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Gene: ZIC3 (Zic family member 3) Canis lupus familiaris

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Symbol:

ZIC3

Name:

Zic family member 3

RGD ID:

12241474

Description:

ENCODES a protein that exhibits sequence-specific DNA binding (ortholog); sequence-specific double-stranded DNA binding (ortholog); INVOLVED IN anterior/posterior pattern specification (ortholog); determination of digestive tract left/right asymmetry (ortholog); determination of left/right symmetry (ortholog); ASSOCIATED WITH autistic disorder (ortholog); autosomal hemophilia A (ortholog); bone development disease (ortholog); FOUND IN nucleoplasm (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

Zic family member 3 (odd-paired homolog, Drosophila); Zic family member 3 heterotaxy 1 (odd-paired homolog, Drosophila); zinc finger protein ZIC 3

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	ZIC3 (Zic family member 3)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Zic3 (zinc finger protein of the cerebellum 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Zic3 (Zic family member 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Zic3 (Zic family member 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	ZIC3 (Zic family member 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Zic3 (Zic family member 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	ZIC3 (Zic family member 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	ZIC3 (Zic family member 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Zic3 (Zic family member 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	ZIC1 (Zic family member 1)	HGNC	OrthoDB

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	X	107,822,002 - 107,833,582 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	X	107,821,948 - 107,833,597 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	X	93,648,940 - 93,660,520 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	X	109,807,663 - 109,819,246 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	X	109,807,645 - 109,818,795 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	X	106,941,593 - 106,953,174 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	X	109,131,179 - 109,142,752 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	X	108,775,722 - 108,787,305 (+)	NCBI		UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autistic disorder (ISO)

autosomal hemophilia A (ISO)

bone development disease (ISO)

Cardiovascular Abnormalities (ISO)

Christianson syndrome (ISO)

Congenital Heart Defects, Multiple Types, 1, X-Linked (ISO)

Craniofacial Abnormalities (ISO)

dextrocardia (ISO)

Facial Asymmetry (ISO)

factor VIII deficiency (ISO)

genetic disease (ISO)

Goldenhar syndrome (ISO)

preaxial polydactyly type IV (ISO)

situs inversus (ISO)

syndromic X-linked intellectual disability Lubs type (ISO)

visceral heterotaxy (ISO)

X-linked hyper IgM syndrome (ISO)

X-linked VACTERL association (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

anterior/posterior pattern specification (IEA,ISO)

atrial cardiac muscle tissue development (IEA)

axial mesoderm development (IEA)

central nervous system development (IBA)

central nervous system segmentation (IEA)

cranial skeletal system development (IEA)

determination of digestive tract left/right asymmetry (ISO)

determination of left/right asymmetry in nervous system (IEA)

determination of left/right symmetry (IEA,ISO)

determination of liver left/right asymmetry (ISO)

determination of pancreatic left/right asymmetry (ISO)

embryonic pattern specification (IEA)

face development (IEA)

forebrain development (IEA)

gastrulation (IEA)

gene expression (IEA)

germ-line stem cell population maintenance (IEA)

heart development (IEA)

heart looping (IEA,ISO)

hippocampus development (IEA)

left/right axis specification (IEA)

left/right pattern formation (IEA)

limb morphogenesis (IEA)

lung development (ISO)

maintenance of cell number (IEA)

mesoderm development (IEA)

mRNA transcription by RNA polymerase II (IEA)

neural plate development (IEA)

neuron differentiation (IEA)

olfactory bulb development (IEA)

outer ear morphogenesis (IEA)

paraxial mesoderm development (IEA)

pattern specification process (IEA,ISO)

positive regulation of DNA-templated transcription (IEA)

positive regulation of transcription by RNA polymerase II (IBA,IEA,ISO)

primitive streak formation (IEA)

regulation of DNA-binding transcription factor activity (ISO)

regulation of transcription by RNA polymerase II (IEA)

skeletal system development (IEA)

smoothened signaling pathway (IEA)

stem cell differentiation (IEA)

stem cell population maintenance (IEA)

Cellular Component

cytoplasm (IEA)

nucleoplasm (ISO)

nucleus (IBA,IEA)

Molecular Function

DNA-binding transcription activator activity, RNA polymerase II-specific (IEA)

DNA-binding transcription factor activity (IEA)

DNA-binding transcription factor activity, RNA polymerase II-specific (IBA)

protein binding (ISO)

RNA polymerase II cis-regulatory region sequence-specific DNA binding (IBA,IEA)

RNA polymerase II transcription regulatory region sequence-specific DNA binding (IEA)

sequence-specific DNA binding (ISO)

sequence-specific double-stranded DNA binding (ISO)

transcription coactivator activity (IEA)

zinc ion binding (IEA)

References

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

ZIC3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	X	107,822,002 - 107,833,582 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	X	107,821,948 - 107,833,597 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	X	93,648,940 - 93,660,520 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	X	109,807,663 - 109,819,246 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	X	109,807,645 - 109,818,795 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	X	106,941,593 - 106,953,174 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	X	109,131,179 - 109,142,752 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	X	108,775,722 - 108,787,305 (+)	NCBI		UU_Cfam_GSD_1.0

ZIC3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	X	137,566,127 - 137,577,691 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	X	137,566,127 - 137,577,691 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	X	136,648,286 - 136,659,850 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	X	136,476,012 - 136,481,925 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	X	136,373,865 - 136,379,777	NCBI
Celera	X	137,014,356 - 137,020,269 (+)	NCBI		Celera
Cytogenetic Map	X	q26.3	NCBI
HuRef	X	125,916,990 - 125,922,902 (+)	NCBI		HuRef
CHM1_1	X	136,559,744 - 136,565,657 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	X	135,876,075 - 135,887,645 (+)	NCBI		T2T-CHM13v2.0

Zic3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	X	57,075,988 - 57,081,990 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	X	57,068,060 - 57,087,096 (+)	Ensembl		GRCm39 Ensembl
GRCm38	X	58,030,628 - 58,036,630 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	X	58,022,700 - 58,041,736 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	X	55,283,805 - 55,289,807 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	X	54,377,427 - 54,382,686 (+)	NCBI		MGSCv36	mm8
Celera	X	44,504,773 - 44,510,775 (+)	NCBI		Celera
Cytogenetic Map	X	A6	NCBI
cM Map	X	32.56	NCBI

Zic3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	X	141,159,623 - 141,165,587 (+)	NCBI		GRCr8
mRatBN7.2	X	136,123,662 - 136,129,627 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	X	136,124,026 - 136,134,746 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	X	138,319,794 - 138,329,814 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	X	141,857,250 - 141,867,266 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	X	139,427,350 - 139,437,366 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	X	140,875,191 - 140,888,344 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	X	140,878,216 - 140,888,795 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	X	140,918,894 - 140,931,861 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	X	143,128,118 - 143,139,155 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	X	132,262,545 - 132,272,607 (+)	NCBI		Celera
Cytogenetic Map	X	q36	NCBI

Zic3
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955489	7,560,684 - 7,571,892 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955489	7,560,684 - 7,571,739 (-)	NCBI	ChiLan1.0	ChiLan1.0

ZIC3
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	X	136,987,017 - 136,998,644 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	X	136,990,612 - 137,002,244 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	X	126,691,534 - 126,705,788 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	X	136,954,024 - 136,968,240 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	X	136,954,024 - 136,967,819 (+)	Ensembl	panpan1.1		panPan2

Zic3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	X	105,821,756 - 105,833,208 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936513	9,786,709 - 9,793,077 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936513	9,780,895 - 9,792,865 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ZIC3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	X	112,593,301 - 112,604,814 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	X	112,592,951 - 112,605,087 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	X	128,551,482 - 128,563,009 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ZIC3
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	X	112,597,329 - 112,609,411 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	X	112,598,466 - 112,601,803 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666065	50,341,148 - 50,352,637 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Zic3
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624808	9,200,952 - 9,212,093 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624808	9,201,025 - 9,212,192 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in ZIC3
55 total Variants

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

adipose tissue	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	reproductive system	respiratory system
3	3	20	15	7	6	1	6	6	18	12	12	14	1

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_014111986	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038450984	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038450985	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038524458	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038524459	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038588431	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038588432	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038652951	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038652952	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_549291	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000146	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000398	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000110	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000175	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000039	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCAFT00000030141 ⟹ ENSCAFP00000028008

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	X	107,821,948 - 107,827,942 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00000045147 ⟹ ENSCAFP00000042315

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	X	107,821,948 - 107,833,597 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00845052217 ⟹ ENSCAFP00845040956

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	X	109,807,645 - 109,818,795 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00845052226 ⟹ ENSCAFP00845040964

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	X	109,807,645 - 109,813,604 (+)	Ensembl

RefSeq Acc Id:

XM_014111986 ⟹ XP_013967461

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	X	107,822,002 - 107,833,582 (+)	NCBI
Dog10K_Boxer_Tasha	X	93,648,940 - 93,660,520 (+)	NCBI

Sequence:

show sequence

TCTGGAGGCGAAGAGGCTGGGACTCGCGCGGCGAGCGGCGAGGACCGAGCCTGCCTCCAGTCCG
CTGCCTGCCCGCCGGACACGAGCCGGCTCTGCCACGCAGCGCCTCCCAGTCGGAAGGCCGGTGC
CGAGGGAGCCTCCTGGCCCCGCGGTGCTGCACTCTCGGGGAGAGGAGAGGTGCCCGGGACCGGA
TTGGCCAACTCCGCCCTCCACTTATTATTTTGCTTATTTTTCTTTGTGCGCGCCTGTTAGTTTG
TTAAACCAGATCTAGTCTCAGAGTCTTTTCTCCTCCCTTCTCCCCGCTCCTTCTTCCCCCCTCC
TACCCCCTCCTGCTCCACTACTTCCCCTCCTCCCTCCTATCCCTCTGCAGGAGACTCTCAGAGC
GACGGAAAGTTGCAGCCCCTGGCACCGCCTTGGGGGTCTCCCGGCAGTGTCCAACCGCCGCCAC
CCCTCGCCGACTACGGCACTTCGGAGATCTCCTTCGCCCGCACCCTCGCTCAATTCAGCGGTAT
CGCCTGTGCCGAGAACGCCCCACCCATGACGATGCTCCTGGACGGAGGCCCGCAGTTCCCCGGG
CTGGGAGTGGGCAGCTTCGGCGCGCCGCGCCACCACGAGATGCCCAACCGCGAGCCGGCAGGCA
TGGGGCTGAATCCCTTCGGGGACTCGCCCCACGCTGCCGCCGCTGCCGCCGCTGCTGCCTTCAA
GCTGAGCCCTGCCGCGGCTCACGATCTGTCTTCGGGCCAGAGCTCTGCGTTCACGCCGCAGGGC
TCGGGTTACGCCAACGCCCTGGGCCATCATCACCACCACCATCACCACCATCACCACGCCGGCC
AGGTGCCCAGCTACGGCGGTGCCGCCTCCGCCGCCTTCAACTCCACGCGCGACTTTCTGTTCCG
CCAGCGCGGCTCCGGGCTCGGCGAGGCGGCCTCGGGTGGCGGGCAGCACGGGCTCTTCGCCGGC
TCGGCGAGCAGCCTGCACGCTCCGGCTGGCATTCCCGAGCCTCCTGGCTACCTGCTCTTCCCTG
GGCTGCATGAGCAGGGCGCCGGGCACCCGTCGCCCACAGGGCACGTGGACAACAACCAGGTCCA
CCTGGGGCTGCGCGGGGAGCTGTTCGGCCGCGCCGACCCGTACCGCCCCGTGGCCAGCCCGCGC
ACGGACCCCTACACGGCCGGCGCGCAGTTCCCTAACTATAGCCCCATGAACATGAACATGGGCG
TGAACGTGGCGGCGCACCACGGGCCCGGCGCCTTCTTCCGTTATATGCGTCAGCCCATCAAACA
GGAGCTGTCGTGCAAGTGGATCGACGAGGCTCAGCTGAGCCGGCCCAAGAAGAGCTGCGACCGG
ACCTTCAGCACCATGCACGAGTTGGTGACACATGTCACCATGGAGCATGTGGGGGGCCCAGAGC
AGAACAACCACGTCTGCTACTGGGAGGAGTGCCCTCGCGAGGGCAAGTCCTTCAAGGCGAAGTA
CAAACTGGTCAACCACATTCGAGTGCACACGGGCGAGAAACCCTTCCCCTGCCCCTTCCCGGGC
TGCGGAAAGATCTTTGCCCGCTCCGAGAACCTCAAGATCCACAAGAGGACCCACACAGGTGAGA
AACCTTTCAAATGTGAATTCGAAGGTTGCGATAGACGCTTTGCCAACAGCAGCGACCGCAAGAA
GCACATGCACGTGCACACCTCGGACAAGCCCTATATCTGCAAAGTGTGCGACAAGTCCTACACG
CACCCGAGCTCCCTGCGCAAGCACATGAAGTGTTGTCCTGCTTGGTATCCGGGACAGACTCTAA
TTCCTGATGAAGAACTTGATACTGACGTTGGTATGCAGCAGCCAGCCCTCCATAACACTACCTA
TACTAAATGCAGGGTTAATGCCGAGCCTACTGTGCAAGAAATGATTTACTGATGAGGTTTCAAA
GAAAACCACATCAATTTGGATGTCTGTTACCTTGAAGTGATCATTTTAAGAGTAGTAGCTTCTT
CCCTAGGTATAAAAAGACTATTTTCTTCTTTTGGTGTATTTCAGTCTGTGTTGAGCAATCATTT
GTGAAATGAAAAAGCAAAAAAGCTCCCACCCCCTCCCATGCCCTTCCCTCACATTTTGCCACTT
TAGGATTATAAGTGAGAAGATGGAGGTGAAGACTGGCCTAATTCATAACCCAGTGTGTATTATC
TCATGCATTGTGTTGACCTTGTTGAAAATCTCTTTCAAATATCTGCATTCCACATGTAGAGTTC
ATGTGTTTAAGACTAGAAACACAAATGCTTGTTTTGTTAATTTTGTATGTTTGTGTTCAAAAAG
CAGTACCCAGGATCCCTACAATTGTTGTTTGACTTAAATAAAACCATTAAAAAATTT

hide sequence

RefSeq Acc Id:

XM_038450984 ⟹ XP_038306912

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	X	109,807,663 - 109,813,581 (+)	NCBI

RefSeq Acc Id:

XM_038450985 ⟹ XP_038306913

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	X	109,807,663 - 109,819,246 (+)	NCBI

RefSeq Acc Id:

XM_038524458 ⟹ XP_038380386

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	X	106,941,593 - 106,947,511 (+)	NCBI

RefSeq Acc Id:

XM_038524459 ⟹ XP_038380387

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	X	106,941,593 - 106,953,174 (+)	NCBI

RefSeq Acc Id:

XM_038588431 ⟹ XP_038444359

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	X	108,775,722 - 108,781,641 (+)	NCBI

RefSeq Acc Id:

XM_038588432 ⟹ XP_038444360

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	X	108,775,722 - 108,787,305 (+)	NCBI

RefSeq Acc Id:

XM_038652951 ⟹ XP_038508879

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	X	109,131,179 - 109,137,096 (+)	NCBI

RefSeq Acc Id:

XM_038652952 ⟹ XP_038508880

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	X	109,131,179 - 109,142,752 (+)	NCBI

RefSeq Acc Id:

XM_549291 ⟹ XP_549291

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	X	107,822,002 - 107,827,508 (+)	NCBI
Dog10K_Boxer_Tasha	X	93,648,940 - 93,654,858 (+)	NCBI

Sequence:

show sequence

TCTGGAGGCGAAGAGGCTGGGACTCGCGCGGCGAGCGGCGAGGACCGAGCCTGCCTCCAGTCCG
CTGCCTGCCCGCCGGACACGAGCCGGCTCTGCCACGCAGCGCCTCCCAGTCGGAAGGCCGGTGC
CGAGGGAGCCTCCTGGCCCCGCGGTGCTGCACTCTCGGGGAGAGGAGAGGTGCCCGGGACCGGA
TTGGCCAACTCCGCCCTCCACTTATTATTTTGCTTATTTTTCTTTGTGCGCGCCTGTTAGTTTG
TTAAACCAGATCTAGTCTCAGAGTCTTTTCTCCTCCCTTCTCCCCGCTCCTTCTTCCCCCCTCC
TACCCCCTCCTGCTCCACTACTTCCCCTCCTCCCTCCTATCCCTCTGCAGGAGACTCTCAGAGC
GACGGAAAGTTGCAGCCCCTGGCACCGCCTTGGGGGTCTCCCGGCAGTGTCCAACCGCCGCCAC
CCCTCGCCGACTACGGCACTTCGGAGATCTCCTTCGCCCGCACCCTCGCTCAATTCAGCGGTAT
CGCCTGTGCCGAGAACGCCCCACCCATGACGATGCTCCTGGACGGAGGCCCGCAGTTCCCCGGG
CTGGGAGTGGGCAGCTTCGGCGCGCCGCGCCACCACGAGATGCCCAACCGCGAGCCGGCAGGCA
TGGGGCTGAATCCCTTCGGGGACTCGCCCCACGCTGCCGCCGCTGCCGCCGCTGCTGCCTTCAA
GCTGAGCCCTGCCGCGGCTCACGATCTGTCTTCGGGCCAGAGCTCTGCGTTCACGCCGCAGGGC
TCGGGTTACGCCAACGCCCTGGGCCATCATCACCACCACCATCACCACCATCACCACGCCGGCC
AGGTGCCCAGCTACGGCGGTGCCGCCTCCGCCGCCTTCAACTCCACGCGCGACTTTCTGTTCCG
CCAGCGCGGCTCCGGGCTCGGCGAGGCGGCCTCGGGTGGCGGGCAGCACGGGCTCTTCGCCGGC
TCGGCGAGCAGCCTGCACGCTCCGGCTGGCATTCCCGAGCCTCCTGGCTACCTGCTCTTCCCTG
GGCTGCATGAGCAGGGCGCCGGGCACCCGTCGCCCACAGGGCACGTGGACAACAACCAGGTCCA
CCTGGGGCTGCGCGGGGAGCTGTTCGGCCGCGCCGACCCGTACCGCCCCGTGGCCAGCCCGCGC
ACGGACCCCTACACGGCCGGCGCGCAGTTCCCTAACTATAGCCCCATGAACATGAACATGGGCG
TGAACGTGGCGGCGCACCACGGGCCCGGCGCCTTCTTCCGTTATATGCGTCAGCCCATCAAACA
GGAGCTGTCGTGCAAGTGGATCGACGAGGCTCAGCTGAGCCGGCCCAAGAAGAGCTGCGACCGG
ACCTTCAGCACCATGCACGAGTTGGTGACACATGTCACCATGGAGCATGTGGGGGGCCCAGAGC
AGAACAACCACGTCTGCTACTGGGAGGAGTGCCCTCGCGAGGGCAAGTCCTTCAAGGCGAAGTA
CAAACTGGTCAACCACATTCGAGTGCACACGGGCGAGAAACCCTTCCCCTGCCCCTTCCCGGGC
TGCGGAAAGATCTTTGCCCGCTCCGAGAACCTCAAGATCCACAAGAGGACCCACACAGGTGAGA
AACCTTTCAAATGTGAATTCGAAGGTTGCGATAGACGCTTTGCCAACAGCAGCGACCGCAAGAA
GCACATGCACGTGCACACCTCGGACAAGCCCTATATCTGCAAAGTGTGCGACAAGTCCTACACG
CACCCGAGCTCCCTGCGCAAGCACATGAAGGTTCATGAATCTCAAGGGTCAGATTCCTCCCCTG
CTGCCAGTTCAGGCTATGAATCTTCCACTCCACCCGCTATAGCTTCTGCAAACAGTAAAGATAC
CACTAAAACCCCTTCTGCAGTTCAAACTAGCACCAGCCACAACCCTGGACTTCCTCCCAATTTT
AACGAATGGTACGTCTGAGGACAAACACAAACACAAACCCTGTTAACTATAGAATGGACCAAAT
GCATTTTTAAAAGGAAACTGAGACCAATCAGATGGAAATGGAGTTTTTTTTTTAAGGCAAGAGG
CTATATATAGGGTTACATCATGGTAATTGCAATTGTCCAGGAAGGTTTTGGGGCAAGATCCAAA
AGTAGCCATGCCCTTTTCTCAGGATTAGAAAATATGTTTTGGCATTTGAAGGATTTTCAAAAAA
ATCTTTTCACTGCTTTTTCCTCCCTTTTCTCTTGCTCTCTGCACACCCCATTCCTAAACTCCTT
CAGCTCATTTTAACACTTGTCCTGTTTCTTGAGAGGAAGTTATAGAAGGCTTGGTGGTGGTGGT
GATGTTAAACTGATGGAAATTCTTCGCCTTTAGTGGTGATTGTTTAAACTCTCACAGTCTTAAA
CCGTGCCAAAGTCCTGTTATGTCTTGAACTTTGCCTCAAAGCATTACACTTGTGAATGTATTTT
TGTCTAATGGGGTCGAAACTGTTGTTCAGTATTTTTTCAGGCTGAGGATGTGATGTTACTCTAC
ACAGATTGTGACGTTTAGTATACAGTTGCCTTTTGTAATAACTTTTTTTTTGTAAATACATATC
CATTGATGCCATATTTATCGTTTGTAATTTAATTATTGCTACAAGTGCCGGGAACTGAACAATA
TTTATGGAAAAAATGTTTTCTAACAAATGCTGTACAGCTTTTGATTATAACTGCTTTAGCATTA
AATTTTATTGTTTTGAAAGAAGAACACAATTTACAGTTTTTGAACCACTGACTCCTTTCTCTTG
TTTTGTAACAGCCTCCTTCTACAAAGAGGAGACGTAAGCAAATGAAATCTTGTTTGTTGGTATT
TATAACTCAGATCCCTTTTTTAATTGTTAAATTATTTTTCTATTGCAGCGTAGACTCCTTACAG
TGTCAGTTTCCATCTGGGGAGACCCTCCTTTCTTTATCTGTAGCTCAGATGGTTGTTTAACTGC
GAGTTTAAATGTTTGTCCTGGATTTTCGGCATGCAAATCAAATATTACTGATCAGTTCAGTTAG
TGGCCATGACATCTCAATCTTGTATTTCAAAGACTGAGAAGCTGGATTTAATCATCCCTGCCCT
ACATATATAAAGATAAGGTAACCTAATGAGTCTTATGTCCTTTAGTTTTTTCTATTACCTTACA
TAAAAATGAACATTGCAGCAGGATGCATGTCTGTGTATTCTATCGAGAGATCACCCATATACAT
ATATATGTTTGTATCTATGACTTATCTAATCTGCCTATCAAATCTATCTAGCTATCTATATATT
TTCAAAAGTAAGCGTATGTCTGAAACAGTGGTGATGAGTAAGGCCAGTCGAGCCGTGCTTATGG
TTAAAGTGCTTCTTAAAAGAACCATAGTCCATTTACAATTTTGGAAGGCAAAGGCTGATTTGTT
TTGCTGTATATAGTTCAATTCATAATTATCACAGTTATTCATAACATTTTTATAGCGGTGTAAT
AACTGCAGCGGTTCTGAAATGATATTATGGAAAGAAAAACATTTGCAAAATATGTATTTTTAAA
GTTCATGGTTTGTAGGCAAAGATGTTAAGAGCATTGTTTCCATTAAAATCAATAACAATGAAAA
A

hide sequence

Protein Sequences


Protein RefSeqs	XP_013967461	(Get FASTA)	NCBI Sequence Viewer
	XP_038306912	(Get FASTA)	NCBI Sequence Viewer
	XP_038306913	(Get FASTA)	NCBI Sequence Viewer
	XP_038380386	(Get FASTA)	NCBI Sequence Viewer
	XP_038380387	(Get FASTA)	NCBI Sequence Viewer
	XP_038444359	(Get FASTA)	NCBI Sequence Viewer
	XP_038444360	(Get FASTA)	NCBI Sequence Viewer
	XP_038508879	(Get FASTA)	NCBI Sequence Viewer
	XP_038508880	(Get FASTA)	NCBI Sequence Viewer
	XP_549291	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000028008.4
	ENSCAFP00000042315.2
	ENSCAFP00040015413.1
	ENSCAFP00040015462.1
	ENSCAFP00845040956
	ENSCAFP00845040956.1
	ENSCAFP00845040964
	ENSCAFP00845040964.1

RefSeq Acc Id:	XP_013967461 ⟸ XM_014111986
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I3S767 (UniProtKB/TrEMBL), A0A8P0SVT0 (UniProtKB/TrEMBL), A0A8C0S3U3 (UniProtKB/TrEMBL)
- Sequence:	show sequence MTMLLDGGPQFPGLGVGSFGAPRHHEMPNREPAGMGLNPFGDSPHAAAAAAAAAFKLSPAAAHD LSSGQSSAFTPQGSGYANALGHHHHHHHHHHHAGQVPSYGGAASAAFNSTRDFLFRQRGSGLGE AASGGGQHGLFAGSASSLHAPAGIPEPPGYLLFPGLHEQGAGHPSPTGHVDNNQVHLGLRGELF GRADPYRPVASPRTDPYTAGAQFPNYSPMNMNMGVNVAAHHGPGAFFRYMRQPIKQELSCKWID EAQLSRPKKSCDRTFSTMHELVTHVTMEHVGGPEQNNHVCYWEECPREGKSFKAKYKLVNHIRV HTGEKPFPCPFPGCGKIFARSENLKIHKRTHTGEKPFKCEFEGCDRRFANSSDRKKHMHVHTSD KPYICKVCDKSYTHPSSLRKHMKCCPAWYPGQTLIPDEELDTDVGMQQPALHNTTYTKCRVNAE PTVQEMIY hide sequence

RefSeq Acc Id:	XP_549291 ⟸ XM_549291
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C0LL39 (UniProtKB/TrEMBL), A0A8I3Q6K6 (UniProtKB/TrEMBL), A0A8P0SMN0 (UniProtKB/TrEMBL), A0A8C0S3R6 (UniProtKB/TrEMBL)
- Sequence:	show sequence MTMLLDGGPQFPGLGVGSFGAPRHHEMPNREPAGMGLNPFGDSPHAAAAAAAAAFKLSPAAAHD LSSGQSSAFTPQGSGYANALGHHHHHHHHHHHAGQVPSYGGAASAAFNSTRDFLFRQRGSGLGE AASGGGQHGLFAGSASSLHAPAGIPEPPGYLLFPGLHEQGAGHPSPTGHVDNNQVHLGLRGELF GRADPYRPVASPRTDPYTAGAQFPNYSPMNMNMGVNVAAHHGPGAFFRYMRQPIKQELSCKWID EAQLSRPKKSCDRTFSTMHELVTHVTMEHVGGPEQNNHVCYWEECPREGKSFKAKYKLVNHIRV HTGEKPFPCPFPGCGKIFARSENLKIHKRTHTGEKPFKCEFEGCDRRFANSSDRKKHMHVHTSD KPYICKVCDKSYTHPSSLRKHMKVHESQGSDSSPAASSGYESSTPPAIASANSKDTTKTPSAVQ TSTSHNPGLPPNFNEWYV hide sequence

Ensembl Acc Id:

ENSCAFP00000042315 ⟸ ENSCAFT00000045147

Ensembl Acc Id:

ENSCAFP00000028008 ⟸ ENSCAFT00000030141

RefSeq Acc Id:	XP_038380387 ⟸ XM_038524459
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038380386 ⟸ XM_038524458
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038508880 ⟸ XM_038652952
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038508879 ⟸ XM_038652951
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038306913 ⟸ XM_038450985
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I3S767 (UniProtKB/TrEMBL), A0A8P0SVT0 (UniProtKB/TrEMBL), A0A8C0S3U3 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038306912 ⟸ XM_038450984
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C0LL39 (UniProtKB/TrEMBL), A0A8I3Q6K6 (UniProtKB/TrEMBL), A0A8P0SMN0 (UniProtKB/TrEMBL), A0A8C0S3R6 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038444360 ⟸ XM_038588432
- Peptide Label:	isoform X2
- UniProtKB:	A0A8C0S3U3 (UniProtKB/TrEMBL), A0A8I3S767 (UniProtKB/TrEMBL), A0A8P0SVT0 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038444359 ⟸ XM_038588431
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C0LL39 (UniProtKB/TrEMBL), A0A8C0S3R6 (UniProtKB/TrEMBL), A0A8I3Q6K6 (UniProtKB/TrEMBL), A0A8P0SMN0 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSCAFP00845040956 ⟸ ENSCAFT00845052217

Ensembl Acc Id:

ENSCAFP00845040964 ⟸ ENSCAFT00845052226

Protein Domains

C2H2-type

Promoters

RGD ID:

13689443

Promoter ID:

EPDNEW_C7511

Type:

single initiation site

Name:

ZIC3_1

Description:

Zic family member 3

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	X	107,822,592 - 107,822,652	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000018979	Ensembl, UniProtKB/TrEMBL
	ENSCAFG00040009558	UniProtKB/TrEMBL
	ENSCAFG00845029495	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000030141.6	UniProtKB/TrEMBL
	ENSCAFT00000045147.4	UniProtKB/TrEMBL
	ENSCAFT00040017762.1	UniProtKB/TrEMBL
	ENSCAFT00040017814.1	UniProtKB/TrEMBL
	ENSCAFT00845052217	ENTREZGENE
	ENSCAFT00845052217.1	UniProtKB/TrEMBL
	ENSCAFT00845052226	ENTREZGENE
	ENSCAFT00845052226.1	UniProtKB/TrEMBL
Gene3D-CATH	Classic Zinc Finger	UniProtKB/TrEMBL
InterPro	GLI_C2H2-zinc-finger	UniProtKB/TrEMBL
	Znf_C2H2_sf	UniProtKB/TrEMBL
	Znf_C2H2_type	UniProtKB/TrEMBL
	Znf_ZIC	UniProtKB/TrEMBL
NCBI Gene	ZIC3	ENTREZGENE
PANTHER	ZINC FINGER PROTEIN ZIC 3	UniProtKB/TrEMBL
	ZINC FINGER PROTEIN ZIC AND GLI	UniProtKB/TrEMBL
Pfam	zf-C2H2	UniProtKB/TrEMBL
	zf_ZIC	UniProtKB/TrEMBL
PROSITE	ZINC_FINGER_C2H2_1	UniProtKB/TrEMBL
	ZINC_FINGER_C2H2_2	UniProtKB/TrEMBL
SMART	ZnF_C2H2	UniProtKB/TrEMBL
Superfamily-SCOP	SSF57667	UniProtKB/TrEMBL
UniProt	A0A8C0LL39	ENTREZGENE
	A0A8C0S3R6	ENTREZGENE, UniProtKB/TrEMBL
	A0A8C0S3U3	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3Q6K6	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3S767	ENTREZGENE, UniProtKB/TrEMBL
	A0A8P0SMN0	ENTREZGENE, UniProtKB/TrEMBL
	A0A8P0SVT0	ENTREZGENE, UniProtKB/TrEMBL
VGNC ID	VGNC:48634	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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