Lims1 (LIM zinc finger domain containing 1) - Rat Genome Database

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Pathways
Gene: Lims1 (LIM zinc finger domain containing 1) Ictidomys tridecemlineatus
Analyze
Symbol: Lims1
Name: LIM zinc finger domain containing 1
RGD ID: 12653195
Description: ENCODES a protein that exhibits protein kinase binding (ortholog); protein-containing complex binding (ortholog); zinc ion binding (ortholog); INVOLVED IN cell-cell adhesion (ortholog); cell-cell junction organization (ortholog); cell-matrix adhesion (ortholog); PARTICIPATES IN integrin mediated signaling pathway; ASSOCIATED WITH autosomal dominant distal hereditary motor neuronopathy 7 (ortholog); ectodermal dysplasia 10A (ortholog); ectodermal dysplasia 10B (ortholog); FOUND IN perinuclear region of cytoplasm (ortholog); protein-containing complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LIM and senescent cell antigen-like-containing domain protein 1; LIM zinc finger domain containing 1, transcript variant X1; LIM zinc finger domain containing 1, transcript variant X2; LIM zinc finger domain containing 1, transcript variant X3; LIM zinc finger domain containing 1, transcript variant X4
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629292,157,129 - 92,210,709 (-)NCBIHiC_Itri_2
SpeTri2.0NW_004936829187,234 - 240,213 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Lims1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629292,157,129 - 92,210,709 (-)NCBIHiC_Itri_2
SpeTri2.0NW_004936829187,234 - 240,213 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LIMS1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382108,533,671 - 108,687,246 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2108,533,671 - 108,687,246 (+)Ensemblhg38GRCh38
GRCh372109,150,127 - 109,303,702 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362108,571,199 - 108,667,321 (+)NCBIBuild 36Build 36hg18NCBI36
Build 342108,663,284 - 108,759,405NCBI
Celera2103,464,751 - 103,615,238 (+)NCBICelera
Cytogenetic Map2q12.3NCBI
HuRef2102,803,913 - 102,903,724 (+)NCBIHuRef
CHM1_12109,154,977 - 109,307,968 (+)NCBICHM1_1
T2T-CHM13v2.02108,994,291 - 109,147,842 (+)NCBIT2T-CHM13v2.0
Lims1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391058,159,164 - 58,260,513 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1058,159,288 - 58,260,513 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381058,323,342 - 58,424,691 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1058,323,466 - 58,424,691 (+)Ensemblmm10GRCm38
MGSCv371057,786,295 - 57,887,437 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361057,718,904 - 57,820,046 (+)NCBIMGSCv36mm8
Celera1059,061,688 - 59,162,733 (+)NCBICelera
Cytogenetic Map10B4NCBI
cM Map1029.31NCBI
Lims1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82026,851,364 - 26,961,607 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl2026,852,996 - 26,961,606 (+)EnsemblGRCr8
mRatBN7.22026,309,833 - 26,418,511 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2026,309,895 - 26,418,500 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx2027,370,767 - 27,418,134 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02026,757,119 - 26,804,483 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02027,505,048 - 27,552,462 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.02027,895,981 - 28,004,767 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2027,954,433 - 28,002,082 (+)Ensemblrn6Rnor6.0
Rnor_5.02029,715,580 - 29,824,252 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.42037,349,188 - 37,397,427 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera2027,819,971 - 27,867,155 (+)NCBICelera
Cytogenetic Map20q11NCBI
Lims1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495547012,120,452 - 12,161,255 (+)Ensembl
ChiLan1.0NW_00495547012,142,997 - 12,158,273 (+)NCBIChiLan1.0ChiLan1.0
LIMS1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21220,662,566 - 20,817,774 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A20,665,357 - 20,820,538 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A94,739,338 - 94,928,835 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A109,847,189 - 109,890,827 (+)NCBIPanPan1.1PanPan1.1panPan2
LIMS1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11035,192,582 - 35,339,100 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1035,115,177 - 35,261,730 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01036,045,342 - 36,192,076 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1036,045,345 - 36,192,039 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11035,774,284 - 35,920,701 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01036,057,448 - 36,204,222 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01036,249,779 - 36,396,408 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
LIMS1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl347,606,230 - 47,672,884 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1347,607,737 - 47,704,921 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2349,748,396 - 49,812,059 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LIMS1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11412,059,347 - 12,210,779 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1412,059,411 - 12,213,064 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660807,500,757 - 7,651,520 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Lims1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474911,720,492 - 11,846,571 (+)NCBIHetGla 1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


RefSeq Acc Id: XM_005340933   ⟹   XP_005340990
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440629292,157,129 - 92,183,595 (-)NCBI
SpeTri2.0NW_004936829214,277 - 240,213 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005340934   ⟹   XP_005340991
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440629292,157,129 - 92,210,709 (-)NCBI
SpeTri2.0NW_004936829187,234 - 240,213 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013365506   ⟹   XP_013220960
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440629292,159,856 - 92,183,595 (-)NCBI
SpeTri2.0NW_004936829214,277 - 240,213 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021720614   ⟹   XP_021576289
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440629292,159,856 - 92,182,983 (-)NCBI
SpeTri2.0NW_004936829214,841 - 240,213 (+)NCBI
Sequence:
RefSeq Acc Id: XM_040270883   ⟹   XP_040126817
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440629292,157,129 - 92,183,595 (-)NCBI
RefSeq Acc Id: XM_040270884   ⟹   XP_040126818
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440629292,157,129 - 92,183,595 (-)NCBI
RefSeq Acc Id: XM_040270885   ⟹   XP_040126819
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440629292,159,856 - 92,210,709 (-)NCBI
RefSeq Acc Id: XP_005340991   ⟸   XM_005340934
- Peptide Label: isoform X6
- UniProtKB: I3MQ88 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005340990   ⟸   XM_005340933
- Peptide Label: isoform X4
- UniProtKB: I3MQ88 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013220960   ⟸   XM_013365506
- Peptide Label: isoform X1
- UniProtKB: I3NAG1 (UniProtKB/TrEMBL),   I3MQ88 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_021576289   ⟸   XM_021720614
- Peptide Label: isoform X7
- UniProtKB: I3MQ88 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_040126817   ⟸   XM_040270883
- Peptide Label: isoform X2
- UniProtKB: I3MQ88 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040126818   ⟸   XM_040270884
- Peptide Label: isoform X3
- UniProtKB: I3MQ88 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040126819   ⟸   XM_040270885
- Peptide Label: isoform X5
- UniProtKB: I3MQ88 (UniProtKB/TrEMBL)
Protein Domains
LIM zinc-binding


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000015716 UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000015721.3 UniProtKB/TrEMBL
  ENSSTOT00000028573.2 UniProtKB/TrEMBL
Gene3D-CATH Cysteine Rich Protein UniProtKB/TrEMBL
InterPro LIMS1/2-like_LIM1 UniProtKB/TrEMBL
  PINCH-1-4-like UniProtKB/TrEMBL
  PINCH-1/2-like UniProtKB/TrEMBL
  Znf_LIM UniProtKB/TrEMBL
NCBI Gene Lims1 ENTREZGENE
PANTHER LIM AND SENESCENT CELL ANTIGEN-LIKE-CONTAINING DOMAIN PROTEIN UniProtKB/TrEMBL
  LIM AND SENESCENT CELL ANTIGEN-LIKE-CONTAINING DOMAIN PROTEIN 1 UniProtKB/TrEMBL
  PTHR24210 UniProtKB/TrEMBL
Pfam LIM UniProtKB/TrEMBL
PIRSF PINCH UniProtKB/TrEMBL
PROSITE LIM_DOMAIN_1 UniProtKB/TrEMBL
  LIM_DOMAIN_2 UniProtKB/TrEMBL
SMART LIM UniProtKB/TrEMBL
Superfamily-SCOP Glucocorticoid receptor-like (DNA-binding domain) UniProtKB/TrEMBL
UniProt I3MQ88 ENTREZGENE, UniProtKB/TrEMBL
  I3NAG1 ENTREZGENE, UniProtKB/TrEMBL