SLC37A4 (solute carrier family 37 member 4) - Rat Genome Database

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Gene: SLC37A4 (solute carrier family 37 member 4) Canis lupus familiaris
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Symbol: SLC37A4
Name: solute carrier family 37 member 4
RGD ID: 12316800
Description: ENCODES a protein that exhibits glucose-6-phosphate transmembrane transporter activity (ortholog); INVOLVED IN glucose homeostasis (ortholog); glucose-6-phosphate transport (ortholog); positive regulation of catalytic activity (ortholog); PARTICIPATES IN electron transport chain pathway; fructose-1,6-bisphosphatase deficiency pathway; gluconeogenesis pathway; ASSOCIATED WITH CD3epsilon deficiency (ortholog); chromosome 11 partial duplication syndrome (ortholog); congenital disorder of glycosylation (ortholog); FOUND IN endoplasmic reticulum membrane (ortholog)
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: glucose-6-phosphate exchanger SLC37A4; glucose-6-phosphate translocase; solute carrier family 37 (glycerol-6-phosphate transporter), member 4
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1514,823,485 - 14,830,007 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl514,823,499 - 14,830,004 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha514,876,420 - 14,882,925 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0514,766,724 - 14,773,278 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl514,766,743 - 14,773,278 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1514,905,007 - 14,911,527 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0514,808,746 - 14,815,273 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0514,849,134 - 14,855,669 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:11551847   PMID:30032202  


Genomics

Comparative Map Data
SLC37A4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1514,823,485 - 14,830,007 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl514,823,499 - 14,830,004 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha514,876,420 - 14,882,925 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0514,766,724 - 14,773,278 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl514,766,743 - 14,773,278 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1514,905,007 - 14,911,527 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0514,808,746 - 14,815,273 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0514,849,134 - 14,855,669 (+)NCBIUU_Cfam_GSD_1.0
SLC37A4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811119,024,112 - 119,030,877 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl11119,023,751 - 119,030,906 (-)EnsemblGRCh38hg38GRCh38
GRCh3711118,894,822 - 118,901,587 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3611118,400,274 - 118,406,800 (-)NCBINCBI36Build 36hg18NCBI36
Build 3411118,400,273 - 118,406,629NCBI
Celera11116,053,114 - 116,059,668 (-)NCBICelera
Cytogenetic Map11q23.3NCBI
HuRef11114,834,720 - 114,841,274 (-)NCBIHuRef
CHM1_111118,781,352 - 118,787,906 (-)NCBICHM1_1
T2T-CHM13v2.011119,044,474 - 119,051,238 (-)NCBIT2T-CHM13v2.0
Slc37a4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39944,308,243 - 44,314,263 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl944,308,149 - 44,314,265 (+)EnsemblGRCm39 Ensembl
GRCm38944,396,946 - 44,402,966 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl944,396,852 - 44,402,968 (+)EnsemblGRCm38mm10GRCm38
MGSCv37944,206,259 - 44,211,049 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36944,149,171 - 44,153,961 (+)NCBIMGSCv36mm8
Celera941,645,753 - 41,650,553 (+)NCBICelera
Cytogenetic Map9A5.2NCBI
cM Map924.84NCBI
Slc37a4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8853,619,952 - 53,626,110 (+)NCBIGRCr8
mRatBN7.2844,723,216 - 44,729,301 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl844,723,339 - 44,729,301 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx850,219,432 - 50,225,517 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0848,498,149 - 48,504,234 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0846,368,147 - 46,374,232 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0848,716,914 - 48,723,024 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl848,716,939 - 48,723,024 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0847,335,891 - 47,341,995 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4847,363,896 - 47,369,981 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1847,372,661 - 47,378,744 (+)NCBI
Celera844,309,446 - 44,315,531 (+)NCBICelera
Cytogenetic Map8q22NCBI
Slc37a4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541220,133,652 - 20,139,542 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541220,133,652 - 20,140,134 (-)NCBIChiLan1.0ChiLan1.0
SLC37A4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v29119,729,117 - 119,736,189 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan111120,832,867 - 120,840,028 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v011113,862,537 - 113,869,447 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.111117,792,700 - 117,799,269 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11117,792,700 - 117,799,269 (-)Ensemblpanpan1.1panPan2
Slc37a4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947101,058,817 - 101,065,693 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365423,980,236 - 3,987,066 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365423,980,538 - 3,987,039 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC37A4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl946,247,282 - 46,254,031 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1946,247,278 - 46,254,068 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2951,282,374 - 51,289,162 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SLC37A4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11110,396,133 - 110,402,737 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1110,395,612 - 110,401,358 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604315,631,589 - 15,638,169 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Slc37a4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478414,415,395 - 14,421,944 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462478414,415,385 - 14,421,953 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in SLC37A4
115 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 23 22 16 6 6 6 6 33 22 12 14 10

Sequence


Ensembl Acc Id: ENSCAFT00000019651   ⟹   ENSCAFP00000018226
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl514,823,499 - 14,830,004 (+)Ensembl
Ensembl Acc Id: ENSCAFT00000043260   ⟹   ENSCAFP00000040270
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl514,823,499 - 14,830,004 (+)Ensembl
Ensembl Acc Id: ENSCAFT00000069506   ⟹   ENSCAFP00000051720
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl514,823,499 - 14,830,004 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845001567   ⟹   ENSCAFP00845001237
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl514,766,743 - 14,773,278 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845001593   ⟹   ENSCAFP00845001262
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl514,766,743 - 14,773,278 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845001620   ⟹   ENSCAFP00845001282
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl514,766,743 - 14,773,278 (+)Ensembl
RefSeq Acc Id: NM_001287131   ⟹   NP_001274060
RefSeq Status: VALIDATED
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1514,823,499 - 14,830,004 (+)NCBI
Dog10K_Boxer_Tasha514,876,420 - 14,882,925 (+)NCBI
ROS_Cfam_1.0514,766,743 - 14,773,278 (+)NCBI
UMICH_Zoey_3.1514,905,007 - 14,911,527 (+)NCBI
UNSW_CanFamBas_1.0514,808,746 - 14,815,273 (+)NCBI
UU_Cfam_GSD_1.0514,849,134 - 14,855,669 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038664144   ⟹   XP_038520072
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0514,766,724 - 14,773,276 (+)NCBI
RefSeq Acc Id: XM_038664145   ⟹   XP_038520073
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0514,767,297 - 14,772,724 (+)NCBI
RefSeq Acc Id: XM_038664146   ⟹   XP_038520074
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0514,767,497 - 14,772,724 (+)NCBI
RefSeq Acc Id: NP_001274060   ⟸   NM_001287131
- UniProtKB: A0A8C0M9B8 (UniProtKB/TrEMBL),   A0A8C0KJ88 (UniProtKB/TrEMBL),   A0A8I3MHL8 (UniProtKB/TrEMBL),   A0A8I3MH00 (UniProtKB/TrEMBL),   A0A8P0P1H1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCAFP00000051720   ⟸   ENSCAFT00000069506
Ensembl Acc Id: ENSCAFP00000018226   ⟸   ENSCAFT00000019651
Ensembl Acc Id: ENSCAFP00000040270   ⟸   ENSCAFT00000043260
RefSeq Acc Id: XP_038520072   ⟸   XM_038664144
- Peptide Label: isoform X1
- UniProtKB: A0A8C0RCB6 (UniProtKB/TrEMBL),   A0A8I3MHK0 (UniProtKB/TrEMBL),   A0A8I3MH00 (UniProtKB/TrEMBL),   A0A8P0P1H1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038520073   ⟸   XM_038664145
- Peptide Label: isoform X1
- UniProtKB: A0A8C0RCB6 (UniProtKB/TrEMBL),   A0A8I3MHK0 (UniProtKB/TrEMBL),   A0A8I3MH00 (UniProtKB/TrEMBL),   A0A8P0P1H1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038520074   ⟸   XM_038664146
- Peptide Label: isoform X1
- UniProtKB: A0A8C0RCB6 (UniProtKB/TrEMBL),   A0A8I3MHK0 (UniProtKB/TrEMBL),   A0A8I3MH00 (UniProtKB/TrEMBL),   A0A8P0P1H1 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCAFP00845001237   ⟸   ENSCAFT00845001567
Ensembl Acc Id: ENSCAFP00845001282   ⟸   ENSCAFT00845001620
Ensembl Acc Id: ENSCAFP00845001262   ⟸   ENSCAFT00845001593
Promoters
RGD ID:13683126
Promoter ID:EPDNEW_C1193
Type:initiation region
Name:SLC37A4_2
Description:solute carrier family 37 member 4
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_C1194  
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1514,823,543 - 14,823,603EPDNEW
RGD ID:13683127
Promoter ID:EPDNEW_C1194
Type:initiation region
Name:SLC37A4_1
Description:solute carrier family 37 member 4
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_C1193  
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1514,824,892 - 14,824,952EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000012380 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030004138 UniProtKB/TrEMBL
  ENSCAFG00040021419 UniProtKB/TrEMBL
  ENSCAFG00845000912 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000019651.4 UniProtKB/TrEMBL
  ENSCAFT00000043260.4 UniProtKB/TrEMBL
  ENSCAFT00000069506.2 UniProtKB/TrEMBL
  ENSCAFT00030007649.1 UniProtKB/TrEMBL
  ENSCAFT00030007693.1 UniProtKB/TrEMBL
  ENSCAFT00040039805.1 UniProtKB/TrEMBL
  ENSCAFT00040039842.1 UniProtKB/TrEMBL
  ENSCAFT00845001567 ENTREZGENE
  ENSCAFT00845001567.1 UniProtKB/TrEMBL
  ENSCAFT00845001593 ENTREZGENE
  ENSCAFT00845001593.1 UniProtKB/TrEMBL
  ENSCAFT00845001620.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1250.20 UniProtKB/TrEMBL
InterPro MFS UniProtKB/TrEMBL
  MFS_dom UniProtKB/TrEMBL
  MFS_trans_sf UniProtKB/TrEMBL
  OPA_Antiporter UniProtKB/TrEMBL
  Sugar-P_transporter_CS UniProtKB/TrEMBL
  Sugar_P_transporter UniProtKB/TrEMBL
KEGG Report cfa:489375 UniProtKB/TrEMBL
NCBI Gene SLC37A4 ENTREZGENE
PANTHER GLUCOSE-6-PHOSPHATE EXCHANGER SLC37A4 UniProtKB/TrEMBL
  GLUCOSE-6-PHOSPHATE EXCHANGER SLC37A4 UniProtKB/TrEMBL
Pfam MFS_1 UniProtKB/TrEMBL
PIRSF Hexose_phosphate_transp UniProtKB/TrEMBL
PROSITE GLPT UniProtKB/TrEMBL
  MFS UniProtKB/TrEMBL
Superfamily-SCOP SSF103473 UniProtKB/TrEMBL
UniProt A0A8C0KJ88 ENTREZGENE
  A0A8C0M9B8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0RCB6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3MH00 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3MHK0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3MHL8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0P1H1 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:46389 ENTREZGENE