Nrf1 Rat (+)-schisandrin B multiple interactions EXP 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of NRF1 mRNA] CTD PMID:31150632 Nrf1 Rat (R)-noradrenaline multiple interactions EXP 6480464 [Estradiol co-treated with Norepinephrine] results in decreased expression of NRF1 mRNA CTD PMID:16954335 Nrf1 Rat 1-chloro-2,4-dinitrobenzene decreases expression ISO Nrf1 (Mus musculus) 6480464 Dinitrochlorobenzene results in decreased expression of NRF1 mRNA CTD PMID:28219650 Nrf1 Rat 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine decreases expression ISO Nrf1 (Mus musculus) 6480464 1-Methyl-4-phenyl-1 more ... CTD PMID:21856379 Nrf1 Rat 17beta-estradiol multiple interactions ISO NRF1 (Homo sapiens) 6480464 ESR1 protein alternative form inhibits the reaction [Estradiol results in increased expression of NRF1 mRNA] more ... CTD PMID:20302909 and PMID:22105178 Nrf1 Rat 17beta-estradiol increases expression ISO NRF1 (Homo sapiens) 6480464 Estradiol results in increased expression of NRF1 mRNA CTD PMID:20302909 more ... Nrf1 Rat 17beta-estradiol multiple interactions EXP 6480464 [Estradiol co-treated with Norepinephrine] results in decreased expression of NRF1 mRNA CTD PMID:16954335 Nrf1 Rat 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one multiple interactions ISO NRF1 (Homo sapiens) 6480464 1H-(1 more ... CTD PMID:24041027 Nrf1 Rat 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one multiple interactions EXP 6480464 1H-(1 more ... CTD PMID:17179207 Nrf1 Rat 2,2',4,4'-Tetrabromodiphenyl ether decreases expression EXP 6480464 2 more ... CTD PMID:36269211 Nrf1 Rat 2,2',4,4'-Tetrabromodiphenyl ether multiple interactions EXP 6480464 MIR128-1 promotes the reaction [2 more ... CTD PMID:36269211 Nrf1 Rat 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Nrf1 (Mus musculus) 6480464 Tetrachlorodibenzodioxin affects the expression of NRF1 mRNA CTD PMID:21570461 and PMID:24058054 Nrf1 Rat 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO NRF1 (Homo sapiens) 6480464 Tetrachlorodibenzodioxin results in increased expression of NRF1 mRNA CTD PMID:21296121 Nrf1 Rat 2,3-bis(4-hydroxyphenyl)propionitrile increases expression ISO NRF1 (Homo sapiens) 6480464 2 and 3-bis(4-hydroxyphenyl)-propionitrile results in increased expression of NRF1 mRNA CTD PMID:22105178 Nrf1 Rat 2,4-dinitrophenol increases expression ISO Nrf1 (Mus musculus) 6480464 2 and 4-Dinitrophenol results in increased expression of NRF1 mRNA CTD PMID:11784294 Nrf1 Rat 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine affects expression EXP 6480464 Puromycin Aminonucleoside affects the expression of NRF1 mRNA CTD PMID:16609681 Nrf1 Rat 3,4-methylenedioxymethamphetamine increases expression ISO Nrf1 (Mus musculus) 6480464 N-Methyl-3 and 4-methylenedioxyamphetamine results in increased expression of NRF1 mRNA CTD PMID:20188158 Nrf1 Rat 3-isobutyl-1-methyl-7H-xanthine multiple interactions ISO Nrf1 (Mus musculus) 6480464 [licarin A affects the susceptibility to [INS protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone]] which results in increased expression of NRF1 mRNA more ... CTD PMID:29288687 and PMID:32417366 Nrf1 Rat 3-phenylprop-2-enal decreases expression ISO Nrf1 (Mus musculus) 6480464 cinnamaldehyde results in decreased expression of NRF1 mRNA CTD PMID:28219650 Nrf1 Rat 4,4'-diaminodiphenylmethane affects expression ISO Nrf1 (Mus musculus) 6480464 4 and 4'-diaminodiphenylmethane affects the expression of NRF1 mRNA CTD PMID:18648102 Nrf1 Rat 4-hydroxyphenyl retinamide increases expression ISO Nrf1 (Mus musculus) 6480464 Fenretinide results in increased expression of NRF1 mRNA CTD PMID:28973697 Nrf1 Rat 6-propyl-2-thiouracil decreases expression EXP 6480464 Propylthiouracil results in decreased expression of NRF1 mRNA CTD PMID:30047161 Nrf1 Rat 8-bromo-3',5'-cyclic GMP multiple interactions ISO NRF1 (Homo sapiens) 6480464 tin protoporphyrin IX inhibits the reaction [8-bromocyclic GMP results in increased expression of NRF1 mRNA] CTD PMID:24041027 Nrf1 Rat 8-bromo-3',5'-cyclic GMP increases expression ISO NRF1 (Homo sapiens) 6480464 8-bromocyclic GMP results in increased expression of NRF1 mRNA CTD PMID:24041027 Nrf1 Rat acadesine increases expression ISO NRF1 (Homo sapiens) 6480464 acadesine results in increased expression of NRF1 protein CTD PMID:28556920 Nrf1 Rat acadesine multiple interactions ISO NRF1 (Homo sapiens) 6480464 acadesine inhibits the reaction [Isoniazid results in decreased expression of NRF1 protein] CTD PMID:28556920 Nrf1 Rat acetylsalicylic acid multiple interactions ISO Nrf1 (Mus musculus) 6480464 Aspirin inhibits the reaction [Cisplatin results in decreased expression of NRF1 protein] CTD PMID:37179038 Nrf1 Rat acrolein decreases expression EXP 6480464 Acrolein results in decreased expression of NRF1 mRNA CTD PMID:35150775 Nrf1 Rat afimoxifene multiple interactions ISO NRF1 (Homo sapiens) 6480464 fulvestrant inhibits the reaction [afimoxifene results in increased expression of NRF1 mRNA] and Vehicle Emissions inhibits the reaction [afimoxifene results in increased expression of NRF1 mRNA] CTD PMID:22105178 Nrf1 Rat afimoxifene increases expression ISO NRF1 (Homo sapiens) 6480464 afimoxifene results in increased expression of NRF1 mRNA CTD PMID:22105178 Nrf1 Rat aflatoxin B1 increases expression ISO Nrf1 (Mus musculus) 6480464 Aflatoxin B1 results in increased expression of NRF1 mRNA CTD PMID:19770486 Nrf1 Rat aflatoxin B1 increases methylation ISO NRF1 (Homo sapiens) 6480464 Aflatoxin B1 results in increased methylation of NRF1 gene and Aflatoxin B1 results in increased methylation of NRF1 intron CTD PMID:27153756 and PMID:30157460 Nrf1 Rat AICA ribonucleotide multiple interactions EXP 6480464 dorsomorphin inhibits the reaction [AICA ribonucleotide results in increased expression of NRF1 mRNA] CTD PMID:20438809 Nrf1 Rat AICA ribonucleotide increases expression EXP 6480464 AICA ribonucleotide results in increased expression of NRF1 mRNA CTD PMID:20438809 Nrf1 Rat aldehydo-D-glucose multiple interactions EXP 6480464 [Oxygen deficiency co-treated with Glucose deficiency] results in decreased expression of NRF1 protein and qishen yiqi inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in decreased expression of NRF1 protein] CTD PMID:36806343 Nrf1 Rat all-trans-retinoic acid multiple interactions EXP 6480464 Tretinoin inhibits the reaction [monascin inhibits the reaction [Pyruvaldehyde results in increased expression of NRF1 mRNA]] CTD PMID:23331247 Nrf1 Rat alloxan multiple interactions EXP 6480464 Alloxan affects the reaction [imisopasem manganese results in increased expression of NRF1 protein] CTD PMID:28483572 Nrf1 Rat AM-251 multiple interactions ISO Nrf1 (Mus musculus) 6480464 AM 251 inhibits the reaction [Dietary Fats results in decreased expression of NRF1 mRNA] CTD PMID:26847930 Nrf1 Rat amitrole decreases expression EXP 6480464 Amitrole results in decreased expression of NRF1 mRNA CTD PMID:30047161 Nrf1 Rat ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of NRF1 mRNA CTD PMID:16483693 Nrf1 Rat antirheumatic drug increases expression ISO NRF1 (Homo sapiens) 6480464 Antirheumatic Agents results in increased expression of NRF1 mRNA CTD PMID:24449571 Nrf1 Rat arachidonyl-2'-chloroethylamide multiple interactions ISO Nrf1 (Mus musculus) 6480464 FOXO1 protein affects the reaction [arachidonyl-2-chloroethylamide results in decreased expression of NRF1 mRNA] CTD PMID:26847930 Nrf1 Rat arachidonyl-2'-chloroethylamide decreases expression ISO Nrf1 (Mus musculus) 6480464 arachidonyl-2-chloroethylamide results in decreased expression of NRF1 mRNA CTD PMID:26847930 Nrf1 Rat Aroclor 1254 increases expression ISO NRF1 (Homo sapiens) 6480464 Chlorodiphenyl (54% Chlorine) results in increased expression of NRF1 mRNA CTD PMID:16934159 Nrf1 Rat arsane increases expression ISO NRF1 (Homo sapiens) 6480464 Arsenic results in increased expression of NRF1 mRNA CTD PMID:21514422 Nrf1 Rat arsane affects methylation ISO NRF1 (Homo sapiens) 6480464 Arsenic affects the methylation of NRF1 gene CTD PMID:25304211 Nrf1 Rat arsenic atom increases expression ISO NRF1 (Homo sapiens) 6480464 Arsenic results in increased expression of NRF1 mRNA CTD PMID:21514422 Nrf1 Rat arsenic atom affects methylation ISO NRF1 (Homo sapiens) 6480464 Arsenic affects the methylation of NRF1 gene CTD PMID:25304211 Nrf1 Rat arsenous acid affects methylation ISO NRF1 (Homo sapiens) 6480464 Arsenic Trioxide affects the methylation of NRF1 promoter CTD PMID:26046465 Nrf1 Rat atorvastatin calcium multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [Atorvastatin results in increased expression of NRF1 mRNA] and Quercetin inhibits the reaction [Atorvastatin affects the expression of NRF1 mRNA] CTD PMID:21775390 Nrf1 Rat atorvastatin calcium affects expression EXP 6480464 Atorvastatin affects the expression of NRF1 mRNA CTD PMID:21775390 Nrf1 Rat atorvastatin calcium increases expression EXP 6480464 Atorvastatin results in increased expression of NRF1 mRNA CTD PMID:21775390 Nrf1 Rat atrazine increases expression EXP 6480464 Atrazine results in increased expression of NRF1 mRNA CTD PMID:27114639 Nrf1 Rat atrazine decreases expression ISO NRF1 (Homo sapiens) 6480464 Atrazine results in decreased expression of NRF1 mRNA CTD PMID:27114639 Nrf1 Rat benzo[a]pyrene multiple interactions ISO Nrf1 (Mus musculus) 6480464 Benzo(a)pyrene promotes the reaction [AHR protein binds to NRF1 promoter] and Benzo(a)pyrene promotes the reaction [NRF1 protein binds to GSTA1 gene] CTD PMID:11961136 and PMID:19654925 Nrf1 Rat benzo[a]pyrene affects expression EXP 6480464 Benzo(a)pyrene affects the expression of NRF1 mRNA and Benzo(a)pyrene affects the expression of NRF1 protein CTD PMID:32619457 Nrf1 Rat benzo[a]pyrene multiple interactions EXP 6480464 Resveratrol affects the reaction [Benzo(a)pyrene affects the expression of NRF1 mRNA] and Resveratrol affects the reaction [Benzo(a)pyrene affects the expression of NRF1 protein] CTD PMID:32619457 Nrf1 Rat benzo[a]pyrene decreases methylation ISO Nrf1 (Mus musculus) 6480464 Benzo(a)pyrene results in decreased methylation of NRF1 3' UTR and Benzo(a)pyrene results in decreased methylation of NRF1 exon CTD PMID:27901495 Nrf1 Rat benzo[a]pyrene affects methylation ISO NRF1 (Homo sapiens) 6480464 Benzo(a)pyrene affects the methylation of NRF1 5' UTR CTD PMID:27901495 Nrf1 Rat benzo[a]pyrene decreases expression ISO NRF1 (Homo sapiens) 6480464 Benzo(a)pyrene results in decreased expression of NRF1 mRNA and Benzo(a)pyrene results in decreased expression of NRF1 protein CTD PMID:21401886 and PMID:22865514 Nrf1 Rat benzo[a]pyrene multiple interactions ISO NRF1 (Homo sapiens) 6480464 NRF1 mutant form inhibits the reaction [Benzo(a)pyrene results in decreased expression of TFAM protein] and NRF1 mutant form promotes the reaction [Benzo(a)pyrene results in increased abundance of Reactive Oxygen Species] CTD PMID:21401886 Nrf1 Rat benzo[a]pyrene increases expression ISO Nrf1 (Mus musculus) 6480464 Benzo(a)pyrene results in increased expression of NRF1 mRNA CTD PMID:22228805 Nrf1 Rat benzo[a]pyrene diol epoxide I decreases expression ISO NRF1 (Homo sapiens) 6480464 7 more ... CTD PMID:19150397 Nrf1 Rat bis(2-ethylhexyl) phthalate decreases expression ISO NRF1 (Homo sapiens) 6480464 Diethylhexyl Phthalate results in decreased expression of NRF1 mRNA and Diethylhexyl Phthalate results in decreased expression of NRF1 protein CTD PMID:34822940 Nrf1 Rat bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of NRF1 mRNA CTD PMID:25181051 more ... Nrf1 Rat bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of NRF1 mRNA CTD PMID:24105817 Nrf1 Rat Butylbenzyl phthalate decreases expression ISO NRF1 (Homo sapiens) 6480464 butylbenzyl phthalate results in decreased expression of NRF1 mRNA CTD PMID:26520405 Nrf1 Rat Butylbenzyl phthalate decreases expression ISO Nrf1 (Mus musculus) 6480464 butylbenzyl phthalate results in decreased expression of NRF1 mRNA CTD PMID:27923775 Nrf1 Rat cadmium atom increases expression EXP 6480464 Cadmium results in increased expression of NRF1 mRNA CTD PMID:25388156 Nrf1 Rat cadmium dichloride decreases expression EXP 6480464 Cadmium Chloride results in decreased expression of NRF1 mRNA CTD PMID:36493885 Nrf1 Rat cadmium dichloride multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased expression of NRF1 mRNA] CTD PMID:36493885 Nrf1 Rat caffeine decreases expression EXP 6480464 Caffeine results in decreased expression of NRF1 mRNA CTD PMID:20864626 Nrf1 Rat calcitriol increases expression EXP 6480464 Calcitriol results in increased expression of NRF1 protein CTD PMID:30194976 Nrf1 Rat calycosin multiple interactions EXP 6480464 7 more ... CTD PMID:36436616 Nrf1 Rat carbon monoxide multiple interactions ISO Nrf1 (Mus musculus) 6480464 AKT1 protein affects the reaction [Carbon Monoxide results in increased localization of NRF1 protein] and Carbon Monoxide promotes the reaction [NFE2L2 protein binds to NRF1 promoter] CTD PMID:18845810 Nrf1 Rat carbon monoxide increases expression EXP 6480464 Carbon Monoxide results in increased expression of NRF1 protein CTD PMID:17179207 Nrf1 Rat carbon monoxide increases localization ISO Nrf1 (Mus musculus) 6480464 Carbon Monoxide results in increased localization of NRF1 protein CTD PMID:18845810 Nrf1 Rat carbon monoxide multiple interactions EXP 6480464 1H-(1 more ... CTD PMID:17179207 Nrf1 Rat carbon monoxide increases expression ISO Nrf1 (Mus musculus) 6480464 Carbon Monoxide results in increased expression of NRF1 mRNA CTD PMID:17179207 Nrf1 Rat CHIR 99021 decreases expression ISO Nrf1 (Mus musculus) 6480464 Chir 99021 results in decreased expression of NRF1 mRNA CTD PMID:29883716 Nrf1 Rat cisplatin decreases expression ISO Nrf1 (Mus musculus) 6480464 Cisplatin results in decreased expression of NRF1 mRNA and Cisplatin results in decreased expression of NRF1 protein CTD PMID:25270620 and PMID:37179038 Nrf1 Rat cisplatin multiple interactions ISO Nrf1 (Mus musculus) 6480464 Aspirin inhibits the reaction [Cisplatin results in decreased expression of NRF1 protein] CTD PMID:37179038 Nrf1 Rat copper atom increases expression EXP 6480464 Copper deficiency results in increased expression of NRF1 protein CTD PMID:11694003 Nrf1 Rat copper atom decreases response to substance ISO Nrf1 (Mus musculus) 6480464 NRF1 gene results in decreased susceptibility to Copper CTD PMID:24462598 Nrf1 Rat copper atom multiple interactions ISO Nrf1 (Mus musculus) 6480464 NRF1 gene promotes the reaction [Copper results in increased expression of MT1 mRNA] CTD PMID:24462598 Nrf1 Rat copper(0) increases expression EXP 6480464 Copper deficiency results in increased expression of NRF1 protein CTD PMID:11694003 Nrf1 Rat copper(0) decreases response to substance ISO Nrf1 (Mus musculus) 6480464 NRF1 gene results in decreased susceptibility to Copper CTD PMID:24462598 Nrf1 Rat copper(0) multiple interactions ISO Nrf1 (Mus musculus) 6480464 NRF1 gene promotes the reaction [Copper results in increased expression of MT1 mRNA] CTD PMID:24462598 Nrf1 Rat copper(II) sulfate decreases expression ISO NRF1 (Homo sapiens) 6480464 Copper Sulfate results in decreased expression of NRF1 mRNA CTD PMID:19549813 Nrf1 Rat copper(II) sulfate decreases expression ISO Nrf1 (Mus musculus) 6480464 Copper Sulfate results in decreased expression of NRF1 mRNA and Copper Sulfate results in decreased expression of NRF1 protein CTD PMID:38124272 Nrf1 Rat cyclosporin A increases methylation ISO NRF1 (Homo sapiens) 6480464 Cyclosporine results in increased methylation of NRF1 promoter CTD PMID:27989131 Nrf1 Rat cyprodinil increases expression ISO NRF1 (Homo sapiens) 6480464 cyprodinil results in increased expression of NRF1 mRNA CTD PMID:33352482 Nrf1 Rat D-glucose multiple interactions EXP 6480464 [Oxygen deficiency co-treated with Glucose deficiency] results in decreased expression of NRF1 protein and qishen yiqi inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in decreased expression of NRF1 protein] CTD PMID:36806343 Nrf1 Rat dexamethasone multiple interactions ISO Nrf1 (Mus musculus) 6480464 [licarin A affects the susceptibility to [INS protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone]] which results in increased expression of NRF1 mRNA more ... CTD PMID:29288687 and PMID:32417366 Nrf1 Rat Di-n-octyl phthalate decreases expression ISO NRF1 (Homo sapiens) 6480464 di-n-octyl phthalate results in decreased expression of NRF1 mRNA and di-n-octyl phthalate results in decreased expression of NRF1 protein CTD PMID:34822940 Nrf1 Rat diarsenic trioxide affects methylation ISO NRF1 (Homo sapiens) 6480464 Arsenic Trioxide affects the methylation of NRF1 promoter CTD PMID:26046465 Nrf1 Rat Dibutyl phosphate affects expression ISO NRF1 (Homo sapiens) 6480464 di-n-butylphosphoric acid affects the expression of NRF1 mRNA CTD PMID:37042841 Nrf1 Rat dioxygen multiple interactions ISO Nrf1 (Mus musculus) 6480464 [Blood Glucose deficiency co-treated with Oxygen deficiency] results in decreased expression of NRF1 protein and genipin inhibits the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in decreased expression of NRF1 protein] CTD PMID:28477916 Nrf1 Rat dioxygen multiple interactions EXP 6480464 [Oxygen deficiency co-treated with Glucose deficiency] results in decreased expression of NRF1 protein and qishen yiqi inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in decreased expression of NRF1 protein] CTD PMID:36806343 Nrf1 Rat dorsomorphin multiple interactions EXP 6480464 dorsomorphin inhibits the reaction [AICA ribonucleotide results in increased expression of NRF1 mRNA] and dorsomorphin inhibits the reaction [Resveratrol results in increased expression of NRF1 mRNA] CTD PMID:20438809 Nrf1 Rat doxorubicin multiple interactions ISO NRF1 (Homo sapiens) 6480464 3-(2 more ... CTD PMID:28456571 and PMID:29729358 Nrf1 Rat doxorubicin decreases expression ISO NRF1 (Homo sapiens) 6480464 Doxorubicin results in decreased expression of NRF1 protein CTD PMID:28456571 and PMID:29729358 Nrf1 Rat elemental selenium multiple interactions EXP 6480464 NRF1 protein promotes the reaction [Selenium results in increased expression of TFAM mRNA] CTD PMID:17936198 Nrf1 Rat elemental selenium increases expression EXP 6480464 Selenium results in increased expression of NRF1 mRNA CTD PMID:17936198 Nrf1 Rat enalapril increases expression EXP 6480464 Enalapril results in increased expression of NRF1 mRNA CTD PMID:18765277 Nrf1 Rat enniatin decreases expression EXP 6480464 enniatins results in decreased expression of NRF1 mRNA CTD PMID:27163883 Nrf1 Rat enzyme inhibitor multiple interactions ISO NRF1 (Homo sapiens) 6480464 [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of NRF1 protein CTD PMID:23301498 Nrf1 Rat Erythropoietin multiple interactions ISO NRF1 (Homo sapiens) 6480464 Erythropoietin inhibits the reaction [Doxorubicin results in decreased expression of NRF1 protein] and SIRT1 protein affects the reaction [Erythropoietin inhibits the reaction [Doxorubicin results in decreased expression of NRF1 protein]] CTD PMID:28456571 Nrf1 Rat Erythropoietin increases expression ISO NRF1 (Homo sapiens) 6480464 Erythropoietin results in increased expression of NRF1 protein CTD PMID:28456571 Nrf1 Rat ethidium increases expression ISO NRF1 (Homo sapiens) 6480464 Ethidium results in increased expression of NRF1 mRNA CTD PMID:22712077 Nrf1 Rat fenthion decreases expression ISO Nrf1 (Mus musculus) 6480464 Fenthion results in decreased expression of NRF1 mRNA CTD PMID:34813904 Nrf1 Rat fenvalerate increases expression EXP 6480464 fenvalerate results in increased expression of NRF1 mRNA CTD PMID:30307764 Nrf1 Rat fludioxonil increases expression ISO NRF1 (Homo sapiens) 6480464 fludioxonil results in increased expression of NRF1 mRNA CTD PMID:23436777 Nrf1 Rat Flumetralin increases expression ISO NRF1 (Homo sapiens) 6480464 flumetralin results in increased expression of NRF1 mRNA CTD PMID:33352482 Nrf1 Rat formaldehyde decreases expression ISO NRF1 (Homo sapiens) 6480464 Formaldehyde results in decreased expression of NRF1 mRNA CTD PMID:20655997 and PMID:23649840 Nrf1 Rat FR900359 decreases phosphorylation ISO NRF1 (Homo sapiens) 6480464 FR900359 results in decreased phosphorylation of NRF1 protein CTD PMID:37730182 Nrf1 Rat fulvestrant multiple interactions ISO NRF1 (Homo sapiens) 6480464 fulvestrant inhibits the reaction [afimoxifene results in increased expression of NRF1 mRNA] more ... CTD PMID:22105178 Nrf1 Rat gamma-hexachlorocyclohexane increases expression ISO NRF1 (Homo sapiens) 6480464 Hexachlorocyclohexane results in increased expression of NRF1 mRNA CTD PMID:23777605 Nrf1 Rat Genipin multiple interactions ISO Nrf1 (Mus musculus) 6480464 genipin inhibits the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in decreased expression of NRF1 protein] CTD PMID:28477916 Nrf1 Rat Gingerenone A increases expression ISO Nrf1 (Mus musculus) 6480464 gingerenone A results in increased expression of NRF1 mRNA CTD PMID:28556482 Nrf1 Rat glucose multiple interactions EXP 6480464 [Oxygen deficiency co-treated with Glucose deficiency] results in decreased expression of NRF1 protein and qishen yiqi inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in decreased expression of NRF1 protein] CTD PMID:36806343 Nrf1 Rat hemin multiple interactions EXP 6480464 Hemin inhibits the reaction [manganese chloride affects the expression of NRF1 protein] CTD PMID:30040983 Nrf1 Rat hexadecanoic acid multiple interactions ISO Nrf1 (Mus musculus) 6480464 [Oleic Acid co-treated with Palmitic Acid] results in decreased expression of NRF1 mRNA and FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of NRF1 mRNA] CTD PMID:26847930 Nrf1 Rat hydrogen peroxide multiple interactions ISO NRF1 (Homo sapiens) 6480464 resveratrol inhibits the reaction [Hydrogen Peroxide results in decreased expression of NRF1 mRNA] CTD PMID:23859249 Nrf1 Rat hydrogen peroxide affects response to substance ISO NRF1 (Homo sapiens) 6480464 NRF1 protein affects the susceptibility to Hydrogen Peroxide CTD PMID:21051700 Nrf1 Rat hydrogen peroxide affects expression ISO NRF1 (Homo sapiens) 6480464 Hydrogen Peroxide affects the expression of NRF1 mRNA CTD PMID:20044591 Nrf1 Rat hydrogen peroxide decreases expression ISO NRF1 (Homo sapiens) 6480464 Hydrogen Peroxide results in decreased expression of NRF1 mRNA CTD PMID:23859249 Nrf1 Rat indinavir increases expression ISO Nrf1 (Mus musculus) 6480464 Indinavir results in increased expression of NRF1 mRNA CTD PMID:17926646 Nrf1 Rat isoniazide multiple interactions ISO NRF1 (Homo sapiens) 6480464 acadesine inhibits the reaction [Isoniazid results in decreased expression of NRF1 protein] CTD PMID:28556920 Nrf1 Rat isoniazide decreases expression ISO NRF1 (Homo sapiens) 6480464 Isoniazid results in decreased expression of NRF1 protein CTD PMID:28556920 Nrf1 Rat lenvatinib affects expression EXP 6480464 lenvatinib affects the expression of NRF1 mRNA CTD PMID:34019861 Nrf1 Rat Licarin A multiple interactions ISO Nrf1 (Mus musculus) 6480464 [licarin A affects the susceptibility to [INS protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone]] which results in increased expression of NRF1 mRNA CTD PMID:29288687 Nrf1 Rat losartan increases expression EXP 6480464 Losartan results in increased expression of NRF1 mRNA CTD PMID:18765277 Nrf1 Rat LY294002 multiple interactions ISO NRF1 (Homo sapiens) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [cobaltiprotoporphyrin results in increased expression of NRF1 mRNA] and 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [tricarbonylchloro(glycinato)ruthenium(II) results in increased expression of NRF1 mRNA] CTD PMID:24041027 Nrf1 Rat LY294002 multiple interactions EXP 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Carbon Monoxide promotes the reaction [NRF1 protein binds to PPARGC1A protein]] and 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Carbon Monoxide results in increased expression of NRF1 protein] CTD PMID:17179207 Nrf1 Rat manganese(II) chloride multiple interactions EXP 6480464 Hemin inhibits the reaction [manganese chloride affects the expression of NRF1 protein] CTD PMID:30040983 Nrf1 Rat manganese(II) chloride affects expression EXP 6480464 manganese chloride affects the expression of NRF1 protein CTD PMID:30040983 Nrf1 Rat melatonin multiple interactions EXP 6480464 Melatonin inhibits the reaction [Carbon Tetrachloride results in decreased expression of NRF1 protein] CTD PMID:26882442 Nrf1 Rat mepanipyrim increases expression ISO NRF1 (Homo sapiens) 6480464 mepanipyrim results in increased expression of NRF1 mRNA CTD PMID:33352482 Nrf1 Rat metformin increases expression ISO Nrf1 (Mus musculus) 6480464 Metformin results in increased expression of NRF1 mRNA CTD PMID:24428821 Nrf1 Rat metformin increases expression ISO NRF1 (Homo sapiens) 6480464 Metformin results in increased expression of NRF1 mRNA CTD PMID:16380484 Nrf1 Rat methamphetamine increases expression ISO Nrf1 (Mus musculus) 6480464 Methamphetamine results in increased expression of NRF1 mRNA CTD PMID:26307267 Nrf1 Rat methidathion decreases expression ISO Nrf1 (Mus musculus) 6480464 methidathion results in decreased expression of NRF1 mRNA CTD PMID:34813904 Nrf1 Rat methimazole decreases expression EXP 6480464 Methimazole results in decreased expression of NRF1 mRNA CTD PMID:30047161 Nrf1 Rat methoxyacetic acid decreases expression EXP 6480464 methoxyacetic acid results in decreased expression of NRF1 mRNA CTD PMID:20864626 Nrf1 Rat methylglyoxal increases expression EXP 6480464 Pyruvaldehyde results in increased expression of NRF1 mRNA CTD PMID:23331247 Nrf1 Rat methylglyoxal multiple interactions EXP 6480464 monascin inhibits the reaction [Pyruvaldehyde results in increased expression of NRF1 mRNA] more ... CTD PMID:23331247 Nrf1 Rat methylmercury chloride decreases expression EXP 6480464 methylmercuric chloride results in decreased expression of NRF1 mRNA CTD PMID:20864626 Nrf1 Rat mitomycin C decreases expression ISO Nrf1 (Mus musculus) 6480464 Mitomycin results in decreased expression of NRF1 mRNA CTD PMID:25270620 Nrf1 Rat monascin multiple interactions EXP 6480464 monascin inhibits the reaction [Pyruvaldehyde results in increased expression of NRF1 mRNA] and Tretinoin inhibits the reaction [monascin inhibits the reaction [Pyruvaldehyde results in increased expression of NRF1 mRNA]] CTD PMID:23331247 Nrf1 Rat mono(2-ethylhexyl) phthalate affects expression ISO Nrf1 (Mus musculus) 6480464 mono-(2-ethylhexyl)phthalate affects the expression of NRF1 mRNA CTD PMID:32522588 Nrf1 Rat Monobutylphthalate decreases expression EXP 6480464 monobutyl phthalate results in decreased expression of NRF1 mRNA CTD PMID:20864626 Nrf1 Rat monocrotophos multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [Monocrotophos results in decreased expression of NRF1 mRNA] CTD PMID:35403558 Nrf1 Rat monocrotophos decreases expression EXP 6480464 Monocrotophos results in decreased expression of NRF1 mRNA CTD PMID:35403558 Nrf1 Rat N-acetyl-L-cysteine multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [Atorvastatin results in increased expression of NRF1 mRNA] more ... CTD PMID:21775390 more ... Nrf1 Rat N-methyl-4-phenylpyridinium multiple interactions ISO Nrf1 (Mus musculus) 6480464 salvianolic acid B inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of NRF1 mRNA] and salvianolic acid B inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of NRF1 protein] CTD PMID:33994527 Nrf1 Rat N-methyl-4-phenylpyridinium decreases expression ISO Nrf1 (Mus musculus) 6480464 1-Methyl-4-phenylpyridinium results in decreased expression of NRF1 mRNA and 1-Methyl-4-phenylpyridinium results in decreased expression of NRF1 protein CTD PMID:33994527 Nrf1 Rat N-methyl-4-phenylpyridinium decreases expression ISO NRF1 (Homo sapiens) 6480464 1-Methyl-4-phenylpyridinium results in decreased expression of NRF1 mRNA and 1-Methyl-4-phenylpyridinium results in decreased expression of NRF1 protein CTD PMID:26141122 Nrf1 Rat N-methyl-4-phenylpyridinium multiple interactions ISO NRF1 (Homo sapiens) 6480464 PPARGC1A protein inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of NRF1 mRNA] and PPARGC1A protein inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of NRF1 protein] CTD PMID:26141122 Nrf1 Rat nickel atom multiple interactions ISO Nrf1 (Mus musculus) 6480464 [nickel chloride results in increased abundance of Nickel] which results in decreased expression of NRF1 mRNA CTD PMID:36794572 Nrf1 Rat nickel dichloride multiple interactions ISO Nrf1 (Mus musculus) 6480464 [nickel chloride results in increased abundance of Nickel] which results in decreased expression of NRF1 mRNA CTD PMID:36794572 Nrf1 Rat nickel dichloride decreases expression ISO Nrf1 (Mus musculus) 6480464 nickel chloride results in decreased expression of NRF1 mRNA and nickel chloride results in decreased expression of NRF1 protein CTD PMID:38552765 Nrf1 Rat oleic acid multiple interactions ISO Nrf1 (Mus musculus) 6480464 [Oleic Acid co-treated with Palmitic Acid] results in decreased expression of NRF1 mRNA and FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of NRF1 mRNA] CTD PMID:26847930 Nrf1 Rat oxaliplatin multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in decreased expression of NRF1 mRNA CTD PMID:25729387 Nrf1 Rat oxybenzone increases expression EXP 6480464 oxybenzone results in increased expression of NRF1 mRNA CTD PMID:30316929 Nrf1 Rat ozone increases expression ISO Nrf1 (Mus musculus) 6480464 Ozone results in increased expression of NRF1 mRNA CTD PMID:27240593 Nrf1 Rat p-toluidine decreases expression EXP 6480464 4-toluidine results in decreased expression of NRF1 mRNA CTD PMID:27638505 Nrf1 Rat paracetamol increases expression ISO NRF1 (Homo sapiens) 6480464 Acetaminophen results in increased expression of NRF1 mRNA CTD PMID:29067470 Nrf1 Rat paracetamol increases expression ISO Nrf1 (Mus musculus) 6480464 Acetaminophen results in increased expression of NRF1 protein CTD PMID:28827156 and PMID:33271250 Nrf1 Rat perfluorooctane-1-sulfonic acid multiple interactions ISO Nrf1 (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Pectins] results in decreased expression of NRF1 mRNA CTD PMID:36331819 Nrf1 Rat perfluorooctanoic acid increases expression EXP 6480464 perfluorooctanoic acid results in increased expression of NRF1 mRNA CTD PMID:19616056 Nrf1 Rat potassium chloride increases expression EXP 6480464 Potassium Chloride results in increased expression of NRF1 mRNA and Potassium Chloride results in increased expression of NRF1 protein CTD PMID:20438809 Nrf1 Rat pregnenolone 16alpha-carbonitrile decreases expression EXP 6480464 Pregnenolone Carbonitrile results in decreased expression of NRF1 mRNA CTD PMID:30047161 Nrf1 Rat propham increases expression ISO NRF1 (Homo sapiens) 6480464 propham results in increased expression of NRF1 mRNA CTD PMID:33352482 Nrf1 Rat pyrimethanil increases expression ISO NRF1 (Homo sapiens) 6480464 pyrimethanil results in increased expression of NRF1 mRNA CTD PMID:33352482 Nrf1 Rat pyrroloquinoline quinone increases expression ISO NRF1 (Homo sapiens) 6480464 PQQ Cofactor results in increased expression of NRF1 mRNA CTD PMID:28578007 Nrf1 Rat quercetin multiple interactions EXP 6480464 Quercetin inhibits the reaction [aluminum lactate results in decreased expression of NRF1 mRNA] more ... CTD PMID:21775390 and PMID:26493151 Nrf1 Rat raloxifene multiple interactions ISO NRF1 (Homo sapiens) 6480464 fulvestrant inhibits the reaction [Raloxifene Hydrochloride results in increased expression of NRF1 mRNA] and Vehicle Emissions inhibits the reaction [Raloxifene Hydrochloride results in increased expression of NRF1 mRNA] CTD PMID:22105178 Nrf1 Rat raloxifene increases expression ISO NRF1 (Homo sapiens) 6480464 Raloxifene Hydrochloride results in increased expression of NRF1 mRNA CTD PMID:22105178 Nrf1 Rat reactive oxygen species multiple interactions ISO NRF1 (Homo sapiens) 6480464 NRF1 mutant form promotes the reaction [Benzo(a)pyrene results in increased abundance of Reactive Oxygen Species] CTD PMID:21401886 Nrf1 Rat resveratrol multiple interactions ISO NRF1 (Homo sapiens) 6480464 1H-(1 more ... CTD PMID:22105178 more ... Nrf1 Rat resveratrol multiple interactions ISO Nrf1 (Mus musculus) 6480464 [Dietary Fats co-treated with Resveratrol] results in increased expression of NRF1 mRNA more ... CTD PMID:24041027 more ... Nrf1 Rat resveratrol increases expression ISO NRF1 (Homo sapiens) 6480464 resveratrol results in increased expression of NRF1 mRNA CTD PMID:22105178 and PMID:24041027 Nrf1 Rat resveratrol multiple interactions EXP 6480464 dorsomorphin inhibits the reaction [Resveratrol results in increased expression of NRF1 mRNA] more ... CTD PMID:20438809 more ... Nrf1 Rat resveratrol increases expression ISO Nrf1 (Mus musculus) 6480464 Resveratrol results in increased expression of NRF1 mRNA and Resveratrol results in increased expression of NRF1 protein CTD PMID:20561979 more ... Nrf1 Rat resveratrol increases expression EXP 6480464 Resveratrol results in increased expression of NRF1 mRNA and Resveratrol results in increased expression of NRF1 protein CTD PMID:20429690 more ... Nrf1 Rat resveratrol decreases expression ISO Nrf1 (Mus musculus) 6480464 resveratrol results in decreased expression of NRF1 mRNA CTD PMID:21270273 Nrf1 Rat rotenone increases expression ISO Nrf1 (Mus musculus) 6480464 Rotenone results in increased expression of NRF1 mRNA CTD PMID:21536665 Nrf1 Rat rotenone multiple interactions ISO Nrf1 (Mus musculus) 6480464 PPARGC1A protein affects the reaction [Rotenone results in increased expression of NRF1 mRNA] CTD PMID:21536665 Nrf1 Rat salvianolic acid B multiple interactions ISO Nrf1 (Mus musculus) 6480464 salvianolic acid B inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of NRF1 mRNA] and salvianolic acid B inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of NRF1 protein] CTD PMID:33994527 Nrf1 Rat selenium atom multiple interactions EXP 6480464 NRF1 protein promotes the reaction [Selenium results in increased expression of TFAM mRNA] CTD PMID:17936198 Nrf1 Rat selenium atom increases expression EXP 6480464 Selenium results in increased expression of NRF1 mRNA CTD PMID:17936198 Nrf1 Rat sodium arsenite multiple interactions EXP 6480464 sodium arsenite results in decreased expression of and affects the localization of NRF1 protein CTD PMID:27425645 Nrf1 Rat sodium arsenite increases expression ISO NRF1 (Homo sapiens) 6480464 sodium arsenite results in increased expression of NRF1 mRNA CTD PMID:29301061 and PMID:34032870 Nrf1 Rat sodium arsenite affects expression ISO NRF1 (Homo sapiens) 6480464 sodium arsenite affects the expression of NRF1 mRNA CTD PMID:29319823 Nrf1 Rat sodium arsenite decreases expression EXP 6480464 sodium arsenite results in decreased expression of NRF1 mRNA and sodium arsenite results in decreased expression of NRF1 protein CTD PMID:26767369 and PMID:27425645 Nrf1 Rat sodium hydrogensulfite multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [sodium bisulfite results in decreased expression of NRF1 mRNA] CTD PMID:26980303 Nrf1 Rat sodium hydrogensulfite decreases expression EXP 6480464 sodium bisulfite results in decreased expression of NRF1 mRNA and sodium bisulfite results in decreased expression of NRF1 protein CTD PMID:26980303 Nrf1 Rat Soman decreases expression EXP 6480464 Soman results in decreased expression of NRF1 mRNA CTD PMID:19281266 Nrf1 Rat stavudine increases expression ISO Nrf1 (Mus musculus) 6480464 Stavudine results in increased expression of NRF1 mRNA CTD PMID:17926646 Nrf1 Rat sulforaphane increases expression ISO NRF1 (Homo sapiens) 6480464 sulforaphane results in increased expression of NRF1 protein CTD PMID:27993529 Nrf1 Rat sulfur dioxide increases expression EXP 6480464 Sulfur Dioxide results in increased expression of NRF1 protein CTD PMID:22677886 Nrf1 Rat sulfur dioxide decreases expression EXP 6480464 Sulfur Dioxide results in decreased expression of NRF1 mRNA and Sulfur Dioxide results in decreased expression of NRF1 protein CTD PMID:26980303 Nrf1 Rat T-2 toxin multiple interactions ISO NRF1 (Homo sapiens) 6480464 NFE2L2 protein affects the reaction [T-2 Toxin results in decreased expression of NRF1 mRNA] more ... CTD PMID:31470059 and PMID:35842139 Nrf1 Rat T-2 toxin decreases expression ISO NRF1 (Homo sapiens) 6480464 T-2 Toxin results in decreased expression of NRF1 mRNA and T-2 Toxin results in decreased expression of NRF1 protein CTD PMID:35842139 Nrf1 Rat T-2 toxin affects expression EXP 6480464 T-2 Toxin affects the expression of NRF1 mRNA CTD PMID:29870751 Nrf1 Rat T-2 toxin decreases expression ISO Nrf1 (Mus musculus) 6480464 T-2 Toxin results in decreased expression of NRF1 protein CTD PMID:27363784 Nrf1 Rat T-2 toxin multiple interactions ISO Nrf1 (Mus musculus) 6480464 6-hydroxy-2 more ... CTD PMID:27363784 Nrf1 Rat tetrachloromethane multiple interactions EXP 6480464 Melatonin inhibits the reaction [Carbon Tetrachloride results in decreased expression of NRF1 protein] and schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of NRF1 mRNA] CTD PMID:26882442 and PMID:31150632 Nrf1 Rat tetrachloromethane increases expression EXP 6480464 Carbon Tetrachloride results in increased expression of NRF1 mRNA CTD PMID:31150632 Nrf1 Rat tetrachloromethane decreases expression EXP 6480464 Carbon Tetrachloride results in decreased expression of NRF1 protein CTD PMID:26882442 Nrf1 Rat thapsigargin multiple interactions ISO NRF1 (Homo sapiens) 6480464 NRF1 protein inhibits the reaction [Thapsigargin results in decreased phosphorylation of AKT1 protein] CTD PMID:22378314 Nrf1 Rat thapsigargin decreases expression ISO NRF1 (Homo sapiens) 6480464 Thapsigargin results in decreased expression of NRF1 mRNA CTD PMID:22378314 Nrf1 Rat titanium dioxide increases methylation ISO Nrf1 (Mus musculus) 6480464 titanium dioxide results in increased methylation of NRF1 gene CTD PMID:35295148 Nrf1 Rat topotecan multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in decreased expression of NRF1 mRNA CTD PMID:25729387 Nrf1 Rat topotecan decreases expression EXP 6480464 Topotecan results in decreased expression of NRF1 mRNA CTD PMID:25729387 Nrf1 Rat trimellitic anhydride increases expression ISO Nrf1 (Mus musculus) 6480464 trimellitic anhydride results in increased expression of NRF1 mRNA CTD PMID:19042947 Nrf1 Rat Triptolide decreases expression ISO Nrf1 (Mus musculus) 6480464 triptolide results in decreased expression of NRF1 mRNA CTD PMID:29723566 Nrf1 Rat Triptolide decreases expression EXP 6480464 triptolide results in decreased expression of NRF1 mRNA CTD PMID:36436616 Nrf1 Rat Triptolide multiple interactions EXP 6480464 7 more ... CTD PMID:36436616 Nrf1 Rat triptonide affects expression ISO Nrf1 (Mus musculus) 6480464 triptonide affects the expression of NRF1 mRNA CTD PMID:33045310 Nrf1 Rat troglitazone increases expression EXP 6480464 troglitazone results in increased expression of NRF1 mRNA CTD PMID:14563825 Nrf1 Rat tunicamycin decreases expression ISO NRF1 (Homo sapiens) 6480464 Tunicamycin results in decreased expression of NRF1 mRNA CTD PMID:22378314 Nrf1 Rat uranium atom affects expression ISO NRF1 (Homo sapiens) 6480464 Uranium affects the expression of NRF1 mRNA CTD PMID:15672453 Nrf1 Rat urethane increases expression ISO NRF1 (Homo sapiens) 6480464 Urethane results in increased expression of NRF1 mRNA CTD PMID:28818685 Nrf1 Rat valproic acid decreases expression ISO Nrf1 (Mus musculus) 6480464 Valproic Acid results in decreased expression of NRF1 mRNA CTD PMID:21427059 Nrf1 Rat valproic acid decreases expression ISO NRF1 (Homo sapiens) 6480464 Valproic Acid results in decreased expression of NRF1 mRNA CTD PMID:28001369 Nrf1 Rat valproic acid affects expression ISO NRF1 (Homo sapiens) 6480464 Valproic Acid affects the expression of NRF1 mRNA CTD PMID:25979313 Nrf1 Rat zidovudine increases expression ISO Nrf1 (Mus musculus) 6480464 Zidovudine results in increased expression of NRF1 mRNA CTD PMID:17926646 Nrf1 Rat zinc atom multiple interactions ISO NRF1 (Homo sapiens) 6480464 [PCI 5002 co-treated with Zinc] results in increased expression of NRF1 mRNA CTD PMID:18593933 Nrf1 Rat zinc(0) multiple interactions ISO NRF1 (Homo sapiens) 6480464 [PCI 5002 co-treated with Zinc] results in increased expression of NRF1 mRNA CTD PMID:18593933