NR4A1 (nuclear receptor subfamily 4 group A member 1)

	Submit Data \| Help \| Video Tutorials \| News \| Publications \| Download \| REST API \| Citing RGD \| Contact
	Search RGD Grant Resources Citing RGD About Us Contact Us Genes QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) (beta) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer) Overgo Probe Designer Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease COVID-19 Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease Find Models new Genetic Models Autism Models PhenoMiner (Quantitative Phenotypes) Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes GERRC (Gene Editing Rat Resource Center) Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive Pathways Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Poster Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
	Advanced Search (OLGA)

Gene: NR4A1 (nuclear receptor subfamily 4 group A member 1) Canis lupus familiaris

Analyze

Symbol:

NR4A1

Name:

nuclear receptor subfamily 4 group A member 1

RGD ID:

12352582

Description:

ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); protein heterodimerization activity (ortholog); INVOLVED IN apoptotic process (ortholog); cellular response to corticotropin-releasing hormone stimulus (ortholog); cellular response to organic substance (ortholog); ASSOCIATED WITH Albuminuria (ortholog); blood pressure trait (ortholog); blood urea nitrogen amount (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); mitochondrion (inferred)

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

NGFI-B; orphan nuclear receptor HMR; orphan nuclear receptor NGFI-B

RGD Orthologs

Human

Mouse

Rat

Chinchilla

Bonobo

Squirrel

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	27	2,947,729 - 2,965,045 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	27	2,891,053 - 2,955,655 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	27	43,300,499 - 43,308,433 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	27	2,944,790 - 2,966,939 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	27	2,939,797 - 2,965,600 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	27	2,961,332 - 2,969,256 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	27	2,947,820 - 2,955,733 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	27	43,698,715 - 43,706,655 (+)	NCBI		UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Experimental Data Annotations Click to see Annotation Detail View

Vertebrate Trait

Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
blood pressure trait		ISO	RGD:620029	9068941		RGD	PMID:24722447, REF_RGD_ID:12910103
blood urea nitrogen amount		ISO	RGD:620029	9068941		RGD	PMID:24722447, REF_RGD_ID:12910103
cholesterol amount		ISO	RGD:620029	9068941		RGD	PMID:24722447, REF_RGD_ID:12910103
macrophage migration trait		ISO	RGD:620029	9068941		RGD	PMID:24722447, REF_RGD_ID:12910103
triglyceride amount		ISO	RGD:620029	9068941		RGD	PMID:24722447, REF_RGD_ID:12910103

Disease Annotations Click to see Annotation Detail View

Albuminuria (ISO)

chronic kidney disease (ISO)

Dyskinesias (ISO)

endometriosis (ISO)

genetic disease (ISO)

Hypercholesterolemia (ISO)

Hypertriglyceridemia (ISO)

Insulin Resistance (ISO)

kidney disease (ISO)

Kidney Reperfusion Injury (ISO)

major depressive disorder (ISO)

mesangial proliferative glomerulonephritis (ISO)

Myocardial Ischemia (ISO)

pancreatic cancer (ISO)

Parkinson's disease (ISO)

proteinuria (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

apoptotic process (IEA,ISO)

cell migration involved in sprouting angiogenesis (IEA)

cellular response to corticotropin-releasing hormone stimulus (IBA,IEA,ISS)

cellular response to fibroblast growth factor stimulus (IEA)

cellular response to organic substance (IEA,ISO)

cellular response to vascular endothelial growth factor stimulus (IEA)

DNA-templated transcription (IEA)

endothelial cell chemotaxis (IEA)

fat cell differentiation (IEA,ISS)

intracellular receptor signaling pathway (IEA)

negative regulation of cell cycle (IEA,ISS)

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process (IEA,ISO)

neurotransmitter secretion involved in regulation of skeletal muscle contraction (ISO)

positive regulation of apoptotic process (IEA,ISO)

positive regulation of DNA-templated transcription (IEA,ISO)

positive regulation of endothelial cell proliferation (IEA)

positive regulation of transcription by RNA polymerase II (IEA,ISO,ISS)

regulation of DNA-templated transcription (IEA)

regulation of transcription by RNA polymerase II (IBA,IEA)

regulation of type B pancreatic cell proliferation (ISS)

response to amphetamine (ISO)

response to electrical stimulus (ISO)

response to lipopolysaccharide (ISO)

skeletal muscle cell differentiation (IEA,ISO)

transcription by RNA polymerase II (IEA,ISO)

Cellular Component

cytoplasm (IEA)

cytosol (IEA)

mitochondrion (IEA)

nuclear membrane (IEA)

nucleoplasm (IEA)

nucleus (IBA,IEA)

transcription regulator complex (IBA,IEA)

Molecular Function

DNA binding (IEA)

DNA-binding transcription activator activity, RNA polymerase II-specific (IEA,ISS)

DNA-binding transcription factor activity (IEA)

DNA-binding transcription factor activity, RNA polymerase II-specific (IBA,IEA)

identical protein binding (IEA)

metal ion binding (IEA)

nuclear glucocorticoid receptor binding (IBA)

nuclear receptor activity (IEA)

protein binding (ISO)

protein heterodimerization activity (ISS)

RNA polymerase II cis-regulatory region sequence-specific DNA binding (IBA)

sequence-specific DNA binding (IEA)

sequence-specific double-stranded DNA binding (IEA)

zinc ion binding (IEA)

Experimental Data Annotations Click to see Annotation Detail View

Vertebrate Trait

blood pressure trait (ISO)

blood urea nitrogen amount (ISO)

cholesterol amount (ISO)

macrophage migration trait (ISO)

triglyceride amount (ISO)

References

Additional References at PubMed

PMID:8895335

Genomics

Comparative Map Data

NR4A1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	27	2,947,729 - 2,965,045 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	27	2,891,053 - 2,955,655 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	27	43,300,499 - 43,308,433 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	27	2,944,790 - 2,966,939 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	27	2,939,797 - 2,965,600 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	27	2,961,332 - 2,969,256 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	27	2,947,820 - 2,955,733 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	27	43,698,715 - 43,706,655 (+)	NCBI		UU_Cfam_GSD_1.0

NR4A1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	12	52,022,832 - 52,059,503 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p13 Ensembl	12	52,022,832 - 52,059,507 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	12	52,416,616 - 52,453,287 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	12	50,731,458 - 50,739,554 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	12	50,723,762 - 50,736,019	NCBI
Celera	12	51,247,867 - 51,255,961 (+)	NCBI		Celera
Cytogenetic Map	12	q13.13	NCBI
HuRef	12	49,449,770 - 49,486,519 (+)	NCBI		HuRef
CHM1_1	12	52,382,884 - 52,419,560 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	12	51,986,402 - 52,023,082 (+)	NCBI		T2T-CHM13v2.0

Nr4a1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	15	101,151,783 - 101,172,676 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	15	101,152,150 - 101,172,676 (+)	Ensembl		GRCm39 Ensembl
GRCm38	15	101,253,902 - 101,274,795 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	15	101,254,269 - 101,274,795 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	15	101,097,277 - 101,105,226 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	15	101,094,896 - 101,102,826 (+)	NCBI		MGSCv36	mm8
Celera	15	103,414,983 - 103,422,853 (+)	NCBI		Celera
Cytogenetic Map	15	F1	NCBI

Nr4a1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	7	132,368,399 - 132,389,300 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	132,374,840 - 132,389,297 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	7	134,182,933 - 134,190,833 (+)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	7	136,412,449 - 136,420,349 (+)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	7	136,322,869 - 136,330,773 (+)	NCBI	Rnor_WKY
Rnor_6.0	7	142,899,358 - 142,920,216 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	142,905,758 - 142,920,216 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	7	140,700,242 - 140,721,073 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	7	140,012,807 - 140,020,590 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	7	140,089,243 - 140,097,024 (+)	NCBI
Celera	7	128,846,928 - 128,854,640 (+)	NCBI		Celera
Cytogenetic Map	7	q36	NCBI

Nr4a1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955547	2,404,532 - 2,431,050 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955547	2,404,532 - 2,426,882 (+)	NCBI	ChiLan1.0	ChiLan1.0

NR4A1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1	12	42,133,103 - 42,154,924 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	12	36,703,903 - 36,740,211 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	12	37,480,300 - 37,498,290 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	12	37,480,300 - 37,501,188 (-)	Ensembl	panpan1.1		panPan2

Nr4a1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404945	63,656,496 - 63,678,740 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936512	9,499,754 - 9,508,423 (+)	Ensembl	SpeTri2.0
SpeTri2.0	NW_004936512	9,486,096 - 9,508,338 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

NR4A1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	11	48,208,354 - 48,232,857 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	11	48,208,587 - 48,233,063 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666037	197,859,302 - 197,884,070 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Nr4a1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624816	267,303 - 293,227 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624816	271,345 - 288,265 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in NR4A1
350 total Variants

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	reproductive system	respiratory system	adipose tissue
High
Medium	4	5	16	2	6	2	2	3	12		8	1
Low	1		6	4		4	4	3		8	2	5
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001003227	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_005636676	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_014108245	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_014108246	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_022410843	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038437739	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038437740	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038437742	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038437743	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038437744	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000027	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000296	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000069	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000362	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000027	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	X97226	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSCAFT00000011743 ⟹ ENSCAFP00000010883

RefSeq Status:

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	27	2,947,732 - 2,955,655 (-)	Ensembl

RefSeq Acc Id:

ENSCAFT00000064912 ⟹ ENSCAFP00000062914

RefSeq Status:

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	27	2,947,732 - 2,955,049 (-)	Ensembl

RefSeq Acc Id:

ENSCAFT00000068891 ⟹ ENSCAFP00000063260

RefSeq Status:

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	27	2,913,590 - 2,955,655 (-)	Ensembl

RefSeq Acc Id:

ENSCAFT00000074053 ⟹ ENSCAFP00000066436

RefSeq Status:

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	27	2,947,732 - 2,955,655 (-)	Ensembl

RefSeq Acc Id:

ENSCAFT00000077886 ⟹ ENSCAFP00000066519

RefSeq Status:

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	27	2,938,824 - 2,955,655 (-)	Ensembl

RefSeq Acc Id:

ENSCAFT00000091020 ⟹ ENSCAFP00000048033

RefSeq Status:

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	27	2,891,053 - 2,955,655 (-)	Ensembl

RefSeq Acc Id:

ENSCAFT00845047685 ⟹ ENSCAFP00845037419

RefSeq Status:

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	27	2,939,797 - 2,960,023 (-)	Ensembl

RefSeq Acc Id:

ENSCAFT00845047860 ⟹ ENSCAFP00845037547

RefSeq Status:

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	27	2,944,790 - 2,965,600 (-)	Ensembl

RefSeq Acc Id:

ENSCAFT00845047929 ⟹ ENSCAFP00845037598

RefSeq Status:

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	27	2,944,790 - 2,960,023 (-)	Ensembl

RefSeq Acc Id:

ENSCAFT00845047987 ⟹ ENSCAFP00845037651

RefSeq Status:

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	27	2,944,790 - 2,960,023 (-)	Ensembl

RefSeq Acc Id:

ENSCAFT00845048033 ⟹ ENSCAFP00845037687

RefSeq Status:

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	27	2,944,790 - 2,952,757 (-)	Ensembl

RefSeq Acc Id:

NM_001003227 ⟹ NP_001003227

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	27	2,947,729 - 2,955,655 (-)	NCBI
Dog10K_Boxer_Tasha	27	43,300,499 - 43,308,433 (+)	NCBI
ROS_Cfam_1.0	27	2,944,790 - 2,952,739 (-)	NCBI
UMICH_Zoey_3.1	27	2,961,332 - 2,969,256 (-)	NCBI
UNSW_CanFamBas_1.0	27	2,947,820 - 2,955,733 (-)	NCBI
UU_Cfam_GSD_1.0	27	43,698,715 - 43,706,655 (+)	NCBI

Sequence:

show sequence

GCCCGGAGCGCGCGGCCGGGAGCGCACACGCGGGACGGACGGGCGGGCGGAGCGGAGCCGCCGG
AGATGCCCTGTATCCAAGCCCAATATGGGACACCAGCACCAAGCCCAGGACCCCGAGACCACCT
GGCAAGCGACCCCCTGACCCCCGAGCTCAGCAAGCCCACCATGGACCTGGCCAGCCCTGAGGCA
GCCCCCACCGCCCCCACGGCCCTGCCCAGCTTCAGCACTTTCATGGACGGCTACACGGGGGAGT
TTGACACCTTCCTGTACCAGCTGCCGGGAACGGCCCAGCCATGCTCTTCGGCCTCCTCTTCGGC
CTCCTCCACGTCCTCCTCCTCGGCCACCTCCCCCGCCTCTGCTTCCTTCAAGTTTGAGGACTTC
CAGGTGTACGGCTGCTACCCTGGCCCCCTGAGCGGTCCCCTGGACGAGACCCTGTCCTCCAGCG
GTTCCGACTACTACGGCAGCCCCTGCTCAGCGCCGTCCCCGTCCACGCCCAGCTTCCAGCCACC
CCAGCTCTCTCCCTGGGATGGCTCGTTCGGCCCCTTCTCACCCAGCCAGACGTACGAAGGCCTG
CGGGCATGGACAGAGCAACTGCCCAAGGCTTCTGGGCACCCCCAGCCGCCTGCCTTTTTTTCCT
TCAGCCCCCCTACTGGTCCCAGTCCCAGCCTTGCCCAGAGCCCCTTGAAGCTGTTCCCCTCACA
GGCCACCTGCCAGCTGGGGGAGAGAGAAAGTTATTCCATATCCACGGCTTTCCCGGGCCTGGCG
CCCACTTCTCCACACCTCGACGGCCCAGGGATGCTGGACGCACCGGTGCCTTCGGCCAAGGCCC
GGAGCGGGGCCCCCAGTGGAAGCGAGGGCCGCTGTGCCGTGTGTGGGGACAACGCTTCGTGCCA
GCATTACGGCGTCCGCACCTGCGAGGGCTGTAAGGGCTTCTTCAAGCGCACAGTACAGAAAAAC
GCCAAGTACATCTGCCTGGCTAACAAGGACTGCCCTGTGGACAAGAGGCGGCGAAACCGCTGCC
AGTTCTGTCGCTTCCAGAAGTGCCTGGCCGTAGGCATGGTGAAGGAAGTTGTCCGGACAGACAG
CCTGAAGGGGCGGCGGGGTCGGCTCCCTTCGAAGCCCAAGCAGCCCCCGGACGCCTCCCCTGCC
AACCTCCTCACGTCCCTGGTCAGGGCACACCTGGACTCCGGGCCCAGCACAGCCAAACTGGACT
ACTCCAAGTTCCAGGAGCTGGTACTGCCCCACTTCGGGAAGGAAGATGCCGGGGACGTGCAGCA
GTTCTACGACCTGCTTTCGGGTTCCCTGGAGGTCATCCGCAAGTGGGCCGAGAAGATCCCCGGC
TTTGCCGAGCTGTCCCCGGGTGACCAGGACCTGCTGCTGGAGTCGGCCTTCCTGGAGCTCTTCA
TCCTCCGCCTGGCCTACCGCTCGAAGCCGGCCGAGGGGAAGCTCATCTTCTGCTCGGGCCTGGT
GCTCCACCGGCTGCAGTGCGCCCGCGGCTTTGGCGACTGGATCGACAGCATTCTGGCCTTCTCT
CGGTCCCTGCACGGCCTGGTGGTGGACGTCCCTGCCTTCGCCTGCCTCTCGGCGCTCGTCCTCA
TCACAGACCGGCACGGGCTGCAAGAGCCAAGGCGGGTGGAGGAGCTGCAAAATCGCATCGCCAG
CTGCCTGAAGGAGCACGTCTCGGCCGTGGCGGGCGAACCGCAGCCGGCCAGCTGCCTGTCACGC
CTGCTGGGCAAGCTCCCCGAGCTGCGGACCCTGTGCACCCAGGGCTTGCAACGCATCTTCTACC
TCAAGCTGGAGGACTTGGTGCCCCCTCCGCCCATTGTCGACAAGATCTTTATGGACACACTGCC
CTTCTGACCCCAGCCCAGGAACACGCGTGCGCCGTGAATGCACGCTCCTACACCACCCCACGTG
CCTTTAGCCCATGGCCCACGGACCCTCAGAGCACCCCCAGCCTGGGCTTGAGCCGCAGACCAGC
CGGCCTCCGCCCTTGTACTGGGTGGTTGGCAGGGAGCTCACGCCCTGGGGGAGGGGGATGCATT
CATGGGGGTGACCCCTACTACTTGTCTTAGCCCCCAGCCCAGCCCTGGCCTTCATGTTTTTGTA
AGATAAACCGTTTTTAACACACACCGCCGTGCTGTAAATAAGCCAGATGCTGCTGTAAATATAG
GAAGGAAGAGGCCGAGATGGGAGTGGGGGCTCGGAGGGAGGGGCGGCCCCCACCAGCCCGGGCA
AGCCTCTCCCGCCTCCTTGCACCTGCTCTCTCTTCCCACCCTCTTTCCACATGTACATAACCTT
ACTCTACAAAGAAGACAAATGACAGATTCTGACATTTATATTTGTGTATTTTCCTGGATTTATA
GTATGTGACTTTTCTGATTAATATATTTAATATATTGAATAAAAAATAGGCCTGTAGCTGAAAA
A

hide sequence

RefSeq Acc Id:

XM_038437739 ⟹ XP_038293667

RefSeq Status:

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	27	2,944,790 - 2,962,174 (-)	NCBI

RefSeq Acc Id:

XM_038437740 ⟹ XP_038293668

RefSeq Status:

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	27	2,944,790 - 2,966,939 (-)	NCBI

RefSeq Acc Id:

XM_038437742 ⟹ XP_038293670

RefSeq Status:

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	27	2,944,790 - 2,960,018 (-)	NCBI

RefSeq Acc Id:

XM_038437743 ⟹ XP_038293671

RefSeq Status:

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	27	2,944,790 - 2,961,149 (-)	NCBI

RefSeq Acc Id:

XM_038437744 ⟹ XP_038293672

RefSeq Status:

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	27	2,944,790 - 2,962,174 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001003227	(Get FASTA)	NCBI Sequence Viewer
	XP_038293667	(Get FASTA)	NCBI Sequence Viewer
	XP_038293668	(Get FASTA)	NCBI Sequence Viewer
	XP_038293670	(Get FASTA)	NCBI Sequence Viewer
	XP_038293671	(Get FASTA)	NCBI Sequence Viewer
	XP_038293672	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	CAA65863	(Get FASTA)	NCBI Sequence Viewer
	P51666	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

NP_001003227 ⟸ NM_001003227

- UniProtKB:

P51666 (UniProtKB/Swiss-Prot), A0A8C0JK87 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MPCIQAQYGTPAPSPGPRDHLASDPLTPELSKPTMDLASPEAAPTAPTALPSFSTFMDGYTGEF
DTFLYQLPGTAQPCSSASSSASSTSSSSATSPASASFKFEDFQVYGCYPGPLSGPLDETLSSSG
SDYYGSPCSAPSPSTPSFQPPQLSPWDGSFGPFSPSQTYEGLRAWTEQLPKASGHPQPPAFFSF
SPPTGPSPSLAQSPLKLFPSQATCQLGERESYSISTAFPGLAPTSPHLDGPGMLDAPVPSAKAR
SGAPSGSEGRCAVCGDNASCQHYGVRTCEGCKGFFKRTVQKNAKYICLANKDCPVDKRRRNRCQ
FCRFQKCLAVGMVKEVVRTDSLKGRRGRLPSKPKQPPDASPANLLTSLVRAHLDSGPSTAKLDY
SKFQELVLPHFGKEDAGDVQQFYDLLSGSLEVIRKWAEKIPGFAELSPGDQDLLLESAFLELFI
LRLAYRSKPAEGKLIFCSGLVLHRLQCARGFGDWIDSILAFSRSLHGLVVDVPAFACLSALVLI
TDRHGLQEPRRVEELQNRIASCLKEHVSAVAGEPQPASCLSRLLGKLPELRTLCTQGLQRIFYL
KLEDLVPPPPIVDKIFMDTLPF

hide sequence

RefSeq Acc Id:

ENSCAFP00000063260 ⟸ ENSCAFT00000068891

RefSeq Acc Id:

ENSCAFP00000066436 ⟸ ENSCAFT00000074053

RefSeq Acc Id:

ENSCAFP00000062914 ⟸ ENSCAFT00000064912

RefSeq Acc Id:

ENSCAFP00000010883 ⟸ ENSCAFT00000011743

RefSeq Acc Id:

ENSCAFP00000066519 ⟸ ENSCAFT00000077886

RefSeq Acc Id:

ENSCAFP00000048033 ⟸ ENSCAFT00000091020

RefSeq Acc Id:	XP_038293668 ⟸ XM_038437740
- Peptide Label:	isoform X1
- UniProtKB:	P51666 (UniProtKB/Swiss-Prot), A0A8C0JK87 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038293672 ⟸ XM_038437744
- Peptide Label:	isoform X1
- UniProtKB:	P51666 (UniProtKB/Swiss-Prot), A0A8C0JK87 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038293667 ⟸ XM_038437739
- Peptide Label:	isoform X1
- UniProtKB:	P51666 (UniProtKB/Swiss-Prot), A0A8C0JK87 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038293671 ⟸ XM_038437743
- Peptide Label:	isoform X1
- UniProtKB:	P51666 (UniProtKB/Swiss-Prot), A0A8C0JK87 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038293670 ⟸ XM_038437742
- Peptide Label:	isoform X1
- UniProtKB:	P51666 (UniProtKB/Swiss-Prot), A0A8C0JK87 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSCAFP00845037598 ⟸ ENSCAFT00845047929

RefSeq Acc Id:

ENSCAFP00845037687 ⟸ ENSCAFT00845048033

RefSeq Acc Id:

ENSCAFP00845037547 ⟸ ENSCAFT00845047860

RefSeq Acc Id:

ENSCAFP00845037419 ⟸ ENSCAFT00845047685

RefSeq Acc Id:

ENSCAFP00845037651 ⟸ ENSCAFT00845047987

Protein Domains

NR LBD Nuclear receptor

Promoters

RGD ID:

13688097

Promoter ID:

EPDNEW_C6165

Type:

multiple initiation site

Name:

NR4A1_1

Description:

nuclear receptor subfamily 4 group A member 1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	27	2,955,679 - 2,955,739	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000007338	Ensembl, UniProtKB/TrEMBL
	ENSCAFG00030022628	UniProtKB/TrEMBL
	ENSCAFG00040018608	UniProtKB/TrEMBL
	ENSCAFG00845026982	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein	ENSCAFP00000010883.4	UniProtKB/TrEMBL
	ENSCAFP00000062914.2	UniProtKB/TrEMBL
	ENSCAFP00000063260.2	UniProtKB/TrEMBL
	ENSCAFP00000066436.1	UniProtKB/TrEMBL
	ENSCAFP00000066519.2	UniProtKB/TrEMBL
	ENSCAFP00030036304.1	UniProtKB/TrEMBL
	ENSCAFP00030036334.1	UniProtKB/TrEMBL
	ENSCAFP00040030140.1	UniProtKB/TrEMBL
	ENSCAFP00040030278.1	UniProtKB/TrEMBL
	ENSCAFP00040030358.1	UniProtKB/TrEMBL
	ENSCAFP00845037419.1	UniProtKB/TrEMBL
	ENSCAFP00845037547.1	UniProtKB/TrEMBL
	ENSCAFP00845037598	ENTREZGENE
	ENSCAFP00845037598.1	UniProtKB/Swiss-Prot
	ENSCAFP00845037651.1	UniProtKB/TrEMBL
	ENSCAFP00845037687	ENTREZGENE
	ENSCAFP00845037687.1	UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000011743.4	UniProtKB/TrEMBL
	ENSCAFT00000064912.2	UniProtKB/TrEMBL
	ENSCAFT00000068891.2	UniProtKB/TrEMBL
	ENSCAFT00000074053.2	UniProtKB/TrEMBL
	ENSCAFT00000077886.2	UniProtKB/TrEMBL
	ENSCAFT00030041607.1	UniProtKB/TrEMBL
	ENSCAFT00030041640.1	UniProtKB/TrEMBL
	ENSCAFT00040034616.1	UniProtKB/TrEMBL
	ENSCAFT00040034772.1	UniProtKB/TrEMBL
	ENSCAFT00040034862.1	UniProtKB/TrEMBL
	ENSCAFT00845047685.1	UniProtKB/TrEMBL
	ENSCAFT00845047860.1	UniProtKB/TrEMBL
	ENSCAFT00845047929	ENTREZGENE
	ENSCAFT00845047929.1	UniProtKB/Swiss-Prot
	ENSCAFT00845047987.1	UniProtKB/TrEMBL
	ENSCAFT00845048033	ENTREZGENE
	ENSCAFT00845048033.1	UniProtKB/TrEMBL
Gene3D-CATH	1.10.565.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	3.30.50.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro	NHR-like_dom_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Nuc_orp_HMR_rcpt	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Nuc_orph_rcpt	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Nucl_hrmn_rcpt_lig-bd	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Nuclear_hrmn_rcpt	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Znf_hrmn_rcpt	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Znf_NHR/GATA	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	cfa:403897	UniProtKB/Swiss-Prot
NCBI Gene	NR4A1	ENTREZGENE
PANTHER	NUCLEAR HORMONE RECEPTOR	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	NUCLEAR RECEPTOR SUBFAMILY 4 GROUP A MEMBER 1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	Hormone_recep	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	zf-C4	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS	HMRNUCRECPTR	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	NUCLEARECPTR	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	STRDHORMONER	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	STROIDFINGER	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE	NR_LBD	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	NUCLEAR_REC_DBD_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	NUCLEAR_REC_DBD_2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART	HOLI	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ZnF_C4	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	Glucocorticoid receptor-like (DNA-binding domain)	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SSF48508	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A8C0JK87	ENTREZGENE
	A0A8C0P5G0_CANLF	UniProtKB/TrEMBL
	A0A8C0T1M9_CANLF	UniProtKB/TrEMBL
	A0A8C0T413_CANLF	UniProtKB/TrEMBL
	A0A8C0T646_CANLF	UniProtKB/TrEMBL
	A0A8I3PRN7_CANLF	UniProtKB/TrEMBL
	A0A8I3PZY4_CANLF	UniProtKB/TrEMBL
	A0A8I3QD57_CANLF	UniProtKB/TrEMBL
	A0A8I3QD83_CANLF	UniProtKB/TrEMBL
	A0A8P0N9P2_CANLF	UniProtKB/TrEMBL
	A0A8P0PBQ4_CANLF	UniProtKB/TrEMBL
	A0A8P0PC30_CANLF	UniProtKB/TrEMBL
	A0A8P0PEV0_CANLF	UniProtKB/TrEMBL
	NR4A1_CANLF	UniProtKB/Swiss-Prot, ENTREZGENE
VGNC ID	VGNC:43954	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Send us a Message

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD