Lpar1<sup>m1Hubr</sup> (lysophosphatidic acid receptor 1; ENU induced mutant 1, Hubr) - Rat Genome Database

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Gene: Lpar1m1Hubr (lysophosphatidic acid receptor 1; ENU induced mutant 1, Hubr) Rattus norvegicus
Symbol: Lpar1m1Hubr
Name: lysophosphatidic acid receptor 1; ENU induced mutant 1, Hubr
RGD ID: 126848739
Description: This allele carried an ENU-induced missense mutation in Lpar1 that resulted in the change of a methionine into an arginine (p.M318R) in the 8th helix and that was predicted to be deleterious for protein function. This allele was identified from target-selected ENU-driven mutagenesis of male MSH6 knockout rats.
ASSOCIATED WITH abnormal craniofacial development; decreased body size
Type: allele  of Lpar1  
Is Marker For: Strains:   WI- Lpar1m1Hubr  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position: No map positions available.

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype

References - curated
# Reference Title Reference Citation
1. Systematic generation of in vivo G protein-coupled receptor mutants in the rat. van Boxtel R, etal., Pharmacogenomics J. 2011 Oct;11(5):326-36. doi: 10.1038/tpj.2010.44. Epub 2010 Jun 8.


Related Rat Strains
The following Strains have been annotated to Lpar1m1Hubr



Nucleotide Sequences

Additional Information