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Gene: Srebf1 (sterol regulatory element binding transcription factor 1) Ictidomys tridecemlineatus

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Symbol:

Srebf1

Name:

sterol regulatory element binding transcription factor 1

RGD ID:

12465536

Description:

ENCODES a protein that exhibits chromatin binding (ortholog); protein-containing complex binding (ortholog); sequence-specific DNA binding (ortholog); INVOLVED IN cellular response to fatty acid (ortholog); cellular response to insulin stimulus (ortholog); cholesterol metabolic process (ortholog); PARTICIPATES IN mTOR signaling pathway; sterol regulatory element-binding protein signaling pathway; ASSOCIATED WITH alcoholic hepatitis (ortholog); atherosclerosis (ortholog); autistic disorder (ortholog); FOUND IN protein-containing complex (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

sterol regulatory element binding transcription factor 1, transcript variant X1; sterol regulatory element binding transcription factor 1, transcript variant X2; sterol regulatory element-binding protein 1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	61,447,521 - 61,458,579 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936741	1,406,521 - 1,419,776 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936741	1,408,669 - 1,419,717 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

alcoholic hepatitis (ISO)

atherosclerosis (ISO)

autistic disorder (ISO)

Birt-Hogg-Dube syndrome (ISO)

common variable immunodeficiency 2 (ISO)

coronary artery disease (ISO)

Diabetic Nephropathies (ISO)

diabetic neuropathy (ISO)

disease of metabolism (ISO)

end stage renal disease (ISO)

Experimental Diabetes Mellitus (ISO)

Experimental Liver Cirrhosis (ISO)

familial hyperlipidemia (ISO)

Fetal Growth Retardation (ISO)

genetic disease (ISO)

hepatocellular carcinoma (ISO)

Hypercholesterolemia (ISO)

Hypertriglyceridemia (ISO)

Ichthyosis Follicularis, Atrichia, and Photophobia Syndrome 2 (ISO)

ichthyosis follicularis-alopecia-photophobia syndrome 1 (ISO)

Insulin Resistance (ISO)

Joubert syndrome (ISO)

kidney disease (ISO)

lipid storage disease (ISO)

metabolic dysfunction and alcohol associated liver disease (ISO)

metabolic dysfunction-associated steatohepatitis (ISO)

metabolic dysfunction-associated steatotic liver disease (ISO)

Metabolic Syndrome (ISO)

obesity (ISO)

Potocki-Lupski syndrome (ISO)

Smith-Magenis syndrome (ISO)

steatotic liver disease (ISO)

type 2 diabetes mellitus (ISO)

Urban Schosser Spohn Syndrome (ISO)

Viral Myocarditis (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cellular response to fatty acid (ISO)

cellular response to insulin stimulus (ISO)

cellular response to starvation (IEA)

cholesterol biosynthetic process (IEA)

cholesterol metabolic process (IEA,ISO)

circadian rhythm (IEA)

fat cell differentiation (IEA)

insulin receptor signaling pathway (IEA)

insulin secretion (IEA)

intracellular receptor signaling pathway (IEA)

lipid biosynthetic process (IEA)

lipid metabolic process (IEA)

lung development (ISO)

mRNA transcription by RNA polymerase II (IEA)

negative regulation of insulin secretion (IEA)

negative regulation of transcription by RNA polymerase II (IEA)

negative regulation of triglyceride metabolic process (IEA)

positive regulation of cholesterol biosynthetic process (IEA)

positive regulation of DNA-templated transcription (IEA,ISO)

positive regulation of innate immune response (ISO)

positive regulation of lipid biosynthetic process (ISO)

positive regulation of miRNA transcription (IEA)

positive regulation of transcription by RNA polymerase II (IEA)

positive regulation of triglyceride biosynthetic process (IEA,ISO)

regulation of DNA-templated transcription (IEA,ISO)

regulation of fatty acid metabolic process (IEA)

regulation of heart rate by chemical signal (IEA)

regulation of insulin secretion (IEA)

regulation of mitophagy (IEA)

regulation of protein stability (IEA)

regulation of protein targeting to mitochondrion (IEA)

regulation of transcription by RNA polymerase II (IEA)

response to cAMP (ISO)

response to ethanol (ISO)

response to fatty acid (ISO)

response to food (ISO)

response to fructose (ISO)

response to glucagon (ISO)

response to glucose (IEA)

response to lipid (ISO)

response to nutrient (ISO)

response to peptide hormone (ISO)

response to progesterone (ISO)

response to retinoic acid (ISO)

response to xenobiotic stimulus (ISO)

SREBP signaling pathway (IEA)

steroid metabolic process (IEA)

transcription by RNA polymerase II (IEA)

Cellular Component

cytoplasm (IEA)

cytoplasmic vesicle (IEA)

endoplasmic reticulum (IEA)

endoplasmic reticulum membrane (IEA)

ER to Golgi transport vesicle membrane (IEA)

Golgi apparatus (IEA)

Golgi membrane (IEA)

membrane (IEA)

nucleoplasm (IEA)

nucleus (IEA)

protein-containing complex (ISO)

Molecular Function

chromatin binding (IEA,ISO)

DNA binding (IEA)

DNA-binding transcription activator activity, RNA polymerase II-specific (IEA)

DNA-binding transcription factor activity (IEA)

DNA-binding transcription factor activity, RNA polymerase II-specific (IEA)

nuclear receptor activity (IEA)

protein binding (ISO)

protein dimerization activity (IEA)

protein kinase binding (IEA)

protein-containing complex binding (ISO)

RNA polymerase II cis-regulatory region sequence-specific DNA binding (IEA)

RNA polymerase II transcription regulatory region sequence-specific DNA binding (IEA)

sequence-specific DNA binding (IEA,ISO)

sequence-specific double-stranded DNA binding (IEA)

sterol response element binding (IEA)

transcription coregulator binding (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

mTOR signaling pathway (ISO)

sterol regulatory element-binding protein signaling pathway (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Srebf1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	61,447,521 - 61,458,579 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936741	1,406,521 - 1,419,776 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936741	1,408,669 - 1,419,717 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SREBF1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	17	17,811,334 - 17,836,986 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	17	17,810,399 - 17,837,002 (-)	Ensembl			hg38	GRCh38
GRCh37	17	17,714,648 - 17,740,300 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	17	17,656,111 - 17,681,050 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	17	17,656,110 - 17,681,050	NCBI
Celera	17	18,654,135 - 18,680,982 (-)	NCBI		Celera
Cytogenetic Map	17	p11.2	NCBI
HuRef	17	17,466,908 - 17,494,061 (-)	NCBI		HuRef
CHM1_1	17	17,723,458 - 17,749,109 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	17	17,757,927 - 17,783,669 (-)	NCBI		T2T-CHM13v2.0

Srebf1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	11	60,089,910 - 60,113,407 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	11	60,089,915 - 60,113,407 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	11	60,199,084 - 60,224,186 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	11	60,199,089 - 60,222,581 (-)	Ensembl			mm10	GRCm38
MGSCv37	11	60,012,591 - 60,034,106 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	11	60,015,284 - 60,036,799 (-)	NCBI		MGSCv36	mm8
Celera	11	66,655,030 - 66,676,425 (+)	NCBI		Celera
Cytogenetic Map	11	B2	NCBI
cM Map	11	37.81	NCBI

Srebf1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	10	45,507,152 - 45,529,164 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	10	45,507,152 - 45,529,164 (-)	Ensembl				GRCr8
mRatBN7.2	10	45,007,637 - 45,029,650 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	45,007,637 - 45,029,650 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	10	49,707,833 - 49,729,854 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	49,198,201 - 49,220,219 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	44,701,803 - 44,723,821 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	10	46,570,996 - 46,593,021 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	46,570,996 - 46,593,009 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	10	46,326,015 - 46,348,035 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	10	46,461,684 - 46,483,646 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	10	44,264,866 - 44,286,830 (-)	NCBI		Celera
Cytogenetic Map	10	q22	NCBI

Srebf1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955577	171,425 - 186,046 (+)	Ensembl
ChiLan1.0	NW_004955577	171,425 - 183,669 (+)	NCBI	ChiLan1.0	ChiLan1.0

SREBF1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	19	52,328,005 - 52,355,769 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	17	57,040,217 - 57,065,965 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	17	33,458,196 - 33,484,643 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	17	38,405,794 - 38,432,045 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	17	38,405,794 - 38,432,045 (+)	Ensembl			panPan2	panpan1.1

SREBF1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	5	41,663,809 - 41,686,764 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	5	41,663,773 - 41,686,776 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	5	41,802,335 - 41,825,236 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	5	41,769,693 - 41,792,654 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	5	41,769,687 - 41,925,702 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	5	41,737,352 - 41,760,245 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	5	41,684,736 - 41,707,631 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	5	41,876,687 - 41,899,587 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

SREBF1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	12	60,733,907 - 60,751,267 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	12	60,733,967 - 60,750,951 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

SREBF1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	16	16,847,603 - 16,874,239 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	16	16,845,491 - 16,859,554 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666059	4,037,449 - 4,063,735 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Srebf1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624849	3,602,261 - 3,623,465 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624849	3,602,103 - 3,623,922 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005339453	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_013364809	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040269644	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040269645	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010000662	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSSTOT00000014940 ⟹ ENSSTOP00000013385

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936741	1,406,521 - 1,419,776 (-)	Ensembl

Ensembl Acc Id:

ENSSTOT00000031516 ⟹ ENSSTOP00000029269

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936741	1,406,521 - 1,419,776 (-)	Ensembl

RefSeq Acc Id:

XM_005339453 ⟹ XP_005339510

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405602	61,447,521 - 61,458,579 (+)	NCBI
SpeTri2.0	NW_004936741	1,408,669 - 1,419,717 (-)	NCBI

Sequence:

show sequence

TCTGAGGCGCTCAGCCGGCTTTAAAACTCCGCCGAGCCTTGACAGGTGAAGTCGTCGCGGGGAC
GACGCGGTCAGAGCCAACCGCCTGGACGCCCCGAGGGGGCGGGGGGCGCGCGCTACGGAGCCAT
GGATTGCACGTTCGAAGACATGCTCCAGCTCATCAACAACCAAGACAGCGACTTCCCTGGCCTG
TTTGATCCACCCTATGCTGGGGGTGGGGCAGGGGACACAGAGCCTGCCAGCCCCAGTGCCAGTT
CCCCAGGCAGCTTGTCTCCGTCTCCTGCCTCACTGAGCTCCCCTTTGGAAGCCTTCCTGGGGGA
CCCTAAGGCGGCATCCCCACCTTTGTCCCCTCCCCAGTCTGCACCCACCCCCTTGAACATGTAC
CCATCTGTGTCCCCCTTCTCCCCTGGTCCTGGTATCAAAGAAGAGCCAGTGCCACTAACCATCC
TGCAGCCCCCTACCCCACAACCCCTGTCGGGGACTCTCCTGCCCCAGAGTTTTGCATCCTCAGC
CCCCCCACAGTTCAACTCAGCCCCTGTGTTGGGTTACTCCAACCTTCCTGGAAGCTTCTCAGCA
GGGACCCCTCCTGGGAGCACCCAGCAGCCGCTGCCTGGCCTGCCACTGGCTTCCCCGCCAGGGG
TCCCACCTGTCTCCTTGCATAGCCAGGTCCAGAGTGCGGCCCCCCAGCAGCTGCTGACAGCCAC
AGCGGCCCCTGGAACGACCACTGTAACTTCACAGATCCAGCAGGTCCCGGTCCTGCTGCAGCCC
CACTTCATCAAGGCAGACTCCCTGCTCCTGACCACCATGAAGACCGATGTGGGGGCCACTGTGA
AGGCTGCGGGTATCAGCTCCCTGGCCCCCGGCACAGCTGTACAGACAGCGCCCTTGCAGACCCT
GGTGAGTGGCGGAACCATCCTGGCCACAGTCCCACTGGTTGTGGACACTGACAAGCTGCCCATC
AACCGGTTGGCAGCCGGCAGCAAGGCTGCGGGCTCAGCCCAGAGCCGTGGCGAGAAGCGCACAG
CCCACAATGCCATCGAGAAGCGCTACCGCTCTTCCATCAACGACAAGATAGTGGAGCTCAAGGA
CCTGGTGGTGGGCCCCGAGGCAAAGCTGAATAAGTCTGCTGTCTTGCGCAAGGCCATCGACTAC
ATCCGCTTCTTACAACACAGCAACCAGAAACTCAAGCAGGAGAACCTAAGTCTGCGAACTGCTG
CCCACAAGAGCAAATCACTAAAGGATCTGGTGTCCACTTGCAGCAGTAAAGGAAACACAGATGT
GCCCATGGAGGGTGTGAAGACTGAGCTGGTGGACACACTGACCCCACCACCTTCAGATGCCGGC
TCACCCTCCCAGAGCAGCCCCTTGTCCCTTGGCAGCCGGGGTAGTGGCAGTGGTGGCAGCAGCA
GTGACTCGGAGCCTGACAGCCCAGTCTTTGAGGACAGCCAGGTGAAGCCAGAACAGCTGTCATC
TCCCCACAGCCTGGGCATGCTGGACCGCTCCCGCCTGGCCCTGTGCACACTTGTCTTCCTTTGT
CTGTCCTGTAACCCCCTGGCCTCCCTGCTGGGTGGCTGGACGCTTCCTGGCCCCTCAGATCCTG
TGGGTATCCACCACAGTTCTGGGCGCAGCATGCTGGGCACTGAGGGCAGAGATGGCCCTGACTG
GGCCCAGTGGCTGCTGCCCCCTGTGGTCTGGCTGGTCAATGGGCTAGTGGTGCTGGCTTTCTTG
GCATTTCTCTTTGTCTGTGGGGAGCCGGTGACACGGCCCCACTCCGCCCCTGCTGTGAACTTCT
GGAGACATCGCAAGCAGGCTGACCTGGACCTGGCCCGGGGGGACTTCGCCCAGGCTGCTCAGCA
GCTATGGCTGGCCTTGCAGGCGCTGGGCAGGCCCCTGCCCACCTCCCACCTGGACCTGGCCTGC
AGCCTGCTCTGGAACCTCATTCGCCACCTGCTGCAGCGACTCTGGGTGGGCCGCTGGCTGGCCG
GCCATGCTGGGGGCCTGAGAAGGGACTGTACCCTGAGGGCAGACGCACGCACCAGCGCCCGAGA
TGCAGCCCTCGTCTACCATAAGCTGCACCAGCTGCACACCATGGGGAAGTACACGGGTGGGCAC
CTGGCTGCCACCAACCTGGCACTGAGTGCTCTGAACCTGGCAGAGTGTGCGGGGGATGCCGTGT
CCATGGCAACGCTGGCGGAGATCTATGTGGCAGCTGCCCTGAGGGTCAAGACCAGTCTGCCAAG
GGCCCTGCACTTTCTGACACGCTTCTTCCTGAGTAGCGCCCGCCAGGCCTGCCTGGCACACAGT
GGCTCAGTGCCTCTTGCCATGCAGTGGCTCTGCCACCCCGTGGGCCACCGTTTCTTCGTGGATG
GGGACTGGGCCGTGCGCAGTGCCCCGCGGGAAAGCCTGTACAGCTTGGCCGGGAACCCAGTGGA
CCCCCTGGCCCAGGTGACACAGCTGTTCCGTGAACATCTCCTGGAGCGTGCACTGAACTCTGTG
GCCCAGCCCAGCCCCAACCCCAGCCCCGGGTCAGCTGATGGGGACAGGGAATTCTCAGATGCCC
TTGGATACCTGCAGCTGCTGACCAGTTGTTCTGATGCTGCTGGGGCTCCTGCATGCAGCTTCTC
CATCAGCTCTAGCATGGCCGCCACCACCGGCACAGACCCTGTGGCCAAGTGGTGGGGCTCACTG
ACGGCGGTGGTGATTCACTGGCTGCGGCGGGATGAGGAGGCAGCTGAGCGGCTCTACCCCTTGG
TGGAGCACCTGCCCCGTGCCCTGCAGGAGACGGAGAAACCCCTGCCCAAGGCGGCCCTGCACTC
CTTCAAGGCTGCCCGGGCTGTGTTGGGTCGTGGAAAGGCAGAGTCTGGCCCAGCCAGCCTGGCC
ATCTGTGAGAAAGCCAGCGGGTACCTGAGGGACAGCCTGGCCACCACACCAACTGGCAGCTCCA
TTGACAAGGCCATGCAGCTGCTCCTGTGTGACCTGCTCCTCGTGGTCCGCACTAGCCTGTGGAG
GCAGCAGCAGCCCCCAACGTCAGCACAGGTGGCTCAGGGTGCCAGCAGCGGCCCCCAGGCCTCT
GCCCTCGAGCTACGTGGCTTCCAACGGGACCTGAGCGGCCTGAGGTGTCTGGCACAGAGCTTCC
GTCCTGCCATGAGGAGGGTGTTCTTACACGAGGCCACAGCCCGGCTGATGGCAGGGGCCAGCCC
TACCCGGACACACCAACTCTTGGACCGCAGTCTGAGGCGGCGGGCAGGTCCTGGTGGCAAAGGC
GCGGCGGGGGAGCTGGAGCCGCGGCCCACGCGGCGGGAGCACGCAGAAGCTCTGCTACTGGCCT
CCTGCTACCTGCCGCCTGGCTTCCTGTCGGGGCCGGGGCAGCGCGTGGGCATGCTGACCGAGGC
GGCTCGCACGCTTGAGAAGCTGGGCGATCACCGGCTTCTGCACGACTGCCAGCAGATGCTCATG
CGCCTGGGTGGTGGGACTACAGTTACCTCCAGCTAGACCTCCGGCGTCGTCCAGTCTCAGTGTC
CCGGTCTCCACGGCTCACCCGCGGCCGCTCCGTCCCTGAGGGGTGGGAGGCGGGAGGCGCAACC
CACCACCCCAGCCCGCTCCTCAACTTGACAAGCGGCCGTCAGGATGGTGCTGACCTCTGGTGGC
CGATCGGGGAATTACAGGAGCCGAATCGGCCGTGTTCCCCCCACCGCCCTTGCTCTGCAGGCAC
CTTAGTGGCTTTTTCCTCGCTTTTCTAGGGGGAGGAGGGGGTACCTTTCTTTGAGCTGAGGGGG
CCCTTCCCCAAGGTACCTCTTTCCCTTCTGGGGGAAGACTTGTACATAGTGTAGATGGGTGGGC
CCCCGTGGGCCAGCCTCCTTGCCTCGGAGGCTCATGTGCTACTTTTGCAAACTTTATTTTCGTA
GGTTGAGAAGTTTTGTACAGAGAATAAAAAATGACGTTATTTATAA

hide sequence

RefSeq Acc Id:

XM_013364809 ⟹ XP_013220263

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405602	61,447,521 - 61,458,579 (+)	NCBI
SpeTri2.0	NW_004936741	1,408,669 - 1,419,717 (-)	NCBI

Sequence:

show sequence

TCTGAGGCGCTCAGCCGGCTTTAAAACTCCGCCGAGCCTTGACAGGTGAAGTCGTCGCGGGGAC
GACGCGGTCAGAGCCAACCGCCTGGACGCCCCGAGGGGGCGGGGGGCGCGCGCTACGGAGCCAT
GGATTGCACGTTCGAAGACATGCTCCAGCTCATCAACAACCAAGACAGCGACTTCCCTGGCCTG
TTTGATCCACCCTATGCTGGGGGTGGGGCAGGGGACACAGAGCCTGCCAGCCCCAGTGCCAGTT
CCCCAGGCAGCTTGTCTCCGTCTCCTGCCTCACTGAGCTCCCCTTTGGAAGCCTTCCTGGGGGA
CCCTAAGGCGGCATCCCCACCTTTGTCCCCTCCCCAGTCTGCACCCACCCCCTTGAACATGTAC
CCATCTGTGTCCCCCTTCTCCCCTGGTCCTGGTATCAAAGAAGAGCCAGTGCCACTAACCATCC
TGCAGCCCCCTACCCCACAACCCCTGTCGGGGACTCTCCTGCCCCAGAGTTTTGCATCCTCAGC
CCCCCCACAGTTCAACTCAGCCCCTGTGTTGGGTTACTCCAACCTTCCTGGAAGCTTCTCAGCA
GGGACCCCTCCTGGGAGCACCCAGCAGCCGCTGCCTGGCCTGCCACTGGCTTCCCCGCCAGGGG
TCCCACCTGTCTCCTTGCATAGCCAGGTCCAGAGTGCGGCCCCCCAGCAGCTGCTGACAGCCAC
AGCGGCCCCTGGAACGACCACTGTAACTTCACAGATCCAGCAGGTCCCGGTCCTGCTGCAGCCC
CACTTCATCAAGGCAGACTCCCTGCTCCTGACCACCATGAAGACCGATGTGGGGGCCACTGTGA
AGGCTGCGGGTATCAGCTCCCTGGCCCCCGGCACAGCTGTACAGACAGCGCCCTTGCAGACCCT
GGTGAGTGGCGGAACCATCCTGGCCACAGTCCCACTGGTTGTGGACACTGACAAGCTGCCCATC
AACCGGTTGGCAGCCGGCAGCAAGGCTGCGGGCTCAGCCCAGAGCCGTGGCGAGAAGCGCACAG
CCCACAATGCCATCGAGAAGCGCTACCGCTCTTCCATCAACGACAAGATAGTGGAGCTCAAGGA
CCTGGTGGTGGGCCCCGAGGCAAAGCTGAATAAGTCTGCTGTCTTGCGCAAGGCCATCGACTAC
ATCCGCTTCTTACAACACAGCAACCAGAAACTCAAGCAGGAGAACCTAAGTCTGCGAACTGCTG
CCCACAAGAGCACAGAATCACTAAAGGATCTGGTGTCCACTTGCAGCAGTAAAGGAAACACAGA
TGTGCCCATGGAGGGTGTGAAGACTGAGCTGGTGGACACACTGACCCCACCACCTTCAGATGCC
GGCTCACCCTCCCAGAGCAGCCCCTTGTCCCTTGGCAGCCGGGGTAGTGGCAGTGGTGGCAGCA
GCAGTGACTCGGAGCCTGACAGCCCAGTCTTTGAGGACAGCCAGGTGAAGCCAGAACAGCTGTC
ATCTCCCCACAGCCTGGGCATGCTGGACCGCTCCCGCCTGGCCCTGTGCACACTTGTCTTCCTT
TGTCTGTCCTGTAACCCCCTGGCCTCCCTGCTGGGTGGCTGGACGCTTCCTGGCCCCTCAGATC
CTGTGGGTATCCACCACAGTTCTGGGCGCAGCATGCTGGGCACTGAGGGCAGAGATGGCCCTGA
CTGGGCCCAGTGGCTGCTGCCCCCTGTGGTCTGGCTGGTCAATGGGCTAGTGGTGCTGGCTTTC
TTGGCATTTCTCTTTGTCTGTGGGGAGCCGGTGACACGGCCCCACTCCGCCCCTGCTGTGAACT
TCTGGAGACATCGCAAGCAGGCTGACCTGGACCTGGCCCGGGGGGACTTCGCCCAGGCTGCTCA
GCAGCTATGGCTGGCCTTGCAGGCGCTGGGCAGGCCCCTGCCCACCTCCCACCTGGACCTGGCC
TGCAGCCTGCTCTGGAACCTCATTCGCCACCTGCTGCAGCGACTCTGGGTGGGCCGCTGGCTGG
CCGGCCATGCTGGGGGCCTGAGAAGGGACTGTACCCTGAGGGCAGACGCACGCACCAGCGCCCG
AGATGCAGCCCTCGTCTACCATAAGCTGCACCAGCTGCACACCATGGGGAAGTACACGGGTGGG
CACCTGGCTGCCACCAACCTGGCACTGAGTGCTCTGAACCTGGCAGAGTGTGCGGGGGATGCCG
TGTCCATGGCAACGCTGGCGGAGATCTATGTGGCAGCTGCCCTGAGGGTCAAGACCAGTCTGCC
AAGGGCCCTGCACTTTCTGACACGCTTCTTCCTGAGTAGCGCCCGCCAGGCCTGCCTGGCACAC
AGTGGCTCAGTGCCTCTTGCCATGCAGTGGCTCTGCCACCCCGTGGGCCACCGTTTCTTCGTGG
ATGGGGACTGGGCCGTGCGCAGTGCCCCGCGGGAAAGCCTGTACAGCTTGGCCGGGAACCCAGT
GGACCCCCTGGCCCAGGTGACACAGCTGTTCCGTGAACATCTCCTGGAGCGTGCACTGAACTCT
GTGGCCCAGCCCAGCCCCAACCCCAGCCCCGGGTCAGCTGATGGGGACAGGGAATTCTCAGATG
CCCTTGGATACCTGCAGCTGCTGACCAGTTGTTCTGATGCTGCTGGGGCTCCTGCATGCAGCTT
CTCCATCAGCTCTAGCATGGCCGCCACCACCGGCACAGACCCTGTGGCCAAGTGGTGGGGCTCA
CTGACGGCGGTGGTGATTCACTGGCTGCGGCGGGATGAGGAGGCAGCTGAGCGGCTCTACCCCT
TGGTGGAGCACCTGCCCCGTGCCCTGCAGGAGACGGAGAAACCCCTGCCCAAGGCGGCCCTGCA
CTCCTTCAAGGCTGCCCGGGCTGTGTTGGGTCGTGGAAAGGCAGAGTCTGGCCCAGCCAGCCTG
GCCATCTGTGAGAAAGCCAGCGGGTACCTGAGGGACAGCCTGGCCACCACACCAACTGGCAGCT
CCATTGACAAGGCCATGCAGCTGCTCCTGTGTGACCTGCTCCTCGTGGTCCGCACTAGCCTGTG
GAGGCAGCAGCAGCCCCCAACGTCAGCACAGGTGGCTCAGGGTGCCAGCAGCGGCCCCCAGGCC
TCTGCCCTCGAGCTACGTGGCTTCCAACGGGACCTGAGCGGCCTGAGGTGTCTGGCACAGAGCT
TCCGTCCTGCCATGAGGAGGGTGTTCTTACACGAGGCCACAGCCCGGCTGATGGCAGGGGCCAG
CCCTACCCGGACACACCAACTCTTGGACCGCAGTCTGAGGCGGCGGGCAGGTCCTGGTGGCAAA
GGCGCGGCGGGGGAGCTGGAGCCGCGGCCCACGCGGCGGGAGCACGCAGAAGCTCTGCTACTGG
CCTCCTGCTACCTGCCGCCTGGCTTCCTGTCGGGGCCGGGGCAGCGCGTGGGCATGCTGACCGA
GGCGGCTCGCACGCTTGAGAAGCTGGGCGATCACCGGCTTCTGCACGACTGCCAGCAGATGCTC
ATGCGCCTGGGTGGTGGGACTACAGTTACCTCCAGCTAGACCTCCGGCGTCGTCCAGTCTCAGT
GTCCCGGTCTCCACGGCTCACCCGCGGCCGCTCCGTCCCTGAGGGGTGGGAGGCGGGAGGCGCA
ACCCACCACCCCAGCCCGCTCCTCAACTTGACAAGCGGCCGTCAGGATGGTGCTGACCTCTGGT
GGCCGATCGGGGAATTACAGGAGCCGAATCGGCCGTGTTCCCCCCACCGCCCTTGCTCTGCAGG
CACCTTAGTGGCTTTTTCCTCGCTTTTCTAGGGGGAGGAGGGGGTACCTTTCTTTGAGCTGAGG
GGGCCCTTCCCCAAGGTACCTCTTTCCCTTCTGGGGGAAGACTTGTACATAGTGTAGATGGGTG
GGCCCCCGTGGGCCAGCCTCCTTGCCTCGGAGGCTCATGTGCTACTTTTGCAAACTTTATTTTC
GTAGGTTGAGAAGTTTTGTACAGAGAATAAAAAATGACGTTATTTATAA

hide sequence

RefSeq Acc Id:

XM_040269644 ⟹ XP_040125578

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405602	61,447,521 - 61,458,579 (+)	NCBI

RefSeq Acc Id:

XM_040269645 ⟹ XP_040125579

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405602	61,447,521 - 61,458,579 (+)	NCBI

Protein Sequences


Protein RefSeqs	XP_005339510	(Get FASTA)	NCBI Sequence Viewer
	XP_013220263	(Get FASTA)	NCBI Sequence Viewer
	XP_040125578	(Get FASTA)	NCBI Sequence Viewer
	XP_040125579	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000013385.3
	ENSSTOP00000029269.1
GenBank Protein	KAG3270326	(Get FASTA)	NCBI Sequence Viewer
	KAG3270327	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	XP_005339510 ⟸ XM_005339453
- Peptide Label:	isoform X3
- UniProtKB:	I3MNU7 (UniProtKB/TrEMBL)
- Sequence:	show sequence MDCTFEDMLQLINNQDSDFPGLFDPPYAGGGAGDTEPASPSASSPGSLSPSPASLSSPLEAFLG DPKAASPPLSPPQSAPTPLNMYPSVSPFSPGPGIKEEPVPLTILQPPTPQPLSGTLLPQSFASS APPQFNSAPVLGYSNLPGSFSAGTPPGSTQQPLPGLPLASPPGVPPVSLHSQVQSAAPQQLLTA TAAPGTTTVTSQIQQVPVLLQPHFIKADSLLLTTMKTDVGATVKAAGISSLAPGTAVQTAPLQT LVSGGTILATVPLVVDTDKLPINRLAAGSKAAGSAQSRGEKRTAHNAIEKRYRSSINDKIVELK DLVVGPEAKLNKSAVLRKAIDYIRFLQHSNQKLKQENLSLRTAAHKSKSLKDLVSTCSSKGNTD VPMEGVKTELVDTLTPPPSDAGSPSQSSPLSLGSRGSGSGGSSSDSEPDSPVFEDSQVKPEQLS SPHSLGMLDRSRLALCTLVFLCLSCNPLASLLGGWTLPGPSDPVGIHHSSGRSMLGTEGRDGPD WAQWLLPPVVWLVNGLVVLAFLAFLFVCGEPVTRPHSAPAVNFWRHRKQADLDLARGDFAQAAQ QLWLALQALGRPLPTSHLDLACSLLWNLIRHLLQRLWVGRWLAGHAGGLRRDCTLRADARTSAR DAALVYHKLHQLHTMGKYTGGHLAATNLALSALNLAECAGDAVSMATLAEIYVAAALRVKTSLP RALHFLTRFFLSSARQACLAHSGSVPLAMQWLCHPVGHRFFVDGDWAVRSAPRESLYSLAGNPV DPLAQVTQLFREHLLERALNSVAQPSPNPSPGSADGDREFSDALGYLQLLTSCSDAAGAPACSF SISSSMAATTGTDPVAKWWGSLTAVVIHWLRRDEEAAERLYPLVEHLPRALQETEKPLPKAALH SFKAARAVLGRGKAESGPASLAICEKASGYLRDSLATTPTGSSIDKAMQLLLCDLLLVVRTSLW RQQQPPTSAQVAQGASSGPQASALELRGFQRDLSGLRCLAQSFRPAMRRVFLHEATARLMAGAS PTRTHQLLDRSLRRRAGPGGKGAAGELEPRPTRREHAEALLLASCYLPPGFLSGPGQRVGMLTE AARTLEKLGDHRLLHDCQQMLMRLGGGTTVTSS hide sequence

RefSeq Acc Id:

XP_013220263 ⟸ XM_013364809

- Peptide Label:

isoform X2

- Sequence:

show sequence

MDCTFEDMLQLINNQDSDFPGLFDPPYAGGGAGDTEPASPSASSPGSLSPSPASLSSPLEAFLG
DPKAASPPLSPPQSAPTPLNMYPSVSPFSPGPGIKEEPVPLTILQPPTPQPLSGTLLPQSFASS
APPQFNSAPVLGYSNLPGSFSAGTPPGSTQQPLPGLPLASPPGVPPVSLHSQVQSAAPQQLLTA
TAAPGTTTVTSQIQQVPVLLQPHFIKADSLLLTTMKTDVGATVKAAGISSLAPGTAVQTAPLQT
LVSGGTILATVPLVVDTDKLPINRLAAGSKAAGSAQSRGEKRTAHNAIEKRYRSSINDKIVELK
DLVVGPEAKLNKSAVLRKAIDYIRFLQHSNQKLKQENLSLRTAAHKSTESLKDLVSTCSSKGNT
DVPMEGVKTELVDTLTPPPSDAGSPSQSSPLSLGSRGSGSGGSSSDSEPDSPVFEDSQVKPEQL
SSPHSLGMLDRSRLALCTLVFLCLSCNPLASLLGGWTLPGPSDPVGIHHSSGRSMLGTEGRDGP
DWAQWLLPPVVWLVNGLVVLAFLAFLFVCGEPVTRPHSAPAVNFWRHRKQADLDLARGDFAQAA
QQLWLALQALGRPLPTSHLDLACSLLWNLIRHLLQRLWVGRWLAGHAGGLRRDCTLRADARTSA
RDAALVYHKLHQLHTMGKYTGGHLAATNLALSALNLAECAGDAVSMATLAEIYVAAALRVKTSL
PRALHFLTRFFLSSARQACLAHSGSVPLAMQWLCHPVGHRFFVDGDWAVRSAPRESLYSLAGNP
VDPLAQVTQLFREHLLERALNSVAQPSPNPSPGSADGDREFSDALGYLQLLTSCSDAAGAPACS
FSISSSMAATTGTDPVAKWWGSLTAVVIHWLRRDEEAAERLYPLVEHLPRALQETEKPLPKAAL
HSFKAARAVLGRGKAESGPASLAICEKASGYLRDSLATTPTGSSIDKAMQLLLCDLLLVVRTSL
WRQQQPPTSAQVAQGASSGPQASALELRGFQRDLSGLRCLAQSFRPAMRRVFLHEATARLMAGA
SPTRTHQLLDRSLRRRAGPGGKGAAGELEPRPTRREHAEALLLASCYLPPGFLSGPGQRVGMLT
EAARTLEKLGDHRLLHDCQQMLMRLGGGTTVTSS

hide sequence

RefSeq Acc Id:	XP_040125579 ⟸ XM_040269645
- Peptide Label:	isoform X4

RefSeq Acc Id:	XP_040125578 ⟸ XM_040269644
- Peptide Label:	isoform X1
- UniProtKB:	A0A287D6V5 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSSTOP00000029269 ⟸ ENSSTOT00000031516

Ensembl Acc Id:

ENSSTOP00000013385 ⟸ ENSSTOT00000014940

Protein Domains

bHLH

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000014939	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000014940.3	UniProtKB/TrEMBL
	ENSSTOT00000031516.1	UniProtKB/TrEMBL
Gene3D-CATH	4.10.280.10	UniProtKB/TrEMBL
InterPro	bHLH_dom	UniProtKB/TrEMBL
	HLH_DNA-bd_sf	UniProtKB/TrEMBL
KEGG Report	iti:101964237	UniProtKB/TrEMBL
NCBI Gene	Srebf1	ENTREZGENE
PANTHER	STEROL REGULATORY ELEMENT-BINDING PROTEIN	UniProtKB/TrEMBL
	STEROL REGULATORY ELEMENT-BINDING PROTEIN 1	UniProtKB/TrEMBL
Pfam	HLH	UniProtKB/TrEMBL
PROSITE	BHLH	UniProtKB/TrEMBL
SMART	HLH	UniProtKB/TrEMBL
Superfamily-SCOP	SSF47459	UniProtKB/TrEMBL
UniProt	A0A287D6V5	ENTREZGENE, UniProtKB/TrEMBL
	I3MNU7	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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