Il2rg<sup>em1Kyo</sup> (interleukin 2 receptor subunit gamma; ZFN induced mutant 1, Kyo) - Rat Genome Database

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Gene: Il2rgem1Kyo (interleukin 2 receptor subunit gamma; ZFN induced mutant 1, Kyo) Rattus norvegicus
Symbol: Il2rgem1Kyo
Name: interleukin 2 receptor subunit gamma; ZFN induced mutant 1, Kyo
RGD ID: 12798560
Description: These ZFN mutant rats were produced by injecting zinc finger nuclease targeting rat Il2rg into F344/Stm and TM/Kyo embryos.A 660-bp deletion mutation was created and resulted no detectable protein expression by western blot.
ASSOCIATED WITH combined T cell and B cell immunodeficiency; X-linked severe combined immunodeficiency
Type: allele  of Il2rg  
Previously known as: Il2rgem1Kyo
Is Marker For: Strains:   F344-Il2rgem1Kyo  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position: No map positions available.

Disease Annotations     Click to see Annotation Detail View


References - curated
# Reference Title Reference Citation
1. Generation of knockout rats with X-linked severe combined immunodeficiency (X-SCID) using zinc-finger nucleases. Mashimo T, etal., PLoS One. 2010 Jan 25;5(1):e8870.


Related Rat Strains
The following Strains have been annotated to Il2rgem1Kyo



Nucleotide Sequences

Additional Information