Psma6 (proteasome 20S subunit alpha 6) - Rat Genome Database

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Gene: Psma6 (proteasome 20S subunit alpha 6) Ictidomys tridecemlineatus
Analyze
Symbol: Psma6
Name: proteasome 20S subunit alpha 6
RGD ID: 12558794
Description: ENCODES a protein that exhibits NF-kappaB binding (ortholog); RNA binding (ortholog); INVOLVED IN positive regulation of canonical NF-kappaB signal transduction (ortholog); regulation of inflammatory response (ortholog); ASSOCIATED WITH Brain-Lung-Thyroid Syndrome (ortholog); ectodermal dysplasia and immunodeficiency 2 (ortholog); human immunodeficiency virus infectious disease (ortholog); FOUND IN cilium (ortholog); cytoplasm (ortholog); cytosol (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: proteasome subunit alpha 6; proteasome subunit alpha type-6
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864045,937,259 - 45,961,803 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364949,443,108 - 9,463,397 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049364949,443,176 - 9,467,697 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Psma6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864045,937,259 - 45,961,803 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364949,443,108 - 9,463,397 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049364949,443,176 - 9,467,697 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PSMA6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381435,278,558 - 35,317,493 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1435,278,633 - 35,317,493 (+)Ensemblhg38GRCh38
GRCh371435,747,764 - 35,786,699 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361434,831,325 - 34,856,431 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341434,831,324 - 34,856,429NCBI
Celera1415,625,404 - 15,650,528 (+)NCBICelera
Cytogenetic Map14q13.2NCBI
HuRef1415,875,787 - 15,900,913 (+)NCBIHuRef
CHM1_11435,761,317 - 35,786,430 (+)NCBICHM1_1
T2T-CHM13v2.01429,466,162 - 29,505,113 (+)NCBIT2T-CHM13v2.0
Psma6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391255,431,007 - 55,465,244 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1255,431,007 - 55,465,239 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381255,384,222 - 55,418,459 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1255,384,222 - 55,418,454 (+)Ensemblmm10GRCm38
MGSCv371256,499,812 - 56,519,446 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361256,317,027 - 56,336,581 (+)NCBIMGSCv36mm8
Celera1256,548,065 - 56,567,699 (+)NCBICelera
Cytogenetic Map12C1NCBI
cM Map1223.94NCBI
Psma6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8678,500,676 - 78,531,693 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl678,500,736 - 78,531,717 (+)EnsemblGRCr8
mRatBN7.2672,765,534 - 72,796,554 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl672,765,473 - 72,796,554 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx673,199,417 - 73,216,739 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0673,505,773 - 73,523,097 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0672,934,448 - 72,951,769 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0676,174,460 - 76,205,429 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl676,174,452 - 76,205,426 (+)Ensemblrn6Rnor6.0
Rnor_5.0685,711,990 - 85,742,474 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4675,649,844 - 75,667,404 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera671,619,646 - 71,637,029 (+)NCBICelera
RGSC_v3.1675,652,972 - 75,670,527 (+)NCBI
Cytogenetic Map6q23NCBI
Psma6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540925,750,270 - 25,787,533 (-)Ensembl
ChiLan1.0NW_00495540925,751,578 - 25,787,533 (-)NCBIChiLan1.0ChiLan1.0
PSMA6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21536,604,909 - 36,630,164 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11435,821,412 - 35,846,667 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01416,044,300 - 16,069,521 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11434,227,495 - 34,252,354 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1434,214,271 - 34,252,347 (+)EnsemblpanPan2panpan1.1
PSMA6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1814,010,899 - 14,038,141 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl814,010,939 - 14,038,134 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha813,807,535 - 13,834,775 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0814,116,970 - 14,144,066 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl814,117,011 - 14,144,063 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1813,818,618 - 13,845,898 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0813,883,420 - 13,910,936 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0814,173,313 - 14,200,558 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
PSMA6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl764,578,243 - 64,616,491 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1764,578,247 - 64,603,351 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2769,487,814 - 69,525,983 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PSMA6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12412,099,804 - 12,127,477 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2412,099,937 - 12,127,309 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660531,062,970 - 1,090,568 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Psma6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248381,449,266 - 1,486,382 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248381,449,362 - 1,474,597 (-)NCBIHetGla 1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSSTOT00000011773   ⟹   ENSSTOP00000010562
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049364949,443,108 - 9,463,397 (+)Ensembl
RefSeq Acc Id: XM_040275361   ⟹   XP_040131295
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440864045,937,259 - 45,961,803 (+)NCBI
Protein Sequences
Protein RefSeqs XP_040131295 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000010562.3
GenBank Protein KAG3261091 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_040131295   ⟸   XM_040275361
Ensembl Acc Id: ENSSTOP00000010562   ⟸   ENSSTOT00000011773
Protein Domains
Proteasome alpha-type subunits


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000011774 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000011773.3 UniProtKB/TrEMBL
Gene3D-CATH 3.60.20.10 UniProtKB/TrEMBL
InterPro Ntn_hydrolases_N UniProtKB/TrEMBL
  Proteasome_alpha UniProtKB/TrEMBL
  Proteasome_alpha-type UniProtKB/TrEMBL
  Proteasome_asu_N UniProtKB/TrEMBL
  Proteasome_sua/b UniProtKB/TrEMBL
NCBI Gene Psma6 ENTREZGENE
PANTHER PROTEASOME SUBUNIT ALPHA/BETA UniProtKB/TrEMBL
Pfam Proteasome UniProtKB/TrEMBL
  Proteasome_A_N UniProtKB/TrEMBL
PROSITE PROTEASOME_ALPHA_1 UniProtKB/TrEMBL
  PROTEASOME_ALPHA_2 UniProtKB/TrEMBL
SMART Proteasome_A_N UniProtKB/TrEMBL
Superfamily-SCOP SSF56235 UniProtKB/TrEMBL
UniProt I3MHZ0_ICTTR UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-09-03 Psma6  proteasome 20S subunit alpha 6  Psma6  proteasome subunit alpha 6  Symbol and/or name change 5135510 APPROVED