Defb1 (defensin beta 1) - Rat Genome Database

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Gene: Defb1 (defensin beta 1) Ictidomys tridecemlineatus
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Symbol: Defb1
Name: defensin beta 1
RGD ID: 12465255
Description: ENCODES a protein that exhibits CCR6 chemokine receptor binding (ortholog); double-stranded DNA binding (ortholog); identical protein binding (ortholog); INVOLVED IN antimicrobial humoral immune response mediated by antimicrobial peptide (ortholog); calcium-mediated signaling (ortholog); defense response to bacterium (ortholog); ASSOCIATED WITH Actinobacillus Infections (ortholog); asthma (ortholog); chronic obstructive pulmonary disease (ortholog); FOUND IN extracellular space (ortholog); membrane (ortholog); microvesicle (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: beta-defensin 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049434,780,229 - 4,790,578 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049366154,780,229 - 4,790,516 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Defb1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049434,780,229 - 4,790,578 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049366154,780,229 - 4,790,516 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DEFB1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3886,870,592 - 6,877,936 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl86,870,592 - 6,877,936 (-)Ensemblhg38GRCh38
GRCh3786,728,114 - 6,735,458 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3686,715,507 - 6,722,939 (-)NCBIBuild 36Build 36hg18NCBI36
Build 3486,715,510 - 6,722,939NCBI
Celera86,705,523 - 6,712,945 (-)NCBICelera
Cytogenetic Map8p23.1NCBI
HuRef86,508,241 - 6,515,671 (-)NCBIHuRef
CHM1_186,817,351 - 6,824,768 (-)NCBICHM1_1
T2T-CHM13v2.086,625,781 - 6,633,102 (-)NCBIT2T-CHM13v2.0
Defb1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39822,266,571 - 22,285,201 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl822,266,615 - 22,285,201 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38821,776,555 - 21,795,185 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl821,776,599 - 21,795,185 (+)Ensemblmm10GRCm38
MGSCv37822,887,027 - 22,905,657 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36823,242,144 - 23,260,730 (+)NCBIMGSCv36mm8
Celera823,268,826 - 23,284,384 (+)NCBICelera
Cytogenetic Map8A2NCBI
cM Map810.35NCBI
Defb1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81677,001,326 - 77,016,068 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1677,001,326 - 77,016,068 (-)EnsemblGRCr8
mRatBN7.21670,298,862 - 70,313,604 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1670,298,863 - 70,313,604 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1675,572,581 - 75,587,323 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01679,025,581 - 79,040,295 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01674,275,011 - 74,289,718 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01675,294,385 - 75,309,127 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1675,294,376 - 75,309,176 (-)Ensemblrn6Rnor6.0
Rnor_5.01674,908,901 - 74,923,643 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41674,980,054 - 74,995,445 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1668,171,373 - 68,186,246 (-)NCBICelera
RGSC_v3.11674,980,319 - 74,995,710 (-)NCBI
Cytogenetic Map16q12.5NCBI
LOC102004444
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540353,643,300 - 53,644,505 (+)Ensembl
ChiLan1.0NW_00495540353,643,328 - 53,644,361 (+)NCBIChiLan1.0ChiLan1.0
DEFB1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2721,673,949 - 21,682,991 (-)NCBINHGRI_mPanPan1-v2
Mhudiblu_PPA_v08403,268 - 410,712 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.186,874,235 - 6,881,631 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl86,874,235 - 6,881,631 (-)EnsemblpanPan2panpan1.1
DEFB1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11658,871,018 - 58,881,592 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1658,871,018 - 58,881,592 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1654,396,123 - 54,406,697 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01657,167,155 - 57,177,835 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1657,167,155 - 57,177,835 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11659,031,889 - 59,042,480 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01655,175,446 - 55,186,038 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01655,550,404 - 55,561,006 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
DEFB1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa10.21543,346,359 - 43,356,953 (+)NCBISscrofa10.2Sscrofa10.2susScr3
DEFB1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.186,643,753 - 6,652,209 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl86,643,556 - 6,651,699 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605448,759,956 - 48,767,679 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Defb1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248614,710,687 - 4,718,867 (-)NCBIHetGla 1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005334349 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAESOR010000002 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: XM_005334349   ⟹   XP_005334406
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_0244049434,780,229 - 4,790,578 (-)NCBI
SpeTri2.0NW_0049366154,780,229 - 4,790,516 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005334406 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_005334406   ⟸   XM_005334349
- Sequence:


Additional Information

Database Acc Id Source(s)
NCBI Gene Defb1 ENTREZGENE