Cfb<sup>em1Tja</sup> (complement factor B, ZFN induced mutant 1, Tja) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Cfbem1Tja (complement factor B, ZFN induced mutant 1, Tja) Rattus norvegicus
Analyze
Symbol: Cfbem1Tja
Name: complement factor B, ZFN induced mutant 1, Tja
RGD ID: 127285405
Description: This allele was produced by injecting ZFNs targeting exon 6 of rat complement factor b (Cfb) (target sequence: CCCCTCGGGCTCCATGaatatcTACATGGTGCTGGATG),into SHR/NCrl rat embryos. The resulting mutation is a 19-bp deletion.
ASSOCIATED WITH decreased brown adipose tissue amount; decreased circulating aldosterone level; decreased circulating cholesterol level
Type: allele  of Cfb  
Previously known as: Cfb^[em1Tja]
Is Marker For: Strains:   SHR-Cfbem1Tja  
Latest Assembly: GRCr8 - GRCr8 Assembly
Position: No map positions available.


References

References - curated
# Reference Title Reference Citation
1. Complement Factor B Is a Determinant of Both Metabolic and Cardiovascular Features of Metabolic Syndrome. Coan PM, etal., Hypertension. 2017 Jul 24. pii: HYPERTENSIONAHA.117.09242. doi: 10.1161/HYPERTENSIONAHA.117.09242.

Genomics


Related Rat Strains
The following Strains have been annotated to Cfbem1Tja


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences


Additional Information