LOC101971629 (core histone macro-H2A.1) - Rat Genome Database

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Pathways
Gene: LOC101971629 (core histone macro-H2A.1) Ictidomys tridecemlineatus
Analyze
Symbol: LOC101971629 (Ensembl: MACROH2A1)
Name: core histone macro-H2A.1 (Ensembl:macroH2A.1 histone)
RGD ID: 12638237
Description: ENCODES a protein that exhibits ADP-D-ribose binding (ortholog); INVOLVED IN dosage compensation by inactivation of X chromosome (ortholog); negative regulation of response to oxidative stress (ortholog); positive regulation of response to oxidative stress (ortholog); PARTICIPATES IN histone modification pathway; ASSOCIATED WITH familial adenomatous polyposis 1 (ortholog); Hereditary Neoplastic Syndromes (ortholog); myelodysplastic syndrome (ortholog); FOUND IN chromatin (ortholog); nucleosome (ortholog); nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: core histone macro-H2A.1, transcript variant X1; core histone macro-H2A.1, transcript variant X2; core histone macro-H2A.1, transcript variant X3; core histone macro-H2A.1, transcript variant X4
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213123,471,582 - 123,531,449 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365972,495,862 - 2,556,603 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365972,496,489 - 2,556,352 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
LOC101971629
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213123,471,582 - 123,531,449 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365972,495,862 - 2,556,603 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365972,496,489 - 2,556,352 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MACROH2A1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385135,334,381 - 135,399,887 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5135,334,381 - 135,399,914 (-)Ensemblhg38GRCh38
GRCh375134,670,071 - 134,735,577 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365134,697,970 - 134,763,476 (-)NCBIBuild 36Build 36hg18NCBI36
Build 345134,697,969 - 134,762,802NCBI
Celera5130,793,877 - 130,859,396 (-)NCBICelera
Cytogenetic Map5q31.1NCBI
HuRef5129,857,754 - 129,923,276 (-)NCBIHuRef
CHM1_15134,102,741 - 134,168,247 (-)NCBICHM1_1
T2T-CHM13v2.05135,861,569 - 135,927,059 (-)NCBIT2T-CHM13v2.0
Macroh2a1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391356,221,435 - 56,283,439 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1356,221,432 - 56,284,174 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381356,073,622 - 56,135,626 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1356,073,619 - 56,136,361 (-)Ensemblmm10GRCm38
MGSCv371356,174,983 - 56,236,911 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361356,083,796 - 56,145,137 (-)NCBIMGSCv36mm8
Celera1357,128,470 - 57,190,557 (-)NCBICelera
Cytogenetic Map13B1NCBI
cM Map1330.06NCBI
Macroh2a1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8178,484,340 - 8,547,268 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl178,484,246 - 8,547,257 (+)EnsemblGRCr8
mRatBN7.2178,479,331 - 8,542,071 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl178,479,372 - 8,542,072 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx178,494,921 - 8,557,042 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01710,028,056 - 10,089,627 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0178,491,302 - 8,553,426 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0179,282,109 - 9,344,698 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl179,282,675 - 9,344,678 (+)Ensemblrn6Rnor6.0
Rnor_5.01711,440,567 - 11,502,758 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41714,457,307 - 14,520,963 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera178,563,234 - 8,625,826 (+)NCBICelera
RGSC_v3.11714,457,306 - 14,520,963 (+)NCBI
Cytogenetic Map17p14NCBI
LOC102008188
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540830,497,531 - 30,550,118 (-)Ensembl
ChiLan1.0NW_00495540830,497,531 - 30,550,095 (-)NCBIChiLan1.0ChiLan1.0
LOC100974858
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24130,622,460 - 130,690,055 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15128,762,020 - 128,826,904 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05130,727,065 - 130,791,932 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15136,868,521 - 136,933,834 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5136,868,521 - 136,933,834 (-)EnsemblpanPan2panpan1.1
MACROH2A1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11123,369,957 - 23,448,235 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1123,370,300 - 23,438,219 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1122,118,904 - 22,197,335 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01124,196,790 - 24,265,246 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1124,205,586 - 24,264,536 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11122,875,051 - 22,953,381 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01122,740,600 - 22,819,048 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01123,384,272 - 23,469,034 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
MACROH2A1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2137,534,138 - 137,623,886 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.12137,535,128 - 137,623,886 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22143,054,432 - 143,135,657 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MACROH2A1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12338,113,212 - 38,178,227 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2338,113,195 - 38,168,382 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366603439,737,224 - 39,802,999 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
LOC101706296
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473311,650,537 - 11,715,999 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462473311,650,067 - 11,714,399 (+)NCBIHetGla 1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSSTOT00000014865   ⟹   ENSSTOP00000013316
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365972,495,862 - 2,556,603 (-)Ensembl
Ensembl Acc Id: ENSSTOT00000030252   ⟹   ENSSTOP00000027170
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365972,517,758 - 2,556,603 (-)Ensembl
Ensembl Acc Id: ENSSTOT00000038630   ⟹   ENSSTOP00000028554
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365972,495,862 - 2,556,603 (-)Ensembl
RefSeq Acc Id: XM_005333189   ⟹   XP_005333246
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024407213123,471,582 - 123,531,449 (-)NCBI
SpeTri2.0NW_0049365972,496,489 - 2,556,351 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005333190   ⟹   XP_005333247
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024407213123,471,582 - 123,531,449 (-)NCBI
SpeTri2.0NW_0049365972,496,489 - 2,556,351 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005333191   ⟹   XP_005333248
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024407213123,471,582 - 123,531,449 (-)NCBI
SpeTri2.0NW_0049365972,496,489 - 2,556,352 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005333193   ⟹   XP_005333250
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024407213123,471,582 - 123,531,449 (-)NCBI
SpeTri2.0NW_0049365972,496,489 - 2,556,352 (-)NCBI
Sequence:
RefSeq Acc Id: XP_005333250   ⟸   XM_005333193
- Peptide Label: isoform X4
- UniProtKB: A0A287D4V0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005333247   ⟸   XM_005333190
- Peptide Label: isoform X2
- UniProtKB: I3MNP9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005333246   ⟸   XM_005333189
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_005333248   ⟸   XM_005333191
- Peptide Label: isoform X3
- Sequence:
Ensembl Acc Id: ENSSTOP00000013316   ⟸   ENSSTOT00000014865
Ensembl Acc Id: ENSSTOP00000027170   ⟸   ENSSTOT00000030252
Ensembl Acc Id: ENSSTOP00000028554   ⟸   ENSSTOT00000038630

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000014864 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000014865.3 UniProtKB/TrEMBL
  ENSSTOT00000030252.1 UniProtKB/TrEMBL
  ENSSTOT00000038630.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.20.10 UniProtKB/TrEMBL
  3.40.220.10 UniProtKB/TrEMBL
InterPro Core_histone_macro-H2A UniProtKB/TrEMBL
  Histone-fold UniProtKB/TrEMBL
  Histone_H2A UniProtKB/TrEMBL
  Histone_H2A/H2B/H3 UniProtKB/TrEMBL
  Histone_H2A_C UniProtKB/TrEMBL
  Macro_dom UniProtKB/TrEMBL
  Macro_dom-like UniProtKB/TrEMBL
  Macro_H2A UniProtKB/TrEMBL
NCBI Gene LOC101971629 ENTREZGENE
PANTHER PTHR23430 UniProtKB/TrEMBL
Pfam Histone UniProtKB/TrEMBL
  Histone_H2A_C UniProtKB/TrEMBL
  Macro UniProtKB/TrEMBL
PIRSF Core_histone_macro-H2A UniProtKB/TrEMBL
PRINTS HISTONEH2A UniProtKB/TrEMBL
PROSITE MACRO UniProtKB/TrEMBL
SMART A1pp UniProtKB/TrEMBL
  H2A UniProtKB/TrEMBL
Superfamily-SCOP SSF47113 UniProtKB/TrEMBL
  SSF52949 UniProtKB/TrEMBL
UniProt A0A287D0Z4_ICTTR UniProtKB/TrEMBL
  A0A287D4V0 ENTREZGENE, UniProtKB/TrEMBL
  I3MNP9 ENTREZGENE, UniProtKB/TrEMBL