FANCF (FA complementation group F) - Rat Genome Database

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Gene: FANCF (FA complementation group F) Canis lupus familiaris
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Symbol: FANCF
Name: FA complementation group F
RGD ID: 12249015
Description: ENCODES a protein that exhibits ubiquitin protein ligase activity (ortholog); INVOLVED IN DNA damage response (ortholog); ovarian follicle development (ortholog); protein ubiquitination (ortholog); ASSOCIATED WITH adenocarcinoma in situ (ortholog); breast cancer (ortholog); disease of cellular proliferation (ortholog); FOUND IN chromatin (ortholog); nucleoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Fanconi anemia complementation group F
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12144,253,308 - 44,256,221 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2144,255,134 - 44,256,618 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2143,728,664 - 43,731,582 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02145,370,190 - 45,373,442 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.12144,370,738 - 44,373,650 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02144,542,654 - 44,545,584 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02144,935,521 - 44,938,442 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
FANCF
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12144,253,308 - 44,256,221 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2144,255,134 - 44,256,618 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2143,728,664 - 43,731,582 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02145,370,190 - 45,373,442 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.12144,370,738 - 44,373,650 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02144,542,654 - 44,545,584 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02144,935,521 - 44,938,442 (-)NCBIUU_Cfam_GSD_1.0
FANCF
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381122,622,533 - 22,625,823 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1122,622,533 - 22,625,823 (-)EnsemblGRCh38hg38GRCh38
GRCh371122,644,079 - 22,647,369 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361122,600,655 - 22,603,963 (-)NCBINCBI36Build 36hg18NCBI36
Build 341122,600,654 - 22,603,963NCBI
Celera1122,777,941 - 22,781,250 (-)NCBICelera
Cytogenetic Map11p14.3NCBI
HuRef1122,327,266 - 22,330,575 (-)NCBIHuRef
CHM1_11122,643,695 - 22,647,004 (-)NCBICHM1_1
T2T-CHM13v2.01122,743,288 - 22,746,579 (-)NCBIT2T-CHM13v2.0
Fancf
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39751,510,325 - 51,512,015 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl751,510,325 - 51,512,015 (-)EnsemblGRCm39 Ensembl
GRCm38751,860,577 - 51,862,267 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl751,860,577 - 51,862,267 (-)EnsemblGRCm38mm10GRCm38
MGSCv37759,115,947 - 59,117,637 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36759,115,947 - 59,117,624 (-)NCBIMGSCv36mm8
Celera749,233,676 - 49,235,406 (-)NCBICelera
Cytogenetic Map7B4NCBI
cM Map732.87NCBI
Fancf
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81110,585,054 - 110,587,870 (-)NCBIGRCr8
mRatBN7.21101,449,120 - 101,451,936 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1101,450,389 - 101,451,923 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1106,857,994 - 106,860,810 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01115,329,884 - 115,332,700 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01108,633,029 - 108,635,845 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01107,229,516 - 107,232,321 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1107,231,292 - 107,232,305 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01108,272,291 - 108,274,234 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41101,664,895 - 101,666,720 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera195,615,737 - 95,618,542 (-)NCBICelera
Cytogenetic Map1q22NCBI
Fancf
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554763,067,689 - 3,068,728 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554763,067,491 - 3,069,637 (-)NCBIChiLan1.0ChiLan1.0
FANCF
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2924,912,428 - 24,915,178 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11124,876,586 - 24,881,158 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01122,634,301 - 22,637,885 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11122,542,426 - 22,546,147 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1122,544,052 - 22,545,176 (-)Ensemblpanpan1.1panPan2
Fancf
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494740,625,542 - 40,630,998 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049366543,298,193 - 3,301,251 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FANCF
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl236,884,777 - 36,885,856 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1236,884,701 - 36,886,661 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2240,095,250 - 40,097,471 (+)NCBISscrofa10.2Sscrofa10.2susScr3
FANCF
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1142,377,150 - 42,381,653 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl142,378,883 - 42,380,007 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038139,681,806 - 139,685,541 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fancf
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462476613,583,664 - 13,585,684 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in FANCF
53 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 23 22 16 6 6 6 6 33 22 12 14 10

Sequence


Ensembl Acc Id: ENSCAFT00000047781   ⟹   ENSCAFP00000040041
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2144,255,134 - 44,256,618 (-)Ensembl
RefSeq Acc Id: XM_038429541   ⟹   XP_038285469
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02145,370,190 - 45,373,442 (-)NCBI
RefSeq Acc Id: XM_038456101   ⟹   XP_038312029
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha2143,728,664 - 43,731,582 (-)NCBI
RefSeq Acc Id: XM_038505087   ⟹   XP_038361015
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12144,370,738 - 44,373,650 (-)NCBI
RefSeq Acc Id: XM_038568128   ⟹   XP_038424056
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02144,935,521 - 44,938,442 (-)NCBI
RefSeq Acc Id: XM_038632219   ⟹   XP_038488147
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02144,542,654 - 44,545,584 (-)NCBI
Ensembl Acc Id: ENSCAFP00000040041   ⟸   ENSCAFT00000047781
RefSeq Acc Id: XP_038361015   ⟸   XM_038505087
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038488147   ⟸   XM_038632219
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038285469   ⟸   XM_038429541
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038312029   ⟸   XM_038456101
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038424056   ⟸   XM_038568128
- Peptide Label: isoform X1

Promoters
RGD ID:13687277
Promoter ID:EPDNEW_C5344
Type:multiple initiation site
Name:FANCF_1
Description:Fanconi anemia complementation group F
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12144,256,221 - 44,256,281EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000029498 Ensembl
  ENSCAFG00000057851 UniProtKB/TrEMBL
  ENSCAFG00845023242 UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000107637.1 UniProtKB/TrEMBL
  ENSCAFT00845041005.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.490 UniProtKB/TrEMBL
InterPro FANCF UniProtKB/TrEMBL
  FANCF_C_sf UniProtKB/TrEMBL
NCBI Gene FANCF ENTREZGENE
PANTHER FANCONI ANEMIA GROUP F PROTEIN UniProtKB/TrEMBL
  PTHR14449 UniProtKB/TrEMBL
Pfam FANCF UniProtKB/TrEMBL
UniProt A0A8I3PML5_CANLF UniProtKB/TrEMBL
  A0A8P0PNT3_CANLF UniProtKB/TrEMBL
VGNC ID VGNC:40721 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-05-15 FANCF  FA complementation group F    Fanconi anemia complementation group F  Symbol and/or name change 5135510 APPROVED