Nrf1 (nuclear respiratory factor 1) - Rat Genome Database

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Gene: Nrf1 (nuclear respiratory factor 1) Rattus norvegicus
Analyze
Symbol: Nrf1
Name: nuclear respiratory factor 1
RGD ID: 1304603
Description: Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including response to estradiol; response to folic acid; and response to lipopolysaccharide. Predicted to be located in cytosol and nucleoplasm. Biomarker of obesity. Human ortholog(s) of this gene implicated in Huntington's disease. Orthologous to human NRF1 (nuclear respiratory factor 1); PARTICIPATES IN Huntington's disease pathway; INTERACTS WITH (+)-schisandrin B; (R)-noradrenaline; 17beta-estradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: alpha palindromic-binding protein; alpha-pal; LOC312195; Nfe2l1_retired; NRF-1; nuclear factor (erythroid-derived 2)-like 1; nuclear respiratory factor-1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8459,632,366 - 59,738,166 (+)NCBIGRCr8
mRatBN7.2458,664,932 - 58,772,328 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl458,664,957 - 58,825,328 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx463,642,477 - 63,739,391 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0459,558,637 - 59,655,557 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0457,960,536 - 58,057,462 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0457,335,732 - 57,445,317 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl457,378,069 - 57,445,341 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0457,097,471 - 57,207,118 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4456,949,553 - 57,048,149 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1457,267,163 - 57,331,137 (+)NCBI
Celera453,766,265 - 53,861,921 (+)NCBICelera
Cytogenetic Map4q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(R)-noradrenaline  (EXP)
1-chloro-2,4-dinitrobenzene  (ISO)
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine  (ISO)
17beta-estradiol  (EXP,ISO)
1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one  (EXP,ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,3-bis(4-hydroxyphenyl)propionitrile  (ISO)
2,4-dinitrophenol  (ISO)
3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine  (EXP)
3,4-methylenedioxymethamphetamine  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3-phenylprop-2-enal  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
8-bromo-3',5'-cyclic GMP  (ISO)
acadesine  (ISO)
acetylsalicylic acid  (ISO)
acrolein  (EXP)
afimoxifene  (ISO)
aflatoxin B1  (ISO)
AICA ribonucleotide  (EXP)
aldehydo-D-glucose  (EXP)
all-trans-retinoic acid  (EXP)
alloxan  (EXP)
AM-251  (ISO)
amitrole  (EXP)
ammonium chloride  (EXP)
antirheumatic drug  (ISO)
arachidonyl-2'-chloroethylamide  (ISO)
Aroclor 1254  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
atorvastatin calcium  (EXP)
atrazine  (EXP,ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP)
Butylbenzyl phthalate  (ISO)
cadmium atom  (EXP)
cadmium dichloride  (EXP)
caffeine  (EXP)
calcitriol  (EXP)
calycosin  (EXP)
carbon monoxide  (EXP,ISO)
CHIR 99021  (ISO)
cisplatin  (ISO)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
cyprodinil  (ISO)
D-glucose  (EXP)
dexamethasone  (ISO)
Di-n-octyl phthalate  (ISO)
diarsenic trioxide  (ISO)
Dibutyl phosphate  (ISO)
dioxygen  (EXP,ISO)
dorsomorphin  (EXP)
doxorubicin  (ISO)
elemental selenium  (EXP)
enalapril  (EXP)
enniatin  (EXP)
enzyme inhibitor  (ISO)
Erythropoietin  (ISO)
ethidium  (ISO)
fenthion  (ISO)
fenvalerate  (EXP)
fludioxonil  (ISO)
Flumetralin  (ISO)
formaldehyde  (ISO)
FR900359  (ISO)
fulvestrant  (ISO)
gamma-hexachlorocyclohexane  (ISO)
Genipin  (ISO)
Gingerenone A  (ISO)
glucose  (EXP)
hemin  (EXP)
hexadecanoic acid  (ISO)
hydrogen peroxide  (ISO)
indinavir  (ISO)
isoniazide  (ISO)
lenvatinib  (EXP)
Licarin A  (ISO)
losartan  (EXP)
LY294002  (EXP,ISO)
manganese(II) chloride  (EXP)
melatonin  (EXP)
mepanipyrim  (ISO)
metformin  (ISO)
methamphetamine  (ISO)
methidathion  (ISO)
methimazole  (EXP)
methoxyacetic acid  (EXP)
methylglyoxal  (EXP)
methylmercury chloride  (EXP)
mitomycin C  (ISO)
monascin  (EXP)
mono(2-ethylhexyl) phthalate  (ISO)
Monobutylphthalate  (EXP)
monocrotophos  (EXP)
N-acetyl-L-cysteine  (EXP)
N-methyl-4-phenylpyridinium  (ISO)
nickel atom  (ISO)
nickel dichloride  (ISO)
oleic acid  (ISO)
oxaliplatin  (EXP)
oxybenzone  (EXP)
ozone  (ISO)
p-toluidine  (EXP)
paracetamol  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP)
potassium chloride  (EXP)
pregnenolone 16alpha-carbonitrile  (EXP)
propham  (ISO)
pyrimethanil  (ISO)
pyrroloquinoline quinone  (ISO)
quercetin  (EXP)
raloxifene  (ISO)
reactive oxygen species  (ISO)
resveratrol  (EXP,ISO)
rotenone  (ISO)
salvianolic acid B  (ISO)
selenium atom  (EXP)
sodium arsenite  (EXP,ISO)
sodium hydrogensulfite  (EXP)
Soman  (EXP)
stavudine  (ISO)
sulforaphane  (ISO)
sulfur dioxide  (EXP)
T-2 toxin  (EXP,ISO)
tetrachloromethane  (EXP)
thapsigargin  (ISO)
titanium dioxide  (ISO)
topotecan  (EXP)
trimellitic anhydride  (ISO)
Triptolide  (EXP,ISO)
triptonide  (ISO)
troglitazone  (EXP)
tunicamycin  (ISO)
uranium atom  (ISO)
urethane  (ISO)
valproic acid  (ISO)
zidovudine  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytosol  (IEA,ISO)
nucleoplasm  (IEA,ISO)
nucleus  (IEA)

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Impairment of PGC-1alpha expression, neuropathology and hepatic steatosis in a transgenic mouse model of Huntington's disease following chronic energy deprivation. Chaturvedi RK, etal., Hum Mol Genet. 2010 Aug 15;19(16):3190-205. Epub 2010 Jun 7.
2. Changes in mitochondrial DNA deletion, content, and biogenesis in folate-deficient tissues of young rats depend on mitochondrial folate and oxidative DNA injuries. Chou YF, etal., J Nutr. 2007 Sep;137(9):2036-42.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
5. Stimulation of mitochondrial biogenesis and autophagy by lipopolysaccharide in the neonatal rat cardiomyocyte protects against programmed cell death. Hickson-Bick DL, etal., J Mol Cell Cardiol. 2008 Feb;44(2):411-8. Epub 2007 Dec 11.
6. Nrf2 signaling in coordinated activation of antioxidant gene expression. Jaiswal AK Free Radic Biol Med 2004 May 15;36(10):1199-207.
7. Increases in the mitochondrial DNA replication and transcription in the remnant liver of rats. Koyama H, etal., Biochem Biophys Res Commun. 1998 Feb 24;243(3):858-61.
8. Sustained hypoxia modulates mitochondrial DNA content in the neonatal rat brain. Lee HM, etal., Free Radic Biol Med. 2008 Mar 1;44(5):807-14. Epub 2007 Nov 21.
9. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
10. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
11. GOA pipeline RGD automated data pipeline
12. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
13. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
14. Comprehensive gene review and curation RGD comprehensive gene curation
15. Estrogen increases mitochondrial efficiency and reduces oxidative stress in cerebral blood vessels. Stirone C, etal., Mol Pharmacol. 2005 Oct;68(4):959-65. Epub 2005 Jun 30.
16. Lipopolysaccharide stimulates mitochondrial biogenesis via activation of nuclear respiratory factor-1. Suliman HB, etal., J Biol Chem 2003 Oct 17;278(42):41510-8. Epub 2003 Aug 05.
17. PGC-1alpha downstream transcription factors NRF-1 and TFAM are genetic modifiers of Huntington disease. Taherzadeh-Fard E, etal., Mol Neurodegener. 2011 May 19;6(1):32.
18. Activation of the cytochrome c gene by electrical stimulation in neonatal rat cardiac myocytes. Role of NRF-1 and c-Jun. Xia Y, etal., J Biol Chem. 1998 May 15;273(20):12593-8.
19. WY14643 improves left ventricular myocardial mitochondrial and systolic functions in obese rats under chronic persistent hypoxia via the PPARα pathway. Yan J, etal., Life Sci. 2021 Feb 1;266:118888. doi: 10.1016/j.lfs.2020.118888. Epub 2020 Dec 10.
20. Activity-dependent transcriptional regulation of nuclear respiratory factor-1 in cultured rat visual cortical neurons. Yang SJ, etal., Neuroscience. 2006 Sep 1;141(3):1181-92. Epub 2006 Jun 6.
21. Rapidly increased neuronal mitochondrial biogenesis after hypoxic-ischemic brain injury. Yin W, etal., Stroke. 2008 Nov;39(11):3057-63. Epub 2008 Aug 21.
22. Genomic modulation of mitochondrial respiratory genes in the hypertrophied heart reflects adaptive changes in mitochondrial and contractile function. Zungu M, etal., Am J Physiol Heart Circ Physiol. 2007 Nov;293(5):H2819-25. Epub 2007 Aug 17.
Additional References at PubMed
PMID:7629110   PMID:11134326   PMID:12477932   PMID:15384421   PMID:16230352   PMID:18252725   PMID:18990090   PMID:19056867   PMID:19615412   PMID:19674972   PMID:20438809   PMID:21609285  
PMID:23359427   PMID:23525105   PMID:26202310   PMID:27634749   PMID:28263745   PMID:28903152   PMID:30628711   PMID:31028793   PMID:31942725   PMID:32016449   PMID:33475136   PMID:33582931  
PMID:33913583   PMID:35180801   PMID:35569770  


Genomics

Comparative Map Data
Nrf1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8459,632,366 - 59,738,166 (+)NCBIGRCr8
mRatBN7.2458,664,932 - 58,772,328 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl458,664,957 - 58,825,328 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx463,642,477 - 63,739,391 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0459,558,637 - 59,655,557 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0457,960,536 - 58,057,462 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0457,335,732 - 57,445,317 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl457,378,069 - 57,445,341 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0457,097,471 - 57,207,118 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4456,949,553 - 57,048,149 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1457,267,163 - 57,331,137 (+)NCBI
Celera453,766,265 - 53,861,921 (+)NCBICelera
Cytogenetic Map4q22NCBI
NRF1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387129,611,720 - 129,757,076 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7129,611,720 - 129,757,082 (+)EnsemblGRCh38hg38GRCh38
GRCh377129,251,561 - 129,396,916 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 367129,038,791 - 129,184,158 (+)NCBINCBI36Build 36hg18NCBI36
Build 347128,845,547 - 128,989,805NCBI
Celera7124,047,294 - 124,192,656 (+)NCBICelera
Cytogenetic Map7q32.2NCBI
HuRef7123,613,242 - 123,758,239 (+)NCBIHuRef
CHM1_17129,185,036 - 129,330,325 (+)NCBICHM1_1
T2T-CHM13v2.07130,924,847 - 131,070,183 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v27128,635,837 - 128,781,204 (+)NCBI
Nrf1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39630,047,984 - 30,153,462 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl630,047,987 - 30,153,457 (+)EnsemblGRCm39 Ensembl
GRCm38630,047,985 - 30,153,458 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl630,047,988 - 30,153,458 (+)EnsemblGRCm38mm10GRCm38
MGSCv37629,997,988 - 30,103,458 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36629,997,998 - 30,103,468 (+)NCBIMGSCv36mm8
Celera630,053,407 - 30,160,369 (+)NCBICelera
Cytogenetic Map6A3.3NCBI
cM Map612.47NCBI
Nrf1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495547910,324,443 - 10,472,875 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495547910,325,214 - 10,471,421 (+)NCBIChiLan1.0ChiLan1.0
NRF1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26166,429,088 - 166,574,279 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1718,439,333 - 18,584,524 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v07121,574,061 - 121,719,604 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17134,095,925 - 134,240,158 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7134,113,482 - 134,240,158 (+)Ensemblpanpan1.1panPan2
NRF1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1147,085,018 - 7,218,802 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl147,085,791 - 7,193,034 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha146,770,310 - 6,906,180 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0146,848,014 - 6,983,992 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl146,848,018 - 6,983,930 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1147,053,598 - 7,189,532 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0146,795,757 - 6,931,636 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0146,940,039 - 7,075,975 (-)NCBIUU_Cfam_GSD_1.0
Nrf1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511825,291,442 - 25,427,802 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365795,423,773 - 5,561,003 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365795,424,049 - 5,560,355 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NRF1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1818,998,930 - 19,142,628 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11819,008,408 - 19,142,678 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
NRF1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12198,227,088 - 98,377,095 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2198,268,395 - 98,377,096 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660425,026,792 - 5,175,767 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nrf1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247836,488,380 - 6,602,250 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247836,488,653 - 6,654,304 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Nrf1
683 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:13
Count of miRNA genes:12
Interacting mature miRNAs:13
Transcripts:ENSRNOT00000011851
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2303585Bw86Body weight QTL 864body mass (VT:0001259)body weight (CMO:0000012)41467806559678065Rat
5685012Bmd87Bone mineral density QTL 875.1tibia mineral mass (VT:1000283)bone mineral content (CMO:0001554)45664777678882945Rat
1358352Srcrt3Stress Responsive Cort QTL 32.29blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)438465774146803430Rat
61445Strs3Sensitivity to stroke QTL 33cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)44043338885433388Rat
6893678Bw108Body weight QTL 1082.60.006body mass (VT:0001259)body weight (CMO:0000012)44345797688457976Rat
5685009Bmd86Bone mineral density QTL 863.7tibia mineral mass (VT:1000283)bone mineral density (CMO:0001226)45664777678882945Rat
10755501Bp390Blood pressure QTL 3902.5arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)426775591168368347Rat
1331807Rf31Renal function QTL 312.988urine potassium amount (VT:0010539)urine potassium level (CMO:0000128)43952426474726312Rat
8552782Vie1Viral induced encephalitis QTL 126.4brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)43443048482490359Rat
634311Sach7Saccharin preference QTL 7taste sensitivity trait (VT:0001986)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)45711443281266970Rat
1358363Sradr3Stress Responsive Adrenal Weight QTL 36.19adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)457486946102486946Rat
631261Tcas3Tongue tumor susceptibility QTL 36.88tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)41081417091360527Rat
2312567Glom19Glomerulus QTL 191.90.006kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)445456990146803430Rat
61336Bp21Blood pressure QTL 214.6arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)45711470578881294Rat
2313401Anxrr27Anxiety related response QTL 27aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)41793350862933508Rat
8655961Kidm43Kidney mass QTL 4318kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)436303261103194984Rat
1354612Foco1Food consumption QTL 18.87eating behavior trait (VT:0001431)food intake rate (CMO:0000427)444463908148090542Rat
6909128Pancm4Pancreatic morphology QTL 411.35pancreas mass (VT:0010144)pancreas wet weight (CMO:0000626)42690728575585128Rat
2303168Bp330Blood pressure QTL 3304.250.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)45214602146446691Rat
8552801Bw143Body weight QTL 1437.3body mass (VT:0001259)change in body weight to body weight ratio (CMO:0002216)43443048482490359Rat
61475Aia2Adjuvant induced arthritis QTL 25.8joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)43950527573892441Rat
8694439Bw168Body weight QTL 1689.570.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)44043341485433414Rat
61412Pia2Pristane induced arthritis QTL 23.9joint integrity trait (VT:0010548)post-insult time to onset of experimental arthritis (CMO:0001450)42133334362278020Rat
8655906Rf60Renal function QTL 603.8blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)42949419581006281Rat
619616Bp79Blood pressure QTL 790.0292arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)4521460278882945Rat
1576305Emca6Estrogen-induced mammary cancer QTL 65.8mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)444463720155883716Rat
7387227Uae40Urinary albumin excretion QTL 402.90.0052urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)41794699962946999Rat
6909122Insul22Insulin level QTL 224.63blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)42690728575585128Rat
8552809Vie5Viral induced encephalitis QTL 525.3brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)43443048482490359Rat
1558651Swd3Spike wave discharge measurement QTL 34.620.000024brain electrophysiology trait (VT:0010557)brain spike-and-wave discharge frequency (CMO:0001742)45843213392991462Rat
1358203Stl19Serum triglyceride level QTL 192.80.002blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)4521829465958103Rat
1354660Salc1Saline consumption QTL 111.26drinking behavior trait (VT:0001422)saline drink intake rate (CMO:0001627)444463908148090542Rat
1641833Alc21Alcohol consumption QTL 218.60.0001drinking behavior trait (VT:0001422)ethanol drink intake rate (CMO:0001407)456698790126192555Rat
1298082Stresp4Stress response QTL 4blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)450119848146803430Rat
631546Bp86Blood pressure QTL 863.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)45711443291360801Rat
1300139Hrtrt6Heart rate QTL 62.85heart pumping trait (VT:2000009)heart rate (CMO:0000002)439524264116179656Rat
70200Alc18Alcohol consumption QTL 189.2drinking behavior trait (VT:0001422)ethanol intake volume to total fluid intake volume ratio (CMO:0001591)456647873149491524Rat
12798520Anxrr55Anxiety related response QTL 554.450.01locomotor behavior trait (VT:0001392)number of rearing movements with lid-pushing in an experimental apparatus (CMO:0002715)432583980114627242Rat
4889969Bss96Bone structure and strength QTL 964.9tibia size trait (VT:0100001)tibia cortical bone volume (CMO:0001725)45664777678882945Rat
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)411320076180699135Rat
4889972Bss97Bone structure and strength QTL 975.6tibia size trait (VT:0100001)tibia total bone volume (CMO:0001724)45664777678882945Rat
631671Iddm11Insulin dependent diabetes mellitus QTL 113.60.0012blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)45863587778886137Rat

Markers in Region
PMC97559P1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2458,738,247 - 58,738,366 (+)MAPPERmRatBN7.2
Rnor_6.0457,412,609 - 57,412,727NCBIRnor6.0
Rnor_5.0457,174,410 - 57,174,528UniSTSRnor5.0
RGSC_v3.4457,024,097 - 57,024,215UniSTSRGSC3.4
Celera453,837,869 - 53,837,987UniSTS
Cytogenetic Map4q22UniSTS
RH130830  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2458,770,406 - 58,770,609 (+)MAPPERmRatBN7.2
Rnor_6.0457,444,990 - 57,445,192NCBIRnor6.0
Rnor_5.0457,206,791 - 57,206,993UniSTSRnor5.0
RGSC_v3.4457,056,254 - 57,056,456UniSTSRGSC3.4
Celera453,870,026 - 53,870,228UniSTS
RH 3.4 Map4308.6UniSTS
Cytogenetic Map4q22UniSTS
BF387640  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2458,693,032 - 58,693,202 (+)MAPPERmRatBN7.2
Rnor_6.0457,365,413 - 57,365,582NCBIRnor6.0
Rnor_5.0457,127,146 - 57,127,315UniSTSRnor5.0
RGSC_v3.4456,978,292 - 56,978,461UniSTSRGSC3.4
Celera453,794,310 - 53,794,479UniSTS
RH 3.4 Map4320.4UniSTS
Cytogenetic Map4q22UniSTS
RH127210  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2458,747,930 - 58,748,168 (+)MAPPERmRatBN7.2
Rnor_6.0457,422,291 - 57,422,528NCBIRnor6.0
Rnor_5.0457,184,092 - 57,184,329UniSTSRnor5.0
RGSC_v3.4457,033,780 - 57,034,017UniSTSRGSC3.4
Celera453,847,552 - 53,847,789UniSTS
Cytogenetic Map4q22UniSTS
RH136651  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2458,687,752 - 58,687,946 (+)MAPPERmRatBN7.2
Rnor_6.0457,360,134 - 57,360,327NCBIRnor6.0
Rnor_5.0457,121,867 - 57,122,060UniSTSRnor5.0
RGSC_v3.4456,972,319 - 56,972,512UniSTSRGSC3.4
Celera453,789,031 - 53,789,224UniSTS
RH 3.4 Map4318.6UniSTS
Cytogenetic Map4q22UniSTS
BE096654  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2458,758,309 - 58,758,508 (+)MAPPERmRatBN7.2
Rnor_6.0457,432,894 - 57,433,092NCBIRnor6.0
Rnor_5.0457,194,695 - 57,194,893UniSTSRnor5.0
RGSC_v3.4457,044,158 - 57,044,356UniSTSRGSC3.4
Celera453,857,930 - 53,858,128UniSTS
RH 3.4 Map4310.1UniSTS
Cytogenetic Map4q22UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001100708 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006236198 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006236200 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008762772 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008762773 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017592611 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017592612 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039107511 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039107512 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039107513 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039107514 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063285982 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063285983 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063285984 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063285985 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BC161956 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473959 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000004 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U27700 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000011851   ⟹   ENSRNOP00000011851
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl458,664,963 - 58,762,301 (+)Ensembl
Rnor_6.0 Ensembl457,378,166 - 57,436,884 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000080173   ⟹   ENSRNOP00000075252
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl458,704,418 - 58,770,665 (+)Ensembl
Rnor_6.0 Ensembl457,378,069 - 57,445,341 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000103272   ⟹   ENSRNOP00000082521
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl458,711,626 - 58,741,228 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000104816   ⟹   ENSRNOP00000079043
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl458,664,957 - 58,769,017 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000105926   ⟹   ENSRNOP00000096374
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl458,664,957 - 58,741,228 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000115640   ⟹   ENSRNOP00000083755
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl458,664,979 - 58,748,363 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000117472   ⟹   ENSRNOP00000094397
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl458,664,957 - 58,762,153 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000118984   ⟹   ENSRNOP00000091041
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl458,711,626 - 58,825,328 (+)Ensembl
RefSeq Acc Id: NM_001100708   ⟹   NP_001094178
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8459,632,426 - 59,729,734 (+)NCBI
mRatBN7.2458,664,990 - 58,762,302 (+)NCBI
Rnor_6.0457,336,665 - 57,436,885 (+)NCBI
Rnor_5.0457,097,471 - 57,207,118 (+)NCBI
RGSC_v3.4456,949,553 - 57,048,149 (+)RGD
Celera453,766,265 - 53,861,921 (+)RGD
Sequence:
RefSeq Acc Id: XM_006236198   ⟹   XP_006236260
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8459,632,366 - 59,738,166 (+)NCBI
mRatBN7.2458,664,932 - 58,772,328 (+)NCBI
Rnor_6.0457,335,735 - 57,445,317 (+)NCBI
Rnor_5.0457,097,471 - 57,207,118 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006236200   ⟹   XP_006236262
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8459,632,366 - 59,738,166 (+)NCBI
mRatBN7.2458,664,932 - 58,772,328 (+)NCBI
Rnor_6.0457,335,734 - 57,445,317 (+)NCBI
Rnor_5.0457,097,471 - 57,207,118 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017592611   ⟹   XP_017448100
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8459,632,366 - 59,729,740 (+)NCBI
mRatBN7.2458,664,932 - 58,762,302 (+)NCBI
Rnor_6.0457,335,733 - 57,436,888 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017592612   ⟹   XP_017448101
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8459,632,366 - 59,729,740 (+)NCBI
mRatBN7.2458,664,932 - 58,762,302 (+)NCBI
Rnor_6.0457,335,732 - 57,436,888 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039107511   ⟹   XP_038963439
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8459,632,366 - 59,738,166 (+)NCBI
mRatBN7.2458,664,932 - 58,772,328 (+)NCBI
RefSeq Acc Id: XM_039107512   ⟹   XP_038963440
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8459,632,366 - 59,722,681 (+)NCBI
mRatBN7.2458,664,932 - 58,749,461 (+)NCBI
RefSeq Acc Id: XM_039107513   ⟹   XP_038963441
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8459,632,366 - 59,729,541 (+)NCBI
mRatBN7.2458,664,932 - 58,762,015 (+)NCBI
RefSeq Acc Id: XM_039107514   ⟹   XP_038963442
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8459,632,366 - 59,722,681 (+)NCBI
mRatBN7.2458,664,932 - 58,749,461 (+)NCBI
RefSeq Acc Id: XM_063285982   ⟹   XP_063142052
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8459,632,366 - 59,729,740 (+)NCBI
RefSeq Acc Id: XM_063285983   ⟹   XP_063142053
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8459,632,366 - 59,738,166 (+)NCBI
RefSeq Acc Id: XM_063285984   ⟹   XP_063142054
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8459,632,366 - 59,738,166 (+)NCBI
RefSeq Acc Id: XM_063285985   ⟹   XP_063142055
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8459,632,366 - 59,722,681 (+)NCBI
RefSeq Acc Id: NP_001094178   ⟸   NM_001100708
- UniProtKB: B1WC04 (UniProtKB/TrEMBL),   A6IEF3 (UniProtKB/TrEMBL),   F7FCI9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006236262   ⟸   XM_006236200
- Peptide Label: isoform X8
- Sequence:
RefSeq Acc Id: XP_006236260   ⟸   XM_006236198
- Peptide Label: isoform X4
- UniProtKB: A6IEF2 (UniProtKB/TrEMBL),   A0A8I6ALN8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017448101   ⟸   XM_017592612
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_017448100   ⟸   XM_017592611
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSRNOP00000075252   ⟸   ENSRNOT00000080173
Ensembl Acc Id: ENSRNOP00000011851   ⟸   ENSRNOT00000011851
RefSeq Acc Id: XP_038963439   ⟸   XM_039107511
- Peptide Label: isoform X3
- UniProtKB: A0A0G2KA43 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038963441   ⟸   XM_039107513
- Peptide Label: isoform X6
- UniProtKB: A0A8I6ALN8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038963440   ⟸   XM_039107512
- Peptide Label: isoform X5
- UniProtKB: A0A8I6ALN8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038963442   ⟸   XM_039107514
- Peptide Label: isoform X7
- UniProtKB: A0A8I5ZWF5 (UniProtKB/TrEMBL),   A0A8I6ALN8 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000096374   ⟸   ENSRNOT00000105926
Ensembl Acc Id: ENSRNOP00000091041   ⟸   ENSRNOT00000118984
Ensembl Acc Id: ENSRNOP00000082521   ⟸   ENSRNOT00000103272
Ensembl Acc Id: ENSRNOP00000079043   ⟸   ENSRNOT00000104816
Ensembl Acc Id: ENSRNOP00000094397   ⟸   ENSRNOT00000117472
Ensembl Acc Id: ENSRNOP00000083755   ⟸   ENSRNOT00000115640
RefSeq Acc Id: XP_063142053   ⟸   XM_063285983
- Peptide Label: isoform X3
- UniProtKB: A0A0G2KA43 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063142054   ⟸   XM_063285984
- Peptide Label: isoform X4
- UniProtKB: A6IEF2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063142052   ⟸   XM_063285982
- Peptide Label: isoform X2
- UniProtKB: A6IEF3 (UniProtKB/TrEMBL),   B1WC04 (UniProtKB/TrEMBL),   F7FCI9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063142055   ⟸   XM_063285985
- Peptide Label: isoform X7
- UniProtKB: A0A8I5ZWF5 (UniProtKB/TrEMBL)
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q62792-F1-model_v2 AlphaFold Q62792 1-52 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1304603 AgrOrtholog
BioCyc Gene G2FUF-45371 BioCyc
Ensembl Genes ENSRNOG00000008752 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000011851.4 UniProtKB/TrEMBL
  ENSRNOT00000080173.2 UniProtKB/TrEMBL
  ENSRNOT00000103272.1 UniProtKB/TrEMBL
  ENSRNOT00000104816.1 UniProtKB/TrEMBL
  ENSRNOT00000105926.1 UniProtKB/TrEMBL
  ENSRNOT00000115640.1 UniProtKB/TrEMBL
  ENSRNOT00000117472.1 UniProtKB/TrEMBL
  ENSRNOT00000118984.1 UniProtKB/TrEMBL
Gene3D-CATH 3.10.20.30 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:9027258 IMAGE-MGC_LOAD
InterPro Beta-grasp_dom UniProtKB/TrEMBL
  DUF933 UniProtKB/TrEMBL
  NRF1/Ewg UniProtKB/TrEMBL
  Nrf1_NLS/DNA-bd_dimer UniProtKB/TrEMBL
  TGS-like UniProtKB/TrEMBL
KEGG Report rno:312195 UniProtKB/TrEMBL
MGC_CLONE MGC:187757 IMAGE-MGC_LOAD
NCBI Gene 312195 ENTREZGENE
PANTHER NUCLEAR RESPIRATORY FACTOR 1 UniProtKB/TrEMBL
  PTHR20338 UniProtKB/TrEMBL
Pfam Nrf1_DNA-bind UniProtKB/TrEMBL
  YchF-GTPase_C UniProtKB/TrEMBL
PhenoGen Nrf1 PhenoGen
RatGTEx ENSRNOG00000008752 RatGTEx
Superfamily-SCOP TGS-like UniProtKB/TrEMBL
UniProt A0A0G2KA43 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZLZ1_RAT UniProtKB/TrEMBL
  A0A8I5ZV29_RAT UniProtKB/TrEMBL
  A0A8I5ZWF5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6ALN8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AN16_RAT UniProtKB/TrEMBL
  A0A8I6APQ0_RAT UniProtKB/TrEMBL
  A6IEF2 ENTREZGENE, UniProtKB/TrEMBL
  A6IEF3 ENTREZGENE, UniProtKB/TrEMBL
  B1WC04 ENTREZGENE
  F7FCI9 ENTREZGENE, UniProtKB/TrEMBL
  NRF1_RAT UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary B1WC04 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Nrf1  nuclear respiratory factor 1   Nrf1_predicted  nuclear respiratory factor 1 (predicted)  'predicted' is removed 2292626 APPROVED
2007-01-31 Nrf1_predicted  nuclear respiratory factor 1 (predicted)  Nfe2l1_retired  nuclear factor (erythroid-derived 2)-like 1  Data merged from RGD:1303265 737654 APPROVED
2007-01-31 Nfe2l1_retired    Nfe2l1  nuclear factor (erythroid-derived 2)-like 1  Symbol updated 1299863 PROVISIONAL
2005-10-12 Nfe2l1        Symbol and Name status set to provisional 70820 PROVISIONAL
2005-01-12 Nrf1_predicted  nuclear respiratory factor 1 (predicted)      Symbol and Name status set to approved 70820 APPROVED