Cfb<sup>em1Tja</sup> (complement factor B, ZFN induced mutant 1, Tja) - Rat Genome Database

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Gene: Cfbem1Tja (complement factor B, ZFN induced mutant 1, Tja) Rattus norvegicus
Symbol: Cfbem1Tja
Name: complement factor B, ZFN induced mutant 1, Tja
RGD ID: 127285405
Description: This allele was produced by injecting ZFNs targeting exon 6 of rat complement factor b (Cfb) (target sequence: CCCCTCGGGCTCCATGaatatcTACATGGTGCTGGATG),into SHR/NCrl rat embryos. The resulting mutation is a 19-bp deletion.
ASSOCIATED WITH decreased brown adipose tissue amount; decreased circulating aldosterone level; decreased circulating cholesterol level
Type: allele  of Cfb  
Previously known as: Cfb^[em1Tja]
Is Marker For: Strains:   SHR-Cfbem1Tja  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position: No map positions available.


References - curated
# Reference Title Reference Citation
1. Complement Factor B Is a Determinant of Both Metabolic and Cardiovascular Features of Metabolic Syndrome. Coan PM, etal., Hypertension. 2017 Jul 24. pii: HYPERTENSIONAHA.117.09242. doi: 10.1161/HYPERTENSIONAHA.117.09242.


Related Rat Strains
The following Strains have been annotated to Cfbem1Tja



Nucleotide Sequences

Additional Information