Il2rg<sup>em1Kyo</sup> (interleukin 2 receptor subunit gamma; ZFN induced mutant 1, Kyo)

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Gene: Il2rg^em1Kyo (interleukin 2 receptor subunit gamma; ZFN induced mutant 1, Kyo) Rattus norvegicus

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Symbol:	Il2rg^em1Kyo
Name:	interleukin 2 receptor subunit gamma; ZFN induced mutant 1, Kyo
RGD ID:	12798560
Description:	These ZFN mutant rats were produced by injecting zinc finger nuclease targeting rat Il2rg into F344/Stm and TM/Kyo embryos.A 660-bp deletion mutation was created and resulted no detectable protein expression by western blot. ASSOCIATED WITH combined T cell and B cell immunodeficiency; X-linked severe combined immunodeficiency
Type:	allele of Il2rg
Previously known as:	Il2rgem1Kyo
Is Marker For:	Strains: F344-Il2rg^em1Kyo
Latest Assembly:	mRatBN7.2 - mRatBN7.2 Assembly
Position:	No map positions available.

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Disease Annotations Click to see Annotation Detail View

combined T cell and B cell immunodeficiency (IMP)

X-linked severe combined immunodeficiency (IMP)

References

References - curated

#	Reference Title	Reference Citation
1.	Generation of knockout rats with X-linked severe combined immunodeficiency (X-SCID) using zinc-finger nucleases.	Mashimo T, etal., PLoS One. 2010 Jan 25;5(1):e8870.

Genomics

Related Rat Strains

The following Strains have been annotated to Il2rg^em1Kyo

F344-Il2rg^em1Kyo

Expression

Sequence

Nucleotide Sequences

Additional Information

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InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
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MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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