Dmd<sup>em1Ang</sup> (dystrophin; TALEN-induced mutant1, Ang) - Rat Genome Database

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Gene: Dmdem1Ang (dystrophin; TALEN-induced mutant1, Ang) Rattus norvegicus
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Symbol: Dmdem1Ang
Name: dystrophin; TALEN-induced mutant1, Ang
RGD ID: 12880032
Description: This mutant allele was generated using TALEN targeting exon23 of rat Dmd. The resulting mutant is a 11 bp-deletion in exon 23 leading to a +1 frame shift and premature stop codon 81 bp after the mutation.
ASSOCIATED WITH abnormal heart echocardiography feature; decreased body length; decreased body mass index; ASSOCIATED WITH Cardiac Fibrosis; dilated cardiomyopathy; Duchenne muscular dystrophy
Type: allele  of Dmd  
Previously known as: Dmdmdx; Dmd^[em1Ang]; Dmdem1Ang
Is Marker For: Strains:   SD-Dmdem1Ang  
Latest Assembly: GRCr8 - GRCr8 Assembly
Position: No map positions available.


References

References - curated
# Reference Title Reference Citation
1. Characterization of dystrophin deficient rats: a new model for Duchenne muscular dystrophy. Larcher T, etal., PLoS One. 2014 Oct 13;9(10):e110371. doi: 10.1371/journal.pone.0110371. eCollection 2014.

Genomics

Allelic Variants
Name Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Assembly
Dmdem1Ang-var1 chrX 48090661 48090671 CAACAAAATGG - deletion mRatBN7.2
Dmdem1Ang-var1 chrX 52104979 52104989 CAACAAAATGG - deletion Rnor_6.0

Related Rat Strains
The following Strains have been annotated to Dmdem1Ang
SD-Dmdem1Ang    


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences


Additional Information