Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Atf6b | Rat | 1,2-dimethylhydrazine | increases expression | ISO | Atf6b (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in increased expression of ATF6B mRNA | CTD | PMID:22206623 | Atf6b | Rat | 1H-pyrazole | increases expression | ISO | Atf6b (Mus musculus) | 6480464 | pyrazole results in increased expression of ATF6B mRNA | CTD | PMID:17945193 | Atf6b | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Atf6b (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of ATF6B mRNA | CTD | PMID:24058054 | Atf6b | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of ATF6B mRNA | CTD | PMID:33387578 and PMID:34747641 | Atf6b | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Atf6b (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of ATF6B mRNA | CTD | PMID:21570461 | Atf6b | Rat | 2-hydroxypropanoic acid | increases expression | ISO | ATF6B (Homo sapiens) | 6480464 | Lactic Acid results in increased expression of ATF6B mRNA | CTD | PMID:30851411 | Atf6b | Rat | 4,4'-sulfonyldiphenol | affects methylation | ISO | Atf6b (Mus musculus) | 6480464 | bisphenol S affects the methylation of ATF6B gene | CTD | PMID:31683443 | Atf6b | Rat | 4-hydroxyphenyl retinamide | decreases expression | ISO | Atf6b (Mus musculus) | 6480464 | Fenretinide results in decreased expression of ATF6B mRNA | CTD | PMID:16467112 | Atf6b | Rat | 4-phenylbutyric acid | multiple interactions | EXP | | 6480464 | 4-phenylbutyric acid inhibits the reaction [Methamphetamine results in increased expression of ATF6B protein] | CTD | PMID:34214594 | Atf6b | Rat | acrylamide | decreases expression | ISO | ATF6B (Homo sapiens) | 6480464 | Acrylamide results in decreased expression of ATF6B mRNA | CTD | PMID:32763439 | Atf6b | Rat | amiodarone | increases expression | ISO | ATF6B (Homo sapiens) | 6480464 | Amiodarone results in increased expression of ATF6B mRNA | CTD | PMID:19774075 | Atf6b | Rat | aristolochic acid A | decreases expression | ISO | ATF6B (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of ATF6B mRNA | CTD | PMID:33212167 | Atf6b | Rat | arsane | multiple interactions | ISO | ATF6B (Homo sapiens) | 6480464 | [arsenic trichloride results in increased abundance of Arsenic] promotes the reaction [NFE2L2 protein binds to ATF6B promoter] more ... | CTD | PMID:35625704 | Atf6b | Rat | arsenic atom | multiple interactions | ISO | ATF6B (Homo sapiens) | 6480464 | [arsenic trichloride results in increased abundance of Arsenic] promotes the reaction [NFE2L2 protein binds to ATF6B promoter] more ... | CTD | PMID:35625704 | Atf6b | Rat | arsenic trichloride | multiple interactions | ISO | ATF6B (Homo sapiens) | 6480464 | [arsenic trichloride results in increased abundance of Arsenic] promotes the reaction [NFE2L2 protein binds to ATF6B promoter] more ... | CTD | PMID:35625704 | Atf6b | Rat | arsenous acid | increases expression | ISO | ATF6B (Homo sapiens) | 6480464 | Arsenic Trioxide results in increased expression of ATF6B protein | CTD | PMID:25258189 | Atf6b | Rat | BAPTA | multiple interactions | ISO | ATF6B (Homo sapiens) | 6480464 | 1 more ... | CTD | PMID:28181380 | Atf6b | Rat | BAPTA | increases expression | ISO | ATF6B (Homo sapiens) | 6480464 | 1 more ... | CTD | PMID:28181380 | Atf6b | Rat | benzo[a]pyrene | increases expression | ISO | Atf6b (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of ATF6B mRNA | CTD | PMID:22228805 | Atf6b | Rat | benzo[a]pyrene | affects methylation | ISO | ATF6B (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of ATF6B promoter | CTD | PMID:27901495 | Atf6b | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of ATF6B mRNA | CTD | PMID:30816183 more ... | Atf6b | Rat | bisphenol A | affects methylation | ISO | ATF6B (Homo sapiens) | 6480464 | bisphenol A affects the methylation of ATF6B gene | CTD | PMID:31601247 | Atf6b | Rat | bisphenol A | affects methylation | ISO | Atf6b (Mus musculus) | 6480464 | bisphenol A affects the methylation of ATF6B promoter | CTD | PMID:27334623 | Atf6b | Rat | cadmium atom | multiple interactions | ISO | ATF6B (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of ATF6B mRNA | CTD | PMID:35301059 | Atf6b | Rat | cadmium dichloride | decreases methylation | EXP | | 6480464 | Cadmium Chloride results in decreased methylation of ATF6B promoter | CTD | PMID:22457795 | Atf6b | Rat | cadmium dichloride | multiple interactions | ISO | ATF6B (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of ATF6B mRNA | CTD | PMID:35301059 | Atf6b | Rat | cadmium dichloride | increases expression | ISO | ATF6B (Homo sapiens) | 6480464 | Cadmium Chloride results in increased expression of ATF6B mRNA | CTD | PMID:38382870 | Atf6b | Rat | choline | multiple interactions | ISO | Atf6b (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of ATF6B gene | CTD | PMID:20938992 | Atf6b | Rat | cisplatin | multiple interactions | ISO | ATF6B (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in increased expression of ATF6B mRNA | CTD | PMID:27392435 | Atf6b | Rat | diarsenic trioxide | increases expression | ISO | ATF6B (Homo sapiens) | 6480464 | Arsenic Trioxide results in increased expression of ATF6B protein | CTD | PMID:25258189 | Atf6b | Rat | dicrotophos | increases expression | ISO | ATF6B (Homo sapiens) | 6480464 | dicrotophos results in increased expression of ATF6B mRNA | CTD | PMID:28302478 | Atf6b | Rat | endosulfan | increases expression | EXP | | 6480464 | Endosulfan results in increased expression of ATF6B mRNA | CTD | PMID:29391264 | Atf6b | Rat | ethanol | affects expression | ISO | Atf6b (Mus musculus) | 6480464 | Ethanol affects the expression of ATF6B mRNA | CTD | PMID:30319688 | Atf6b | Rat | fenthion | decreases expression | ISO | Atf6b (Mus musculus) | 6480464 | Fenthion results in decreased expression of ATF6B mRNA | CTD | PMID:34813904 | Atf6b | Rat | fisetin | multiple interactions | ISO | ATF6B (Homo sapiens) | 6480464 | 1 more ... | CTD | PMID:28181380 | Atf6b | Rat | fisetin | increases expression | ISO | ATF6B (Homo sapiens) | 6480464 | fisetin results in increased expression of ATF6B protein | CTD | PMID:28181380 | Atf6b | Rat | folic acid | affects expression | ISO | ATF6B (Homo sapiens) | 6480464 | Folic Acid affects the expression of ATF6B mRNA | CTD | PMID:17320366 | Atf6b | Rat | folic acid | multiple interactions | ISO | Atf6b (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of ATF6B gene | CTD | PMID:20938992 | Atf6b | Rat | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of ATF6B mRNA | CTD | PMID:33387578 | Atf6b | Rat | hydroquinone O-beta-D-glucopyranoside | decreases expression | ISO | ATF6B (Homo sapiens) | 6480464 | Arbutin results in decreased expression of ATF6B mRNA | CTD | PMID:17103032 | Atf6b | Rat | kojic acid | decreases expression | ISO | ATF6B (Homo sapiens) | 6480464 | kojic acid results in decreased expression of ATF6B mRNA | CTD | PMID:16595896 | Atf6b | Rat | L-methionine | multiple interactions | ISO | Atf6b (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of ATF6B gene | CTD | PMID:20938992 | Atf6b | Rat | L-serine | increases expression | ISO | ATF6B (Homo sapiens) | 6480464 | Serine results in increased expression of ATF6B mRNA | CTD | PMID:29098664 | Atf6b | Rat | methamphetamine | multiple interactions | EXP | | 6480464 | 4-phenylbutyric acid inhibits the reaction [Methamphetamine results in increased expression of ATF6B protein] | CTD | PMID:34214594 | Atf6b | Rat | methamphetamine | increases expression | EXP | | 6480464 | Methamphetamine results in increased expression of ATF6B protein | CTD | PMID:34214594 | Atf6b | Rat | methotrexate | increases expression | ISO | ATF6B (Homo sapiens) | 6480464 | Methotrexate results in increased expression of ATF6B mRNA | CTD | PMID:24449571 | Atf6b | Rat | Nonidet P-40 | increases expression | ISO | ATF6B (Homo sapiens) | 6480464 | Nonidet P-40 results in increased expression of ATF6B mRNA | CTD | PMID:26552463 | Atf6b | Rat | ouabain | increases expression | ISO | ATF6B (Homo sapiens) | 6480464 | Ouabain results in increased expression of ATF6B protein | CTD | PMID:31436044 | Atf6b | Rat | ozone | decreases expression | ISO | Atf6b (Mus musculus) | 6480464 | Ozone results in decreased expression of ATF6B mRNA | CTD | PMID:12763052 | Atf6b | Rat | ozone | increases expression | ISO | ATF6B (Homo sapiens) | 6480464 | Ozone results in increased expression of ATF6B mRNA | CTD | PMID:27206323 | Atf6b | Rat | paracetamol | decreases expression | ISO | ATF6B (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of ATF6B mRNA | CTD | PMID:29067470 | Atf6b | Rat | perfluorohexanesulfonic acid | increases expression | ISO | Atf6b (Mus musculus) | 6480464 | perfluorohexanesulfonic acid results in increased expression of ATF6B mRNA | CTD | PMID:37995155 | Atf6b | Rat | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Atf6b (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Pectins] results in decreased expression of ATF6B mRNA | CTD | PMID:36331819 | Atf6b | Rat | pirinixic acid | multiple interactions | ISO | Atf6b (Mus musculus) | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of ATF6B mRNA | CTD | PMID:19710929 | Atf6b | Rat | quercetin | increases expression | ISO | ATF6B (Homo sapiens) | 6480464 | Quercetin results in increased expression of ATF6B protein | CTD | PMID:30152185 | Atf6b | Rat | rac-lactic acid | increases expression | ISO | ATF6B (Homo sapiens) | 6480464 | Lactic Acid results in increased expression of ATF6B mRNA | CTD | PMID:30851411 | Atf6b | Rat | testosterone | decreases expression | ISO | Atf6b (Mus musculus) | 6480464 | Testosterone results in decreased expression of ATF6B mRNA | CTD | PMID:15788153 | Atf6b | Rat | tetrachloromethane | increases expression | ISO | Atf6b (Mus musculus) | 6480464 | Carbon Tetrachloride results in increased expression of ATF6B mRNA | CTD | PMID:27339419 and PMID:31919559 | Atf6b | Rat | thiram | decreases expression | ISO | ATF6B (Homo sapiens) | 6480464 | Thiram results in decreased expression of ATF6B mRNA | CTD | PMID:38568856 | Atf6b | Rat | titanium dioxide | increases methylation | ISO | Atf6b (Mus musculus) | 6480464 | titanium dioxide results in increased methylation of ATF6B gene | CTD | PMID:35295148 | Atf6b | Rat | trichloroethene | increases methylation | EXP | | 6480464 | Trichloroethylene results in increased methylation of ATF6B gene | CTD | PMID:27618143 | Atf6b | Rat | triphenyl phosphate | affects expression | ISO | ATF6B (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of ATF6B mRNA | CTD | PMID:37042841 | Atf6b | Rat | Triptolide | decreases expression | ISO | Atf6b (Mus musculus) | 6480464 | triptolide results in decreased expression of ATF6B protein | CTD | PMID:26990902 | Atf6b | Rat | valproic acid | affects expression | ISO | Atf6b (Mus musculus) | 6480464 | Valproic Acid affects the expression of ATF6B mRNA | CTD | PMID:17963808 | Atf6b | Rat | valproic acid | decreases methylation | ISO | ATF6B (Homo sapiens) | 6480464 | Valproic Acid results in decreased methylation of ATF6B gene | CTD | PMID:29154799 | Atf6b | Rat | vinclozolin | decreases expression | EXP | | 6480464 | vinclozolin results in decreased expression of ATF6B mRNA | CTD | PMID:23034163 | |