Kcna1<sup>Adms</sup> (potassium voltage-gated channel subfamily A member 1;autosomal dominant myokymia and seizures) - Rat Genome Database

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Gene: Kcna1Adms (potassium voltage-gated channel subfamily A member 1;autosomal dominant myokymia and seizures) Rattus norvegicus
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Symbol: Kcna1Adms
Name: potassium voltage-gated channel subfamily A member 1;autosomal dominant myokymia and seizures
RGD ID: 12880383
Description: This allele was generated by phenotype-driven ENU mutagenesis. A Kcna1 S309T mutation was identified in rat Kcna1 gene.
ASSOCIATED WITH convulsive seizures; environmentally induced seizures; ASSOCIATED WITH epilepsy with generalized tonic-clonic seizures; episodic ataxia type 1; Myokymia
Type: allele  of Kcna1  
Previously known as: Kcna1^[Adms]; Kcna1Adms
Is Marker For: Strains:   F344-Kcna1Adms/Kyo  
Latest Assembly: GRCr8 - GRCr8 Assembly
Position: No map positions available.


Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Kcna1-mutant rats dominantly display myokymia, neuromyotonia and spontaneous epileptic seizures. Ishida S, etal., Brain Res. 2012 Jan 30;1435:154-66. doi: 10.1016/j.brainres.2011.11.023. Epub 2011 Nov 13.

Genomics


Related Rat Strains
The following Strains have been annotated to Kcna1Adms
F344-Kcna1Adms/Kyo    


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences


Additional Information