Mbd6 (methyl-CpG binding domain protein 6) - Rat Genome Database

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Gene: Mbd6 (methyl-CpG binding domain protein 6) Ictidomys tridecemlineatus
Analyze
Symbol: Mbd6
Name: methyl-CpG binding domain protein 6
RGD ID: 12617783
Description: ENCODES a protein that exhibits DNA binding (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); cataract 15 multiple types (ortholog); Charcot-Marie-Tooth disease axonal type 2U (ortholog); FOUND IN fibrillar center (ortholog); nucleoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: methyl-CpG binding domain protein 6, transcript variant X1; methyl-CpG binding domain protein 6, transcript variant X5; methyl-CpG binding domain protein 6, transcript variant X6; methyl-CpG binding domain protein 6, transcript variant X7; methyl-CpG-binding domain protein 6
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494557,191,723 - 57,200,920 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049366461,669,281 - 1,678,512 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Mbd6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494557,191,723 - 57,200,920 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049366461,669,281 - 1,678,512 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MBD6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381257,520,715 - 57,531,545 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1257,520,710 - 57,530,148 (+)EnsemblGRCh38hg38GRCh38
GRCh371257,916,607 - 57,923,931 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361256,202,926 - 56,210,198 (+)NCBINCBI36Build 36hg18NCBI36
Build 341256,202,925 - 56,210,198NCBI
Celera1257,572,491 - 57,579,763 (+)NCBICelera
Cytogenetic Map12q13.3NCBI
HuRef1254,932,323 - 54,961,829 (+)NCBIHuRef
CHM1_11257,884,526 - 57,891,756 (+)NCBICHM1_1
T2T-CHM13v2.01257,488,889 - 57,498,388 (+)NCBIT2T-CHM13v2.0
Mbd6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910127,117,825 - 127,126,738 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl10127,117,825 - 127,124,887 (-)EnsemblGRCm39 Ensembl
GRCm3810127,281,956 - 127,290,869 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10127,281,956 - 127,289,018 (-)EnsemblGRCm38mm10GRCm38
MGSCv3710126,719,012 - 126,725,827 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3610126,684,905 - 126,691,720 (-)NCBIMGSCv36mm8
Celera10129,674,397 - 129,680,132 (-)NCBICelera
Cytogenetic Map10D3NCBI
cM Map1074.5NCBI
Mbd6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8764,992,877 - 65,001,274 (-)NCBIGRCr8
mRatBN7.2763,107,562 - 63,115,841 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl763,107,562 - 63,113,274 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx764,996,836 - 65,002,548 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0767,199,256 - 67,204,968 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0767,000,607 - 67,006,319 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0770,571,435 - 70,580,146 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl770,571,435 - 70,577,147 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0770,745,585 - 70,752,317 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4767,239,304 - 67,245,037 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1767,260,033 - 67,265,767 (-)NCBI
Celera760,248,101 - 60,253,813 (-)NCBICelera
Cytogenetic Map7q22NCBI
Mbd6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554585,238,570 - 5,247,711 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554585,238,570 - 5,247,711 (+)NCBIChiLan1.0ChiLan1.0
MBD6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21036,810,961 - 36,818,440 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11236,807,732 - 36,817,469 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01231,396,733 - 31,404,126 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11231,655,461 - 31,664,638 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1231,655,461 - 31,664,638 (-)Ensemblpanpan1.1panPan2
MBD6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1101,611,462 - 1,620,546 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl101,613,643 - 1,619,745 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha101,674,704 - 1,683,709 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0101,620,536 - 1,629,548 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl101,621,929 - 1,629,548 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1101,598,546 - 1,607,549 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0101,840,434 - 1,849,437 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0101,965,429 - 1,974,435 (+)NCBIUU_Cfam_GSD_1.0
MBD6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl522,791,437 - 22,799,126 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1522,790,220 - 22,799,131 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2524,754,021 - 24,761,374 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MBD6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11153,431,423 - 53,438,719 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1153,432,903 - 53,437,817 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037192,524,292 - 192,532,894 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mbd6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462480210,428,782 - 10,437,777 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462480210,428,782 - 10,437,992 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


RefSeq Acc Id: XM_005335681   ⟹   XP_005335738
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494557,191,723 - 57,200,920 (-)NCBI
SpeTri2.0NW_0049366461,669,281 - 1,678,512 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021733524   ⟹   XP_021589199
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494557,191,723 - 57,200,920 (-)NCBI
SpeTri2.0NW_0049366461,669,281 - 1,678,512 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021733525   ⟹   XP_021589200
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494557,191,723 - 57,200,920 (-)NCBI
SpeTri2.0NW_0049366461,669,281 - 1,678,512 (+)NCBI
Sequence:
RefSeq Acc Id: XM_040280425   ⟹   XP_040136359
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494557,191,723 - 57,200,920 (-)NCBI
RefSeq Acc Id: XM_040280426   ⟹   XP_040136360
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494557,191,723 - 57,200,920 (-)NCBI
RefSeq Acc Id: XM_040280427   ⟹   XP_040136361
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494557,191,723 - 57,200,920 (-)NCBI
RefSeq Acc Id: XR_005731798
Type: NON-CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494557,191,723 - 57,200,920 (-)NCBI
RefSeq Acc Id: XR_005731799
Type: NON-CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494557,191,723 - 57,200,920 (-)NCBI
RefSeq Acc Id: XR_005731800
Type: NON-CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494557,191,723 - 57,200,920 (-)NCBI
RefSeq Acc Id: XR_005731801
Type: NON-CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494557,191,723 - 57,200,920 (-)NCBI
RefSeq Acc Id: XP_005335738   ⟸   XM_005335681
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: XP_021589199   ⟸   XM_021733524
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_021589200   ⟸   XM_021733525
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_040136360   ⟸   XM_040280426
- Peptide Label: isoform X2
RefSeq Acc Id: XP_040136361   ⟸   XM_040280427
- Peptide Label: isoform X3
RefSeq Acc Id: XP_040136359   ⟸   XM_040280425
- Peptide Label: isoform X1


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000001143 UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000001149.3 UniProtKB/TrEMBL
NCBI Gene Mbd6 ENTREZGENE
PANTHER METHYL-CPG BINDING PROTEIN, DROSOPHILA UniProtKB/TrEMBL
  METHYL-CPG-BINDING DOMAIN PROTEIN 6 UniProtKB/TrEMBL
UniProt I3LY26_ICTTR UniProtKB/TrEMBL