Edar (ectodysplasin A receptor) - Rat Genome Database

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Gene: Edar (ectodysplasin A receptor) Ictidomys tridecemlineatus
Analyze
Symbol: Edar
Name: ectodysplasin A receptor
RGD ID: 12691688
Description: ENCODES a protein that exhibits signaling receptor activity (inferred); transmembrane signaling receptor activity (inferred); INVOLVED IN apoptotic process (inferred); cell differentiation (inferred); cytokine-mediated signaling pathway (inferred); ASSOCIATED WITH Alpers-Huttenlocher syndrome (ortholog); anodontia (ortholog); autosomal dominant distal hereditary motor neuronopathy 7 (ortholog); FOUND IN apical part of cell (inferred); membrane (inferred); plasma membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: tumor necrosis factor receptor superfamily member EDAR
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629291,938,934 - 91,970,049 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936829429,561 - 458,943 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936829429,667 - 458,943 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse:




References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Edar
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629291,938,934 - 91,970,049 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936829429,561 - 458,943 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936829429,667 - 458,943 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EDAR
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382108,894,471 - 108,989,220 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2108,894,471 - 108,989,372 (-)Ensemblhg38GRCh38
GRCh372109,510,927 - 109,605,676 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362108,877,361 - 108,972,260 (-)NCBIBuild 36Build 36hg18NCBI36
Build 342108,969,448 - 109,064,346NCBI
Celera2103,820,860 - 103,915,790 (-)NCBICelera
Cytogenetic Map2q13NCBI
HuRef2103,109,351 - 103,204,259 (-)NCBIHuRef
CHM1_12109,515,194 - 109,610,098 (-)NCBICHM1_1
T2T-CHM13v2.02109,355,029 - 109,449,802 (-)NCBIT2T-CHM13v2.0
Edar
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391058,436,602 - 58,511,518 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1058,436,611 - 58,511,476 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381058,600,780 - 58,675,696 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1058,600,789 - 58,675,654 (-)Ensemblmm10GRCm38
MGSCv371058,063,536 - 58,138,444 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361058,582,058 - 58,656,978 (-)NCBIMGSCv36mm8
MGSCv361057,996,146 - 58,071,053 (-)NCBIMGSCv36mm8
Cytogenetic Map10B4NCBI
cM Map1029.37NCBI
Edar
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82027,130,934 - 27,209,672 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl2027,130,934 - 27,209,630 (-)EnsemblGRCr8
mRatBN7.22026,587,836 - 26,666,543 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2026,587,839 - 26,666,494 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx2027,595,453 - 27,623,881 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02026,981,678 - 27,010,102 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02027,726,632 - 27,755,014 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.02028,179,132 - 28,263,092 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2028,179,140 - 28,263,037 (-)Ensemblrn6Rnor6.0
Rnor_5.02029,996,972 - 30,079,875 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.42037,135,534 - 37,164,197 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera2028,038,358 - 28,066,702 (-)NCBICelera
Cytogenetic Map20q11NCBI
Edar
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495547012,309,048 - 12,362,570 (-)Ensembl
ChiLan1.0NW_00495547012,310,680 - 12,362,555 (-)NCBIChiLan1.0ChiLan1.0
EDAR
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21221,025,847 - 21,060,049 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A21,008,536 - 21,062,814 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A95,132,396 - 95,172,218 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A110,146,499 - 110,241,556 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A110,146,499 - 110,234,398 (-)EnsemblpanPan2panpan1.1
EDAR
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11034,873,311 - 34,943,140 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1034,848,526 - 34,940,784 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1034,772,071 - 34,866,543 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01035,700,824 - 35,795,378 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1035,700,812 - 35,795,448 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11035,430,446 - 35,524,880 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01035,712,643 - 35,807,092 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01035,901,219 - 35,995,761 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
EDAR
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl347,396,330 - 47,465,784 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1347,396,303 - 47,466,234 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2349,558,908 - 49,626,194 (+)NCBISscrofa10.2Sscrofa10.2susScr3
EDAR
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11412,430,405 - 12,527,160 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1412,433,418 - 12,468,841 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660807,173,441 - 7,274,919 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Edar
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474911,983,550 - 11,998,918 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462474911,981,782 - 11,998,933 (-)NCBIHetGla 1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSSTOT00000021076   ⟹   ENSSTOP00000017802
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_004936829429,561 - 458,943 (-)Ensembl
RefSeq Acc Id: XM_040270880   ⟹   XP_040126814
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440629291,938,934 - 91,970,049 (+)NCBI
Protein Sequences
Protein RefSeqs XP_040126814 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000017802.1
GenBank Protein KAG3268168 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_040126814   ⟸   XM_040270880
- UniProtKB: I3N0A6 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSSTOP00000017802   ⟸   ENSSTOT00000021076
Protein Domains
Tumor necrosis factor receptor superfamily member


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000023189 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000021076.2 UniProtKB/TrEMBL
Gene3D-CATH 1.10.533.10 UniProtKB/TrEMBL
  Tumor Necrosis Factor Receptor, subunit A, domain 2 UniProtKB/TrEMBL
InterPro DEATH-like_dom_sf UniProtKB/TrEMBL
  Death_EDAR UniProtKB/TrEMBL
  EDAR_N UniProtKB/TrEMBL
  TNR19/27/EDAR UniProtKB/TrEMBL
NCBI Gene Edar ENTREZGENE
PANTHER TNFR-CYS DOMAIN-CONTAINING PROTEIN UniProtKB/TrEMBL
  TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER EDAR UniProtKB/TrEMBL
Pfam Death_EDAR UniProtKB/TrEMBL
Superfamily-SCOP SSF47986 UniProtKB/TrEMBL
UniProt I3N0A6 ENTREZGENE, UniProtKB/TrEMBL