Aqp4<sup>em1Hrt</sup> (aquaporin 4; TALEN induced mutant 1, Hrt) - Rat Genome Database

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Gene: Aqp4em1Hrt (aquaporin 4; TALEN induced mutant 1, Hrt) Rattus norvegicus
Symbol: Aqp4em1Hrt
Name: aquaporin 4; TALEN induced mutant 1, Hrt
RGD ID: 127284884
Description: The transcription activator-like effector nuclease (TALEN)-mediated knockout approach was applied to generate this Aqp4 deletion allele. TALENs against the following sequences: (5′-CACAGCAGAGTTCCTGG-3′) for the sense strand and (5′-GGATCCCACGCTGAGCA-3′) for the antisense strand. This allele was identified with 3-bp deletion.
ASSOCIATED WITH abnormal glymphatic system physiology; ASSOCIATED WITH Subarachnoid Hemorrhage
Type: allele  of Aqp4  
Previously known as: Aqp4^[em1Hrt]
Is Marker For: Strains:   SD-Aqp4em1Hrt  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position: No map positions available.

Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype

References - curated
# Reference Title Reference Citation
1. The Involvement of Aquaporin-4 in the Interstitial Fluid Drainage Impairment Following Subarachnoid Hemorrhage. Liu E, etal., Front Aging Neurosci. 2021 Jan 26;12:611494. doi: 10.3389/fnagi.2020.611494. eCollection 2020.


Related Rat Strains
The following Strains have been annotated to Aqp4em1Hrt



Nucleotide Sequences

Additional Information