SNX3 (sorting nexin 3) - Rat Genome Database

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Gene: SNX3 (sorting nexin 3) Canis lupus familiaris
Analyze
Symbol: SNX3
Name: sorting nexin 3
RGD ID: 12322152
Description: ENCODES a protein that exhibits phosphatidylinositol-3,5-bisphosphate binding (ortholog); phosphatidylinositol-4-phosphate binding (ortholog); phosphatidylinositol-5-phosphate binding (ortholog); INVOLVED IN hemoglobin biosynthetic process (ortholog); positive regulation of neuron projection development (ortholog); regulation of intracellular protein transport (ortholog); PARTICIPATES IN retromer-mediated pathway; ASSOCIATED WITH Charcot-Marie-Tooth disease type 4 (ortholog); COVID-19 (ortholog); FOUND IN clathrin-coated vesicle (inferred); cytoplasm (inferred); cytoplasmic vesicle (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: sorting nexin-3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11265,252,175 - 65,294,620 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1265,252,175 - 65,294,611 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1265,067,774 - 65,110,209 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01266,127,936 - 66,170,477 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1266,127,942 - 66,170,467 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11265,483,130 - 65,525,574 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01265,329,591 - 65,371,812 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01265,602,544 - 65,644,998 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
SNX3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11265,252,175 - 65,294,620 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1265,252,175 - 65,294,611 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1265,067,774 - 65,110,209 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01266,127,936 - 66,170,477 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1266,127,942 - 66,170,467 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11265,483,130 - 65,525,574 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01265,329,591 - 65,371,812 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01265,602,544 - 65,644,998 (-)NCBIUU_Cfam_GSD_1.0
SNX3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386108,211,222 - 108,261,040 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6108,211,222 - 108,261,246 (-)EnsemblGRCh38hg38GRCh38
GRCh376108,532,426 - 108,582,244 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 366108,639,410 - 108,689,156 (-)NCBINCBI36Build 36hg18NCBI36
Build 346108,639,410 - 108,689,156NCBI
Celera6109,279,209 - 109,328,955 (-)NCBICelera
Cytogenetic Map6q21NCBI
HuRef6106,100,989 - 106,150,564 (-)NCBIHuRef
CHM1_16108,795,674 - 108,845,435 (-)NCBICHM1_1
T2T-CHM13v2.06109,388,338 - 109,438,159 (-)NCBIT2T-CHM13v2.0
Snx3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391042,378,050 - 42,411,365 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1042,378,026 - 42,411,377 (+)EnsemblGRCm39 Ensembl
GRCm381042,502,054 - 42,535,369 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1042,502,030 - 42,535,381 (+)EnsemblGRCm38mm10GRCm38
MGSCv371042,221,860 - 42,255,175 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361042,190,444 - 42,223,782 (+)NCBIMGSCv36mm8
Celera1043,369,479 - 43,403,088 (+)NCBICelera
Cytogenetic Map10B2NCBI
cM Map1022.89NCBI
Snx3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82047,574,051 - 47,607,577 (+)NCBIGRCr8
mRatBN7.22045,992,446 - 46,025,361 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2045,992,720 - 46,025,379 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2047,710,148 - 47,742,787 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02047,360,312 - 47,392,951 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02048,053,233 - 48,086,017 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02047,225,382 - 47,263,390 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2047,225,619 - 47,263,390 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02048,923,090 - 48,932,814 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera2053,947,195 - 53,979,808 (-)NCBICelera
Cytogenetic Map20q13NCBI
Snx3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541133,340,274 - 33,345,500 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541133,339,974 - 33,344,563 (-)NCBIChiLan1.0ChiLan1.0
SNX3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25128,216,245 - 128,269,590 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16126,106,433 - 126,156,957 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06106,010,633 - 106,063,331 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16109,874,095 - 109,924,185 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6109,874,105 - 109,924,185 (-)Ensemblpanpan1.1panPan2
Snx3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946100,197,614 - 100,245,855 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365644,471,652 - 4,520,785 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365644,472,171 - 4,520,732 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SNX3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl174,306,455 - 74,349,335 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1174,306,450 - 74,349,735 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2183,576,787 - 83,585,208 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SNX3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11365,590,413 - 65,640,368 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1365,589,801 - 65,640,876 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604037,916,042 - 37,966,796 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Snx3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478014,043,003 - 14,080,380 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462478014,043,002 - 14,080,380 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in SNX3
586 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 23 22 16 6 6 6 6 33 22 12 14 10

Sequence


Ensembl Acc Id: ENSCAFT00000006070   ⟹   ENSCAFP00000005620
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1265,252,408 - 65,294,349 (-)Ensembl
Ensembl Acc Id: ENSCAFT00000073250   ⟹   ENSCAFP00000046757
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1265,252,408 - 65,294,611 (-)Ensembl
Ensembl Acc Id: ENSCAFT00000077968   ⟹   ENSCAFP00000060714
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1265,252,175 - 65,294,610 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845016176   ⟹   ENSCAFP00845012582
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1266,127,942 - 66,170,203 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845016209   ⟹   ENSCAFP00845012609
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1266,127,948 - 66,170,219 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845016248   ⟹   ENSCAFP00845012641
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1266,128,529 - 66,170,467 (-)Ensembl
RefSeq Acc Id: XM_038492566   ⟹   XP_038348494
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11265,483,130 - 65,525,574 (-)NCBI
RefSeq Acc Id: XM_038554879   ⟹   XP_038410807
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01265,602,544 - 65,644,998 (-)NCBI
RefSeq Acc Id: XM_038618752   ⟹   XP_038474680
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01265,329,591 - 65,371,812 (-)NCBI
RefSeq Acc Id: XM_038684314   ⟹   XP_038540242
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01266,127,936 - 66,170,477 (-)NCBI
RefSeq Acc Id: XM_849913   ⟹   XP_855006
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11265,252,175 - 65,294,620 (-)NCBI
Dog10K_Boxer_Tasha1265,067,774 - 65,110,209 (-)NCBI
Sequence:
RefSeq Acc Id: XP_855006   ⟸   XM_849913
- UniProtKB: A0A8C0KZR3 (UniProtKB/TrEMBL),   A0A8C0MYJ8 (UniProtKB/TrEMBL),   A0A8C0R7W4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCAFP00000005620   ⟸   ENSCAFT00000006070
Ensembl Acc Id: ENSCAFP00000060714   ⟸   ENSCAFT00000077968
Ensembl Acc Id: ENSCAFP00000046757   ⟸   ENSCAFT00000073250
RefSeq Acc Id: XP_038348494   ⟸   XM_038492566
RefSeq Acc Id: XP_038474680   ⟸   XM_038618752
RefSeq Acc Id: XP_038540242   ⟸   XM_038684314
- UniProtKB: A0A8C0KZR3 (UniProtKB/TrEMBL),   A0A8C0MYJ8 (UniProtKB/TrEMBL),   A0A8C0R7W4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038410807   ⟸   XM_038554879
- UniProtKB: A0A8C0KZR3 (UniProtKB/TrEMBL),   A0A8C0MYJ8 (UniProtKB/TrEMBL),   A0A8C0R7W4 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCAFP00845012582   ⟸   ENSCAFT00845016176
Ensembl Acc Id: ENSCAFP00845012641   ⟸   ENSCAFT00845016248
Ensembl Acc Id: ENSCAFP00845012609   ⟸   ENSCAFT00845016209
Protein Domains
PX

Promoters
RGD ID:13685523
Promoter ID:EPDNEW_C3592
Type:initiation region
Name:SNX3_1
Description:sorting nexin 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11265,294,443 - 65,294,503EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000003772 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030010109 UniProtKB/TrEMBL
  ENSCAFG00040010170 UniProtKB/TrEMBL
  ENSCAFG00845009178 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000006070.5 UniProtKB/TrEMBL
  ENSCAFT00000077968.2 UniProtKB/TrEMBL
  ENSCAFT00030018770.1 UniProtKB/TrEMBL
  ENSCAFT00030018874.1 UniProtKB/TrEMBL
  ENSCAFT00040018933.1 UniProtKB/TrEMBL
  ENSCAFT00845016176 ENTREZGENE
  ENSCAFT00845016176.1 UniProtKB/TrEMBL
  ENSCAFT00845016209.1 UniProtKB/TrEMBL
  ENSCAFT00845016248.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.1520.10 UniProtKB/TrEMBL
InterPro PX_dom UniProtKB/TrEMBL
  PX_dom_sf UniProtKB/TrEMBL
  PX_SNX3_Vert UniProtKB/TrEMBL
  Sorting_Nexin UniProtKB/TrEMBL
KEGG Report cfa:613007 UniProtKB/TrEMBL
NCBI Gene SNX3 ENTREZGENE
PANTHER RE52028P UniProtKB/TrEMBL
  SORTING NEXIN-3 UniProtKB/TrEMBL
Pfam PF00787 UniProtKB/TrEMBL
PROSITE PS50195 UniProtKB/TrEMBL
SMART SM00312 UniProtKB/TrEMBL
Superfamily-SCOP SSF64268 UniProtKB/TrEMBL
UniProt A0A8C0KZR3 ENTREZGENE
  A0A8C0MYJ8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0MYQ3_CANLF UniProtKB/TrEMBL
  A0A8C0R7W4 ENTREZGENE
  A0A8I3N1L7_CANLF UniProtKB/TrEMBL
  A0A8I3NAU9_CANLF UniProtKB/TrEMBL
  A0A8I3NB79_CANLF UniProtKB/TrEMBL
  A0A8P0P9L2_CANLF UniProtKB/TrEMBL
VGNC ID VGNC:46636 ENTREZGENE