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Gene: HMGB3 (high mobility group box 3) Canis lupus familiaris

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Symbol:

HMGB3

Name:

high mobility group box 3

RGD ID:

12426825

Description:

ENCODES a protein that exhibits DNA binding (inferred); DNA binding, bending (inferred); RNA binding (inferred); INVOLVED IN negative regulation of B cell differentiation (ortholog); negative regulation of myeloid cell differentiation (ortholog); ASSOCIATED WITH autistic disorder (ortholog); autosomal hemophilia A (ortholog); centronuclear myopathy X-linked (ortholog); FOUND IN chromosome (inferred); nucleus (inferred); INTERACTS WITH bisphenol A

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

high mobility group protein B3

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	HMGB3 (high mobility group box 3)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Treefam
Mus musculus (house mouse):	Hmgb3 (high mobility group box 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Hmgb3 (high mobility group box 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Hmgb3 (high mobility group box 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	HMGB3 (high mobility group box 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Hmgb3 (high mobility group box 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	HMGB3 (high mobility group box 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	HMGB3 (high mobility group box 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Hmgb3 (high mobility group box 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	X	119,152,166 - 119,159,803 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	X	119,155,786 - 119,159,814 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	X	104,533,386 - 104,542,947 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	X	121,372,243 - 121,381,804 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	X	121,371,809 - 121,379,334 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	X	118,098,022 - 118,107,582 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	X	120,575,897 - 120,585,346 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	X	120,458,422 - 120,467,983 (+)	NCBI		UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autistic disorder (ISO)

autosomal hemophilia A (ISO)

centronuclear myopathy X-linked (ISO)

factor VIII deficiency (ISO)

syndromic microphthalmia 13 (ISO)

syndromic X-linked intellectual disability Lubs type (ISO)

urinary bladder cancer (ISO)

X-linked myopathy with excessive autophagy (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

bisphenol A (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

DNA metabolic process (IEA)

innate immune response (IEA)

negative regulation of B cell differentiation (IEA,ISO)

negative regulation of myeloid cell differentiation (IEA,ISO)

Cellular Component

chromosome (IEA)

nucleus (IEA)

Molecular Function

DNA binding (IEA)

DNA binding, bending (IEA)

protein binding (ISO)

RNA binding (IEA)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

HMGB3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	X	119,152,166 - 119,159,803 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	X	119,155,786 - 119,159,814 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	X	104,533,386 - 104,542,947 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	X	121,372,243 - 121,381,804 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	X	121,371,809 - 121,379,334 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	X	118,098,022 - 118,107,582 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	X	120,575,897 - 120,585,346 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	X	120,458,422 - 120,467,983 (+)	NCBI		UU_Cfam_GSD_1.0

HMGB3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	X	150,980,507 - 150,990,771 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	X	150,980,509 - 150,990,771 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	X	150,148,980 - 150,159,244 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	X	149,902,421 - 149,909,906 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	X	149,822,336 - 149,827,902	NCBI
Celera	X	150,399,636 - 150,407,102 (+)	NCBI		Celera
Cytogenetic Map	X	q28	NCBI
HuRef	X	139,013,654 - 139,018,732 (+)	NCBI		HuRef
CHM1_1	X	150,026,145 - 150,033,552 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	X	149,248,003 - 149,258,240 (+)	NCBI		T2T-CHM13v2.0

Hmgb3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	X	70,599,523 - 70,604,261 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	X	70,599,524 - 70,604,282 (+)	Ensembl		GRCm39 Ensembl
GRCm38	X	71,555,917 - 71,560,673 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	X	71,555,918 - 71,560,676 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	X	68,809,168 - 68,813,829 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	X	67,816,549 - 67,821,210 (+)	NCBI		MGSCv36	mm8
Celera	X	62,536,255 - 62,540,916 (+)	NCBI		Celera
Cytogenetic Map	X	A7.3	NCBI
cM Map	X	36.92	NCBI

Hmgb3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	X	154,341,106 - 154,346,087 (+)	NCBI		GRCr8
mRatBN7.2	X	149,296,303 - 149,301,290 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	X	149,296,375 - 149,301,292 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	X	151,490,519 - 151,495,501 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	X	155,024,716 - 155,029,697 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	X	152,566,272 - 152,571,254 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	17	36,690,190 - 36,694,329 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	17	36,690,249 - 36,694,325 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0 Ensembl	14	51,458,443 - 51,462,721 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	14	51,617,771 - 51,622,052 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	X	157,027,845 - 157,033,080 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	14	48,405,656 - 48,406,577 (-)	NCBI		Celera
Cytogenetic Map	X	q37	NCBI

Hmgb3
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955498	6,633,336 - 6,640,459 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955498	6,633,540 - 6,640,393 (+)	NCBI	ChiLan1.0	ChiLan1.0

HMGB3
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	X	151,119,492 - 151,127,518 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	X	151,123,503 - 151,131,123 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	X	140,632,163 - 140,639,774 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	X	150,565,153 - 150,570,752 (+)	NCBI	panpan1.1	PanPan1.1	panPan2

Hmgb3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	X	116,726,610 - 116,736,044 (+)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936714	1,523,016 - 1,527,301 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

HMGB3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	X	122,592,936 - 122,599,493 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	X	122,591,413 - 122,599,496 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	X	140,189,835 - 140,193,015 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

HMGB3
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	X	125,568,622 - 125,572,184 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666065	63,317,615 - 63,325,146 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Hmgb3
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624923	1,245,898 - 1,250,571 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in HMGB3
51 total Variants

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

adipose tissue	alimentary part of gastrointestinal system	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	reproductive system	respiratory system
6	5	5	23	22	16	6	6	6	6	33	22	12	14	10

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_038451124	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038451125	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038451126	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038464873	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038464874	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038524592	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038524593	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038524594	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038588559	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038588560	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038588561	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038653063	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038653064	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038653065	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_538194	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000146	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000405	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000110	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000175	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000039	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCAFT00000045229 ⟹ ENSCAFP00000037265

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	X	119,155,786 - 119,159,814 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00845043398 ⟹ ENSCAFP00845034000

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	X	121,371,809 - 121,379,334 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00845043452 ⟹ ENSCAFP00845034042

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	X	121,374,667 - 121,379,334 (+)	Ensembl

RefSeq Acc Id:

XM_038451124 ⟹ XP_038307052

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	X	121,372,243 - 121,381,804 (+)	NCBI

RefSeq Acc Id:

XM_038451125 ⟹ XP_038307053

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	X	121,374,769 - 121,381,804 (+)	NCBI

RefSeq Acc Id:

XM_038451126 ⟹ XP_038307054

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	X	121,375,056 - 121,381,804 (+)	NCBI

RefSeq Acc Id:

XM_038464873 ⟹ XP_038320801

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
Dog10K_Boxer_Tasha	X	104,535,912 - 104,542,947 (+)	NCBI

RefSeq Acc Id:

XM_038464874 ⟹ XP_038320802

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
Dog10K_Boxer_Tasha	X	104,536,199 - 104,542,947 (+)	NCBI

RefSeq Acc Id:

XM_038524592 ⟹ XP_038380520

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	X	118,098,022 - 118,107,582 (+)	NCBI

RefSeq Acc Id:

XM_038524593 ⟹ XP_038380521

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	X	118,100,548 - 118,107,582 (+)	NCBI

RefSeq Acc Id:

XM_038524594 ⟹ XP_038380522

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	X	118,100,835 - 118,107,582 (+)	NCBI

RefSeq Acc Id:

XM_038588559 ⟹ XP_038444487

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	X	120,458,422 - 120,467,983 (+)	NCBI

RefSeq Acc Id:

XM_038588560 ⟹ XP_038444488

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	X	120,460,948 - 120,467,983 (+)	NCBI

RefSeq Acc Id:

XM_038588561 ⟹ XP_038444489

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	X	120,461,235 - 120,467,983 (+)	NCBI

RefSeq Acc Id:

XM_038653063 ⟹ XP_038508991

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	X	120,575,897 - 120,585,346 (+)	NCBI

RefSeq Acc Id:

XM_038653064 ⟹ XP_038508992

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	X	120,578,423 - 120,585,346 (+)	NCBI

RefSeq Acc Id:

XM_038653065 ⟹ XP_038508993

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	X	120,578,710 - 120,585,346 (+)	NCBI

RefSeq Acc Id:

XM_538194 ⟹ XP_538194

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	X	119,152,166 - 119,159,803 (+)	NCBI
Dog10K_Boxer_Tasha	X	104,533,386 - 104,542,947 (+)	NCBI

Sequence:

show sequence

ACAAGTGCTTCAGCTTCATAGAAGGAGGAGCTTTCGAGGGAGCTGGATAGGAGGAGCTTTCGAG
GGAGCTGGATAGAAGGAGGAGCTTTCTCGGGAGCGGAGATGGAAACTCTTCCTTTGAAGAATCC
GAGGAAGCCTTTTGTCATTCGAATCAGGATGGCTAAAGGTGATCCCAAGAAACCAAAGGGCAAG
ATGTCTGCTTATGCCTTCTTTGTGCAGACGTGCAGAGAGGAACATAAGAAGAAAAACCCGGAGG
TTCCTGTCAATTTTGCTGAGTTTTCCAAGAAGTGCTCTGAGAGGTGGAAGACAATGTCTGGAAA
AGAGAAGTCGAAATTTGATGAAATGGCCAAGGCAGATAAAGTGCGCTATGATCGGGAAATGAAG
GATTATGGACCCGCTAAGGGAGGCAAGAAGAAGAAGGACCCTAATGCCCCCAAAAGACCACCGT
CTGGATTTTTCCTGTTCTGCTCGGAATTCCGCCCCAAGATCAAATCGACAAACCCTGGAATCTC
CATTGGAGATGTGGCGAAGAAGCTCGGTGAGATGTGGAATAACTTAAGTGACAGCGAGAAGCAG
CCTTACAACAACAAGGCAGCCAAGCTGAAGGAGAAGTATGAGAAGGATGTCGCTGACTATAAGT
CTAAAGGGAAGTTTGATGGCGCAAAGGGTCCCGCTAAAGTTGCCCGGAAAAAGGTGGAAGAAGA
AGATGAAGAAGACGAAGAGGAAGAAGAGGAGGAGGAGGAGGAGGAGGAGGATGAATAAAAAAAC
TGTTGATCTGTCTCCTTGTGAATACCTTAGAGTAGGGAGCGCCGTCATTGACACCTCTCTTATT
CGAGGCGTGTCTGTTGCCCTCGTTAGGTTTAATTACACAATTGGGTCATGGTCATATTGTAGTT
TCTCAAAGTGCTCTAGAAATCGTCAGTGGTTTACATGAAGTGGCCATGGGTGTCCGGAGCACCC
TGAAACTGTATCAAAGTTGTACATATTTCCAAAACATTTTTAAAAATGAAAAGGCTCTCGTGTT
CTCCTCACTCTGTGCACTTTGCTGTTGGTGTGACAAGGCATTTAAAGATGTTTCTGGCATTTTT
TTCTTTTTTTTTTTTTAATTTGTAAGGTGGTGTTAAACTATATGGTTATTGGCTAGAAATCCTG
AGTTATCAACTGTACATATCTATAGTTTGTAAAAAAAAAAAAAAAAAAAGAGAGAGAGAGAGAG
AGAACAAAACAACCGAGACAAACTCTTGATGCTCCTTGCTTGGCGTTGAGGCTGTGGGGAAGAT
GCCTTTGGGAGGGGCTGTAGCTCAGGGCGTGCACTGTGAGGCTGGACCTGTGGACACTGCAGTG
GGCATCCATTTAGCTTCAGGTTGTCTTGTTTCTGTATATAGTGACCTAGCATTCTGCTGCCATT
CTTAGCTGTGGAAAAGGGGGGGTCAGCTGGCATGAGAAGTGTTTGGATCCTTTTTAGTTAAGTG
CGGTAGTTTTAAACTGTTTGTTTTTAAACAAACTGTAGAACTCTTCATTGTCAGCAAAGCGAAG
AGCCACTGCATCAATGAAAGTTCAAGAACCTTCTGTACTAAACACGACTTGCAACGTTCTGTTA
TTTTTTTTGTATGTTTAGAATGCTGAAATGTTTTTGAAGTTAAATAAACAGTATTACATTTTTA
AAA

hide sequence

Protein Sequences


Protein RefSeqs	XP_038307052	(Get FASTA)	NCBI Sequence Viewer
	XP_038307053	(Get FASTA)	NCBI Sequence Viewer
	XP_038307054	(Get FASTA)	NCBI Sequence Viewer
	XP_038320801	(Get FASTA)	NCBI Sequence Viewer
	XP_038320802	(Get FASTA)	NCBI Sequence Viewer
	XP_038380520	(Get FASTA)	NCBI Sequence Viewer
	XP_038380521	(Get FASTA)	NCBI Sequence Viewer
	XP_038380522	(Get FASTA)	NCBI Sequence Viewer
	XP_038444487	(Get FASTA)	NCBI Sequence Viewer
	XP_038444488	(Get FASTA)	NCBI Sequence Viewer
	XP_038444489	(Get FASTA)	NCBI Sequence Viewer
	XP_038508991	(Get FASTA)	NCBI Sequence Viewer
	XP_038508992	(Get FASTA)	NCBI Sequence Viewer
	XP_038508993	(Get FASTA)	NCBI Sequence Viewer
	XP_538194	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000037265.3
	ENSCAFP00000072765.1
	ENSCAFP00040026986.1
	ENSCAFP00040027014.1
	ENSCAFP00040027058.1
	ENSCAFP00845034000
	ENSCAFP00845034000.1
	ENSCAFP00845034042.1

RefSeq Acc Id:	XP_538194 ⟸ XM_538194
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C0SUV1 (UniProtKB/TrEMBL), A0A8I3PS14 (UniProtKB/TrEMBL)
- Sequence:	show sequence METLPLKNPRKPFVIRIRMAKGDPKKPKGKMSAYAFFVQTCREEHKKKNPEVPVNFAEFSKKCS ERWKTMSGKEKSKFDEMAKADKVRYDREMKDYGPAKGGKKKKDPNAPKRPPSGFFLFCSEFRPK IKSTNPGISIGDVAKKLGEMWNNLSDSEKQPYNNKAAKLKEKYEKDVADYKSKGKFDGAKGPAK VARKKVEEEDEEDEEEEEEEEEEEEDE hide sequence

Ensembl Acc Id:

ENSCAFP00000037265 ⟸ ENSCAFT00000045229

RefSeq Acc Id:	XP_038380520 ⟸ XM_038524592
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038380521 ⟸ XM_038524593
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038380522 ⟸ XM_038524594
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038508991 ⟸ XM_038653063
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038508992 ⟸ XM_038653064
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038508993 ⟸ XM_038653065
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038307052 ⟸ XM_038451124
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C0SUV1 (UniProtKB/TrEMBL), A0A8I3PS14 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038307053 ⟸ XM_038451125
- Peptide Label:	isoform X2
- UniProtKB:	A0A8C0R6H3 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038307054 ⟸ XM_038451126
- Peptide Label:	isoform X2
- UniProtKB:	A0A8C0R6H3 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038320801 ⟸ XM_038464873
- Peptide Label:	isoform X2
- UniProtKB:	A0A8C0R6H3 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038320802 ⟸ XM_038464874
- Peptide Label:	isoform X2
- UniProtKB:	A0A8C0R6H3 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038444487 ⟸ XM_038588559
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C0SUV1 (UniProtKB/TrEMBL), A0A8I3PS14 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038444488 ⟸ XM_038588560
- Peptide Label:	isoform X2
- UniProtKB:	A0A8C0R6H3 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038444489 ⟸ XM_038588561
- Peptide Label:	isoform X2
- UniProtKB:	A0A8C0R6H3 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSCAFP00845034000 ⟸ ENSCAFT00845043398

Ensembl Acc Id:

ENSCAFP00845034042 ⟸ ENSCAFT00845043452

Protein Domains

HMG box

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000028715	Ensembl, UniProtKB/TrEMBL
	ENSCAFG00040016824	UniProtKB/TrEMBL
	ENSCAFG00845024577	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000045229.3	UniProtKB/TrEMBL
	ENSCAFT00000106856.1	UniProtKB/TrEMBL
	ENSCAFT00040031046.1	UniProtKB/TrEMBL
	ENSCAFT00040031074.1	UniProtKB/TrEMBL
	ENSCAFT00040031122.1	UniProtKB/TrEMBL
	ENSCAFT00845043398	ENTREZGENE
	ENSCAFT00845043398.1	UniProtKB/TrEMBL
	ENSCAFT00845043452.1	UniProtKB/TrEMBL
Gene3D-CATH	1.10.30.10	UniProtKB/TrEMBL
InterPro	HMG_box_dom	UniProtKB/TrEMBL
	HMG_box_dom_sf	UniProtKB/TrEMBL
	HMG_boxA_CS	UniProtKB/TrEMBL
	HMGB	UniProtKB/TrEMBL
NCBI Gene	HMGB3	ENTREZGENE
PANTHER	HIGH MOBILITY GROUP PROTEIN B3	UniProtKB/TrEMBL
	HIGH MOBILITY GROUP PROTEIN DSP1	UniProtKB/TrEMBL
Pfam	HMG_box	UniProtKB/TrEMBL
	HMG_box_2	UniProtKB/TrEMBL
PRINTS	HIGHMOBLTY12	UniProtKB/TrEMBL
PROSITE	HMG_BOX_1	UniProtKB/TrEMBL
	HMG_BOX_2	UniProtKB/TrEMBL
SMART	HMG	UniProtKB/TrEMBL
Superfamily-SCOP	SSF47095	UniProtKB/TrEMBL
UniProt	A0A8C0R6H3	ENTREZGENE
	A0A8C0SUA2_CANLF	UniProtKB/TrEMBL
	A0A8C0SUV1	ENTREZGENE, UniProtKB/TrEMBL
	A0A8C0SVF8_CANLF	UniProtKB/TrEMBL
	A0A8I3PS14	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3Q3D5_CANLF	UniProtKB/TrEMBL
	A0A8P0NP69_CANLF	UniProtKB/TrEMBL
VGNC ID	VGNC:54164	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - OMIM

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