NELFCD (negative elongation factor complex member C/D) - Rat Genome Database

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Gene: NELFCD (negative elongation factor complex member C/D) Canis lupus familiaris
Analyze
Symbol: NELFCD
Name: negative elongation factor complex member C/D
RGD ID: 12296173
Description: INVOLVED IN negative regulation of DNA-templated transcription (inferred); negative regulation of transcription elongation by RNA polymerase II (inferred); PARTICIPATES IN RNA polymerase II transcription elongation pathway; ASSOCIATED WITH amyotrophic lateral sclerosis type 8 (ortholog); prostate cancer (ortholog); FOUND IN NELF complex (inferred); nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: negative elongation factor C/D; negative elongation factor D-like; TH1-like; TH1L
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12443,685,356 - 43,743,239 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2443,734,236 - 43,743,233 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2442,976,753 - 42,989,365 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02444,596,768 - 44,609,381 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2444,596,635 - 44,609,369 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12443,700,324 - 43,712,935 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02443,819,006 - 43,831,619 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02444,478,807 - 44,491,418 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
NELF complex  (IBA,IEA)
nucleus  (IEA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
NELFCD
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12443,685,356 - 43,743,239 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2443,734,236 - 43,743,233 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2442,976,753 - 42,989,365 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02444,596,768 - 44,609,381 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2444,596,635 - 44,609,369 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12443,700,324 - 43,712,935 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02443,819,006 - 43,831,619 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02444,478,807 - 44,491,418 (+)NCBIUU_Cfam_GSD_1.0
NELFCD
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382058,981,256 - 58,995,113 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2058,981,208 - 58,995,133 (+)EnsemblGRCh38hg38GRCh38
GRCh372057,556,311 - 57,570,168 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362056,989,706 - 57,003,583 (+)NCBINCBI36Build 36hg18NCBI36
Build 342056,989,705 - 57,003,581NCBI
Celera2054,296,740 - 54,310,603 (+)NCBICelera
Cytogenetic Map20q13.32NCBI
HuRef2054,343,186 - 54,357,094 (+)NCBIHuRef
CHM1_12057,457,652 - 57,471,577 (+)NCBICHM1_1
T2T-CHM13v2.02060,764,380 - 60,778,214 (+)NCBIT2T-CHM13v2.0
Nelfcd
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392174,257,623 - 174,269,298 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2174,257,597 - 174,269,295 (+)EnsemblGRCm39 Ensembl
GRCm382174,415,804 - 174,427,505 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2174,415,804 - 174,427,502 (+)EnsemblGRCm38mm10GRCm38
MGSCv372174,241,305 - 174,253,003 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362174,058,743 - 174,070,436 (+)NCBIMGSCv36mm8
Celera2180,375,996 - 180,388,332 (+)NCBICelera
Cytogenetic Map2H4NCBI
cM Map297.93NCBI
Nelfcd
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83183,631,968 - 183,643,088 (+)NCBIGRCr8
mRatBN7.23163,213,765 - 163,224,886 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3163,213,762 - 163,224,884 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3167,012,506 - 167,023,627 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03175,508,965 - 175,520,084 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03173,253,352 - 173,264,473 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03172,510,840 - 172,527,118 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3172,510,874 - 172,526,740 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03178,565,103 - 178,574,630 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera3162,387,255 - 162,398,373 (+)NCBICelera
Cytogenetic Map3q43NCBI
Nelfcd
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955445597,826 - 610,134 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955445597,826 - 610,134 (-)NCBIChiLan1.0ChiLan1.0
NELFCD
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22164,744,607 - 64,758,512 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12064,737,729 - 64,751,634 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02055,332,309 - 55,346,167 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12056,697,394 - 56,706,458 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2056,693,685 - 56,706,458 (+)Ensemblpanpan1.1panPan2
Nelfcd
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640181,824,278 - 181,832,136 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365301,474,136 - 1,481,567 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365301,474,097 - 1,481,943 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NELFCD
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1759,129,076 - 59,141,499 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11759,129,055 - 59,141,499 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21766,499,448 - 66,511,907 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NELFCD
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.125,146,137 - 5,159,965 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl25,146,575 - 5,159,883 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605053,197,345 - 53,211,173 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nelfcd
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474125,267,359 - 25,280,844 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474125,267,334 - 25,280,844 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in NELFCD
646 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 23 22 16 6 6 6 6 33 22 12 14 10

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005635238 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038434232 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038434233 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038434234 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038457727 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038457728 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038457729 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038509389 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038509391 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038509392 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038572734 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038572735 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038572736 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038637013 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038637014 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038637015 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000024 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000269 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000063 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000376 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000024 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSCAFT00000019342   ⟹   ENSCAFP00000017940
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2443,734,236 - 43,743,233 (+)Ensembl
Ensembl Acc Id: ENSCAFT00000092216   ⟹   ENSCAFP00000053064
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2443,734,236 - 43,743,227 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845024978   ⟹   ENSCAFP00845019648
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2444,596,635 - 44,609,361 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845025023   ⟹   ENSCAFP00845019684
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2444,598,664 - 44,609,369 (+)Ensembl
RefSeq Acc Id: XM_038434232   ⟹   XP_038290160
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02444,596,768 - 44,609,381 (+)NCBI
RefSeq Acc Id: XM_038434233   ⟹   XP_038290161
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02444,596,770 - 44,609,381 (+)NCBI
RefSeq Acc Id: XM_038434234   ⟹   XP_038290162
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02444,596,768 - 44,609,381 (+)NCBI
RefSeq Acc Id: XM_038457727   ⟹   XP_038313655
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha2442,976,753 - 42,989,365 (+)NCBI
RefSeq Acc Id: XM_038457728   ⟹   XP_038313656
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha2442,976,755 - 42,989,365 (+)NCBI
RefSeq Acc Id: XM_038457729   ⟹   XP_038313657
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha2442,976,753 - 42,989,365 (+)NCBI
RefSeq Acc Id: XM_038509389   ⟹   XP_038365317
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12443,700,324 - 43,712,935 (+)NCBI
RefSeq Acc Id: XM_038509391   ⟹   XP_038365319
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12443,700,326 - 43,712,935 (+)NCBI
RefSeq Acc Id: XM_038509392   ⟹   XP_038365320
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12443,700,324 - 43,712,935 (+)NCBI
RefSeq Acc Id: XM_038572734   ⟹   XP_038428662
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02444,478,807 - 44,491,418 (+)NCBI
RefSeq Acc Id: XM_038572735   ⟹   XP_038428663
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02444,478,809 - 44,491,418 (+)NCBI
RefSeq Acc Id: XM_038572736   ⟹   XP_038428664
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02444,478,807 - 44,491,418 (+)NCBI
RefSeq Acc Id: XM_038637013   ⟹   XP_038492941
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02443,819,006 - 43,831,619 (+)NCBI
RefSeq Acc Id: XM_038637014   ⟹   XP_038492942
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02443,819,008 - 43,831,619 (+)NCBI
RefSeq Acc Id: XM_038637015   ⟹   XP_038492943
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02443,819,006 - 43,831,619 (+)NCBI
Ensembl Acc Id: ENSCAFP00000017940   ⟸   ENSCAFT00000019342
Ensembl Acc Id: ENSCAFP00000053064   ⟸   ENSCAFT00000092216
RefSeq Acc Id: XP_038365317   ⟸   XM_038509389
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038365320   ⟸   XM_038509392
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038365319   ⟸   XM_038509391
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038492941   ⟸   XM_038637013
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038492943   ⟸   XM_038637015
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038492942   ⟸   XM_038637014
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038290160   ⟸   XM_038434232
- Peptide Label: isoform X1
- UniProtKB: A0A8C0R5P8 (UniProtKB/TrEMBL),   A0A8C0T9G8 (UniProtKB/TrEMBL),   A0A8I3NUK3 (UniProtKB/TrEMBL),   A0A8C0NVS8 (UniProtKB/TrEMBL),   A0A8I3NUN8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038290162   ⟸   XM_038434234
- Peptide Label: isoform X3
- UniProtKB: A0A8C0NVS8 (UniProtKB/TrEMBL),   A0A8I3NUN8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038290161   ⟸   XM_038434233
- Peptide Label: isoform X2
- UniProtKB: A0A8C0NVS8 (UniProtKB/TrEMBL),   A0A8I3NUN8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038313655   ⟸   XM_038457727
- Peptide Label: isoform X1
- UniProtKB: A0A8C0R5P8 (UniProtKB/TrEMBL),   A0A8C0T9G8 (UniProtKB/TrEMBL),   A0A8I3NUK3 (UniProtKB/TrEMBL),   A0A8C0NVS8 (UniProtKB/TrEMBL),   A0A8I3NUN8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038313657   ⟸   XM_038457729
- Peptide Label: isoform X3
- UniProtKB: A0A8C0NVS8 (UniProtKB/TrEMBL),   A0A8I3NUN8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038313656   ⟸   XM_038457728
- Peptide Label: isoform X2
- UniProtKB: A0A8C0NVS8 (UniProtKB/TrEMBL),   A0A8I3NUN8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038428662   ⟸   XM_038572734
- Peptide Label: isoform X1
- UniProtKB: A0A8C0NVS8 (UniProtKB/TrEMBL),   A0A8C0R5P8 (UniProtKB/TrEMBL),   A0A8C0T9G8 (UniProtKB/TrEMBL),   A0A8I3NUK3 (UniProtKB/TrEMBL),   A0A8I3NUN8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038428664   ⟸   XM_038572736
- Peptide Label: isoform X3
- UniProtKB: A0A8C0NVS8 (UniProtKB/TrEMBL),   A0A8I3NUN8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038428663   ⟸   XM_038572735
- Peptide Label: isoform X2
- UniProtKB: A0A8C0NVS8 (UniProtKB/TrEMBL),   A0A8I3NUN8 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCAFP00845019648   ⟸   ENSCAFT00845024978
Ensembl Acc Id: ENSCAFP00845019684   ⟸   ENSCAFT00845025023


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000012163 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030018840 UniProtKB/TrEMBL
  ENSCAFG00040019541 UniProtKB/TrEMBL
  ENSCAFG00845013969 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000019342.5 UniProtKB/TrEMBL
  ENSCAFT00000092216.2 UniProtKB/TrEMBL
  ENSCAFT00030034699.1 UniProtKB/TrEMBL
  ENSCAFT00030034790.1 UniProtKB/TrEMBL
  ENSCAFT00040036168.1 UniProtKB/TrEMBL
  ENSCAFT00040036247.1 UniProtKB/TrEMBL
  ENSCAFT00845024978 ENTREZGENE
  ENSCAFT00845024978.1 UniProtKB/TrEMBL
  ENSCAFT00845025023.1 UniProtKB/TrEMBL
InterPro TH1 UniProtKB/TrEMBL
NCBI Gene NELFCD ENTREZGENE
PANTHER NEGATIVE ELONGATION FACTOR C/D UniProtKB/TrEMBL
  PTHR12144 UniProtKB/TrEMBL
Pfam TH1 UniProtKB/TrEMBL
UniProt A0A8C0NVS8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0R5P8 ENTREZGENE
  A0A8C0T9G8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3NUK3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3NUN8 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:43738 ENTREZGENE