Abcc2<sup>TR-</sup> (ATP binding cassette subfamily C member 2;transport deficient mutant ,) - Rat Genome Database

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Gene: Abcc2TR- (ATP binding cassette subfamily C member 2;transport deficient mutant ,) Rattus norvegicus
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Symbol: Abcc2TR-
Name: ATP binding cassette subfamily C member 2;transport deficient mutant ,
RGD ID: 12792941
Description: Spontaneous mutation occurred on a Wistar Unilever maintained at the Amsterdam Academic Medical Center (AMC). It is a nonsense mutation caused by one bp deletion in the coding region of Abcc2.
ASSOCIATED WITH increased circulating bilirubin level
Type: allele  of Abcc2  
Previously known as: Abcc2^[TR-]; Abcc2TR-
Is Marker For: Strains:   WUN-Abcc2TR-/HsdRrrc  
Latest Assembly: GRCr8 - GRCr8 Assembly
Position: No map positions available.


Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Adenosine triphosphate-binding cassette subfamily C member 2 is the major transporter of the hepatobiliary imaging agent (99m)Tc-mebrofenin. Bhargava KK, etal., J Nucl Med. 2009 Jul;50(7):1140-6. doi: 10.2967/jnumed.109.062448. Epub 2009 Jun 12.
2. Congenital jaundice in rats with a mutation in a multidrug resistance-associated protein gene. Paulusma CC, etal., Science 1996 Feb 23;271(5252):1126-8.

Genomics


Related Rat Strains
The following Strains have been annotated to Abcc2TR-
WUN-Abcc2TR-/HsdRrrc    


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences


Additional Information