Pkdrej (polycystin family receptor for egg jelly) - Rat Genome Database

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Gene: Pkdrej (polycystin family receptor for egg jelly) Ictidomys tridecemlineatus
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Symbol: Pkdrej
Name: polycystin family receptor for egg jelly
RGD ID: 12641907
Description: ENCODES a protein that exhibits calcium channel activity (inferred); calcium ion binding (inferred); INVOLVED IN regulation of acrosome reaction (ortholog); ASSOCIATED WITH intellectual disability (ortholog); Phelan-McDermid syndrome (ortholog); FOUND IN sperm plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: polycystin (PKD) family receptor for egg jelly
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049453,641,786 - 3,652,767 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366293,645,579 - 3,651,827 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366293,641,786 - 3,651,827 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Pkdrej
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049453,641,786 - 3,652,767 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366293,645,579 - 3,651,827 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366293,641,786 - 3,651,827 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PKDREJ
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382246,255,663 - 46,263,343 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2246,255,663 - 46,263,343 (-)EnsemblGRCh38hg38GRCh38
GRCh372246,651,560 - 46,659,240 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362245,030,224 - 45,037,883 (-)NCBINCBI36Build 36hg18NCBI36
Build 342244,972,078 - 44,979,738NCBI
Celera2230,558,945 - 30,566,604 (-)NCBICelera
Cytogenetic Map22q13.31NCBI
HuRef2229,595,594 - 29,603,195 (-)NCBIHuRef
CHM1_12246,610,296 - 46,617,952 (-)NCBICHM1_1
T2T-CHM13v2.02246,740,363 - 46,748,043 (-)NCBIT2T-CHM13v2.0
Pkdrej
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391585,698,877 - 85,705,934 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1585,698,871 - 85,705,935 (-)EnsemblGRCm39 Ensembl
GRCm381585,814,676 - 85,821,733 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1585,814,670 - 85,821,734 (-)EnsemblGRCm38mm10GRCm38
MGSCv371585,645,106 - 85,652,163 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361585,643,119 - 85,649,499 (-)NCBIMGSCv36mm8
Celera1587,946,722 - 87,953,940 (-)NCBICelera
Cytogenetic Map15E2NCBI
cM Map1540.42NCBI
Pkdrej
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87118,788,939 - 118,795,313 (-)NCBIGRCr8
mRatBN7.27116,909,094 - 116,915,468 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7116,909,094 - 116,915,468 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7118,659,894 - 118,666,268 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07120,885,522 - 120,891,896 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07120,855,083 - 120,861,457 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07126,695,498 - 126,701,872 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7126,695,498 - 126,701,872 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07126,406,494 - 126,412,868 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47123,820,836 - 123,827,210 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17123,855,074 - 123,861,440 (-)NCBI
Celera7113,201,150 - 113,207,508 (-)NCBICelera
Cytogenetic Map7q34NCBI
Pkdrej
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541330,378,603 - 30,384,681 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541330,377,627 - 30,384,749 (-)NCBIChiLan1.0ChiLan1.0
PKDREJ
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22356,084,012 - 56,094,545 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12258,782,261 - 58,792,495 (-)NCBINHGRI_mPanPan1
PanPan1.12245,320,969 - 45,328,048 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2245,321,867 - 45,333,429 (-)Ensemblpanpan1.1panPan2
PKDREJ
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11019,914,217 - 19,921,766 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1019,914,721 - 19,920,822 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1019,834,380 - 19,844,271 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01020,645,684 - 20,655,572 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.11020,365,964 - 20,375,852 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01020,678,759 - 20,688,643 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01020,860,574 - 20,870,461 (+)NCBIUU_Cfam_GSD_1.0
PKDREJ
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.153,270,753 - 3,283,058 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.25508,152 - 514,973 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PKDREJ
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11928,728,474 - 28,736,676 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1928,729,375 - 28,736,145 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604596,781,707 - 96,802,150 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pkdrej
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247523,630,908 - 3,632,330 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSSTOT00000029261   ⟹   ENSSTOP00000023324
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049366293,645,579 - 3,651,827 (+)Ensembl
RefSeq Acc Id: XM_040281782   ⟹   XP_040137716
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_0244049453,641,786 - 3,652,767 (+)NCBI
Protein Sequences
Protein RefSeqs XP_040137716 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000023324.2
GenBank Protein KAG3290731 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_040137716   ⟸   XM_040281782
- UniProtKB: I3NG27 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSSTOP00000023324   ⟸   ENSSTOT00000029261
Protein Domains
PLAT   REJ


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000023361 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000029261.2 UniProtKB/TrEMBL
Gene3D-CATH 1.10.287.70 UniProtKB/TrEMBL
  PLAT/LH2 domain UniProtKB/TrEMBL
InterPro PKD/REJ-like UniProtKB/TrEMBL
  PKD1_2_channel UniProtKB/TrEMBL
  PKD_2 UniProtKB/TrEMBL
  PLAT/LH2_dom UniProtKB/TrEMBL
  PLAT/LH2_dom_sf UniProtKB/TrEMBL
  PLAT_polycystin1 UniProtKB/TrEMBL
  Polycystin UniProtKB/TrEMBL
  Polycystin_dom UniProtKB/TrEMBL
  REJ_dom UniProtKB/TrEMBL
NCBI Gene Pkdrej ENTREZGENE
PANTHER POLYCYSTIC KIDNEY DISEASE AND RECEPTOR FOR EGG JELLY-RELATED PROTEIN UniProtKB/TrEMBL
  POLYCYSTIN FAMILY MEMBER UniProtKB/TrEMBL
Pfam PKD_channel UniProtKB/TrEMBL
  PLAT UniProtKB/TrEMBL
  Polycystin_dom UniProtKB/TrEMBL
  REJ UniProtKB/TrEMBL
PRINTS POLYCYSTIN2 UniProtKB/TrEMBL
PROSITE PLAT UniProtKB/TrEMBL
  REJ UniProtKB/TrEMBL
SMART LH2 UniProtKB/TrEMBL
Superfamily-SCOP SSF49723 UniProtKB/TrEMBL
UniProt I3NG27 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-03-21 Pkdrej  polycystin family receptor for egg jelly    polycystin (PKD) family receptor for egg jelly  Symbol and/or name change 5135510 APPROVED