCBICelera
Cytogenetic Map9q33.2NCBI
HuRef995,226,328 - 95,282,388 (-)NCBIHuRef
CHM1_19125,759,577 - 125,816,220 (-)NCBICHM1_1
T2T-CHM13v2.09135,041,909 - 135,102,585 (-)NCBIT2T-CHM13v2.0
Rc3h2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39237,260,078 - 37,313,007 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl237,260,081 - 37,312,915 (-)EnsemblGRCm39 Ensembl
GRCm38237,368,861 - 37,424,370 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl237,370,069 - 37,422,903 (-)EnsemblGRCm38mm10GRCm38
MGSCv37237,225,589 - 37,278,423 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36237,190,904 - 37,244,912 (-)NCBIMGSCv36mm8
Celera237,054,071 - 37,106,912 (-)NCBICelera
Cytogenetic Map2BNCBI
cM Map224.19NCBI
Rc3h2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554195,054,289 - 5,103,926 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554195,054,288 - 5,103,926 (+)NCBIChiLan1.0ChiLan1.0
RC3H2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21116,445,874 - 16,502,261 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1916,448,222 - 16,504,609 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0993,975,164 - 94,031,516 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19122,308,725 - 122,365,106 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9122,313,791 - 122,365,102 (-)Ensemblpanpan1.1panPan2
RC3H2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1959,881,889 - 59,943,271 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl959,881,966 - 59,929,341 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha959,076,857 - 59,138,347 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0960,801,185 - 60,862,372 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl960,801,013 - 60,849,592 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1959,559,803 - 59,621,280 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0959,874,804 - 59,936,355 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0959,967,554 - 60,029,349 (+)NCBIUU_Cfam_GSD_1.0
Rc3h2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947191,568,045 - 191,624,687 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648711,341,700 - 11,389,859 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648711,341,663 - 11,393,275 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RC3H2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1263,772,173 - 263,822,104 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11263,769,403 - 263,822,101 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21297,236,916 - 297,279,474 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RC3H2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11215,230,206 - 15,283,253 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1215,238,124 - 15,280,689 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666079781,952 - 837,969 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rc3h2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462476012,025,206 - 12,074,548 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Rc3h2
179 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:148
Count of miRNA genes:112
Interacting mature miRNAs:118
Transcripts:ENSRNOT00000012354
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70202Alc19Alcohol consumption QTL 192.5drinking behavior trait (VT:0001422)ethanol intake volume to total fluid intake volume ratio (CMO:0001591)3127494778Rat
631679Cm10Cardiac mass QTL 107.340.0001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)3131158234Rat
631831Alc8Alcohol consumption QTL 82.7consumption behavior trait (VT:0002069)calculated ethanol drink intake rate (CMO:0001615)3133230976Rat
61468Bp15Blood pressure QTL 154.4blood pressure trait (VT:0000183)diastolic blood pressure (CMO:0000005)3133278763Rat
61468Bp15Blood pressure QTL 154.4blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)3133278763Rat
61468Bp15Blood pressure QTL 154.4blood pressure trait (VT:0000183)pulse pressure (CMO:0000292)3133278763Rat
631545Bp85Blood pressure QTL 853.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3133278763Rat
4889966Bss95Bone structure and strength QTL 954.4tibia area (VT:1000281)tibia-fibula cross-sectional area (CMO:0001718)3136847613Rat
2312664Scl62Serum cholesterol level QTL 620.05blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)3138710544Rat
631568Bp92Blood pressure QTL 922.20.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3139874793Rat
2290452Scl56Serum cholesterol level QTL 562.26blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)3191609953Rat
1298526Arunc3Aerobic running capacity QTL 32.2exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)3822719433703538Rat
10401810Kidm53Kidney mass QTL 53kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)3822719447233430Rat
70203Gcr2Gastric cancer resistance QTL 22.6stomach morphology trait (VT:0000470)stomach tumor susceptibility score (CMO:0002043)3865816227494778Rat
1358357Srcrtb1Stress Responsive Cort Basal QTL 16.360.002blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)3865816227494778Rat
6893355Bw101Body weight QTL 1010.40.38body mass (VT:0001259)body weight (CMO:0000012)31077870430357018Rat
6893363Bw105Body weight QTL 1052.60.0036body mass (VT:0001259)body weight (CMO:0000012)31077870430357018Rat
1558654Bw56Body weight QTL 564.50.0000171body mass (VT:0001259)body weight (CMO:0000012)31077870430357018Rat
70191BpQTLcluster4Blood pressure QTL cluster 43arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)31077870450302886Rat
70191BpQTLcluster4Blood pressure QTL cluster 43arterial blood pressure trait (VT:2000000)absolute change in systolic blood pressure (CMO:0000607)31077870450302886Rat
1558647Cm46Cardiac mass QTL 465.40.0000055heart mass (VT:0007028)heart wet weight (CMO:0000069)31077882330356773Rat
1558650Cm48Cardiac mass QTL 4840.0001heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)31077882330356773Rat
1558657Cm43Cardiac mass QTL 436.60.0000000293heart mass (VT:0007028)heart wet weight (CMO:0000069)31077882330356773Rat
1358905Hrtrt17Heart rate QTL 175.90.000014heart pumping trait (VT:2000009)heart rate (CMO:0000002)31086191289878372Rat
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
2298542Neuinf11Neuroinflammation QTL 113.9nervous system integrity trait (VT:0010566)spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)31500542276927699Rat
631676Cm8Cardiac mass QTL 87.030.0001aorta mass (VT:0002845)aorta weight (CMO:0000076)31695470861954708Rat
634306Bp140Blood pressure QTL 1403.30.0013arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)31737470335528639Rat
634306Bp140Blood pressure QTL 1403.30.0013arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)31737470335528639Rat
634306Bp140Blood pressure QTL 1403.30.0013arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)31737470335528639Rat
634306Bp140Blood pressure QTL 1403.30.0013arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)31737470335528639Rat
634306Bp140Blood pressure QTL 1403.30.0013arterial blood pressure trait (VT:2000000)heart rate (CMO:0000002)31737470335528639Rat
634306Bp140Blood pressure QTL 1403.30.0013arterial blood pressure trait (VT:2000000)heart rate (CMO:0000002)31737470335528639Rat
634306Bp140Blood pressure QTL 1403.30.0013arterial blood pressure trait (VT:2000000)body weight (CMO:0000012)31737470335528639Rat
634306Bp140Blood pressure QTL 1403.30.0013arterial blood pressure trait (VT:2000000)body weight (CMO:0000012)31737470335528639Rat
2325840Bp345Blood pressure QTL 3450.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)31831145428441896Rat
731172Bp151Blood pressure QTL 1510.04arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)31831145447233430Rat
12879849Bw180Body weight QTL 1800.037body mass (VT:0001259)body weight (CMO:0000012)31831145447233430Rat
12879850Cm91Cardiac mass QTL 910.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)31831145447233430Rat
12879851Cm92Cardiac mass QTL 920.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)31831145447233430Rat
12879852Cm93Cardiac mass QTL 930.001heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)31831145447233430Rat
12879853Am5Aortic mass QTL 50.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)31831145447233430Rat
12879854Kidm63Kidney mass QTL 630.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)31831145447233430Rat
10450804Scl70Serum cholesterol level QTL 704.70.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)32071409065714090Rat
10450794Scl69Serum cholesterol level QTL 696.30.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)32071409065714090Rat

Markers in Region
D3Got13  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2321,188,418 - 21,188,642 (+)MAPPERmRatBN7.2
Rnor_6.0321,678,440 - 21,678,663NCBIRnor6.0
Rnor_5.0326,917,615 - 26,917,838UniSTSRnor5.0
RGSC_v3.4317,185,160 - 17,185,484RGDRGSC3.4
RGSC_v3.4317,185,218 - 17,185,441UniSTSRGSC3.4
RGSC_v3.1317,081,590 - 17,081,813RGD
Celera319,623,986 - 19,624,209UniSTS
RH 3.4 Map3197.5RGD
RH 3.4 Map3197.5UniSTS
Cytogenetic Map3q11UniSTS
BE108864  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2321,169,390 - 21,169,540 (+)MAPPERmRatBN7.2
Rnor_6.0321,659,489 - 21,659,638NCBIRnor6.0
Rnor_5.0326,898,709 - 26,898,858UniSTSRnor5.0
RGSC_v3.4317,166,123 - 17,166,272UniSTSRGSC3.4
Celera319,604,936 - 19,605,085UniSTS
RH 3.4 Map3205.3UniSTS
Cytogenetic Map3q11UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 34 28 12 19 12 8 10 74 30 39 11 8
Low 1 9 29 29 29 1 5 2
Below cutoff

Sequence


RefSeq Acc Id: ENSRNOT00000012354   ⟹   ENSRNOP00000012354
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl321,132,188 - 21,179,933 (-)Ensembl
Rnor_6.0 Ensembl321,626,852 - 21,669,957 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000078718   ⟹   ENSRNOP00000075040
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl321,110,679 - 21,179,933 (-)Ensembl
Rnor_6.0 Ensembl321,623,041 - 21,670,014 (-)Ensembl
RefSeq Acc Id: NM_001107839   ⟹   NP_001101309
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8341,546,537 - 41,596,443 (-)NCBI
mRatBN7.2321,136,749 - 21,186,661 (-)NCBI
Rnor_6.0321,626,852 - 21,676,679 (-)NCBI
Rnor_5.0326,852,132 - 26,915,899 (-)NCBI
RGSC_v3.4317,133,485 - 17,183,391 (-)RGD
Celera319,572,305 - 19,622,174 (-)RGD
Sequence:
RefSeq Acc Id: XM_008761754   ⟹   XP_008759976
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8341,541,661 - 41,596,496 (-)NCBI
mRatBN7.2321,136,942 - 21,186,711 (-)NCBI
Rnor_6.0321,627,092 - 21,676,789 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039105269   ⟹   XP_038961197
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8341,531,319 - 41,596,496 (-)NCBI
mRatBN7.2321,121,531 - 21,186,711 (-)NCBI
RefSeq Acc Id: XR_005501919
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8341,541,661 - 41,596,496 (-)NCBI
mRatBN7.2321,131,873 - 21,186,711 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001101309 (Get FASTA)   NCBI Sequence Viewer  
  XP_008759976 (Get FASTA)   NCBI Sequence Viewer  
  XP_038961197 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDM00530 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000012354
  ENSRNOP00000012354.6
  ENSRNOP00000075040
  ENSRNOP00000075040.2
RefSeq Acc Id: NP_001101309   ⟸   NM_001107839
- UniProtKB: A6JET0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008759976   ⟸   XM_008761754
- Peptide Label: isoform X2
- UniProtKB: D3ZBM2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000012354   ⟸   ENSRNOT00000012354
RefSeq Acc Id: ENSRNOP00000075040   ⟸   ENSRNOT00000078718
RefSeq Acc Id: XP_038961197   ⟸   XM_039105269
- Peptide Label: isoform X1
- UniProtKB: A0A0G2K9L3 (UniProtKB/TrEMBL)
Protein Domains
C3H1-type   RING-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZBM2-F1-model_v2 AlphaFold D3ZBM2 1-1187 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1304833 AgrOrtholog
BioCyc Gene G2FUF-49941 BioCyc
Ensembl Genes ENSRNOG00000009196 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000012354.7 UniProtKB/TrEMBL
  ENSRNOT00000078718.2 UniProtKB/TrEMBL
Gene3D-CATH 1.20.120.1790 UniProtKB/TrEMBL
  3.30.40.10 UniProtKB/TrEMBL
  Zinc finger, CCCH-type UniProtKB/TrEMBL
InterPro ROQ_II UniProtKB/TrEMBL
  Roquin_1_2-like_ROQ UniProtKB/TrEMBL
  Znf_CCCH UniProtKB/TrEMBL
  Znf_CCCH_sf UniProtKB/TrEMBL
  Znf_RING UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
  Znf_RING_CS UniProtKB/TrEMBL
KEGG Report rno:311909 UniProtKB/TrEMBL
NCBI Gene 311909 ENTREZGENE
PANTHER PTHR13139:SF2 UniProtKB/TrEMBL
  RING FINGER AND CCCH-TYPE ZINC FINGER DOMAIN-CONTAINING PROTEIN UniProtKB/TrEMBL
Pfam ROQ_II UniProtKB/TrEMBL
  Roquin_1_2-like_ROQ UniProtKB/TrEMBL
  zf-CCCH UniProtKB/TrEMBL
  zf-RING_5 UniProtKB/TrEMBL
PhenoGen Rc3h2 PhenoGen
PROSITE ZF_C3H1 UniProtKB/TrEMBL
  ZF_RING_1 UniProtKB/TrEMBL
  ZF_RING_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000009196 RatGTEx
SMART RING UniProtKB/TrEMBL
  ZnF_C3H1 UniProtKB/TrEMBL
Superfamily-SCOP RING/U-box UniProtKB/TrEMBL
  SSF90229 UniProtKB/TrEMBL
UniProt A0A0G2K9L3 ENTREZGENE, UniProtKB/TrEMBL
  A6JET0 ENTREZGENE, UniProtKB/TrEMBL
  D3ZBM2 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-08-02 Rc3h2  ring finger and CCCH-type domains 2  Rc3h2  ring finger and CCCH-type zinc finger domains 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-06 Rc3h2  ring finger and CCCH-type zinc finger domains 2  Mnab_predicted  membrane associated DNA binding protein (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-12 Mnab_predicted  membrane associated DNA binding protein (predicted)      Symbol and Name status set to approved 70820 APPROVED