CCK (cholecystokinin) - Rat Genome Database

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Gene: CCK (cholecystokinin) Canis lupus familiaris
Analyze
Symbol: CCK
Name: cholecystokinin
RGD ID: 12425793
Description: ENCODES a protein that exhibits hormone activity (ortholog); neuropeptide hormone activity (ortholog); receptor ligand activity (ortholog); INVOLVED IN apoptotic DNA fragmentation (ortholog); axonogenesis (ortholog); cholecystokinin signaling pathway (ortholog); ASSOCIATED WITH acute pancreatitis (ortholog); alcohol dependence (ortholog); Alcohol Withdrawal Delirium (ortholog); FOUND IN axon (ortholog); axon hillock (ortholog); axon initial segment (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Cholecystokinins
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12311,414,254 - 11,419,990 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2311,414,249 - 11,454,198 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2311,451,726 - 11,457,488 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02311,701,990 - 11,707,749 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2311,701,991 - 11,707,673 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12311,504,111 - 11,509,872 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02311,646,349 - 11,652,103 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02311,650,493 - 11,656,260 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:25192892   PMID:30032202  


Genomics

Comparative Map Data
CCK
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12311,414,254 - 11,419,990 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2311,414,249 - 11,454,198 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2311,451,726 - 11,457,488 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02311,701,990 - 11,707,749 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2311,701,991 - 11,707,673 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12311,504,111 - 11,509,872 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02311,646,349 - 11,652,103 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02311,650,493 - 11,656,260 (-)NCBIUU_Cfam_GSD_1.0
CCK
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38342,257,826 - 42,266,185 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl342,257,825 - 42,266,185 (-)EnsemblGRCh38hg38GRCh38
GRCh37342,299,318 - 42,307,677 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36342,274,322 - 42,281,399 (-)NCBINCBI36Build 36hg18NCBI36
Build 34342,274,321 - 42,281,399NCBI
Celera342,238,692 - 42,247,029 (-)NCBICelera
Cytogenetic Map3p22.1NCBI
HuRef342,342,652 - 42,351,001 (-)NCBIHuRef
CHM1_1342,250,425 - 42,258,774 (-)NCBICHM1_1
T2T-CHM13v2.0342,275,821 - 42,284,183 (-)NCBIT2T-CHM13v2.0
Cck
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399121,318,890 - 121,324,728 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl9121,318,890 - 121,324,760 (-)EnsemblGRCm39 Ensembl
GRCm389121,489,824 - 121,495,694 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9121,489,824 - 121,495,694 (-)EnsemblGRCm38mm10GRCm38
MGSCv379121,398,942 - 121,404,807 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv369121,338,523 - 121,344,360 (-)NCBIMGSCv36mm8
Celera9121,960,523 - 121,966,357 (-)NCBICelera
Cytogenetic Map9F4NCBI
cM Map972.43NCBI
Cck
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88130,031,012 - 130,037,702 (-)NCBIGRCr8
mRatBN7.28121,153,499 - 121,160,194 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8121,153,500 - 121,160,084 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx8126,751,677 - 126,758,281 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08124,950,740 - 124,957,344 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08122,780,342 - 122,786,944 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.08130,120,525 - 130,127,515 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8130,120,523 - 130,127,392 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08129,312,785 - 129,319,582 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48126,492,636 - 126,499,220 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.18126,512,372 - 126,518,954 (-)NCBI
Celera8120,288,523 - 120,295,093 (-)NCBICelera
RH 3.4 Map81254.7RGD
RH 3.4 Map81282.1RGD
Cytogenetic Map8q32NCBI
Cck
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542028,438,806 - 28,443,458 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542028,438,806 - 28,443,458 (+)NCBIChiLan1.0ChiLan1.0
CCK
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2242,225,061 - 42,233,431 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1342,229,822 - 42,238,192 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0342,168,012 - 42,176,358 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1342,431,021 - 42,439,396 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl342,431,022 - 42,439,396 (-)Ensemblpanpan1.1panPan2
Cck
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118200,424,409 - 200,429,945 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366952,776,831 - 2,782,061 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366952,776,705 - 2,782,280 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CCK
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1325,937,645 - 25,945,793 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11325,940,674 - 25,945,879 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21328,610,211 - 28,615,371 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CCK
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1223,698,192 - 3,705,443 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl223,698,173 - 3,704,956 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041163,500,609 - 163,507,518 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cck
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473077,309,633 - 77,314,384 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473077,310,080 - 77,314,258 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in CCK
89 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
5 5 5 23 18 12 2 6 2 6 29 22 12 14 10

Sequence


Ensembl Acc Id: ENSCAFT00000008465   ⟹   ENSCAFP00000007846
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2311,414,249 - 11,419,932 (-)Ensembl
Ensembl Acc Id: ENSCAFT00000085137   ⟹   ENSCAFP00000065716
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2311,414,249 - 11,454,198 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845033932   ⟹   ENSCAFP00845026553
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2311,701,991 - 11,707,673 (-)Ensembl
RefSeq Acc Id: XM_038432004   ⟹   XP_038287932
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02311,701,990 - 11,707,749 (-)NCBI
RefSeq Acc Id: XM_038507314   ⟹   XP_038363242
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12311,504,111 - 11,509,872 (-)NCBI
RefSeq Acc Id: XM_038570550   ⟹   XP_038426478
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02311,650,493 - 11,656,260 (-)NCBI
RefSeq Acc Id: XM_038634729   ⟹   XP_038490657
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02311,646,349 - 11,652,103 (-)NCBI
RefSeq Acc Id: XM_846822   ⟹   XP_851915
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12311,414,254 - 11,419,990 (-)NCBI
Dog10K_Boxer_Tasha2311,451,726 - 11,457,488 (-)NCBI
Sequence:
RefSeq Acc Id: XP_851915   ⟸   XM_846822
- UniProtKB: A0A8C0NBZ7 (UniProtKB/TrEMBL),   A0A8C0R7P5 (UniProtKB/TrEMBL),   A0A8I3S0Y6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCAFP00000007846   ⟸   ENSCAFT00000008465
Ensembl Acc Id: ENSCAFP00000065716   ⟸   ENSCAFT00000085137
RefSeq Acc Id: XP_038363242   ⟸   XM_038507314
RefSeq Acc Id: XP_038490657   ⟸   XM_038634729
RefSeq Acc Id: XP_038287932   ⟸   XM_038432004
- UniProtKB: A0A8C0NBZ7 (UniProtKB/TrEMBL),   A0A8C0R7P5 (UniProtKB/TrEMBL),   A0A8I3S0Y6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038426478   ⟸   XM_038570550
- UniProtKB: A0A8C0NBZ7 (UniProtKB/TrEMBL),   A0A8C0R7P5 (UniProtKB/TrEMBL),   A0A8I3S0Y6 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCAFP00845026553   ⟸   ENSCAFT00845033932
Protein Domains
Gastrin/cholecystokinin peptide hormone


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000005246 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030015205 UniProtKB/TrEMBL
  ENSCAFG00040021955 UniProtKB/TrEMBL
  ENSCAFG00845019239 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000008465.5 UniProtKB/TrEMBL
  ENSCAFT00030028069.1 UniProtKB/TrEMBL
  ENSCAFT00030028105.1 UniProtKB/TrEMBL
  ENSCAFT00040040766.1 UniProtKB/TrEMBL
  ENSCAFT00040040797.1 UniProtKB/TrEMBL
  ENSCAFT00845033932 ENTREZGENE
  ENSCAFT00845033932.1 UniProtKB/TrEMBL
InterPro CCK-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Gastrin/CCK UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Gastrin/cholecystokinin_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report cfa:609547 UniProtKB/TrEMBL
NCBI Gene CCK ENTREZGENE
PANTHER CHOLECYSTOKININ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR10786 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Gastrin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE GASTRIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART GASTRIN UniProtKB/TrEMBL
UniProt A0A8C0NBZ7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0NM69_CANLF UniProtKB/TrEMBL
  A0A8C0R7P5 ENTREZGENE
  A0A8I3S0Y6 ENTREZGENE, UniProtKB/TrEMBL
  CCKN_CANLF UniProtKB/Swiss-Prot, ENTREZGENE
VGNC ID VGNC:52865 ENTREZGENE