Ranbp2 (RAN binding protein 2) - Rat Genome Database

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Gene: Ranbp2 (RAN binding protein 2) Ictidomys tridecemlineatus
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Symbol: Ranbp2
Name: RAN binding protein 2
RGD ID: 12501606
Description: ENCODES a protein that exhibits peptidyl-prolyl cis-trans isomerase activity (ortholog); protein-containing complex binding (ortholog); INVOLVED IN cytoplasmic pattern recognition receptor signaling pathway (ortholog); intracellular glucose homeostasis (ortholog); negative regulation of innate immune response (ortholog); PARTICIPATES IN CRM1 export pathway; mitochondria transport pathway; ASSOCIATED WITH Alpers-Huttenlocher syndrome (ortholog); anodontia (ortholog); autism spectrum disorder (ortholog); FOUND IN cytoplasmic periphery of the nuclear pore complex (ortholog); nuclear envelope (ortholog); nuclear pore (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: E3 SUMO-protein ligase RanBP2; LOC101974817
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629292,063,973 - 92,136,842 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936829261,129 - 332,999 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936829261,017 - 333,910 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Ranbp2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629292,063,973 - 92,136,842 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936829261,129 - 332,999 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936829261,017 - 333,910 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RANBP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382108,719,482 - 109,842,301 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2108,719,482 - 108,785,810 (+)Ensemblhg38GRCh38
GRCh372109,335,938 - 109,402,265 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362108,702,369 - 108,768,699 (+)NCBIBuild 36Build 36hg18NCBI36
Build 342108,794,454 - 108,859,768NCBI
Celera2103,645,916 - 103,712,243 (+)NCBICelera
Cytogenetic Map2q13NCBI
HuRef2102,934,349 - 103,000,733 (+)NCBIHuRef
CHM1_12109,340,280 - 109,406,595 (+)NCBICHM1_1
T2T-CHM13v2.02109,180,084 - 110,303,989 (+)NCBIT2T-CHM13v2.0
Ranbp2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391058,282,674 - 58,329,977 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1058,282,742 - 58,330,178 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381058,446,852 - 58,494,155 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1058,446,920 - 58,494,356 (+)Ensemblmm10GRCm38
MGSCv371057,909,600 - 57,956,903 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361057,842,209 - 57,889,512 (+)NCBIMGSCv36mm8
Celera1059,184,895 - 59,203,874 (+)NCBICelera
Celera712,211,992 - 12,212,429 (+)NCBICelera
Cytogenetic Map10B4NCBI
cM Map1029.34NCBI
Ranbp2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82026,984,520 - 27,036,573 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl2026,985,275 - 27,036,571 (+)EnsemblGRCr8
mRatBN7.22026,442,156 - 26,493,481 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2026,442,217 - 26,493,481 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx2027,444,577 - 27,495,869 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02026,830,924 - 26,882,082 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02027,578,942 - 27,630,203 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.02028,365,538 - 28,375,676 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.02028,027,054 - 28,076,664 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2028,365,988 - 28,375,791 (+)Ensemblrn6Rnor6.0
Rnor_6.0 Ensembl2028,027,054 - 28,076,664 (+)Ensemblrn6Rnor6.0
Rnor_5.02030,181,409 - 30,191,111 (+)NCBIRnor_5.0Rnor_5.0rn5
Rnor_5.02029,846,539 - 29,896,149 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.42037,271,467 - 37,322,723 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera2027,892,535 - 27,943,825 (+)NCBICelera
Cytogenetic Map20q11NCBI
Ranbp2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495547012,180,544 - 12,249,555 (+)Ensembl
ChiLan1.0NW_00495547012,180,426 - 12,247,737 (+)NCBIChiLan1.0ChiLan1.0
LOC100989340
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21220,849,954 - 20,915,591 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A20,852,719 - 20,920,058 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A94,961,024 - 95,029,437 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A110,010,961 - 110,039,769 (+)NCBIPanPan1.1PanPan1.1panPan2
RANBP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11035,088,175 - 35,181,248 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1035,088,872 - 35,181,129 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1035,010,394 - 35,103,514 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01035,940,061 - 36,033,454 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1035,940,082 - 36,033,437 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11035,669,581 - 35,762,815 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01035,952,703 - 36,045,859 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01036,144,312 - 36,238,211 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
LOC100511376
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl347,531,359 - 47,601,495 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1347,531,362 - 47,601,328 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2349,693,982 - 49,735,050 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103241220
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11412,250,986 - 12,318,801 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1412,251,007 - 12,319,735 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660807,392,456 - 7,462,274 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
LOC101698338
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474911,862,760 - 11,923,958 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462474911,862,670 - 11,923,291 (+)NCBIHetGla 1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSSTOT00000028957   ⟹   ENSSTOP00000020580
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_004936829261,129 - 332,999 (+)Ensembl
RefSeq Acc Id: XM_040270882   ⟹   XP_040126816
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440629292,063,973 - 92,136,842 (-)NCBI
Protein Sequences
Protein RefSeqs XP_040126816 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000020580.2
RefSeq Acc Id: XP_040126816   ⟸   XM_040270882
- UniProtKB: I3N884 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSSTOP00000020580   ⟸   ENSSTOT00000028957
Protein Domains
PPIase cyclophilin-type   RanBD1   RanBP2-type


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000019518 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000028957.2 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.10 UniProtKB/TrEMBL
  2.30.29.30 UniProtKB/TrEMBL
  2.40.100.10 UniProtKB/TrEMBL
  Zinc finger, RanBP2-type UniProtKB/TrEMBL
InterPro Cyclophilin-like_dom_sf UniProtKB/TrEMBL
  Cyclophilin-type_PPIase_CS UniProtKB/TrEMBL
  Cyclophilin-type_PPIase_dom UniProtKB/TrEMBL
  IR1-M UniProtKB/TrEMBL
  PH-like_dom_sf UniProtKB/TrEMBL
  Ran_bind_dom UniProtKB/TrEMBL
  RanBP1-like UniProtKB/TrEMBL
  TPR-like_helical_dom_sf UniProtKB/TrEMBL
  TPR_repeat UniProtKB/TrEMBL
  Znf_RanBP2 UniProtKB/TrEMBL
  Znf_RanBP2_sf UniProtKB/TrEMBL
NCBI Gene Ranbp2 ENTREZGENE
PANTHER E3 SUMO-PROTEIN LIGASE RANBP2 UniProtKB/TrEMBL
  PTHR23138 UniProtKB/TrEMBL
Pfam IR1-M UniProtKB/TrEMBL
  Pro_isomerase UniProtKB/TrEMBL
  Ran_BP1 UniProtKB/TrEMBL
  zf-RanBP UniProtKB/TrEMBL
PRINTS CSAPPISMRASE UniProtKB/TrEMBL
PROSITE CSA_PPIASE_1 UniProtKB/TrEMBL
  CSA_PPIASE_2 UniProtKB/TrEMBL
  RANBD1 UniProtKB/TrEMBL
  TPR UniProtKB/TrEMBL
  ZF_RANBP2_1 UniProtKB/TrEMBL
  ZF_RANBP2_2 UniProtKB/TrEMBL
SMART RanBD UniProtKB/TrEMBL
  TPR UniProtKB/TrEMBL
  ZnF_RBZ UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/TrEMBL
  SSF48452 UniProtKB/TrEMBL
  SSF50891 UniProtKB/TrEMBL
  SSF90209 UniProtKB/TrEMBL
UniProt I3N884 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-26 Ranbp2  RAN binding protein 2  LOC101974817  E3 SUMO-protein ligase RanBP2  Symbol and/or name change 5135510 APPROVED
2017-07-13 LOC101974817  E3 SUMO-protein ligase RanBP2  Ranbp2  RAN binding protein 2  Symbol and/or name change 5135510 APPROVED