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Gene: Acer2 (alkaline ceramidase 2) Rattus norvegicus

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Symbol:

Acer2

Name:

alkaline ceramidase 2

RGD ID:

1304629

Description:

Predicted to enable N-acylsphingosine amidohydrolase activity. Predicted to be involved in several processes, including DNA damage response, signal transduction by p53 class mediator; negative regulation of cell adhesion; and sphingolipid metabolic process. Predicted to be located in Golgi apparatus. Predicted to be active in Golgi membrane. Orthologous to human ACER2 (alkaline ceramidase 2); PARTICIPATES IN sphingolipid metabolic pathway; INTERACTS WITH 17beta-estradiol; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

Asah3l; LOC313339; N-acylsphingosine amidohydrolase 3-like

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	ACER2 (alkaline ceramidase 2)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Acer2 (alkaline ceramidase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Acer2 (alkaline ceramidase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	ACER2 (alkaline ceramidase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	ACER2 (alkaline ceramidase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Acer2 (alkaline ceramidase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	ACER2 (alkaline ceramidase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	ACER2 (alkaline ceramidase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Acer2 (alkaline ceramidase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Acer2 (alkaline ceramidase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	ACER2 (alkaline ceramidase 2)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Acer2 (alkaline ceramidase 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	acer2 (alkaline ceramidase 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	W02F12.2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	W02F12.2	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	bwa	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	bwa	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	acer2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER)
Xenopus tropicalis (tropical clawed frog):	acer2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	106,437,773 - 106,488,572 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	5	106,437,796 - 106,488,583 (+)	Ensembl				GRCr8
mRatBN7.2	5	101,391,830 - 101,442,615 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	101,391,885 - 101,442,614 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	5	103,772,875 - 103,817,891 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	105,563,430 - 105,608,446 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	105,596,792 - 105,641,922 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	105,230,540 - 105,279,732 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	105,230,580 - 105,279,731 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	5	109,217,448 - 109,266,600 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	5	106,185,779 - 106,237,588 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	5	101,644,752 - 101,692,910 (-)	NCBI		Celera
RGSC_v3.1	5	106,185,877 - 106,412,446 (+)	NCBI
Cytogenetic Map	5	q32	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(1->4)-beta-D-glucan (ISO)

(2,4,5-trichlorophenoxy)acetic acid (ISO)

1,1-dichloroethene (ISO)

1,2-dimethylhydrazine (ISO)

17beta-estradiol (EXP,ISO)

2,2',4,4'-Tetrabromodiphenyl ether (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2-hydroxypropanoic acid (ISO)

3,4-methylenedioxymethamphetamine (ISO)

3,7-dihydropurine-6-thione (EXP)

4,4'-sulfonyldiphenol (ISO)

4-hydroxyphenyl retinamide (ISO)

6-propyl-2-thiouracil (EXP)

acrylamide (ISO)

actinomycin D (ISO)

aflatoxin B1 (EXP,ISO)

aldrin (ISO)

all-trans-retinoic acid (ISO)

amiodarone (EXP)

atrazine (EXP)

benzo[a]pyrene (ISO)

beta-lapachone (ISO)

bisphenol A (EXP,ISO)

bromobenzene (EXP)

C60 fullerene (EXP)

cadmium dichloride (EXP)

camptothecin (ISO)

carbon nanotube (ISO)

carmustine (EXP)

chlordecone (ISO)

chloroethene (ISO)

chloroprene (EXP)

chlorpyrifos (ISO)

choline (ISO)

cisplatin (ISO)

crocidolite asbestos (ISO)

cypermethrin (ISO)

decabromodiphenyl ether (EXP)

dioxygen (ISO)

diuron (EXP)

doxorubicin (ISO)

epoxiconazole (ISO)

fipronil (EXP)

folic acid (ISO)

furan (EXP)

glafenine (EXP)

indole-3-methanol (EXP)

isoprenaline (ISO)

L-methionine (ISO)

lead diacetate (EXP)

mercaptopurine (EXP)

methimazole (EXP)

methotrexate (EXP,ISO)

N-Nitrosopyrrolidine (ISO)

Nutlin-3 (ISO)

okadaic acid (ISO)

oxaliplatin (EXP)

ozone (EXP,ISO)

paracetamol (EXP,ISO)

perfluorooctane-1-sulfonic acid (ISO)

perfluorooctanoic acid (EXP)

pirinixic acid (ISO)

pregnenolone 16alpha-carbonitrile (EXP,ISO)

purine-6-thiol (EXP)

rac-lactic acid (ISO)

resveratrol (EXP)

rotenone (EXP)

sirolimus (ISO)

sodium arsenite (ISO)

streptozocin (EXP)

sulforaphane (ISO)

sunitinib (ISO)

tebuconazole (ISO)

tetrachloromethane (EXP)

thioacetamide (EXP)

tioguanine (EXP)

titanium dioxide (EXP,ISO)

toluene (EXP)

topotecan (EXP)

tremolite asbestos (ISO)

triphenyl phosphate (EXP,ISO)

triptonide (ISO)

urethane (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

biological_process (ND)

cellular response to xenobiotic stimulus (ISO)

ceramide catabolic process (IBA,ISO)

ceramide metabolic process (IEA)

DNA damage response (ISO)

DNA damage response, signal transduction by p53 class mediator (ISO)

lipid metabolic process (IEA)

negative regulation of cell adhesion mediated by integrin (ISO)

negative regulation of cell-matrix adhesion (ISO)

positive regulation of cell population proliferation (ISO)

regulation of apoptotic process (ISO)

regulation of autophagy (ISO)

regulation of glycoprotein biosynthetic process (ISO)

response to retinoic acid (ISO)

sphingolipid metabolic process (IEA)

sphingosine biosynthetic process (IBA,IEA,ISO)

Cellular Component

Golgi apparatus (ISO)

Golgi membrane (IBA,ISO)

membrane (IEA)

Molecular Function

hydrolase activity (IEA)

hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides (IEA)

metal ion binding (IEA)

N-acylsphingosine amidohydrolase activity (IBA,IEA,ISO)

protein binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

sphingolipid metabolic pathway (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
3.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
5.	Comprehensive gene review and curation	RGD comprehensive gene curation

Additional References at PubMed

PMID:16940153	PMID:18945876	PMID:20089856	PMID:20207939	PMID:20628055	PMID:26943039	PMID:28294157	PMID:29229990	PMID:29401619

Genomics

Comparative Map Data

Acer2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	106,437,773 - 106,488,572 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	5	106,437,796 - 106,488,583 (+)	Ensembl				GRCr8
mRatBN7.2	5	101,391,830 - 101,442,615 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	101,391,885 - 101,442,614 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	5	103,772,875 - 103,817,891 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	105,563,430 - 105,608,446 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	105,596,792 - 105,641,922 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	105,230,540 - 105,279,732 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	105,230,580 - 105,279,731 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	5	109,217,448 - 109,266,600 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	5	106,185,779 - 106,237,588 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	5	101,644,752 - 101,692,910 (-)	NCBI		Celera
RGSC_v3.1	5	106,185,877 - 106,412,446 (+)	NCBI
Cytogenetic Map	5	q32	NCBI

ACER2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	9	19,409,009 - 19,452,505 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	9	19,409,009 - 19,452,505 (+)	Ensembl			hg38	GRCh38
GRCh37	9	19,409,007 - 19,452,503 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	9	19,398,925 - 19,442,500 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	9	19,335,075 - 19,378,570 (+)	NCBI		Celera
Cytogenetic Map	9	p22.1	NCBI
HuRef	9	19,370,525 - 19,414,024 (+)	NCBI		HuRef
CHM1_1	9	19,408,778 - 19,452,327 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	9	19,421,828 - 19,465,242 (+)	NCBI		T2T-CHM13v2.0

Acer2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	4	86,792,585 - 86,853,059 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	4	86,792,633 - 86,853,059 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	4	86,874,348 - 86,932,524 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	4	86,874,396 - 86,934,822 (+)	Ensembl			mm10	GRCm38
MGSCv37	4	86,520,318 - 86,566,785 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	4	86,345,695 - 86,392,106 (+)	NCBI		MGSCv36	mm8
Celera	4	85,395,108 - 85,439,689 (+)	NCBI		Celera
Cytogenetic Map	4	C4	NCBI
cM Map	4	40.69	NCBI

Acer2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955434	21,786,856 - 21,810,648 (+)	Ensembl
ChiLan1.0	NW_004955434	21,786,857 - 21,810,648 (+)	NCBI	ChiLan1.0	ChiLan1.0

ACER2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	11	105,092,977 - 105,139,449 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	9	105,098,921 - 105,145,396 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	9	19,216,891 - 19,262,477 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	9	19,706,716 - 19,751,057 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	9	19,709,402 - 19,750,896 (+)	Ensembl			panPan2	panpan1.1

ACER2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	11	39,190,873 - 39,223,590 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	11	39,190,115 - 39,219,776 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	11	37,848,571 - 37,881,294 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	11	40,124,209 - 40,156,941 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	11	40,124,252 - 40,156,909 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	11	38,816,668 - 38,849,382 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	11	38,614,132 - 38,646,861 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	11	39,248,101 - 39,280,836 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Acer2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	153,619,937 - 153,659,729 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936652	1,289,382 - 1,329,409 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936652	1,289,445 - 1,329,236 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ACER2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	203,384,726 - 203,414,972 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	1	203,387,669 - 203,415,018 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	227,035,770 - 227,065,826 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ACER2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	12	60,286,802 - 60,323,359 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	12	60,283,174 - 60,321,817 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666038	48,397,984 - 48,467,119 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Acer2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624736	23,363,983 - 23,411,100 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624736	23,363,806 - 23,556,247 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Acer2
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	1	67,101,172 - 67,144,922 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Acer2
346 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	533
Count of miRNA genes:	260
Interacting mature miRNAs:	352
Transcripts:	ENSRNOT00000010056
Prediction methods:	Miranda, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1357396	Bw44	Body weight QTL 44	4.19		body mass (VT:0001259)	body weight (CMO:0000012)	5	73779642	118779642	Rat
1331796	Thshl2	Thyroid stimulating hormone level QTL 2	2.3		blood thyroid-stimulating hormone amount (VT:0005119)	serum thyroid stimulating hormone level (CMO:0001248)	5	102105698	152749382	Rat
2303586	Gluco52	Glucose level QTL 52	2		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	5	100826632	145826632	Rat
1549845	Scl44	Serum cholesterol level QTL 44	6		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	5	44924861	153890773	Rat
70212	Niddm25	Non-insulin dependent diabetes mellitus QTL 25	3.54		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	5	38207390	136631402	Rat
1298070	Scl18	Serum cholesterol level QTL 18	3.7		blood LDL cholesterol amount (VT:0000181)	calculated plasma low density lipoprotein cholesterol level (CMO:0001245)	5	84630798	129630798	Rat
61452	Ciaa5	CIA Autoantibody QTL 5	3.5		blood autoantibody amount (VT:0003725)	calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)	5	99905133	172190305	Rat
1331801	Rf33	Renal function QTL 33	4.149		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal vascular resistance (CMO:0001900)	5	48523123	134369373	Rat
2302381	Bw84	Body weight QTL 84	4.47		body mass (VT:0001259)	body mass index (BMI) (CMO:0000105)	5	73779642	118779642	Rat
1357402	Bw46	Body weight QTL 46	4.47		body mass (VT:0001259)	body mass index (BMI) (CMO:0000105)	5	73779642	118779642	Rat
7411582	Foco3	Food consumption QTL 3	7.5	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	5	92583776	137583776	Rat
61393	Bp7	Blood pressure QTL 7	4.5	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	65089051	166764498	Rat
1598859	Cm66	Cardiac mass QTL 66	2		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	5	84630798	129630798	Rat
1578766	Tcas11	Tongue tumor susceptibility QTL 11	4.12		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	5	51657967	166600247	Rat
1582212	Livw2	Liver weight QTL 2	3.5	0.0004	liver mass (VT:0003402)	liver weight to body weight ratio (CMO:0000633)	5	104018576	124314782	Rat
7411564	Bw135	Body weight QTL 135		0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	5	92583776	137583776	Rat
8657050	Bw146	Body weight QTL 146	19.84	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	5	98972960	143972960	Rat
1576312	Emca8	Estrogen-induced mammary cancer QTL 8	4.1		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	55124766	172190305	Rat
7411601	Foco12	Food consumption QTL 12	19.7	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	5	92583776	137583776	Rat
2303618	Vencon1	Ventilatory control QTL 1	3.8		respiration trait (VT:0001943)	oxygen consumption (CMO:0002169)	5	100826632	145826632	Rat
7394708	Emca11	Estrogen-induced mammary cancer QTL 11			mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	73176602	118176602	Rat
1598846	Bp293	Blood pressure QTL 293	3.9		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	84630798	129630798	Rat
7394710	Emca12	Estrogen-induced mammary cancer QTL 12			mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	94034903	139034903	Rat
1578673	Bmd13	Bone mineral density QTL 13	4.9		femur mineral mass (VT:0010011)	trabecular volumetric bone mineral density (CMO:0001729)	5	69474415	114474415	Rat
1358909	Kidm25	Kidney mass QTL 25	1.87		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	5	95062526	133270832	Rat
70189	Mcs5	Mammary carcinoma susceptibility QTL 5	10.51		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	60601597	137492949	Rat
2290448	Scl54	Serum cholesterol level QTL 54	2.93		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	5	36460764	136631402	Rat
61426	Scl2	Serum cholesterol level QTL 2	7.3	0.001	blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	5	64589016	109589016	Rat
1354598	Srn6	Serum renin concentration QTL 6	3.8		blood renin amount (VT:0003349)	plasma renin activity level (CMO:0000116)	5	74335621	156302135	Rat
1600362	Mcs19	Mammary carcinoma susceptibility QTL 19	2.5		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	82032155	127032155	Rat
1298086	Bp156	Blood pressure QTL 156			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	89369373	134369373	Rat
2290005	Mcs24	Mammary carcinoma susceptibility QTL 24			mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	69835120	114835120	Rat
2306971	Anxrr21	Anxiety related response QTL 21	9.47		fear/anxiety-related behavior trait (VT:1000241)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	5	70969494	136328156	Rat
1358895	Bp254	Blood pressure QTL 254	3.6	0.0003	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	5	97492524	133270832	Rat
2312671	Scl64	Serum cholesterol level QTL 64		0.001	blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	5	73779642	118779642	Rat
6903316	Bw113	Body weight QTL 113	2	0.0103	body mass (VT:0001259)	body weight (CMO:0000012)	5	92881678	137881678	Rat
1358889	Bp261	Blood pressure QTL 261	2.86		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	5	95062526	133270832	Rat
1358187	Emca1	Estrogen-induced mammary cancer QTL 1	4.4		mammary gland integrity trait (VT:0010552)	post-insult time to mammary tumor formation (CMO:0000345)	5	104262817	153890625	Rat

Markers in Region

RH129365

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	5	101,442,257 - 101,442,473 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	105,279,375 - 105,279,590	NCBI	Rnor6.0
Rnor_5.0	5	109,266,243 - 109,266,458	UniSTS	Rnor5.0
RGSC_v3.4	5	106,237,232 - 106,237,447	UniSTS	RGSC3.4
Celera	5	101,644,893 - 101,645,108	UniSTS
RH 3.4 Map	5	739.7	UniSTS
Cytogenetic Map	5	q32	UniSTS

RH137105

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	5	101,442,267 - 101,442,468 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	105,279,385 - 105,279,585	NCBI	Rnor6.0
Rnor_5.0	5	109,266,253 - 109,266,453	UniSTS	Rnor5.0
RGSC_v3.4	5	106,237,242 - 106,237,442	UniSTS	RGSC3.4
Celera	5	101,644,898 - 101,645,098	UniSTS
RH 3.4 Map	5	739.3	UniSTS
Cytogenetic Map	5	q32	UniSTS

RH142072

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	5	101,439,761 - 101,439,970 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	105,276,879 - 105,277,087	NCBI	Rnor6.0
Rnor_5.0	5	109,263,747 - 109,263,955	UniSTS	Rnor5.0
RGSC_v3.4	5	106,234,737 - 106,234,945	UniSTS	RGSC3.4
Celera	5	101,647,395 - 101,647,603	UniSTS
RH 3.4 Map	5	737.5	UniSTS
Cytogenetic Map	5	q32	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	162	91	90	59	91	59	6	355	191	11	141	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001107943	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039109889	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_010066399	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_010066400	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH474094	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ225241	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ229191	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000010056 ⟹ ENSRNOP00000010056

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	5	106,437,875 - 106,488,583 (+)	Ensembl
mRatBN7.2 Ensembl	5	101,391,885 - 101,442,614 (+)	Ensembl
Rnor_6.0 Ensembl	5	105,230,580 - 105,279,731 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000115639 ⟹ ENSRNOP00000094342

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	5	106,437,875 - 106,488,583 (+)	Ensembl
mRatBN7.2 Ensembl	5	101,391,885 - 101,442,614 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000129708 ⟹ ENSRNOP00000102571

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	5	106,437,848 - 106,482,221 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000170865 ⟹ ENSRNOP00000110824

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	5	106,437,796 - 106,484,775 (+)	Ensembl

RefSeq Acc Id:

NM_001107943 ⟹ NP_001101413

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	106,437,848 - 106,488,571 (+)	NCBI
mRatBN7.2	5	101,391,885 - 101,442,614 (+)	NCBI
Rnor_6.0	5	105,230,580 - 105,279,731 (+)	NCBI
Rnor_5.0	5	109,217,448 - 109,266,600 (+)	NCBI
RGSC_v3.4	5	106,185,779 - 106,237,588 (+)	RGD
Celera	5	101,644,752 - 101,692,910 (-)	RGD

Sequence:

show sequence

GCACCGCATAAGCCGCAGACGCACAGTGTGCCCAGCAGCCGCTCGGGCCGCTTGCAGCTGCCGG
CTGCTCCGATGCTCCAGAGCGGCCATGGGCGCCCCGCACTGGTGGGACCAGCTGCGGGCTGGCA
GCTCGGAGGTGGATTGGTGCGAGGACAACTACACCATCGTGCCTGCCATCGCCGAGTTCTACAA
CACGATCAGCAACGTCCTGTTTTTCATTTTACCGCCCATCTGCATGTGCTTGTTCCGCCAGTAC
GCCACGTGCTTCAACAGCGGCATCTATTTAATATGGACTCTCCTAGTTGTAGTGGGAATCGGAT
CTGTCTACTTCCATGCAACTCTTAGTTTCCTGGGCCAGATGCTTGATGAACTTGCCATTCTTTG
GGTTCTGATGTGTGCTTTGGCCATGTGGTTTCCCAGGAGGTATTTACCAAAGATCTTTCGGAAT
GACAGGGGCAGGTTCAAGGCAGTGGTGTGTGTCCTGTCTGCAGTTACAACATGCCTGGCGTTTG
TCAAGCCTGCTATCAACAATATCTCTCTGATGATTCTGGGGGTTCCGTGCACTGCGCTGCTCAT
TGCAGAGCTGAAGAGGTGTGACAATGTGCGTGTGTTTAAGCTGGGCCTCTTCTCTGGCCTTTGG
TGGACTCTGGCTCTCTTCTGCTGGATCAGTGACCGAGCCTTCTGTGAGCTGCTGTCCTCCTTTC
ACTTTCCCTACCTGCACTGCGTGTGGCACATCCTCATCTGCCTTGCCGCGTACCTGGGCTGCGT
GTGCTTCGCCTACTTCGATGCTGCCTCAGAGATACCCGAACAAGGTCCAGTCATCAGATTCTGG
CCCAGTGAGAAATGGGCTTTTATCGGTGTCCCCTATGTGTCCCTCCTGTGTGCCCACAAGAAGT
CGCCAGTCAAGATCACGTGACGGCAAGGCAGTGACCGGCTTTTCTGCTTACTTCTATTCGAGTG
TGCTCTGGGCTTTGTTTGCTAGAAAAGATGGCCAAGGGGTTTGAAGAATTGATGTAGTGTGGGT
GTTTAAAATTCTGTTCTTTTGTGATCTAACTGGACCGCTGTGCCTGACATCCCCAGGGTGGGTA
ATGGAGGGCTCAGGGACATGAGTGGGTCGGCCTCAGCGACCTTTACGGGCACATGGGCTTGCTG
TGTTATATCCATGATGACATTGACAGAGTAGTTATTTGGGAGACCCAGAGCAGCCCAAAGCTTC
TTGCTGGAAAAGGTGGCTTGCCATAGCCCCCACCATTTCCAGGCTCTCTCATTACACAGGAGTC
AGCCCCCTGATTCTGTGATAGAAGGTTCCAGAACTTTTCATTTTGCTGGGAGAAACTGTCCTTC
AACAAAATCGAGTAGGCAAAAAAAAAAAAAACCAAAAAAAAACAAAAAAAACAAAAAAAAAAAC
AAAAAAAAAAACAAAAAAAAAAACAAAACAAAAAACCACACACACACACACATGGGGGGCTGTG
ACTAAGGCCGTGGCTTGTCACTTGCACCTCTTAGCTTTCTCCACATGCCTGTGGATCCTTCCAC
TACCTCTGCTGAGAGACGGAGCCTTGGCTTCAGAGGGCAAAGCCAGTAACACCCTCTACGCCAA
GAGCTACAGTCCACTTTAAGCACACATTAAACACTGACATTATGTCTGCTCTTCCAGAGTGCAG
CAGCCTCAGACCCACAGAGGCTCCTTCTGGTGTGGCAATTCCACACATAGCCCCCTACCGCTTG
CCACTTGACCTCTGTGAGAGCAAGGACTCATTGCACTCACTGAGGCAGCTCTGAGGGTTTTGAT
TGTAGAGCTCCTGTGAAGCTTTTGGAAAAGCTTTTCTTATTGGAAGCTTACAGTGTGTTGTTAC
CTCCAAGACTCTGACCCCATTTCTCTGCTGTTTTCAGGGGATGTGTGCTTCCTGAGGGATGCCA
CTTCCCTGGGATGTGGACCTCCAGCCTTTATTTTTGTAATACCGGTGCTAACTGGTTTCTCAGA
GCCCTTTGCTCTTCTTGATGCTGGCCAGTCACGACACTCTGATTGGCTGGCTAGGGGGTCACAG
GTAGGAAGGGGCAGACTCTGACCTGAATGTCTCTCACCTGCACCATGCTGTCCTCACTGGGCTA
TCTGCAGGGTATGAGGTGGAATTGGGTATATCTCAGGGATGTTTGTAACTCAGGCACCTTCTGC
TTTCTGACATTCCATTGTTGGGGTGGGACAGCGCTCAGGGGACTGCAGTTGCTACACTGTTCTG
AGTGGCGTCCTGAGTTTGAAGGAGTTGGCCGGTTCTGGCCGTTCCAGGAACTCTTACTCCGTAT
AGAAGCTTCACAGGGTCCAAAGTGGAAACTGGACTAGGAGTTTTTAAATGCATAGGCTTCATTC
TGCTTCTGGGGCTTTGAAGTTTTAGAAGTAGCTTGCTAGGCTCTTTCTTGTCTGTAGTCACAAA
TATCTGTAGAACCCGAATGTGTGAAAGAAGTCATCTTTTATTAAGTTTATAGCATTTACTAAAT
CTCCCAGGTAGCAAGCCCATAGTCATTTATTTGATTGGTGATTTATAAGGCAGAGATACTTGGC
TTTGAATGACTGTATATGTTATTTTATTGCAGCTTAAAATATATTTAAAATGATTTTGAGTTAA
ATGTTTGTGGCAACCTAGGGGGGTTCATGGACCAGAATTGCTGCTGAGTCCTTTGGTTTTTGAG
TCTAGAATTTTTCAGACTAGCCTTGCTTCCAGCTCATCTCACCAGGCACAGGGGCTGCTCTTAT
ATATTCTACACGATATACACATCCTGAGGATGACGCCGAGCTGCCTTTGTCTGAAAGGGCCCGA
GCTGTCTGGGGCTGGAGAGCTGGTTCAGCCGATAAAAACACATGTTGCCCTCCCAGAGGACCCA
GGTTTGATTCCCAGCATCTTATAAAGCTGACAACCTGTAGCTCCAGTCCCAGGGGATCCAGTGC
CCTCTTCTGACCTCCAAGGGCACAGAGCATGCATGTGGTACACCTATGCATACAGGCAGGCAAG
TCATTCGTACATGTAAAGTAATGAGTAAGTTAATAAGCCGGCGGAGGGAAAGGTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTGGGTCTTTTTTTTTTTCGGAGCTGGGGACCGAACCCA
GGGCCTTGCGCTTCCTAGGTAAGCGCTCTACCACTGAGCTAAATCCCCAGCCCCGGGAAAGGGT
TTTTAGATGCAAGGTTTAGTTTGTCCTGGGGGCCCTTCCATGACAGTGGGGGTGTCCTCAGAGT
CAGGGAAGAACCACTTCTTTTTATCAGGAAAAAGGACTTATTTCCCAGGGCCTCTGCTAACACC
CCTAGGTATAGGTATAGGGATAAGATATTAATGGGTGTGCTTGAACGATTGGGTGAAAGGAGAT
GAGAACCTGACTCGACTCAGTGGGCCTCTTCCCCAGGTGTGTGAGCCACCATAGCTGGCTTGGT
AGGGAGTGTGTTTGGGGGCAAGCCCTACCCCCCCTCTGAGACAAAGCTCTGATCTTTTTCATGT
CTCAGGCTGTATTCACTGTATAGTTCAGGCTAGCCTCAAACTGACGGTGAGACCCCAAGTGCTA
GGTATACTTATAGGAGCAAGGTACCACACCCACTTTAAAACAGAAATCTCTCCTGCTTGCTAGC
ATGGGCCTGACTAATCAAGGGAGTAGATACATATGAATCTAACTTTGAGCTGGGCTTTGAGCAT
TGATCACTTTTTTATTAAAGCTTTACACGATCACTCCATGGGACACTACAGAAGAGCGGCAGAA
GAAAAAGTTACTCATACCTCTCTTGCCTTAGAGCCTCCGTCACCAATTTGGCTTTGGGGCGTGT
TTCCTTCCTCTCCTTTCTGCTCTCCTACAGTTATAATGAGATTTCATTTAGACCGCTTTCCCTT
GAGTGGAATATGCATGGCAGCGTTTTCATGGAGAGCTAACTTTCTCTCCTATGCTGACGGCTGG
ACGCTGAGCTCACCACTGAAGCTGCCTTTCCCATGAAGTCCGACTTGAGAGGCTCCTAAGACAT
GAACTGATTTTGGCTTTGCGATGTAACAATTCACATTTGGGTCTCTGAGTTGTGGAGAGCCGCT
GTTAAAGCTCTGACTTCATGGCTCCTACTGTGTTGAGAGTGGTGACAAGAAGCAGAGCAGGCTA
ACTGATGTGCACTCCAGAATCTGCTCCCTTCTGGTAGAGATGACCTCAGTGAGTGATGTCATGG
CCACTGTTCCCAGCATGGGCGTCAGGTTCTGCTCTGTTCCGAATCTGCCTGGGATCTCAGGACA
GAGGAAGCCATGAAGGTTACCAAGTGGTCATGTCTGTCAGTGAGTTCACTGTTTTGATCCATTG
TTGATTTTCAGGAGAGGAATTCTTCTCTCTTTAGTGCCCTGTGATGCCAAAGCCAGCTCTTCAG
AAGTGTTTTTTCTGTCTGCTTCCATTTGTAATGTGATCCACGTGGGGGAAATGGGTGTCATTCT
GCTGAAAAGTGCCTAAACCAGTCACGGGTCAACAGCATTGTGTGGAGGATCAAACGTGGCTCTG
TAGAAATACTGCCACCCATTCTATTGGTTGGACTTCTCAGGTGTCTGAAACTTCCCTCACGAAT
CCTCTTCTCCTAACCGCCTCCCAGATCCACTGGGATTTGAACCTTCAAATCCTGCCTCTCTTCT
TCCTTCAGGTCTGACCACTAACGGTCTCTGGGGACACCTAACTAGGGCCTCCCCCAGCTCCTTC
CTCCAGCCGAACTTGGATTCTTCCCAACCAGGGCTTGACCTGGGTGCTGTTGGTCCCACTGCCC
AATGACACATCTTTGACCAGATTGGGATTCTCAATAGATTTTATAGACATTATTCTCCCACAGA
CTTTAAAAAACATGGCGTGTGTCTTTTCCTACACAAGTCAGATTTAAAACTATTTTATAACTAC
AATAATTCAACCAAGCAAATAGAGTATTTTCAGATATATGCCATTTTATACTTTATGTAGAGTG
TGCTATGTACAGGTGGCATGTACCCTGGCTGAGGTAACATTAGTCATTGCTCTGGGGGATTTAC
AGATCTTTTGCACTTTATGCTTTTTTTGTGAACTCTGATAACCATGTTCAATATTAAAGCCATT
AACAGGCATTTTCTGTGAATAAACATTTATGTATCT

hide sequence

RefSeq Acc Id:

XM_039109889 ⟹ XP_038965817

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	106,437,784 - 106,482,554 (+)	NCBI
mRatBN7.2	5	101,391,830 - 101,436,511 (+)	NCBI

RefSeq Acc Id:

XR_010066399

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	106,437,773 - 106,488,572 (+)	NCBI

RefSeq Acc Id:

XR_010066400

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	106,437,784 - 106,484,282 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001101413	(Get FASTA)	NCBI Sequence Viewer
	XP_038965817	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL76006	(Get FASTA)	NCBI Sequence Viewer
	EDL76007	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000010056
	ENSRNOP00000010056.4
	ENSRNOP00000094342.1
	ENSRNOP00000102571.1
	ENSRNOP00000110824.1

RefSeq Acc Id:

NP_001101413 ⟸ NM_001107943

- UniProtKB:

D3ZNW4 (UniProtKB/TrEMBL), A6KRB3 (UniProtKB/TrEMBL), A0A8I6B090 (UniProtKB/TrEMBL), A6KRB2 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MGAPHWWDQLRAGSSEVDWCEDNYTIVPAIAEFYNTISNVLFFILPPICMCLFRQYATCFNSGI
YLIWTLLVVVGIGSVYFHATLSFLGQMLDELAILWVLMCALAMWFPRRYLPKIFRNDRGRFKAV
VCVLSAVTTCLAFVKPAINNISLMILGVPCTALLIAELKRCDNVRVFKLGLFSGLWWTLALFCW
ISDRAFCELLSSFHFPYLHCVWHILICLAAYLGCVCFAYFDAASEIPEQGPVIRFWPSEKWAFI
GVPYVSLLCAHKKSPVKIT

hide sequence

Ensembl Acc Id:

ENSRNOP00000010056 ⟸ ENSRNOT00000010056

RefSeq Acc Id:	XP_038965817 ⟸ XM_039109889
- Peptide Label:	isoform X1

Ensembl Acc Id:

ENSRNOP00000094342 ⟸ ENSRNOT00000115639

Ensembl Acc Id:

ENSRNOP00000110824 ⟸ ENSRNOT00000170865

Ensembl Acc Id:

ENSRNOP00000102571 ⟸ ENSRNOT00000129708

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZNW4-F1-model_v2	AlphaFold	D3ZNW4	1-275	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13693826

Promoter ID:

EPDNEW_R4351

Type:

multiple initiation site

Name:

Acer2_1

Description:

alkaline ceramidase 2

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	5	105,230,616 - 105,230,676	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1304629	AgrOrtholog
BioCyc Gene	G2FUF-40837	BioCyc
Ensembl Genes	ENSRNOG00000007637	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000010056	ENTREZGENE
	ENSRNOT00000010056.8	UniProtKB/TrEMBL
	ENSRNOT00000115639.2	UniProtKB/TrEMBL
	ENSRNOT00000129708.1	UniProtKB/TrEMBL
	ENSRNOT00000170865	ENTREZGENE
	ENSRNOT00000170865.1	UniProtKB/TrEMBL
InterPro	Ceramidase	UniProtKB/TrEMBL
KEGG Report	rno:313339	UniProtKB/TrEMBL
NCBI Gene	313339	ENTREZGENE
PANTHER	ALKALINE CERAMIDASE 2	UniProtKB/TrEMBL
	PTHR46139	UniProtKB/TrEMBL
Pfam	aPHC	UniProtKB/TrEMBL
PhenoGen	Acer2	PhenoGen
RatGTEx	ENSRNOG00000007637	RatGTEx
UniProt	A0A8I6B090	ENTREZGENE, UniProtKB/TrEMBL
	A0ABK0LIU3_RAT	UniProtKB/TrEMBL
	A0ABK0LMH3_RAT	UniProtKB/TrEMBL
	A6KRB2	ENTREZGENE, UniProtKB/TrEMBL
	A6KRB3	ENTREZGENE, UniProtKB/TrEMBL
	D3ZNW4	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2009-01-05	Acer2	alkaline ceramidase 2	Asah3l	N-acylsphingosine amidohydrolase 3-like	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	Asah3l	N-acylsphingosine amidohydrolase 3-like	Asah3l_predicted	N-acylsphingosine amidohydrolase 3-like (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Asah3l_predicted	N-acylsphingosine amidohydrolase 3-like (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Annotations - KEGG (archival)