Pard6a (par-6 family cell polarity regulator alpha) - Rat Genome Database

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Gene: Pard6a (par-6 family cell polarity regulator alpha) Rattus norvegicus
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Symbol: Pard6a
Name: par-6 family cell polarity regulator alpha
RGD ID: 1303273
Description: Predicted to enable GTP-dependent protein binding activity and small GTPase binding activity. Involved in regulation of cellular localization. Located in axonal growth cone and neuronal cell body. Part of protein-containing complex. Orthologous to human PARD6A (par-6 family cell polarity regulator alpha); PARTICIPATES IN adenosine signaling pathway; insulin signaling pathway; protein kinase C (PKC) signaling pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: par-6 (partitioning defective 6,) homolog alpha; par-6 (partitioning defective 6,) homolog alpha (C. elegans); PAR-6 alpha; Par-6a; Par6a; partitioning defective 6 homolog alpha; partitioning defective protein 6A
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81950,499,420 - 50,502,301 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1950,499,442 - 50,502,674 (+)EnsemblGRCr8
mRatBN7.21933,589,531 - 33,591,900 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1933,589,542 - 33,591,900 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1940,405,102 - 40,407,471 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01941,058,434 - 41,060,803 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01943,356,207 - 43,358,576 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01937,668,133 - 37,670,450 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1937,668,133 - 37,672,729 (+)Ensemblrn6Rnor6.0
Rnor_5.01948,534,837 - 48,537,154 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41935,533,395 - 35,535,711 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1933,017,530 - 33,019,847 (+)NCBICelera
RGSC_v3.11935,538,275 - 35,540,592 (+)NCBI
Cytogenetic Map19q12NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Cdc42 regulates GSK-3beta and adenomatous polyposis coli to control cell polarity. Etienne-Manneville S and Hall A, Nature 2003 Feb 13;421(6924):753-6.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
6. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. LIMK1 regulates Golgi dynamics, traffic of Golgi-derived vesicles, and process extension in primary cultured neurons. Rosso S, etal., Mol Biol Cell. 2004 Jul;15(7):3433-49. Epub 2004 Apr 16.
10. The PAR-aPKC system: lessons in polarity. Suzuki A and Ohno S, J Cell Sci. 2006 Mar 15;119(Pt 6):979-87.
11. Protein kinase Czeta and glycogen synthase kinase-3beta control neuronal polarity in developing rodent enteric neurons, whereas SMAD specific E3 ubiquitin protein ligase 1 promotes neurite growth but does not influence polarity. Vohra BP, etal., J Neurosci. 2007 Aug 29;27(35):9458-68.
12. Par3/Par6 polarity complex coordinates apical ectoplasmic specialization and blood-testis barrier restructuring during spermatogenesis. Wong EW, etal., Proc Natl Acad Sci U S A. 2008 Jul 15;105(28):9657-62. Epub 2008 Jul 10.
Additional References at PubMed
PMID:10954424   PMID:12813044   PMID:14685273   PMID:15028215   PMID:15723051   PMID:16510873   PMID:18267090   PMID:19620967   PMID:20719959   PMID:21262463   PMID:24305805   PMID:24312324  
PMID:25948265   PMID:27044754   PMID:28848997   PMID:29155179  


Genomics

Comparative Map Data
Pard6a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81950,499,420 - 50,502,301 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1950,499,442 - 50,502,674 (+)EnsemblGRCr8
mRatBN7.21933,589,531 - 33,591,900 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1933,589,542 - 33,591,900 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1940,405,102 - 40,407,471 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01941,058,434 - 41,060,803 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01943,356,207 - 43,358,576 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01937,668,133 - 37,670,450 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1937,668,133 - 37,672,729 (+)Ensemblrn6Rnor6.0
Rnor_5.01948,534,837 - 48,537,154 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41935,533,395 - 35,535,711 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1933,017,530 - 33,019,847 (+)NCBICelera
RGSC_v3.11935,538,275 - 35,540,592 (+)NCBI
Cytogenetic Map19q12NCBI
PARD6A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381667,660,960 - 67,662,774 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1667,660,946 - 67,662,774 (+)Ensemblhg38GRCh38
GRCh371667,694,863 - 67,696,677 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361666,252,352 - 66,254,182 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341666,252,362 - 66,254,177NCBI
Celera1652,203,341 - 52,205,171 (+)NCBICelera
Cytogenetic Map16q22.1NCBI
HuRef1653,567,763 - 53,569,593 (+)NCBIHuRef
CHM1_11669,102,564 - 69,104,394 (+)NCBICHM1_1
T2T-CHM13v2.01673,455,728 - 73,457,542 (+)NCBIT2T-CHM13v2.0
Pard6a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398106,427,780 - 106,430,126 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl8106,427,780 - 106,430,128 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm388105,701,148 - 105,703,494 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8105,701,148 - 105,703,496 (+)Ensemblmm10GRCm38
MGSCv378108,225,054 - 108,227,394 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv368108,590,812 - 108,592,595 (+)NCBIMGSCv36mm8
Celera8109,926,072 - 109,928,412 (+)NCBICelera
Cytogenetic Map8D3NCBI
cM Map853.04NCBI
Pard6a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554849,019,929 - 9,021,995 (-)Ensembl
ChiLan1.0NW_0049554849,019,929 - 9,022,561 (-)NCBIChiLan1.0ChiLan1.0
PARD6A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21877,189,120 - 77,190,952 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11683,101,588 - 83,103,415 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01648,004,822 - 48,006,656 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11667,394,252 - 67,395,991 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1667,394,252 - 67,395,991 (+)EnsemblpanPan2panpan1.1
PARD6A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1581,787,424 - 81,789,833 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl581,787,553 - 81,790,324 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha581,777,186 - 81,779,574 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0582,222,592 - 82,224,980 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl582,222,721 - 82,225,620 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1582,048,921 - 82,051,309 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0581,730,456 - 81,732,843 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0582,373,005 - 82,375,393 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Pard6a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934941,533,814 - 41,536,924 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647518,052,181 - 18,054,620 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493647518,052,768 - 18,054,620 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PARD6A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl628,280,502 - 28,283,788 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1628,280,502 - 28,282,923 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
PARD6A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1559,781,890 - 59,783,990 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604722,535,640 - 22,537,747 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pard6a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474618,686,921 - 18,688,703 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462474618,686,916 - 18,688,739 (-)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in Pard6a
4 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:43
Count of miRNA genes:40
Interacting mature miRNAs:43
Transcripts:ENSRNOT00000044971
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61447Tcas1Tongue tumor susceptibility QTL 16.08tongue integrity trait (VT:0010553)squamous cell carcinoma of the tongue maximum tumor diameter (CMO:0001875)19231612147316121Rat
9590298Uminl5Urine mineral level QTL 53.590.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)19136824771Rat
724546Kidm3Kidney mass QTL 33.1kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)192932249057337602Rat
1331737Uae29Urinary albumin excretion QTL 295.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19409615555283277Rat
2298478Eau8Experimental allergic uveoretinitis QTL 80.0163uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)191715443357337602Rat
1578764Stresp19Stress response QTL 193.60.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)191563020157337602Rat
1558656Prcs1Prostate cancer susceptibility QTL 15prostate integrity trait (VT:0010571)percentage of study population developing ventral prostate tumorous lesions during a period of time (CMO:0000943)191511459834521833Rat
9590090Insglur8Insulin/glucose ratio QTL 810.810.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)19136824771Rat
1331788Rf45Renal function QTL 452.818kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)191560502346559041Rat
1549835Tcas7Tongue tumor susceptibility QTL 70.001tongue integrity trait (VT:0010553)squamous cell carcinoma of the head and neck tumor number (CMO:0001876)192481797839654489Rat
724566Uae12Urinary albumin excretion QTL 125urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19218792756457239Rat
1354633Bw28Body weight QTL 286.04body mass (VT:0001259)body weight (CMO:0000012)192753020737947399Rat
724565Tcas5Tongue tumor susceptibility QTL 510.04tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)19997775339654489Rat
8552935Pigfal10Plasma insulin-like growth factor 1 level QTL 105.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)19136824771Rat
61350Bp32Blood pressure QTL 320.012arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)192048357557337602Rat
7411549Bw130Body weight QTL 13050.001body mass (VT:0001259)body weight gain (CMO:0000420)191545586057337602Rat
724518Uae19Urinary albumin excretion QTL 195.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)19745724942983518Rat
8694186Bw152Body weight QTL 1523.340.001body mass (VT:0001259)body weight gain (CMO:0000420)1956937445569374Rat
61423Cia14Collagen induced arthritis QTL 143joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)191082797043544039Rat
9590250Scort11Serum corticosterone level QTL 1123.450.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)19136824771Rat
2317848Alcrsp21Alcohol response QTL 211.8999999761581420.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)19320477748204777Rat
1354607Gmadr1Adrenal mass QTL 15.83adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)192753020737947399Rat
9589102Slep13Serum leptin concentration QTL 134.630.001blood leptin amount (VT:0005667)plasma leptin level (CMO:0000781)1956937445569374Rat
7247442Uae39Urinary albumin excretion QTL 39urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)19218792746708701Rat
1354600Salc2Saline consumption QTL 29.910.001drinking behavior trait (VT:0001422)saline drink intake rate (CMO:0001627)192753020737947399Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 159 91 90 59 84 59 6 343 181 8 141 79 91 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000044971   ⟹   ENSRNOP00000043456
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1950,499,442 - 50,501,789 (+)Ensembl
mRatBN7.2 Ensembl1933,589,542 - 33,591,898 (+)Ensembl
Rnor_6.0 Ensembl1937,668,133 - 37,670,449 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000084970   ⟹   ENSRNOP00000069044
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1937,668,693 - 37,672,729 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000114562   ⟹   ENSRNOP00000091863
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1950,499,958 - 50,502,674 (+)Ensembl
mRatBN7.2 Ensembl1933,590,122 - 33,591,900 (+)Ensembl
RefSeq Acc Id: NM_001003653   ⟹   NP_001003653
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81950,499,958 - 50,501,789 (+)NCBI
mRatBN7.21933,590,069 - 33,591,900 (+)NCBI
Rnor_6.01937,668,672 - 37,670,450 (+)NCBI
Rnor_5.01948,534,837 - 48,537,154 (+)NCBI
RGSC_v3.41935,533,395 - 35,535,711 (+)RGD
Celera1933,018,069 - 33,019,847 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001003654   ⟹   NP_001003654
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81950,499,420 - 50,501,789 (+)NCBI
mRatBN7.21933,589,531 - 33,591,900 (+)NCBI
Rnor_6.01937,668,133 - 37,670,450 (+)NCBI
Rnor_5.01948,534,837 - 48,537,154 (+)NCBI
RGSC_v3.41935,533,395 - 35,535,711 (+)RGD
Celera1933,017,530 - 33,019,847 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001399176   ⟹   NP_001386105
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81950,499,958 - 50,501,789 (+)NCBI
mRatBN7.21933,590,069 - 33,591,900 (+)NCBI
RefSeq Acc Id: XM_063278023   ⟹   XP_063134093
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81950,499,450 - 50,502,301 (+)NCBI
RefSeq Acc Id: NP_001003654   ⟸   NM_001003654
- Peptide Label: isoform 2
- UniProtKB: F1LPM7 (UniProtKB/TrEMBL),   A6IYR9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001003653   ⟸   NM_001003653
- Peptide Label: isoform 1
- UniProtKB: Q6B4M6 (UniProtKB/Swiss-Prot),   Q6B4M5 (UniProtKB/Swiss-Prot),   Q4U4X0 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSRNOP00000069044   ⟸   ENSRNOT00000084970
Ensembl Acc Id: ENSRNOP00000043456   ⟸   ENSRNOT00000044971
Ensembl Acc Id: ENSRNOP00000091863   ⟸   ENSRNOT00000114562
RefSeq Acc Id: NP_001386105   ⟸   NM_001399176
- Peptide Label: isoform 3
- UniProtKB: Q6B4M6 (UniProtKB/Swiss-Prot),   Q6B4M5 (UniProtKB/Swiss-Prot),   Q4U4X0 (UniProtKB/Swiss-Prot),   A0A8I6AFC2 (UniProtKB/TrEMBL),   A6IYR8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063134093   ⟸   XM_063278023
- Peptide Label: isoform X1
- UniProtKB: A6IYR9 (UniProtKB/TrEMBL),   F1LPM7 (UniProtKB/TrEMBL)
Protein Domains
PB1   PDZ   Pseudo-CRIB

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6B4M5-F1-model_v2 AlphaFold Q6B4M5 1-346 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701084
Promoter ID:EPDNEW_R11608
Type:single initiation site
Name:Pard6a_1
Description:par-6 family cell polarity regulator alpha
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01937,668,738 - 37,668,798EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1303273 AgrOrtholog
BioCyc Gene G2FUF-5817 BioCyc
Ensembl Genes ENSRNOG00000017746 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000114562 ENTREZGENE
Gene3D-CATH 2.30.42.10 UniProtKB/Swiss-Prot
  Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1 UniProtKB/Swiss-Prot
InterPro PAR6_homolog UniProtKB/Swiss-Prot
  PB1-like UniProtKB/Swiss-Prot
  PB1_dom UniProtKB/Swiss-Prot
  PB1_Par6 UniProtKB/Swiss-Prot
  PDZ UniProtKB/Swiss-Prot
  PDZ_sf UniProtKB/Swiss-Prot
NCBI Gene 307799 ENTREZGENE
PANTHER PAR-6-RELATED UniProtKB/Swiss-Prot
  PTHR14102:SF9 UniProtKB/Swiss-Prot
Pfam PB1 UniProtKB/Swiss-Prot
  PDZ UniProtKB/Swiss-Prot
PhenoGen Pard6a PhenoGen
PROSITE PB1 UniProtKB/Swiss-Prot
  PDZ UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000017746 RatGTEx
SMART PB1 UniProtKB/Swiss-Prot
  PDZ UniProtKB/Swiss-Prot
Superfamily-SCOP CAD & PB1 domains UniProtKB/Swiss-Prot
  SSF50156 UniProtKB/Swiss-Prot
UniProt A0A8I6AFC2 ENTREZGENE, UniProtKB/TrEMBL
  A6IYR8 ENTREZGENE, UniProtKB/TrEMBL
  A6IYR9 ENTREZGENE, UniProtKB/TrEMBL
  F1LPM7 ENTREZGENE, UniProtKB/TrEMBL
  PAR6A_RAT UniProtKB/Swiss-Prot
  Q4U4X0 ENTREZGENE
  Q6B4M5 ENTREZGENE
  Q6B4M6 ENTREZGENE
UniProt Secondary Q4U4X0 UniProtKB/Swiss-Prot
  Q6B4M6 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-11-19 Pard6a  par-6 family cell polarity regulator alpha  Pard6a  par-6 (partitioning defective 6,) homolog alpha (C. elegans)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Pard6a  par-6 (partitioning defective 6,) homolog alpha (C. elegans)  Par-6a    Symbol updated 1299863 APPROVED
2005-09-30 Par-6a        Symbol and Name status set to provisional 70820 PROVISIONAL