UCK2 (uridine-cytidine kinase 2) - Rat Genome Database

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Gene: UCK2 (uridine-cytidine kinase 2) Canis lupus familiaris
Analyze
Symbol: UCK2
Name: uridine-cytidine kinase 2
RGD ID: 12306870
Description: ENCODES a protein that exhibits ATP binding (inferred); cytidine kinase activity (inferred); identical protein binding (inferred); INVOLVED IN cellular response to oxygen levels (ortholog); feeding behavior (ortholog); response to axon injury (ortholog); ASSOCIATED WITH Animal Disease Models (ortholog); Experimental Diabetes Mellitus (ortholog); gastrointestinal stromal tumor (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13817,475,789 - 17,555,926 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3817,479,558 - 17,579,675 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3817,535,557 - 17,602,054 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03817,534,582 - 17,601,221 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3817,531,134 - 17,634,890 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13817,532,294 - 17,598,816 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03817,883,407 - 17,949,905 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03818,177,313 - 18,243,863 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IBA)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
UCK2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13817,475,789 - 17,555,926 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3817,479,558 - 17,579,675 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3817,535,557 - 17,602,054 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03817,534,582 - 17,601,221 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3817,531,134 - 17,634,890 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13817,532,294 - 17,598,816 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03817,883,407 - 17,949,905 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03818,177,313 - 18,243,863 (-)NCBIUU_Cfam_GSD_1.0
UCK2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381165,827,614 - 165,911,618 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1165,827,614 - 165,911,618 (+)EnsemblGRCh38hg38GRCh38
GRCh371165,796,851 - 165,880,855 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361164,063,514 - 164,143,967 (+)NCBINCBI36Build 36hg18NCBI36
Celera1138,902,284 - 138,982,715 (+)NCBICelera
Cytogenetic Map1q24.1NCBI
HuRef1137,044,441 - 137,128,457 (+)NCBIHuRef
CHM1_11167,219,021 - 167,303,066 (+)NCBICHM1_1
T2T-CHM13v2.01165,173,785 - 165,257,744 (+)NCBIT2T-CHM13v2.0
Uck2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391167,050,464 - 167,112,657 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1167,050,452 - 167,112,889 (-)EnsemblGRCm39 Ensembl
GRCm381167,222,895 - 167,285,933 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1167,222,883 - 167,285,320 (-)EnsemblGRCm38mm10GRCm38
MGSCv371169,156,214 - 169,215,258 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361169,062,758 - 169,121,802 (-)NCBIMGSCv36mm8
Celera1169,643,034 - 169,702,477 (-)NCBICelera
Cytogenetic Map1H2.3NCBI
cM Map174.61NCBI
Uck2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81381,913,732 - 81,971,036 (-)NCBIGRCr8
mRatBN7.21379,380,807 - 79,438,121 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1379,383,846 - 79,438,352 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1382,013,671 - 82,068,184 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01383,321,316 - 83,375,604 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01380,558,961 - 80,613,449 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01385,376,716 - 85,443,976 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1385,376,716 - 85,443,976 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.013101,428,775 - 101,429,259 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01390,035,485 - 90,087,109 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41382,892,893 - 82,949,575 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11382,907,443 - 82,914,725 (-)NCBI
Celera1379,089,479 - 79,143,648 (-)NCBICelera
Cytogenetic Map13q24NCBI
Uck2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546210,815,389 - 10,886,227 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495546210,815,496 - 10,925,364 (-)NCBIChiLan1.0ChiLan1.0
UCK2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2183,854,536 - 83,940,003 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1183,522,848 - 83,608,323 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01141,259,057 - 141,343,122 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11145,110,561 - 145,131,894 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1145,110,434 - 145,131,894 (+)Ensemblpanpan1.1panPan2
Uck2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344101,658,728 - 101,713,313 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648119,505,459 - 19,560,083 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648119,505,477 - 19,560,035 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
UCK2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl484,838,802 - 84,919,236 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1484,838,793 - 84,919,231 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
UCK2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12562,974,515 - 63,059,436 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2562,974,257 - 63,059,414 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605564,729,768 - 64,814,746 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Uck2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248264,163,798 - 4,229,640 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248264,163,830 - 4,243,048 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in UCK2
1271 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 23 22 16 6 6 6 6 33 22 12 14 10

Sequence


Ensembl Acc Id: ENSCAFT00000021389   ⟹   ENSCAFP00000019858
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl3817,479,558 - 17,579,675 (-)Ensembl
Ensembl Acc Id: ENSCAFT00000065977   ⟹   ENSCAFP00000062318
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl3817,479,558 - 17,497,313 (-)Ensembl
Ensembl Acc Id: ENSCAFT00000073513   ⟹   ENSCAFP00000045657
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl3817,479,558 - 17,579,675 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845042981   ⟹   ENSCAFP00845033695
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl3817,531,134 - 17,601,213 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845043042   ⟹   ENSCAFP00845033745
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl3817,531,134 - 17,574,220 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845043129   ⟹   ENSCAFP00845033814
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl3817,531,139 - 17,634,890 (-)Ensembl
RefSeq Acc Id: XM_038448531   ⟹   XP_038304459
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.03817,534,582 - 17,601,221 (-)NCBI
RefSeq Acc Id: XM_038464094   ⟹   XP_038320022
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha3817,535,557 - 17,602,054 (-)NCBI
RefSeq Acc Id: XM_038522421   ⟹   XP_038378349
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.13817,532,294 - 17,598,816 (-)NCBI
RefSeq Acc Id: XM_038586213   ⟹   XP_038442141
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.03818,177,313 - 18,243,863 (-)NCBI
RefSeq Acc Id: XM_038650626   ⟹   XP_038506554
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.03817,883,407 - 17,949,905 (-)NCBI
Ensembl Acc Id: ENSCAFP00000019858   ⟸   ENSCAFT00000021389
Ensembl Acc Id: ENSCAFP00000045657   ⟸   ENSCAFT00000073513
Ensembl Acc Id: ENSCAFP00000062318   ⟸   ENSCAFT00000065977
RefSeq Acc Id: XP_038378349   ⟸   XM_038522421
RefSeq Acc Id: XP_038506554   ⟸   XM_038650626
RefSeq Acc Id: XP_038304459   ⟸   XM_038448531
- UniProtKB: A0A8C0QTV6 (UniProtKB/TrEMBL),   A0A8C0Z0Q7 (UniProtKB/TrEMBL),   A0A8I3S4I7 (UniProtKB/TrEMBL),   A0A8I3PHX7 (UniProtKB/TrEMBL),   A0A8P0PN73 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038320022   ⟸   XM_038464094
- UniProtKB: A0A8C0QTV6 (UniProtKB/TrEMBL),   A0A8C0Z0Q7 (UniProtKB/TrEMBL),   A0A8I3S4I7 (UniProtKB/TrEMBL),   A0A8I3PHX7 (UniProtKB/TrEMBL),   A0A8P0PN73 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038442141   ⟸   XM_038586213
- UniProtKB: A0A8C0QTV6 (UniProtKB/TrEMBL),   A0A8C0Z0Q7 (UniProtKB/TrEMBL),   A0A8I3PHX7 (UniProtKB/TrEMBL),   A0A8I3S4I7 (UniProtKB/TrEMBL),   A0A8P0PN73 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCAFP00845033814   ⟸   ENSCAFT00845043129
Ensembl Acc Id: ENSCAFP00845033745   ⟸   ENSCAFT00845043042
Ensembl Acc Id: ENSCAFP00845033695   ⟸   ENSCAFT00845042981
Protein Domains
Phosphoribulokinase/uridine kinase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000013489 Ensembl
  ENSCAFG00000056546 UniProtKB/TrEMBL
  ENSCAFG00030020721 UniProtKB/TrEMBL
  ENSCAFG00040017541 UniProtKB/TrEMBL
  ENSCAFG00845024343 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000105326.1 UniProtKB/TrEMBL
  ENSCAFT00000106864.1 UniProtKB/TrEMBL
  ENSCAFT00030038115.1 UniProtKB/TrEMBL
  ENSCAFT00040032487.1 UniProtKB/TrEMBL
  ENSCAFT00845042981 ENTREZGENE
  ENSCAFT00845042981.1 UniProtKB/TrEMBL
  ENSCAFT00845043042.1 UniProtKB/TrEMBL
  ENSCAFT00845043129.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
InterPro P-loop_NTPase UniProtKB/TrEMBL
  PRK/URK UniProtKB/TrEMBL
  Uridine_kinase-like UniProtKB/TrEMBL
NCBI Gene UCK2 ENTREZGENE
PANTHER URIDINE KINASE UniProtKB/TrEMBL
Pfam PRK UniProtKB/TrEMBL
PRINTS URIDINKINASE UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A8C0QTV6 ENTREZGENE
  A0A8C0Z0Q7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3PHX7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3S4I7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3S8M9_CANLF UniProtKB/TrEMBL
  A0A8P0PN73 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:56145 ENTREZGENE