MIR590 (microRNA mir-590) - Rat Genome Database

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Gene: MIR590 (microRNA mir-590) Canis lupus familiaris
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Symbol: MIR590 (Ensembl: cfa-mir-590)
Name: microRNA mir-590 (Ensembl:cfa-mir-590)
RGD ID: 12322241
Description: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
Type: ncrna (Ensembl: miRNA)
RefSeq Status: PROVISIONAL
Previously known as: cfa-mir-590; microRNA 590
RGD Orthologs
Human
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.166,186,538 - 6,186,598 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl66,186,538 - 6,186,598 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha67,884,630 - 7,884,690 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.066,000,974 - 6,001,034 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
UMICH_Zoey_3.165,991,916 - 5,991,976 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.065,939,653 - 5,939,713 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.066,103,177 - 6,103,237 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
JBrowse:




References
Additional References at PubMed
PMID:16381832   PMID:18392026   PMID:19398468  


Genomics

Comparative Map Data
MIR590
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.166,186,538 - 6,186,598 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl66,186,538 - 6,186,598 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha67,884,630 - 7,884,690 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.066,000,974 - 6,001,034 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
UMICH_Zoey_3.165,991,916 - 5,991,976 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.065,939,653 - 5,939,713 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.066,103,177 - 6,103,237 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
MIR590
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38774,191,198 - 74,191,294 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl774,191,198 - 74,191,294 (+)Ensemblhg38GRCh38
GRCh37773,605,528 - 73,605,624 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36773,243,463 - 73,243,559 (+)NCBIBuild 36Build 36hg18NCBI36
Celera769,084,962 - 69,085,058 (+)NCBICelera
Cytogenetic Map7q11.23NCBI
HuRef769,486,996 - 69,487,092 (+)NCBIHuRef
CHM1_1773,750,612 - 73,750,708 (+)NCBICHM1_1
T2T-CHM13v2.0775,393,197 - 75,393,293 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2772,938,600 - 72,938,696 (+)NCBI

Variants

.
Variants in MIR590
2 total Variants

Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSCAFT00000063951
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl66,186,538 - 6,186,598 (-)Ensembl
RefSeq Acc Id: NR_049341
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.166,186,538 - 6,186,598 (-)NCBI
Dog10K_Boxer_Tasha67,884,630 - 7,884,690 (-)NCBI
ROS_Cfam_1.066,000,974 - 6,001,034 (-)NCBI
UMICH_Zoey_3.165,991,916 - 5,991,976 (-)NCBI
UNSW_CanFamBas_1.065,939,653 - 5,939,713 (-)NCBI
UU_Cfam_GSD_1.066,103,177 - 6,103,237 (-)NCBI
Sequence:

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000042120 Ensembl
miRBase MI0008114 ENTREZGENE
NCBI Gene MIR590 ENTREZGENE
RNAcentral URS0000272039 RNACentral
  URS00007E365D RNACentral
  URS00021ED9D9 RNACentral


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-04-02 MIR590  microRNA mir-590    microRNA 590  Symbol and/or name change 5135510 APPROVED