Nr4a1 (nuclear receptor subfamily 4 group A member 1) - Rat Genome Database

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Gene: Nr4a1 (nuclear receptor subfamily 4 group A member 1) Ictidomys tridecemlineatus
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Symbol: Nr4a1
Name: nuclear receptor subfamily 4 group A member 1
RGD ID: 12677219
Description: ENCODES a protein that exhibits protein heterodimerization activity (ortholog); INVOLVED IN apoptotic process (ortholog); neurotransmitter secretion involved in regulation of skeletal muscle contraction (ortholog); positive regulation of apoptotic process (ortholog); ASSOCIATED WITH Albuminuria (ortholog); blood pressure trait (ortholog); blood urea nitrogen amount (ortholog); FOUND IN chromatin (inferred); cytosol (inferred); mitochondrion (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: nuclear receptor subfamily 4 group A member 1, transcript variant X1; nuclear receptor subfamily 4 group A member 1, transcript variant X2; nuclear receptor subfamily 4 group A member 1, transcript variant X3; nuclear receptor subfamily 4 group A member 1, transcript variant X4; nuclear receptor subfamily 4 group A member 1, transcript variant X5; nuclear receptor subfamily 4 group A member 1, transcript variant X6
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494563,656,496 - 63,678,740 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365129,499,754 - 9,508,423 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365129,486,096 - 9,508,338 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model



Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component


References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Nr4a1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494563,656,496 - 63,678,740 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365129,499,754 - 9,508,423 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365129,486,096 - 9,508,338 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NR4A1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381252,022,832 - 52,059,503 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1252,022,832 - 52,059,507 (+)EnsemblGRCh38hg38GRCh38
GRCh371252,416,616 - 52,453,287 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361250,731,458 - 50,739,554 (+)NCBINCBI36Build 36hg18NCBI36
Build 341250,723,762 - 50,736,019NCBI
Celera1251,247,867 - 51,255,961 (+)NCBICelera
Cytogenetic Map12q13.13NCBI
HuRef1249,449,770 - 49,486,519 (+)NCBIHuRef
CHM1_11252,382,884 - 52,419,560 (+)NCBICHM1_1
T2T-CHM13v2.01251,986,402 - 52,023,082 (+)NCBIT2T-CHM13v2.0
Nr4a1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3915101,151,783 - 101,172,676 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl15101,152,150 - 101,172,676 (+)EnsemblGRCm39 Ensembl
GRCm3815101,253,902 - 101,274,795 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl15101,254,269 - 101,274,795 (+)EnsemblGRCm38mm10GRCm38
MGSCv3715101,097,277 - 101,105,226 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3615101,094,896 - 101,102,826 (+)NCBIMGSCv36mm8
Celera15103,414,983 - 103,422,853 (+)NCBICelera
Cytogenetic Map15F1NCBI
cM Map1556.64NCBI
Nr4a1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87134,247,153 - 134,268,044 (+)NCBIGRCr8
mRatBN7.27132,368,399 - 132,389,300 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7132,374,840 - 132,389,297 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7134,182,933 - 134,190,833 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07136,412,449 - 136,420,349 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07136,322,869 - 136,330,773 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07142,899,358 - 142,920,216 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7142,905,758 - 142,920,216 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07140,700,242 - 140,721,073 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47140,012,807 - 140,020,590 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17140,089,243 - 140,097,024 (+)NCBI
Celera7128,846,928 - 128,854,640 (+)NCBICelera
Cytogenetic Map7q36NCBI
Nr4a1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555472,404,532 - 2,431,050 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555472,404,532 - 2,426,882 (+)NCBIChiLan1.0ChiLan1.0
NR4A1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21042,136,340 - 42,158,166 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11242,133,103 - 42,154,924 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01236,703,903 - 36,740,211 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11237,480,300 - 37,498,290 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1237,480,300 - 37,501,188 (-)Ensemblpanpan1.1panPan2
NR4A1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1272,947,729 - 2,965,045 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl272,891,053 - 2,955,655 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2743,300,499 - 43,308,433 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0272,944,790 - 2,966,939 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl272,939,797 - 2,965,600 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1272,961,332 - 2,969,256 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0272,947,820 - 2,955,733 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02743,698,715 - 43,706,655 (+)NCBIUU_Cfam_GSD_1.0
NR4A1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11148,208,354 - 48,232,857 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1148,208,587 - 48,233,063 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037197,859,302 - 197,884,070 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nr4a1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624816267,303 - 293,227 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624816271,345 - 288,265 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSSTOT00000026154   ⟹   ENSSTOP00000015534
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365129,499,754 - 9,508,423 (+)Ensembl
RefSeq Acc Id: XM_005324980   ⟹   XP_005325037
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494563,656,496 - 63,665,001 (-)NCBI
SpeTri2.0NW_0049365129,499,796 - 9,508,338 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013358495   ⟹   XP_013213949
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494563,656,496 - 63,678,740 (-)NCBI
SpeTri2.0NW_0049365129,489,500 - 9,508,338 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021726180   ⟹   XP_021581855
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494563,656,496 - 63,678,740 (-)NCBI
SpeTri2.0NW_0049365129,486,096 - 9,508,338 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021726181   ⟹   XP_021581856
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494563,656,496 - 63,678,739 (-)NCBI
SpeTri2.0NW_0049365129,489,500 - 9,508,338 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021726182   ⟹   XP_021581857
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494563,656,496 - 63,678,740 (-)NCBI
SpeTri2.0NW_0049365129,489,500 - 9,508,338 (+)NCBI
Sequence:
RefSeq Acc Id: XM_040280616   ⟹   XP_040136550
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494563,656,496 - 63,678,740 (-)NCBI
RefSeq Acc Id: XM_040280617   ⟹   XP_040136551
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494563,656,496 - 63,678,740 (-)NCBI
RefSeq Acc Id: XP_013213949   ⟸   XM_013358495
- UniProtKB: I3MTT9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005325037   ⟸   XM_005324980
- UniProtKB: I3MTT9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_021581855   ⟸   XM_021726180
- UniProtKB: I3MTT9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_021581856   ⟸   XM_021726181
- UniProtKB: I3MTT9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_021581857   ⟸   XM_021726182
- UniProtKB: I3MTT9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_040136550   ⟸   XM_040280616
- UniProtKB: I3MTT9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040136551   ⟸   XM_040280617
- UniProtKB: I3MTT9 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSSTOP00000015534   ⟸   ENSSTOT00000026154
Protein Domains
NR LBD   Nuclear receptor


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000019650 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000026154.2 UniProtKB/TrEMBL
Gene3D-CATH 1.10.565.10 UniProtKB/TrEMBL
  3.30.50.10 UniProtKB/TrEMBL
InterPro NHR-like_dom_sf UniProtKB/TrEMBL
  Nuc_orp_HMR_rcpt UniProtKB/TrEMBL
  Nuc_orph_rcpt UniProtKB/TrEMBL
  Nucl_hrmn_rcpt_lig-bd UniProtKB/TrEMBL
  Nuclear_hrmn_rcpt UniProtKB/TrEMBL
  Znf_hrmn_rcpt UniProtKB/TrEMBL
  Znf_NHR/GATA UniProtKB/TrEMBL
NCBI Gene Nr4a1 ENTREZGENE
PANTHER NUCLEAR HORMONE RECEPTOR UniProtKB/TrEMBL
  NUCLEAR RECEPTOR SUBFAMILY 4 GROUP A MEMBER 1 UniProtKB/TrEMBL
Pfam Hormone_recep UniProtKB/TrEMBL
  zf-C4 UniProtKB/TrEMBL
PRINTS HMRNUCRECPTR UniProtKB/TrEMBL
  NUCLEARECPTR UniProtKB/TrEMBL
  STRDHORMONER UniProtKB/TrEMBL
  STROIDFINGER UniProtKB/TrEMBL
PROSITE NR_LBD UniProtKB/TrEMBL
  NUCLEAR_REC_DBD_1 UniProtKB/TrEMBL
  NUCLEAR_REC_DBD_2 UniProtKB/TrEMBL
SMART HOLI UniProtKB/TrEMBL
  ZnF_C4 UniProtKB/TrEMBL
Superfamily-SCOP Glucocorticoid receptor-like (DNA-binding domain) UniProtKB/TrEMBL
  SSF48508 UniProtKB/TrEMBL
UniProt I3MTT9 ENTREZGENE, UniProtKB/TrEMBL