Trmt2a (tRNA methyltransferase 2 homolog A) - Rat Genome Database

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Gene: Trmt2a (tRNA methyltransferase 2 homolog A) Ictidomys tridecemlineatus
Analyze
Symbol: Trmt2a
Name: tRNA methyltransferase 2 homolog A
RGD ID: 12454210
Description: ENCODES a protein that exhibits C-methyltransferase activity (inferred); methyltransferase activity (inferred); nucleic acid binding (inferred); INVOLVED IN methylation (inferred); RNA processing (inferred); ASSOCIATED WITH autism spectrum disorder (ortholog); autistic disorder (ortholog); chromosome 22q11.2 deletion syndrome, distal (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: tRNA (uracil-5-)-methyltransferase homolog A
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118138,734,886 - 138,739,581 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366194,014,508 - 4,020,569 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366194,015,072 - 4,020,163 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
Trmt2a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118138,734,886 - 138,739,581 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366194,014,508 - 4,020,569 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366194,015,072 - 4,020,163 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TRMT2A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382220,111,875 - 20,117,226 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2220,111,875 - 20,117,392 (-)EnsemblGRCh38hg38GRCh38
GRCh372220,099,398 - 20,104,749 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362218,479,398 - 18,484,768 (-)NCBINCBI36Build 36hg18NCBI36
Celera223,951,448 - 3,956,818 (-)NCBICelera
Cytogenetic Map22q11.21ENTREZGENE
HuRef223,720,050 - 3,725,479 (-)NCBIHuRef
CHM1_12220,099,073 - 20,104,502 (-)NCBICHM1_1
T2T-CHM13v2.02220,490,925 - 20,496,276 (-)NCBIT2T-CHM13v2.0
Trmt2a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391618,066,747 - 18,072,636 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1618,066,543 - 18,072,636 (+)EnsemblGRCm39 Ensembl
GRCm381618,248,847 - 18,254,772 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1618,248,679 - 18,254,772 (+)EnsemblGRCm38mm10GRCm38
MGSCv371618,248,976 - 18,253,595 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361618,162,242 - 18,167,065 (+)NCBIMGSCv36mm8
Celera1618,821,629 - 18,826,248 (+)NCBICelera
Cytogenetic Map16A3NCBI
cM Map1611.31NCBI
Trmt2a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81196,241,998 - 96,246,719 (-)NCBIGRCr8
mRatBN7.21182,737,689 - 82,742,423 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1182,737,689 - 82,742,336 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1191,466,077 - 91,470,686 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01184,127,305 - 84,131,914 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01183,180,820 - 83,185,429 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01186,885,671 - 86,890,482 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1186,885,626 - 86,890,390 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01189,979,609 - 89,984,427 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41184,731,490 - 84,736,099 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11184,772,087 - 84,776,696 (-)NCBI
Celera1181,514,696 - 81,519,305 (-)NCBICelera
Cytogenetic Map11q23NCBI
Trmt2a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544217,993,434 - 17,997,850 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495544217,993,130 - 17,997,944 (+)NCBIChiLan1.0ChiLan1.0
TRMT2A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22329,738,978 - 29,744,352 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12232,285,632 - 32,291,342 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0222,872,328 - 2,877,732 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12218,544,736 - 18,550,174 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2218,544,736 - 18,550,174 (-)Ensemblpanpan1.1panPan2
TRMT2A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12629,219,549 - 29,224,155 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2629,219,812 - 29,226,233 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2629,178,491 - 29,183,068 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02630,623,618 - 30,628,196 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2630,623,786 - 30,630,273 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12628,671,464 - 28,676,060 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02628,296,828 - 28,301,424 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02629,381,756 - 29,386,414 (+)NCBIUU_Cfam_GSD_1.0
TRMT2A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1451,489,892 - 51,494,190 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11451,489,889 - 51,494,204 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21455,126,931 - 55,131,237 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TRMT2A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1195,622,542 - 5,627,923 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl195,622,630 - 5,627,257 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660851,305,872 - 1,311,254 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Trmt2a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624747722,607 - 727,947 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624747722,901 - 727,979 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSSTOT00000014507   ⟹   ENSSTOP00000012998
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049366194,015,337 - 4,019,870 (-)Ensembl
Ensembl Acc Id: ENSSTOT00000032803   ⟹   ENSSTOP00000031833
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049366194,014,508 - 4,020,569 (-)Ensembl
RefSeq Acc Id: XM_040291076   ⟹   XP_040147010
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405118138,735,085 - 138,739,581 (+)NCBI
RefSeq Acc Id: XM_040291077   ⟹   XP_040147011
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405118138,734,886 - 138,739,581 (+)NCBI
Protein Sequences
Protein RefSeqs XP_040147010 (Get FASTA)   NCBI Sequence Viewer  
  XP_040147011 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000012998.3
  ENSSTOP00000031833.1
GenBank Protein KAG3278624 (Get FASTA)   NCBI Sequence Viewer  
  KAG3278625 (Get FASTA)   NCBI Sequence Viewer  
  KAG3278626 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_040147011   ⟸   XM_040291077
- Peptide Label: isoform X2
RefSeq Acc Id: XP_040147010   ⟸   XM_040291076
- Peptide Label: isoform X1
Ensembl Acc Id: ENSSTOP00000031833   ⟸   ENSSTOT00000032803
Ensembl Acc Id: ENSSTOP00000012998   ⟸   ENSSTOT00000014507
Protein Domains
RRM


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000014487 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000014507.3 UniProtKB/TrEMBL
  ENSSTOT00000032803.1 UniProtKB/TrEMBL
Gene3D-CATH 2.40.50.1070 UniProtKB/TrEMBL
  3.30.70.330 UniProtKB/TrEMBL
  3.40.50.150 UniProtKB/TrEMBL
InterPro Methyltransf_25 UniProtKB/TrEMBL
  Nucleotide-bd_a/b_plait_sf UniProtKB/TrEMBL
  RBD_domain_sf UniProtKB/TrEMBL
  RRM_dom UniProtKB/TrEMBL
  SAM-dependent_MTases UniProtKB/TrEMBL
  TRM2_euk UniProtKB/TrEMBL
  TRMT2A_RRM UniProtKB/TrEMBL
  U5_MeTrfase_fam UniProtKB/TrEMBL
NCBI Gene Trmt2a ENTREZGENE
PANTHER PTHR45904 UniProtKB/TrEMBL
  TRNA (URACIL-5-)-METHYLTRANSFERASE HOMOLOG A UniProtKB/TrEMBL
Pfam Methyltransf_25 UniProtKB/TrEMBL
  tRNA_U5-meth_tr UniProtKB/TrEMBL
PROSITE RRM UniProtKB/TrEMBL
  SAM_MT_RNA_M5U UniProtKB/TrEMBL
Superfamily-SCOP SSF53335 UniProtKB/TrEMBL
  SSF54928 UniProtKB/TrEMBL
UniProt A0A287DE56_ICTTR UniProtKB/TrEMBL
  I3MN24_ICTTR UniProtKB/TrEMBL