Mkx<sup>em1Asah</sup> (mohawk homeobox; CRISPR/Cas9 system induced mutant 1, Asah) - Rat Genome Database

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Gene: Mkxem1Asah (mohawk homeobox; CRISPR/Cas9 system induced mutant 1, Asah) Rattus norvegicus
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Symbol: Mkxem1Asah
Name: mohawk homeobox; CRISPR/Cas9 system induced mutant 1, Asah
RGD ID: 126777685
Description: The CRISPR/Cas9 genome editing system targeting exon 2 of rat Mkx gene was injected to the Wistar embryo to generate this knock out allele with 14- bp deletion causing frameshift mutation in the gene.
ASSOCIATED WITH abnormal gait; abnormal tendon collagen fibril morphology; abnormal tendon morphology; ASSOCIATED WITH Heterotopic Ossification
Type: allele  of Mkx  
Previously known as: Mkx^[em1Asah]
Is Marker For: Strains:   WI-Mkxem1Asah  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position: No map positions available.


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Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Gene targeting of the transcription factor Mohawk in rats causes heterotopic ossification of Achilles tendon via failed tenogenesis. Suzuki H, etal., Proc Natl Acad Sci U S A. 2016 Jul 12;113(28):7840-5. doi: 10.1073/pnas.1522054113. Epub 2016 Jul 1.

Genomics


Related Rat Strains
The following Strains have been annotated to Mkxem1Asah


Expression


Sequence

Nucleotide Sequences


Additional Information