Tacc3 (transforming, acidic coiled-coil containing protein 3) - Rat Genome Database

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Gene: Tacc3 (transforming, acidic coiled-coil containing protein 3) Rattus norvegicus
Analyze
Symbol: Tacc3
Name: transforming, acidic coiled-coil containing protein 3
RGD ID: 1302948
Description: Predicted to enable protein domain specific binding activity. Predicted to be involved in several processes, including cerebral cortex development; microtubule cytoskeleton organization involved in mitosis; and regulation of cell cycle process. Predicted to act upstream of or within several processes, including astral microtubule organization; nervous system development; and response to hypoxia. Predicted to be located in Golgi apparatus; cytosol; and microtubule cytoskeleton. Predicted to be active in cytoplasm; glutamatergic synapse; and postsynaptic density. Orthologous to human TACC3 (transforming acidic coiled-coil containing protein 3); PARTICIPATES IN RNA transport pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: transforming acidic coiled coil 3; transforming acidic coiled-coil-containing protein 3
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81481,275,755 - 81,289,894 (-)NCBIGRCr8
GRCr8 Ensembl1481,275,755 - 81,289,698 (-)EnsemblGRCr8 Ensembl
mRatBN7.21477,051,209 - 77,065,343 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1477,051,215 - 77,065,219 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1481,503,501 - 81,517,450 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01482,744,101 - 82,758,050 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01479,189,401 - 79,203,350 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01482,336,283 - 82,350,069 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1482,336,324 - 82,347,679 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01483,025,668 - 83,039,454 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41482,746,460 - 82,760,864 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1475,974,760 - 75,988,702 (-)NCBICelera
RGSC_v3.11482,748,850 - 82,763,255 (-)NCBI
Cytogenetic Map14q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,1-dichloroethene  (ISO)
1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene  (ISO)
1,2-dimethylhydrazine  (ISO)
1-naphthyl isothiocyanate  (EXP)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (EXP)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3',4,4',5-Pentachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,4'-trichlorobiphenyl  (ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2-amino-2-deoxy-D-glucopyranose  (EXP)
2-palmitoylglycerol  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3,4-methylenedioxymethamphetamine  (ISO)
4-hydroxynon-2-enal  (ISO)
6-propyl-2-thiouracil  (EXP)
Abemaciclib  (ISO)
acetamide  (EXP)
acetylsalicylic acid  (ISO)
acrolein  (ISO)
aflatoxin B1  (EXP,ISO)
aldehydo-D-glucosamine  (EXP)
alpha-pinene  (ISO)
AM-251  (ISO)
antimycin A  (ISO)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
Aroclor 1254  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
azoxystrobin  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[b]fluoranthene  (ISO)
beta-D-glucosamine  (EXP)
beta-lapachone  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bisphenol A  (EXP,ISO)
caffeine  (ISO)
calcitriol  (ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
chlorpyrifos  (ISO)
choline  (ISO)
chromium(6+)  (ISO)
cisplatin  (ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
corosolic acid  (ISO)
coumarin  (ISO)
coumestrol  (ISO)
cyclosporin A  (ISO)
decabromodiphenyl ether  (EXP)
deguelin  (ISO)
diallyl trisulfide  (ISO)
diazinon  (EXP)
dibenz[a,h]anthracene  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (ISO)
dichloroacetic acid  (ISO)
diethyl malate  (ISO)
diethylstilbestrol  (EXP)
dioxygen  (ISO)
dorsomorphin  (ISO)
endosulfan  (EXP)
Enterolactone  (ISO)
enzyme inhibitor  (ISO)
fenpyroximate  (ISO)
folic acid  (ISO)
FR900359  (ISO)
gallic acid  (ISO)
genistein  (ISO)
hydrogen peroxide  (ISO)
ivermectin  (ISO)
L-methionine  (ISO)
lead(0)  (ISO)
leflunomide  (ISO)
lidocaine  (EXP)
methotrexate  (ISO)
methylmercury chloride  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
monobenzyl phthalate  (ISO)
Monobutylphthalate  (ISO)
monoethyl phthalate  (ISO)
N-Nitrosopyrrolidine  (ISO)
niclosamide  (ISO)
okadaic acid  (ISO)
oxaliplatin  (EXP)
ozone  (ISO)
paclitaxel  (ISO)
palbociclib  (ISO)
paracetamol  (EXP,ISO)
PCB138  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (ISO)
pirinixic acid  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
pyrimidifen  (ISO)
resveratrol  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (ISO)
sunitinib  (ISO)
tamoxifen  (ISO)
tebufenpyrad  (ISO)
testosterone  (EXP,ISO)
tetrachloromethane  (ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
topotecan  (EXP)
Tributyltin oxide  (ISO)
trichloroethene  (EXP,ISO)
trimellitic anhydride  (ISO)
triphenyl phosphate  (ISO)
triptonide  (ISO)
tunicamycin  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Structure-function evolution of the transforming acidic coiled coil genes revealed by analysis of phylogenetically diverse organisms. Still IH, etal., BMC Evol Biol 2004 Jun 18;4(1):16.
Additional References at PubMed
PMID:11025203   PMID:11847113   PMID:12237944   PMID:17920017   PMID:21297582   PMID:23532825  


Genomics

Comparative Map Data
Tacc3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81481,275,755 - 81,289,894 (-)NCBIGRCr8
GRCr8 Ensembl1481,275,755 - 81,289,698 (-)EnsemblGRCr8 Ensembl
mRatBN7.21477,051,209 - 77,065,343 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1477,051,215 - 77,065,219 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1481,503,501 - 81,517,450 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01482,744,101 - 82,758,050 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01479,189,401 - 79,203,350 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01482,336,283 - 82,350,069 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1482,336,324 - 82,347,679 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01483,025,668 - 83,039,454 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41482,746,460 - 82,760,864 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1475,974,760 - 75,988,702 (-)NCBICelera
RGSC_v3.11482,748,850 - 82,763,255 (-)NCBI
Cytogenetic Map14q21NCBI
TACC3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3841,721,521 - 1,745,171 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl41,712,858 - 1,745,171 (+)EnsemblGRCh38hg38GRCh38
GRCh3741,723,248 - 1,746,898 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3641,693,062 - 1,716,696 (+)NCBINCBI36Build 36hg18NCBI36
Build 3441,690,496 - 1,714,126NCBI
Celera41,634,312 - 1,657,939 (+)NCBICelera
Cytogenetic Map4p16.3NCBI
HuRef41,666,111 - 1,689,797 (+)NCBIHuRef
CHM1_141,721,189 - 1,744,883 (+)NCBICHM1_1
T2T-CHM13v2.041,719,323 - 1,742,998 (+)NCBIT2T-CHM13v2.0
Tacc3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39533,814,808 - 33,836,331 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl533,815,472 - 33,836,339 (+)EnsemblGRCm39 Ensembl
GRCm38533,658,128 - 33,672,203 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl533,658,128 - 33,678,995 (+)EnsemblGRCm38mm10GRCm38
MGSCv37534,000,796 - 34,014,847 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36533,975,519 - 33,989,055 (+)NCBIMGSCv36mm8
Celera531,134,263 - 31,148,314 (+)NCBICelera
Cytogenetic Map5B2NCBI
cM Map517.83NCBI
Tacc3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955514975,176 - 986,686 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955514973,457 - 986,640 (+)NCBIChiLan1.0ChiLan1.0
TACC3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v232,049,942 - 2,074,164 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan141,985,172 - 2,009,451 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v041,858,595 - 1,882,727 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.141,772,836 - 1,796,019 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl41,772,836 - 1,796,019 (+)Ensemblpanpan1.1panPan2
TACC3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1362,368,641 - 62,380,898 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl362,368,642 - 62,381,024 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha364,886,359 - 64,898,622 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0362,844,062 - 62,856,319 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl362,844,062 - 62,856,561 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1362,337,573 - 62,349,822 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0362,541,079 - 62,553,340 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0362,900,317 - 62,912,580 (-)NCBIUU_Cfam_GSD_1.0
Tacc3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440528567,947,880 - 67,964,536 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647721,648,716 - 21,665,625 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647721,648,958 - 21,665,855 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TACC3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl8824,999 - 837,322 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.18825,433 - 835,425 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.28296,955 - 306,651 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TACC3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12747,021,970 - 47,045,571 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2747,021,965 - 47,045,223 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660513,398,606 - 3,422,223 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tacc3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475525,683,137 - 25,692,504 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475525,683,314 - 25,695,102 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Tacc3
79 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:123
Count of miRNA genes:99
Interacting mature miRNAs:107
Transcripts:ENSRNOT00000032972
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2313089Bss81Bone structure and strength QTL 813.40.0001body length (VT:0001256)body length, nose to rump (CMO:0000079)143802371083023710Rat
9590294Uminl4Urine mineral level QTL 45.660.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)1459848686104848686Rat
1582236Gluco22Glucose level QTL 223.30.0164blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)147764007196755654Rat
2300197Scl59Serum cholesterol level QTL 59blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)1477914838104348525Rat
70214Niddm28Non-insulin dependent diabetes mellitus QTL 284.06blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)143900944484009444Rat
70153Bp59Blood pressure QTL 593.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)147297021087582095Rat
70187Pancm5Pancreatic morphology QTL 516.7pancreas mass (VT:0010144)pancreas weight to body weight ratio (CMO:0000630)143067446985041098Rat
631523Pia13Pristane induced arthritis QTL 133.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1433424686102238540Rat
1582259Gluco23Glucose level QTL 233.10.0008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1474255551109089856Rat
1582197Gluco27Glucose level QTL 273.40.0006blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)147764007196755654Rat
2313100Bss82Bone structure and strength QTL 8230.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)143802371083023710Rat
634328Hc5Hypercalciuria QTL 52.3urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1462398852107398852Rat
1582250Gluco26Glucose level QTL 263.30.0009blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1477640071100078267Rat
2317879Alcrsp27Alcohol response QTL 273.30.63response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)1460854936105854936Rat
1641900Alcrsp11Alcohol response QTL 11alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)1474255551109089856Rat
631839Niddm37Non-insulin dependent diabetes mellitus QTL 373.37blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1411334716100078267Rat
1582255Gluco29Glucose level QTL 293.10.0025blood glucose amount (VT:0000188)absolute change in blood glucose level area under curve (CMO:0002034)147764007196755654Rat
9589034Epfw11Epididymal fat weight QTL 1160.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)1459848686104848686Rat
1582209Gluco20Glucose level QTL 203.80.0005blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)147764007196755654Rat
2313048Bss84Bone structure and strength QTL 843.10.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)143802371083023710Rat
1300136Rf22Renal function QTL 223.9renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)144261625899224555Rat
1549834Scl45Serum cholesterol level QTL 455.8blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)146592028399224555Rat
738037Hcas6Hepatocarcinoma susceptibility QTL 62.93liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)143941117087582095Rat
2313084Bss83Bone structure and strength QTL 832.90.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)143802371083023710Rat

Markers in Region
D12S364  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21477,051,575 - 77,052,012 (+)MAPPERmRatBN7.2
Rnor_6.01482,336,650 - 82,337,086NCBIRnor6.0
Rnor_5.01483,026,035 - 83,026,471UniSTSRnor5.0
RGSC_v3.41482,746,827 - 82,747,263UniSTSRGSC3.4
Celera1475,975,127 - 75,975,563UniSTS
Cytogenetic Map14q21UniSTS
RH142009  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81481,275,938 - 81,276,416 (+)Marker Load Pipeline
mRatBN7.21477,051,392 - 77,051,870 (+)MAPPERmRatBN7.2
Rnor_6.01482,336,467 - 82,336,944NCBIRnor6.0
Rnor_5.01483,025,852 - 83,026,329UniSTSRnor5.0
RGSC_v3.41482,746,644 - 82,747,121UniSTSRGSC3.4
Celera1475,974,944 - 75,975,421UniSTS
Cytogenetic Map14q21UniSTS
BE106930  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21477,053,163 - 77,053,323 (+)MAPPERmRatBN7.2
Rnor_6.01482,338,238 - 82,338,397NCBIRnor6.0
Rnor_5.01483,027,623 - 83,027,782UniSTSRnor5.0
RGSC_v3.41482,748,415 - 82,748,574UniSTSRGSC3.4
Celera1475,976,715 - 75,976,874UniSTS
RH 3.4 Map14501.57UniSTS
Cytogenetic Map14q21UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
9 11 49 113 91 90 59 25 59 6 218 97 11 93 45 60 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000032972   ⟹   ENSRNOP00000034933
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1481,275,755 - 81,288,752 (-)Ensembl
mRatBN7.2 Ensembl1477,051,215 - 77,064,290 (-)Ensembl
Rnor_6.0 Ensembl1482,336,324 - 82,347,679 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000095633   ⟹   ENSRNOP00000077218
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1481,275,755 - 81,289,698 (-)Ensembl
mRatBN7.2 Ensembl1477,051,215 - 77,065,219 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000097797   ⟹   ENSRNOP00000076588
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1481,275,755 - 81,289,698 (-)Ensembl
mRatBN7.2 Ensembl1477,051,215 - 77,065,219 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000103703   ⟹   ENSRNOP00000097835
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1481,275,755 - 81,289,698 (-)Ensembl
mRatBN7.2 Ensembl1477,051,215 - 77,065,219 (-)Ensembl
RefSeq Acc Id: NM_001004424   ⟹   NP_001004424
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81481,275,755 - 81,289,698 (-)NCBI
mRatBN7.21477,051,209 - 77,065,153 (-)NCBI
Rnor_6.01482,336,283 - 82,350,045 (-)NCBI
Rnor_5.01483,025,668 - 83,039,454 (-)NCBI
RGSC_v3.41482,746,460 - 82,760,864 (-)RGD
Celera1475,974,760 - 75,988,702 (-)RGD
Sequence:
RefSeq Acc Id: XM_006251329   ⟹   XP_006251391
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81481,275,755 - 81,289,819 (-)NCBI
mRatBN7.21477,051,209 - 77,065,265 (-)NCBI
Rnor_6.01482,336,283 - 82,350,065 (-)NCBI
Rnor_5.01483,025,668 - 83,039,454 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006251330   ⟹   XP_006251392
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81481,276,414 - 81,289,894 (-)NCBI
mRatBN7.21477,051,928 - 77,065,343 (-)NCBI
Rnor_6.01482,337,002 - 82,350,069 (-)NCBI
Rnor_5.01483,025,668 - 83,039,454 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039092209   ⟹   XP_038948137
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81481,279,438 - 81,289,894 (-)NCBI
mRatBN7.21477,054,892 - 77,065,343 (-)NCBI
RefSeq Acc Id: XM_063273388   ⟹   XP_063129458
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81481,276,414 - 81,289,844 (-)NCBI
RefSeq Acc Id: NP_001004424   ⟸   NM_001004424
- UniProtKB: A0A8I6ATD8 (UniProtKB/TrEMBL),   A0A8I5ZK91 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006251391   ⟸   XM_006251329
- Peptide Label: isoform X1
- UniProtKB: A0A8I5Y652 (UniProtKB/TrEMBL),   A0A8I5ZK91 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006251392   ⟸   XM_006251330
- Peptide Label: isoform X2
- UniProtKB: D3Z962 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000034933   ⟸   ENSRNOT00000032972
RefSeq Acc Id: XP_038948137   ⟸   XM_039092209
- Peptide Label: isoform X4
Ensembl Acc Id: ENSRNOP00000097835   ⟸   ENSRNOT00000103703
Ensembl Acc Id: ENSRNOP00000076588   ⟸   ENSRNOT00000097797
Ensembl Acc Id: ENSRNOP00000077218   ⟸   ENSRNOT00000095633
RefSeq Acc Id: XP_063129458   ⟸   XM_063273388
- Peptide Label: isoform X3
- UniProtKB: A0A8I5ZK91 (UniProtKB/TrEMBL)
Protein Domains
Transforming acidic coiled-coil-containing protein

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3Z962-F1-model_v2 AlphaFold D3Z962 1-587 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1302948 AgrOrtholog
BioCyc Gene G2FUF-15264 BioCyc
Ensembl Genes ENSRNOG00000017259 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000032972.5 UniProtKB/TrEMBL
  ENSRNOT00000095633.1 UniProtKB/TrEMBL
  ENSRNOT00000097797 ENTREZGENE
  ENSRNOT00000097797.1 UniProtKB/TrEMBL
  ENSRNOT00000103703 ENTREZGENE
  ENSRNOT00000103703.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.5.1700 UniProtKB/TrEMBL
InterPro Alp7/TACC UniProtKB/TrEMBL
  TACC UniProtKB/TrEMBL
NCBI Gene 360962 ENTREZGENE
PANTHER PTHR13924 UniProtKB/TrEMBL
  TRANSFORMING ACIDIC COILED-COIL-CONTAINING PROTEIN 3 UniProtKB/TrEMBL
Pfam TACC UniProtKB/TrEMBL
PhenoGen Tacc3 PhenoGen
RatGTEx ENSRNOG00000017259 RatGTEx
Superfamily-SCOP Tropomyosin UniProtKB/TrEMBL
UniProt A0A8I5Y652 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZK91 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6ATD8 ENTREZGENE, UniProtKB/TrEMBL
  A6IK54_RAT UniProtKB/TrEMBL
  A6IK55_RAT UniProtKB/TrEMBL
  D3Z962 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2006-03-30 Tacc3  transforming, acidic coiled-coil containing protein 3    transforming acidic coiled coil 3  Name updated 1299863 APPROVED
2005-02-14 Tacc3  transforming acidic coiled coil 3      Symbol and Name status set to provisional 70820 PROVISIONAL