Gene: Rprd1b (regulation of nuclear pre-mRNA domain containing 1B) Rattus norvegicus
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Symbol:
Rprd1b
Name:
regulation of nuclear pre-mRNA domain containing 1B
RGD ID:
1304782
Description:
Predicted to enable RNA polymerase II complex binding activity and identical protein binding activity. Predicted to be involved in several processes, including RNA metabolic process; positive regulation of cell population proliferation; and positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleoplasm. Predicted to be part of transcription preinitiation complex. Orthologous to human RPRD1B (regulation of nuclear pre-mRNA domain containing 1B); INTERACTS WITH 1,2-dimethylhydrazine; bisphenol A; trichloroethene.
Type:
protein-coding
RefSeq Status:
VALIDATED
Previously known as:
cell-cycle related and expression-elevated protein in tumor; Crept; LOC311591; regulation of nuclear pre-mRNA domain-containing protein 1B; RGD1304782; similar to RIKEN cDNA 2610304G08 gene
RGD Orthologs
Alliance Orthologs
More Info
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More Info
Latest Assembly:
GRCr8 - GRCr8 Assembly
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 3 167,102,909 - 167,149,184 (+) NCBI GRCr8 GRCr8 GRCr8 GRCr8 Ensembl 3 167,102,859 - 167,206,374 (+) Ensembl GRCr8 mRatBN7.2 3 146,682,975 - 146,729,251 (+) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 3 146,682,922 - 146,786,452 (+) Ensembl mRatBN7.2 UTH_Rnor_SHR_Utx 3 150,508,298 - 150,554,579 (+) NCBI UTH_Rnor_SHR_Utx UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 3 159,008,048 - 159,054,327 (+) NCBI UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 3 156,749,375 - 156,795,678 (+) NCBI UTH_Rnor_WKY_Bbb_1.0 UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 3 154,507,029 - 154,553,312 (+) NCBI Rnor_6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 3 154,507,035 - 154,553,312 (+) Ensembl rn6 Rnor6.0 Rnor_5.0 3 161,050,861 - 161,097,241 (-) NCBI Rnor_5.0 Rnor_5.0 rn5 RGSC_v3.4 3 148,736,594 - 148,783,743 (+) NCBI RGSC_v3.4 RGSC_v3.4 rn4 Celera 3 145,384,095 - 145,430,271 (+) NCBI Celera RGSC_v3.1 3 148,642,866 - 148,687,424 (+) NCBI Cytogenetic Map 3 q42 NCBI
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Imported Disease Annotations - ClinVar
Only show annotations with direct experimental evidence (0 objects hidden)
Rprd1b Rat (1->4)-beta-D-glucan multiple interactions ISO Rprd1b (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of RPRD1B mRNA CTD PMID:36331819 Rprd1b Rat 1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene multiple interactions ISO Rprd1b (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Rprd1b Rat 1,2-dimethylhydrazine multiple interactions EXP 6480464 [APC protein affects the susceptibility to 1,2-Dimethylhydrazine] which results in increased expression of RPRD1B mRNA CTD PMID:27840820 Rprd1b Rat 1,2-dimethylhydrazine increases expression ISO Rprd1b (Mus musculus) 6480464 1,2-Dimethylhydrazine results in increased expression of RPRD1B mRNA CTD PMID:22206623 Rprd1b Rat 2,2',4,4',5,5'-hexachlorobiphenyl decreases expression ISO RPRD1B (Homo sapiens) 6480464 2,4,5,2',4',5'-hexachlorobiphenyl results in decreased expression of RPRD1B mRNA CTD PMID:23146750 Rprd1b Rat 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO Rprd1b (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Rprd1b Rat 2,2',5,5'-tetrachlorobiphenyl multiple interactions ISO Rprd1b (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Rprd1b Rat 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Rprd1b (Mus musculus) 6480464 Tetrachlorodibenzodioxin affects the expression of RPRD1B mRNA CTD PMID:21570461 Rprd1b Rat 2,4,4'-trichlorobiphenyl multiple interactions ISO Rprd1b (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Rprd1b Rat 3-isobutyl-1-methyl-7H-xanthine multiple interactions ISO RPRD1B (Homo sapiens) 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] more ... CTD PMID:28628672 Rprd1b Rat 4,4'-sulfonyldiphenol increases expression ISO Rprd1b (Mus musculus) 6480464 bisphenol S results in increased expression of RPRD1B mRNA CTD PMID:39298647 Rprd1b Rat 4,4'-sulfonyldiphenol affects methylation ISO Rprd1b (Mus musculus) 6480464 bisphenol S affects the methylation of RPRD1B gene CTD PMID:31683443 Rprd1b Rat 5-fluorouracil increases expression ISO RPRD1B (Homo sapiens) 6480464 Fluorouracil results in increased expression of RPRD1B mRNA CTD PMID:15331170 Rprd1b Rat 5-fluorouracil affects response to substance ISO RPRD1B (Homo sapiens) 6480464 RPRD1B protein affects the susceptibility to Fluorouracil CTD PMID:15331170 Rprd1b Rat all-trans-retinoic acid increases expression ISO Rprd1b (Mus musculus) 6480464 Tretinoin results in increased expression of RPRD1B mRNA CTD PMID:16604517 Rprd1b Rat benzo[a]pyrene decreases expression ISO RPRD1B (Homo sapiens) 6480464 Benzo(a)pyrene results in decreased expression of RPRD1B protein CTD PMID:20097212 Rprd1b Rat benzo[a]pyrene increases expression ISO Rprd1b (Mus musculus) 6480464 Benzo(a)pyrene results in increased expression of RPRD1B mRNA CTD PMID:22228805 Rprd1b Rat bisphenol A increases expression ISO Rprd1b (Mus musculus) 6480464 bisphenol A results in increased expression of RPRD1B mRNA CTD PMID:26063408|PMID:33221593 Rprd1b Rat bisphenol A increases expression ISO RPRD1B (Homo sapiens) 6480464 bisphenol A results in increased expression of RPRD1B protein CTD PMID:37567409 Rprd1b Rat bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of RPRD1B mRNA CTD PMID:30816183 Rprd1b Rat bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of RPRD1B mRNA CTD PMID:25181051 Rprd1b Rat bisphenol F multiple interactions ISO RPRD1B (Homo sapiens) 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] more ... CTD PMID:28628672 Rprd1b Rat bisphenol F increases expression ISO Rprd1b (Mus musculus) 6480464 bisphenol F results in increased expression of RPRD1B mRNA CTD PMID:38685157 Rprd1b Rat cadmium atom multiple interactions ISO RPRD1B (Homo sapiens) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of RPRD1B more ... CTD PMID:35301059 Rprd1b Rat cadmium dichloride increases expression ISO RPRD1B (Homo sapiens) 6480464 Cadmium Chloride results in increased expression of RPRD1B protein CTD PMID:24527689 Rprd1b Rat cadmium dichloride multiple interactions ISO RPRD1B (Homo sapiens) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of RPRD1B more ... CTD PMID:35301059 Rprd1b Rat caffeine decreases phosphorylation ISO RPRD1B (Homo sapiens) 6480464 Caffeine results in decreased phosphorylation of RPRD1B protein CTD PMID:35688186 Rprd1b Rat copper(II) sulfate increases expression ISO RPRD1B (Homo sapiens) 6480464 Copper Sulfate results in increased expression of RPRD1B mRNA CTD PMID:19549813 Rprd1b Rat coumarin decreases phosphorylation ISO RPRD1B (Homo sapiens) 6480464 coumarin results in decreased phosphorylation of RPRD1B protein CTD PMID:35688186 Rprd1b Rat dexamethasone multiple interactions ISO RPRD1B (Homo sapiens) 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] more ... CTD PMID:28628672 Rprd1b Rat fenthion decreases expression ISO Rprd1b (Mus musculus) 6480464 Fenthion results in decreased expression of RPRD1B mRNA CTD PMID:34813904 Rprd1b Rat folic acid decreases expression ISO RPRD1B (Homo sapiens) 6480464 Folic Acid results in decreased expression of RPRD1B mRNA CTD PMID:21867686 Rprd1b Rat FR900359 increases phosphorylation ISO RPRD1B (Homo sapiens) 6480464 FR900359 results in increased phosphorylation of RPRD1B protein CTD PMID:37730182 Rprd1b Rat fulvestrant increases methylation ISO RPRD1B (Homo sapiens) 6480464 Fulvestrant results in increased methylation of RPRD1B gene CTD PMID:31601247 Rprd1b Rat indometacin multiple interactions ISO RPRD1B (Homo sapiens) 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] more ... CTD PMID:28628672 Rprd1b Rat ivermectin decreases expression ISO RPRD1B (Homo sapiens) 6480464 Ivermectin results in decreased expression of RPRD1B protein CTD PMID:32959892 Rprd1b Rat methidathion decreases expression ISO Rprd1b (Mus musculus) 6480464 methidathion results in decreased expression of RPRD1B mRNA CTD PMID:34813904 Rprd1b Rat methyl methanesulfonate increases expression ISO RPRD1B (Homo sapiens) 6480464 Methyl Methanesulfonate results in increased expression of RPRD1B mRNA CTD PMID:23649840 Rprd1b Rat methylparaben decreases expression ISO RPRD1B (Homo sapiens) 6480464 methylparaben results in decreased expression of RPRD1B mRNA CTD PMID:31745603 Rprd1b Rat paracetamol affects expression ISO Rprd1b (Mus musculus) 6480464 Acetaminophen affects the expression of RPRD1B mRNA CTD PMID:17562736 Rprd1b Rat paracetamol decreases expression ISO RPRD1B (Homo sapiens) 6480464 Acetaminophen results in decreased expression of RPRD1B mRNA CTD PMID:21420995 Rprd1b Rat PCB138 multiple interactions ISO Rprd1b (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Rprd1b Rat perfluorooctane-1-sulfonic acid multiple interactions ISO Rprd1b (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of RPRD1B mRNA CTD PMID:36331819 Rprd1b Rat raloxifene affects response to substance ISO RPRD1B (Homo sapiens) 6480464 RPRD1B protein affects the susceptibility to Raloxifene Hydrochloride CTD PMID:24452636 Rprd1b Rat resveratrol decreases expression ISO Rprd1b (Mus musculus) 6480464 resveratrol results in decreased expression of RPRD1B protein CTD PMID:25505154 Rprd1b Rat SB 431542 multiple interactions ISO RPRD1B (Homo sapiens) 6480464 [LDN 193189 co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with FGF2 protein] results in increased expression of RPRD1B more ... CTD PMID:37664457 Rprd1b Rat sodium arsenite affects expression ISO RPRD1B (Homo sapiens) 6480464 sodium arsenite affects the expression of RPRD1B mRNA CTD PMID:29319823 Rprd1b Rat titanium dioxide increases expression ISO Rprd1b (Mus musculus) 6480464 titanium dioxide results in increased expression of RPRD1B mRNA CTD PMID:29264374 Rprd1b Rat titanium dioxide decreases methylation ISO Rprd1b (Mus musculus) 6480464 titanium dioxide results in decreased methylation of RPRD1B promoter CTD PMID:35295148 Rprd1b Rat titanium dioxide affects methylation ISO Rprd1b (Mus musculus) 6480464 titanium dioxide affects the methylation of RPRD1B gene CTD PMID:35295148 Rprd1b Rat trichloroethene increases methylation EXP 6480464 Trichloroethylene results in increased methylation of RPRD1B gene CTD PMID:27618143 Rprd1b Rat triptonide affects expression ISO Rprd1b (Mus musculus) 6480464 triptonide affects the expression of RPRD1B mRNA CTD PMID:33045310 Rprd1b Rat troglitazone decreases expression ISO Rprd1b (Mus musculus) 6480464 troglitazone results in decreased expression of RPRD1B mRNA CTD PMID:28973697 Rprd1b Rat valproic acid affects expression ISO RPRD1B (Homo sapiens) 6480464 Valproic Acid affects the expression of RPRD1B mRNA CTD PMID:25979313 Rprd1b Rat valproic acid increases methylation ISO RPRD1B (Homo sapiens) 6480464 Valproic Acid results in increased methylation of RPRD1B gene CTD PMID:29501571 Rprd1b Rat valproic acid decreases expression ISO RPRD1B (Homo sapiens) 6480464 Valproic Acid results in decreased expression of RPRD1B mRNA; Valproic Acid results in decreased expression more ... CTD PMID:29501571 Rprd1b Rat vinclozolin decreases expression EXP 6480464 vinclozolin results in decreased expression of RPRD1B mRNA CTD PMID:23869203