Il15<sup>em1Soar</sup> (interleukin 15; ZFN induced mutant 1, Soar) - Rat Genome Database

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Gene: Il15em1Soar (interleukin 15; ZFN induced mutant 1, Soar) Rattus norvegicus
Symbol: Il15em1Soar
Name: interleukin 15; ZFN induced mutant 1, Soar
RGD ID: 12910491
Description: Zinc finger nuclease mediated 7bp deletion within exon 2 of the rat Il15 gene, resulting in a frameshift and premature stop codon.
ASSOCIATED WITH abnormal placenta junctional zone morphology; abnormal uterine spiral artery morphology; decreased NK cell number
Type: allele  of Il15  
Previously known as: Il15^[em1Soar]; Il15em1Soar
Is Marker For: Strains:   SD-Il15em1Soar  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position: No map positions available.

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype

References - curated
# Reference Title Reference Citation
1. A Critical Role for the Type I Interferon Receptor in Virus-Induced Autoimmune Diabetes in Rats. Qaisar N, etal., Diabetes. 2017 Jan;66(1):145-157. doi: 10.2337/db16-0462. Epub 2016 Oct 7.
2. Natural killer-cell deficiency alters placental development in rats. Renaud SJ, etal., Biol Reprod. 2017 Jan 1;96(1):145-158. doi: 10.1095/biolreprod.116.142752.


Allelic Variants
Name Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Assembly
Il15em1Soar-var1 chr19 25696013 25696019 CTTAACT - deletion mRatBN7.2
Il15em1Soar-var1 chr19 23553406 23553412 CTTAACT - deletion Rnor_6.0

Related Rat Strains
The following Strains have been annotated to Il15em1Soar



Nucleotide Sequences

Additional Information