Pax6<sup>Sey2</sup> (paired box gene 6, small eye mutation 2) - Rat Genome Database

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Gene: Pax6Sey2 (paired box gene 6, small eye mutation 2) Rattus norvegicus
Symbol: Pax6Sey2
Name: paired box gene 6, small eye mutation 2
RGD ID: 12790970
Description: Genomic DNA analysis from mutants revealed a single base(c) insertion, resulting in a abnormal stop codon at 33-bp downstream from the insertion site due to frameshift.
ASSOCIATED WITH abnormal abducens nerve morphology; abnormal behavioral response to light; abnormal hypoglossal nerve morphology
Type: allele  of Pax6  
Previously known as: Pax6^[Sey2]; Pax6Sey2; rsey2
Is Marker For: Strains:   SD-Pax6Sey2/Mce  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position: No map positions available.


References - curated
# Reference Title Reference Citation
1. Study of Pax6 mutant rat revealed the association between upper incisor formation and midface formation. Kriangkrai R, etal., Dev Dyn. 2006 Aug;235(8):2134-43.
2. Pax-6 is involved in the specification of hindbrain motor neuron subtype. Osumi N, etal., Development 1997 Aug;124(15):2961-72.
3. Evaluation of Pax6 mutant rat as a model for autism. Umeda T, etal., PLoS One. 2010 Dec 21;5(12):e15500. doi: 10.1371/journal.pone.0015500.


Related Rat Strains
The following Strains have been annotated to Pax6Sey2



Nucleotide Sequences

Additional Information

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-02-23 Pax6Sey2  paired box gene 6, small eye mutation 2  Pax6Sey2  paired box gene 6, small eye mutation 2  Symbol changed 629549 APPROVED