Dpp4<sup>DPPIV</sup> (dipeptidylpeptidase 4; DPPIV mutant) - Rat Genome Database

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Gene: Dpp4DPPIV (dipeptidylpeptidase 4; DPPIV mutant) Rattus norvegicus
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Symbol: Dpp4DPPIV
Name: dipeptidylpeptidase 4; DPPIV mutant
RGD ID: 12792942
Description: The DPP4 mutant allele was a spontaneous mutation found in Fischer 344 rats, which caused a deficiency in Dpp4. The mutant allele has a G to A change at nucleotide 1897 (in exon 22), which results in an amino acid change of Gly (WT; GGA) to Arg (Mut; AGA).
ASSOCIATED WITH decreased anxiety-related response; decreased circulating adrenocorticotropin level; decreased circulating alanine transaminase level
Type: allele  of Dpp4  
Previously known as: Dpp4DPPIV-; Dpp4DPPIV-
Is Marker For: Strains:   F344-Dpp4DPPIV-/DchcHsdRrrc   DA.F344-Dpp4DPPIV/SvH  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position: No map positions available.


References

References - curated
# Reference Title Reference Citation
1. Phenotyping of congenic dipeptidyl peptidase 4 (DP4) deficient Dark Agouti (DA) rats suggests involvement of DP4 in neuro-, endocrine, and immune functions. Frerker N, etal., Clin Chem Lab Med. 2009;47(3):275-87. doi: 10.1515/CCLM.2009.064.

Genomics


Related Rat Strains
The following Strains have been annotated to Dpp4DPPIV


Expression


Sequence

Nucleotide Sequences


Additional Information


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-02-09 Dpp4DPPIV  dipeptidylpeptidase 4; DPPIV mutant  Dpp4DPPIV-  dipeptidylpeptidase 4; DPPIV mutant  Symbol changed 629549 APPROVED