Tbc1d1 (TBC1 domain family member 1) - Rat Genome Database

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Gene: Tbc1d1 (TBC1 domain family member 1) Rattus norvegicus
Analyze
Symbol: Tbc1d1
Name: TBC1 domain family member 1
RGD ID: 1304562
Description: Predicted to enable GTPase activator activity. Involved in negative regulation of insulin secretion involved in cellular response to glucose stimulus. Orthologous to human TBC1D1 (TBC1 domain family member 1); PARTICIPATES IN insulin responsive facilitative sugar transporter mediated glucose transport pathway; Rab family mediated signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl; atrazine.
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC360937; TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1; TBC1 domain family, member 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: Tbc1d1Tn(sb)1Fkh  
Genetic Models: SD-Tbc1d1Tn(sb)1Fkh
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21443,936,820 - 44,135,133 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1443,935,636 - 44,136,499 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.01445,598,753 - 45,797,650 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1445,598,743 - 45,797,887 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01445,404,208 - 45,603,325 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41446,594,874 - 46,781,813 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11446,598,646 - 46,797,176 (-)NCBI
Celera1443,078,392 - 43,277,032 (-)NCBICelera
Cytogenetic Map14p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
obesity  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Muscle cells engage Rab8A and myosin Vb in insulin-dependent GLUT4 translocation. Ishikura S and Klip A, Am J Physiol Cell Physiol. 2008 Oct;295(4):C1016-25. Epub 2008 Aug 13.
3. Signal transduction meets vesicle traffic: the software and hardware of GLUT4 translocation. Klip A, etal., Am J Physiol Cell Physiol. 2014 May 15;306(10):C879-86. doi: 10.1152/ajpcell.00069.2014. Epub 2014 Mar 5.
4. The Rab-GTPase activating protein, TBC1D1, is critical for maintaining normal glucose homeostasis and β-cell mass. Paglialunga S, etal., Appl Physiol Nutr Metab. 2017 Jun;42(6):647-655. doi: 10.1139/apnm-2016-0585. Epub 2017 Jan 31.
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Ablating the protein TBC1D1 impairs contraction-induced sarcolemmal glucose transporter 4 redistribution but not insulin-mediated responses in rats. Whitfield J, etal., J Biol Chem. 2017 Oct 6;292(40):16653-16664. doi: 10.1074/jbc.M117.806786. Epub 2017 Aug 14.
Additional References at PubMed
PMID:17646400   PMID:19435856   PMID:21799128   PMID:21832089   PMID:24239544   PMID:25931508  


Genomics

Comparative Map Data
Tbc1d1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21443,936,820 - 44,135,133 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1443,935,636 - 44,136,499 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.01445,598,753 - 45,797,650 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1445,598,743 - 45,797,887 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01445,404,208 - 45,603,325 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41446,594,874 - 46,781,813 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11446,598,646 - 46,797,176 (-)NCBI
Celera1443,078,392 - 43,277,032 (-)NCBICelera
Cytogenetic Map14p11NCBI
TBC1D1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38437,891,084 - 38,139,173 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl437,891,084 - 38,139,175 (+)EnsemblGRCh38hg38GRCh38
GRCh37437,892,705 - 38,140,794 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36437,569,115 - 37,817,189 (+)NCBINCBI36Build 36hg18NCBI36
Build 34437,715,285 - 37,963,360NCBI
Celera438,332,894 - 38,580,988 (+)NCBICelera
Cytogenetic Map4p14NCBI
HuRef437,217,333 - 37,465,538 (+)NCBIHuRef
CHM1_1437,891,713 - 38,139,897 (+)NCBICHM1_1
T2T-CHM13v2.0437,860,161 - 38,108,248 (+)NCBIT2T-CHM13v2.0
Tbc1d1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39564,313,648 - 64,508,829 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl564,313,648 - 64,508,829 (+)EnsemblGRCm39 Ensembl
GRCm38564,156,305 - 64,351,486 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl564,156,305 - 64,351,486 (+)EnsemblGRCm38mm10GRCm38
MGSCv37564,551,450 - 64,742,725 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36564,439,443 - 64,629,322 (+)NCBIMGSCv36mm8
Celera561,447,336 - 61,630,472 (+)NCBICelera
Cytogenetic Map5C3.1NCBI
cM Map532.8NCBI
Tbc1d1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554439,046,946 - 9,258,989 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554439,045,312 - 9,270,617 (-)NCBIChiLan1.0ChiLan1.0
TBC1D1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1438,072,187 - 38,320,136 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl438,084,075 - 38,319,842 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0432,217,463 - 32,466,020 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
TBC1D1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1374,077,477 - 74,316,725 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl373,992,452 - 74,316,894 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha376,624,987 - 76,864,200 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0374,858,011 - 75,096,848 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl374,858,008 - 75,097,076 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1374,124,126 - 74,362,638 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0374,270,365 - 74,508,809 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0374,650,619 - 74,889,464 (-)NCBIUU_Cfam_GSD_1.0
Tbc1d1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440528540,209,384 - 40,423,877 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049364825,874,358 - 6,087,474 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TBC1D1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl829,370,481 - 29,590,571 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1829,370,344 - 29,590,574 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2831,012,141 - 31,053,965 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TBC1D1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12712,158,582 - 12,398,414 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2712,156,227 - 12,386,980 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604758,569,944 - 58,810,052 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tbc1d1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248406,592,910 - 6,707,932 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248406,475,382 - 6,709,568 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Tbc1d1
619 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:204
Count of miRNA genes:83
Interacting mature miRNAs:85
Transcripts:ENSRNOT00000002965, ENSRNOT00000029209
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1581500Renag1Renal agenesis QTL 1kidney development trait (VT:0000527)percentage of study population developing unilateral renal agenesis during a period of time (CMO:0000940)14817066868298175Rat
1358296Ael3Aortic elastin QTL 33.70.00051aorta elastin amount (VT:0003905)aortic elastin14826709053267090Rat
2302045Pia39Pristane induced arthritis QTL 394.90.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G2a level (CMO:0002116)14826709053267090Rat
631839Niddm37Non-insulin dependent diabetes mellitus QTL 373.37blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)141103062295876975Rat
2313397Coatc1Coat color QTL1coat/hair pigmentation trait (VT:0010463)coat/hair color measurement (CMO:0001808)141854133263541332Rat
10755459Coatc15Coat color QTL 150.01681coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)141983694464836944Rat
70187Pancm5Pancreatic morphology QTL 516.7pancreas mass (VT:0010144)pancreas weight to body weight ratio (CMO:0000630)143032009280829842Rat
1300154Bp189Blood pressure QTL 1893.04arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)143088377768757901Rat
2313048Bss84Bone structure and strength QTL 843.10.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)143766971982669719Rat
2313084Bss83Bone structure and strength QTL 832.90.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)143766971982669719Rat
2313089Bss81Bone structure and strength QTL 813.40.0001body length (VT:0001256)body length, nose to rump (CMO:0000079)143766971982669719Rat
2313100Bss82Bone structure and strength QTL 8230.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)143766971982669719Rat
738037Hcas6Hepatocarcinoma susceptibility QTL 62.93liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)143905723783368335Rat
70214Niddm28Non-insulin dependent diabetes mellitus QTL 284.06blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)143999825175582726Rat
631523Pia13Pristane induced arthritis QTL 133.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)144079346098037301Rat
1300136Rf22Renal function QTL 223.9renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)144226252995023211Rat

Markers in Region
BI301681  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21444,000,921 - 44,001,091 (+)MAPPERmRatBN7.2
Rnor_6.01445,663,995 - 45,664,164NCBIRnor6.0
Rnor_5.01445,469,364 - 45,469,533UniSTSRnor5.0
RGSC_v3.41446,660,495 - 46,660,664UniSTSRGSC3.4
Celera1443,143,707 - 43,143,876UniSTS
Cytogenetic Map14p11UniSTS
AU046891  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21443,988,017 - 43,988,221 (+)MAPPERmRatBN7.2
Rnor_6.01445,651,125 - 45,651,328NCBIRnor6.0
Rnor_5.01445,456,583 - 45,456,786UniSTSRnor5.0
RGSC_v3.41446,647,278 - 46,647,481UniSTSRGSC3.4
Celera1443,130,791 - 43,130,994UniSTS
Cytogenetic Map14p11UniSTS


Genetic Models
This gene Tbc1d1 is modified in the following models/strains

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 26 15 6 19 6 3 3 74 35 40 11 3
Low 17 42 35 35 5 8 1 5
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000029209   ⟹   ENSRNOP00000033018
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1443,935,636 - 44,059,842 (-)Ensembl
Rnor_6.0 Ensembl1445,598,743 - 45,797,887 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000094490   ⟹   ENSRNOP00000078738
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1443,935,636 - 44,136,499 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000103384   ⟹   ENSRNOP00000079959
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1443,935,636 - 44,136,499 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000113583   ⟹   ENSRNOP00000088613
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1443,935,636 - 44,136,499 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000116025   ⟹   ENSRNOP00000079436
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1443,935,636 - 44,136,499 (-)Ensembl
RefSeq Acc Id: XM_006251004   ⟹   XP_006251066
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21443,936,820 - 44,135,133 (-)NCBI
Rnor_6.01445,598,753 - 45,797,650 (-)NCBI
Rnor_5.01445,404,208 - 45,603,325 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006251005   ⟹   XP_006251067
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21443,936,820 - 44,135,132 (-)NCBI
Rnor_6.01445,598,753 - 45,797,650 (-)NCBI
Rnor_5.01445,404,208 - 45,603,325 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006251006   ⟹   XP_006251068
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21443,936,820 - 44,061,195 (-)NCBI
Rnor_6.01445,598,753 - 45,723,022 (-)NCBI
Rnor_5.01445,404,208 - 45,603,325 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006251007   ⟹   XP_006251069
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21443,936,820 - 44,032,762 (-)NCBI
Rnor_6.01445,598,753 - 45,695,837 (-)NCBI
Rnor_5.01445,404,208 - 45,603,325 (-)NCBI
Sequence:
RefSeq Acc Id: XM_341215   ⟹   XP_341216
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21443,936,820 - 44,135,127 (-)NCBI
Rnor_6.01445,598,753 - 45,797,650 (-)NCBI
Rnor_5.01445,404,208 - 45,603,325 (-)NCBI
RGSC_v3.41446,594,874 - 46,781,813 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs XP_006251066 (Get FASTA)   NCBI Sequence Viewer  
  XP_006251067 (Get FASTA)   NCBI Sequence Viewer  
  XP_006251068 (Get FASTA)   NCBI Sequence Viewer  
  XP_006251069 (Get FASTA)   NCBI Sequence Viewer  
  XP_341216 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_341216   ⟸   XM_341215
- Peptide Label: isoform X3
- UniProtKB: A0A8I6AB45 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006251067   ⟸   XM_006251005
- Peptide Label: isoform X2
- UniProtKB: A0A8I6G5Y5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006251066   ⟸   XM_006251004
- Peptide Label: isoform X1
- UniProtKB: D4AC16 (UniProtKB/TrEMBL),   A0A8I5ZMX5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006251068   ⟸   XM_006251006
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_006251069   ⟸   XM_006251007
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: ENSRNOP00000033018   ⟸   ENSRNOT00000029209
RefSeq Acc Id: ENSRNOP00000078738   ⟸   ENSRNOT00000094490
RefSeq Acc Id: ENSRNOP00000079436   ⟸   ENSRNOT00000116025
RefSeq Acc Id: ENSRNOP00000079959   ⟸   ENSRNOT00000103384
RefSeq Acc Id: ENSRNOP00000088613   ⟸   ENSRNOT00000113583
Protein Domains
PID   Rab-GAP TBC

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4AC16-F1-model_v2 AlphaFold D4AC16 1-1257 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1304562 AgrOrtholog
BioCyc Gene G2FUF-15711 BioCyc
Ensembl Genes ENSRNOG00000002180 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000033018 ENTREZGENE
  ENSRNOP00000033018.5 UniProtKB/TrEMBL
  ENSRNOP00000078738.1 UniProtKB/TrEMBL
  ENSRNOP00000079436 ENTREZGENE
  ENSRNOP00000079436.1 UniProtKB/TrEMBL
  ENSRNOP00000079959 ENTREZGENE
  ENSRNOP00000079959.1 UniProtKB/TrEMBL
  ENSRNOP00000088613 ENTREZGENE
  ENSRNOP00000088613.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000029209 ENTREZGENE
  ENSRNOT00000029209.8 UniProtKB/TrEMBL
  ENSRNOT00000094490.1 UniProtKB/TrEMBL
  ENSRNOT00000103384 ENTREZGENE
  ENSRNOT00000103384.1 UniProtKB/TrEMBL
  ENSRNOT00000113583 ENTREZGENE
  ENSRNOT00000113583.1 UniProtKB/TrEMBL
  ENSRNOT00000116025 ENTREZGENE
  ENSRNOT00000116025.1 UniProtKB/TrEMBL
Gene3D-CATH 2.30.29.30 UniProtKB/TrEMBL
InterPro DUF3350 UniProtKB/TrEMBL
  PH_type UniProtKB/TrEMBL
  PTyr_interaction_dom UniProtKB/TrEMBL
  Rab-GTPase_TBC_sf UniProtKB/TrEMBL
  RabGAP_TBC UniProtKB/TrEMBL
KEGG Report rno:360937 UniProtKB/TrEMBL
NCBI Gene 360937 ENTREZGENE
Pfam DUF3350 UniProtKB/TrEMBL
  PID UniProtKB/TrEMBL
  TBC UniProtKB/TrEMBL
PhenoGen Tbc1d1 PhenoGen
PROSITE PID UniProtKB/TrEMBL
  TBC_RABGAP UniProtKB/TrEMBL
SMART PTB UniProtKB/TrEMBL
  TBC UniProtKB/TrEMBL
Superfamily-SCOP RabGAP_TBC UniProtKB/TrEMBL
UniProt A0A8I5ZLK4_RAT UniProtKB/TrEMBL
  A0A8I5ZMX5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AB45 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6G5Y5 ENTREZGENE, UniProtKB/TrEMBL
  D4AC16 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-11-25 Tbc1d1  TBC1 domain family member 1  Tbc1d1  TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-02-02 Tbc1d1  TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1  Tbc1d1  TBC1 domain family, member 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Tbc1d1  TBC1 domain family, member 1   Tbc1d1_predicted  TBC1 domain family, member 1 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Tbc1d1_predicted  TBC1 domain family, member 1 (predicted)      Symbol and Name status set to approved 70820 APPROVED