NR4A1 (nuclear receptor subfamily 4 group A member 1) - Rat Genome Database

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Gene: NR4A1 (nuclear receptor subfamily 4 group A member 1) Canis lupus familiaris
Analyze
Symbol: NR4A1
Name: nuclear receptor subfamily 4 group A member 1
RGD ID: 12352582
Description: ENCODES a protein that exhibits DNA binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); identical protein binding (ortholog); INVOLVED IN apoptotic process (ortholog); cell migration involved in sprouting angiogenesis (ortholog); cellular response to corticotropin-releasing hormone stimulus (ortholog); ASSOCIATED WITH Albuminuria (ortholog); blood pressure trait (ortholog); blood urea nitrogen amount (ortholog); FOUND IN cytosol (ortholog); nuclear membrane (ortholog); nucleoplasm (ortholog)
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: NGFI-B; orphan nuclear receptor HMR; orphan nuclear receptor NGFI-B
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1272,947,729 - 2,965,045 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl272,891,053 - 2,955,655 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2743,300,499 - 43,308,433 (+)NCBI
ROS_Cfam_1.0272,944,790 - 2,966,939 (-)NCBI
UMICH_Zoey_3.1272,961,332 - 2,969,256 (-)NCBI
UNSW_CanFamBas_1.0272,947,820 - 2,955,733 (-)NCBI
UU_Cfam_GSD_1.02743,698,715 - 43,706,655 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component


References
Additional References at PubMed
PMID:8895335  


Genomics

Comparative Map Data
NR4A1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1272,947,729 - 2,965,045 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl272,891,053 - 2,955,655 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2743,300,499 - 43,308,433 (+)NCBI
ROS_Cfam_1.0272,944,790 - 2,966,939 (-)NCBI
UMICH_Zoey_3.1272,961,332 - 2,969,256 (-)NCBI
UNSW_CanFamBas_1.0272,947,820 - 2,955,733 (-)NCBI
UU_Cfam_GSD_1.02743,698,715 - 43,706,655 (+)NCBI
NR4A1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1252,022,832 - 52,059,507 (+)EnsemblGRCh38hg38GRCh38
GRCh381252,022,832 - 52,059,507 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371252,416,616 - 52,453,287 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361250,731,458 - 50,739,554 (+)NCBINCBI36hg18NCBI36
Build 341250,723,762 - 50,736,019NCBI
Celera1251,247,867 - 51,255,961 (+)NCBI
Cytogenetic Map12q13.13NCBI
HuRef1249,449,770 - 49,486,519 (+)NCBIHuRef
CHM1_11252,382,884 - 52,419,560 (+)NCBICHM1_1
Nr4a1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3915101,151,788 - 101,172,676 (+)NCBIGRCm39mm39
GRCm39 Ensembl15101,152,150 - 101,172,676 (+)Ensembl
GRCm3815101,253,902 - 101,274,795 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl15101,254,269 - 101,274,795 (+)EnsemblGRCm38mm10GRCm38
MGSCv3715101,097,277 - 101,105,226 (+)NCBIGRCm37mm9NCBIm37
MGSCv3615101,094,896 - 101,102,826 (+)NCBImm8
Celera15103,414,983 - 103,422,853 (+)NCBICelera
Cytogenetic Map15F1NCBI
Nr4a1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.27132,368,399 - 132,389,300 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl7132,374,840 - 132,389,297 (+)Ensembl
Rnor_6.07142,899,358 - 142,920,216 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7142,905,758 - 142,920,216 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07140,700,242 - 140,721,073 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47140,012,807 - 140,020,590 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.17140,089,243 - 140,097,024 (+)NCBI
Celera7128,846,928 - 128,854,640 (+)NCBICelera
Cytogenetic Map7q36NCBI
Nr4a1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555472,404,532 - 2,431,050 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555472,404,532 - 2,426,882 (+)NCBIChiLan1.0ChiLan1.0
NR4A1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11237,480,300 - 37,498,290 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1237,480,300 - 37,501,188 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01236,703,903 - 36,740,211 (-)NCBIMhudiblu_PPA_v0panPan3
Nr4a1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494563,656,496 - 63,678,740 (-)NCBI
SpeTri2.0NW_0049365129,486,096 - 9,508,338 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NR4A1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11148,208,354 - 48,232,857 (+)NCBI
ChlSab1.1 Ensembl1148,208,587 - 48,233,063 (+)Ensembl
Vero_WHO_p1.0NW_023666037197,859,302 - 197,884,070 (-)NCBI
Nr4a1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624816271,345 - 288,265 (-)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 4 5 16 2 6 2 2 3 12 8 1
Low 1 6 4 4 4 3 8 2 5
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001003227 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005636676 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_014108245 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_014108246 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022410843 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038437739 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038437740 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038437742 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038437743 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038437744 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000027 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000296 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000069 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000362 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000027 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X97226 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCAFT00000011743   ⟹   ENSCAFP00000010883
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl272,947,732 - 2,955,655 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000064912   ⟹   ENSCAFP00000062914
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl272,947,732 - 2,955,049 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000068891   ⟹   ENSCAFP00000063260
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl272,913,590 - 2,955,655 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000074053   ⟹   ENSCAFP00000066436
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl272,947,732 - 2,955,655 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000077886   ⟹   ENSCAFP00000066519
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl272,938,824 - 2,955,655 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000091020   ⟹   ENSCAFP00000048033
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl272,891,053 - 2,955,655 (-)Ensembl
RefSeq Acc Id: NM_001003227   ⟹   NP_001003227
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1272,947,729 - 2,955,655 (-)NCBI
Dog10K_Boxer_Tasha2743,300,499 - 43,308,433 (+)NCBI
ROS_Cfam_1.0272,944,790 - 2,952,739 (-)NCBI
UMICH_Zoey_3.1272,961,332 - 2,969,256 (-)NCBI
UNSW_CanFamBas_1.0272,947,820 - 2,955,733 (-)NCBI
UU_Cfam_GSD_1.02743,698,715 - 43,706,655 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005636676   ⟹   XP_005636733
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1272,947,729 - 2,965,045 (-)NCBI
Sequence:
RefSeq Acc Id: XM_014108245   ⟹   XP_013963720
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1272,947,729 - 2,962,949 (-)NCBI
Sequence:
RefSeq Acc Id: XM_014108246   ⟹   XP_013963721
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1272,947,729 - 2,965,031 (-)NCBI
Sequence:
RefSeq Acc Id: XM_022410843   ⟹   XP_022266551
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1272,947,729 - 2,964,033 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038437739   ⟹   XP_038293667
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0272,944,790 - 2,962,174 (-)NCBI
RefSeq Acc Id: XM_038437740   ⟹   XP_038293668
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0272,944,790 - 2,966,939 (-)NCBI
RefSeq Acc Id: XM_038437742   ⟹   XP_038293670
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0272,944,790 - 2,960,018 (-)NCBI
RefSeq Acc Id: XM_038437743   ⟹   XP_038293671
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0272,944,790 - 2,961,149 (-)NCBI
RefSeq Acc Id: XM_038437744   ⟹   XP_038293672
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0272,944,790 - 2,962,174 (-)NCBI
Reference Sequences
RefSeq Acc Id: XP_013963721   ⟸   XM_014108246
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_005636733   ⟸   XM_005636676
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_013963720   ⟸   XM_014108245
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: NP_001003227   ⟸   NM_001003227
- UniProtKB: P51666 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_022266551   ⟸   XM_022410843
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSCAFP00000063260   ⟸   ENSCAFT00000068891
RefSeq Acc Id: ENSCAFP00000066436   ⟸   ENSCAFT00000074053
RefSeq Acc Id: ENSCAFP00000062914   ⟸   ENSCAFT00000064912
RefSeq Acc Id: ENSCAFP00000010883   ⟸   ENSCAFT00000011743
RefSeq Acc Id: ENSCAFP00000066519   ⟸   ENSCAFT00000077886
RefSeq Acc Id: ENSCAFP00000048033   ⟸   ENSCAFT00000091020
RefSeq Acc Id: XP_038293668   ⟸   XM_038437740
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038293672   ⟸   XM_038437744
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038293667   ⟸   XM_038437739
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038293671   ⟸   XM_038437743
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038293670   ⟸   XM_038437742
- Peptide Label: isoform X1

Promoters
RGD ID:13688097
Promoter ID:EPDNEW_C6165
Type:multiple initiation site
Name:NR4A1_1
Description:nuclear receptor subfamily 4 group A member 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1272,955,679 - 2,955,739EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000007338 Ensembl, ENTREZGENE
Ensembl Protein ENSCAFP00000010883 ENTREZGENE
Ensembl Transcript ENSCAFT00000011743 ENTREZGENE
NCBI Gene NR4A1 ENTREZGENE
UniProt P51666 ENTREZGENE
VGNC ID VGNC:43954 ENTREZGENE