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Gene: NELFE (negative elongation factor complex member E) Canis lupus familiaris

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Symbol:

NELFE

Name:

negative elongation factor complex member E

RGD ID:

12215536

Description:

ENCODES a protein that exhibits chromatin binding (ortholog); INVOLVED IN negative regulation of transcription by RNA polymerase II (ortholog); negative regulation of transcription elongation by RNA polymerase II (ortholog); positive regulation of ERK1 and ERK2 cascade (ortholog); PARTICIPATES IN RNA polymerase II transcription elongation pathway; ASSOCIATED WITH proteasome-associated autoinflammatory syndrome 1 (ortholog); trichohepatoenteric syndrome (ortholog); FOUND IN chromatin (ortholog); nucleus (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

negative elongation factor E; RD RNA binding protein; RDBP

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	12	1,406,411 - 1,412,387 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	12	1,406,271 - 1,412,324 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	12	1,541,468 - 1,547,598 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	12	1,548,568 - 1,554,700 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	12	1,548,568 - 1,554,605 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	12	1,405,843 - 1,411,974 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	12	1,474,213 - 1,480,345 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	12	1,539,542 - 1,546,943 (-)	NCBI		UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

proteasome-associated autoinflammatory syndrome 1 (ISO)

trichohepatoenteric syndrome (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

negative regulation of transcription by RNA polymerase II (ISO)

negative regulation of transcription elongation by RNA polymerase II (IBA,IEA,ISO)

positive regulation of ERK1 and ERK2 cascade (ISO)

positive regulation of protein modification process (ISO)

positive regulation of transcription by RNA polymerase II (ISO)

regulation of DNA-templated transcription (IEA)

Cellular Component

chromatin (IEA,ISO)

chromosome (IEA)

NELF complex (IBA,IEA)

nuclear body (IEA)

nucleoplasm (IEA)

nucleus (IEA,ISO)

plasma membrane (IEA)

Molecular Function

chromatin binding (IEA,ISO)

mRNA binding (IEA)

protein binding (ISO)

RNA binding (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

RNA polymerase II transcription elongation pathway (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

NELFE
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	12	1,406,411 - 1,412,387 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	12	1,406,271 - 1,412,324 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	12	1,541,468 - 1,547,598 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	12	1,548,568 - 1,554,700 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	12	1,548,568 - 1,554,605 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	12	1,405,843 - 1,411,974 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	12	1,474,213 - 1,480,345 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	12	1,539,542 - 1,546,943 (-)	NCBI		UU_Cfam_GSD_1.0

NELFE
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	6	31,952,087 - 31,958,971 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	6	31,952,087 - 31,959,038 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	6	31,919,864 - 31,926,748 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	6	32,027,843 - 32,034,843 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	6	32,027,843 - 32,034,747	NCBI
Celera	6	33,519,627 - 33,526,530 (-)	NCBI		Celera
Cytogenetic Map	6	p21.33	NCBI
HuRef	6	31,706,833 - 31,713,834 (-)	NCBI		HuRef
CHM1_1	6	31,921,945 - 31,928,945 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	6	31,805,292 - 31,812,176 (-)	NCBI		T2T-CHM13v2.0

Nelfe
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	17	35,069,367 - 35,075,348 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	17	35,069,367 - 35,075,348 (+)	Ensembl		GRCm39 Ensembl
GRCm38	17	34,850,391 - 34,856,372 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	17	34,850,391 - 34,856,372 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	17	34,987,336 - 34,993,317 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	17	34,458,975 - 34,464,214 (+)	NCBI		MGSCv36	mm8
Celera	17	37,945,699 - 37,951,680 (+)	NCBI		Celera
Cytogenetic Map	17	B1	NCBI
cM Map	17	18.4	NCBI

Nelfe
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	20	3,981,259 - 3,987,016 (-)	NCBI		GRCr8
mRatBN7.2	20	3,976,512 - 3,982,389 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	20	3,976,518 - 3,982,355 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	20	4,676,633 - 4,682,383 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	20	4,038,381 - 4,044,131 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	20	4,575,547 - 4,581,290 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	20	4,530,328 - 4,536,085 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	20	4,530,342 - 4,536,209 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	20	6,610,127 - 6,615,884 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	20	4,077,925 - 4,081,561 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	20	4,078,021 - 4,081,787 (-)	NCBI
Celera	20	4,048,306 - 4,054,061 (+)	NCBI		Celera
Cytogenetic Map	20	p12	NCBI

Nelfe
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955437	466,690 - 473,084 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955437	467,018 - 473,084 (-)	NCBI	ChiLan1.0	ChiLan1.0

NELFE
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	5	46,428,781 - 46,435,590 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	6	42,390,268 - 42,397,077 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	6	31,612,924 - 31,619,732 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	6	32,499,538 - 32,506,382 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	6	32,499,540 - 32,506,382 (-)	Ensembl	panpan1.1		panPan2

Nelfe
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404946	35,965,333 - 35,971,346 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936727	1,589,942 - 1,598,182 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936727	1,589,942 - 1,596,009 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

NELFE
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	7	24,040,525 - 24,047,025 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	7	24,040,525 - 24,046,932 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	7	27,765,281 - 27,771,676 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

NELFE
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	17	40,063,298 - 40,069,714 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	17	40,063,755 - 40,198,451 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666044	31,868,805 - 31,875,524 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Nelfe
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624754	24,300,602 - 24,310,671 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624754	24,300,012 - 24,310,777 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in NELFE
84 total Variants

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

adipose tissue	alimentary part of gastrointestinal system	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	reproductive system	respiratory system
6	5	5	23	22	16	6	6	6	6	33	22	12	14	10

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005627169	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_022425860	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038491394	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038553608	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038553609	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038553610	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038617484	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038617485	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038617486	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038678708	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038683069	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038683070	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038683071	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_532087	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000012	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000123	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000012	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000357	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000012	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCAFT00000001076 ⟹ ENSCAFP00000000986

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	12	1,406,412 - 1,412,040 (-)	Ensembl

Ensembl Acc Id:

ENSCAFT00000072412 ⟹ ENSCAFP00000056410

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	12	1,406,271 - 1,412,324 (-)	Ensembl

Ensembl Acc Id:

ENSCAFT00845024782 ⟹ ENSCAFP00845019493

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	12	1,548,568 - 1,554,605 (-)	Ensembl

Ensembl Acc Id:

ENSCAFT00845024793 ⟹ ENSCAFP00845019501

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	12	1,548,568 - 1,554,340 (-)	Ensembl

Ensembl Acc Id:

ENSCAFT00845024806 ⟹ ENSCAFP00845019513

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	12	1,548,568 - 1,552,835 (-)	Ensembl

RefSeq Acc Id:

XM_005627169 ⟹ XP_005627226

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	12	1,406,411 - 1,412,318 (-)	NCBI
Dog10K_Boxer_Tasha	12	1,541,468 - 1,547,559 (-)	NCBI

Sequence:

show sequence

CGCTGTGAGCCCGCTCGCCGCCGCCAGCGCGGGCGCCGCCCGAGACCGTGGGCCCCCGGTTACC
GCCCCCTCAGAGCGCTGGTGGCCGTGATTGCCGGAGAGGAGAGGGAGTGCTGGTTGGTCCGCAC
GAGCGGGGGTTTGGACGGCAGCCTCGTTGAAGCAAGGGGTAGGGAGAGGCAAAAGACAGGAGTA
GGAGCCACCATGTTGGTGATACCCCCCGGACTGAGCGAGGAGGAGGAGGCTCTGCAGAAGAAAT
TCAACAAACTCAAGAAAAAGAAAAAGGCATTGCTGGCTCTGAAGAAGCAAAGTAGTAGCAGCAC
AGCCAGCCAAGGCGGTGTGAAACGCTCACTGTCGGAACAGCCTGTGGTGGACACAGCCACGGCA
ACAGAGCAGGCAAAGCAGCTAGTGAAGTCAGGAGCCATCAGTGCCATCAAGGCTGAGACCAAGA
ACTCAGGCTTCAAGCGTTCTCGAACCCTAGAGGGGAAGTTAAAGGACCCTGAGAAGGGGCCAGT
TCCCACTTTCCAGCCGTTCCAAAGAAGCATATCTGCCGATGATGATCTGCAGGAGTCGTCCAGA
CGCCCCCAAAGGAAATCTCTGTATGAGAGTTTTGTGTCTTCCAGTGATCGGCTTCGGGAACTGG
GGCCAGATGGGGAGGAGGCAGAGGGCCCAGGGGCTGGTGATGGTCCCCCTCGAAGCTTTGACTG
GGGCTATGAAGAACGTGGTGGTGCCCGCTCCTCAACCTCCCCCCCACGAAGCCGCAGCCGGGAC
CACAGTCGTGAGCGGAACCGGGACAGAGACCGTGATCGAGAACGGGATCGAGACCGTGATCGGG
ACAGGGACCGCGATCGGGACAGGGACCGCGATCGGGACAGGGACCGTGATCGGGACAGGGACCG
CGATCGAGAACGAGAGGGCCCTTTCCGCAGGTCGGATTCATTCCCTGAACGCAGGGCCCCTCGG
AAGGGTAATACTCTCTATGTGTATGGAGAGGACATGACGCCCACCCTCCTTCGTGGGGCCTTCT
CTCCCTTTGGAAACATCATTGACCTCTCCATGGACCCACCCAGAAACTGTGCCTTCGTCACCTA
TGAAAAGATGGAGTCAGCAGATCAGGCCGTTGCTGAGCTCAATGGGACCCAGGTGGAGTCTGTA
CAGCTCAAAGTCAGCATTGCCCGCAAGCAGCCCATGCTGGACGCTGCCACTGGCAAGTCTGTCT
GGGGCTCTCTCGCTGTCCAGAATAGCCCTAAGGGTTGCCATCGGGACAAGAGGACCCAGATTGT
CTACAGCGATGATGTCTACAAGGAAAACCTTGTGGATGGCTTCTAGGGAATGGAGCTGTATTCC
GTGTGCCTCATCTGCGCCAACACTTGGTCTCAGTAAAACACTGAGGTGGAAGCTCA

hide sequence

RefSeq Acc Id:

XM_038491394 ⟹ XP_038347322

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	12	1,405,843 - 1,411,974 (-)	NCBI

RefSeq Acc Id:

XM_038553608 ⟹ XP_038409536

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	12	1,539,542 - 1,546,943 (-)	NCBI

RefSeq Acc Id:

XM_038553609 ⟹ XP_038409537

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	12	1,539,542 - 1,546,913 (-)	NCBI

RefSeq Acc Id:

XM_038553610 ⟹ XP_038409538

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	12	1,539,542 - 1,546,913 (-)	NCBI

RefSeq Acc Id:

XM_038617484 ⟹ XP_038473412

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	12	1,474,213 - 1,480,345 (-)	NCBI

RefSeq Acc Id:

XM_038617485 ⟹ XP_038473413

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	12	1,474,213 - 1,480,307 (-)	NCBI

RefSeq Acc Id:

XM_038617486 ⟹ XP_038473414

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	12	1,474,213 - 1,480,180 (-)	NCBI

RefSeq Acc Id:

XM_038678708 ⟹ XP_038534636

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
Dog10K_Boxer_Tasha	12	1,541,468 - 1,547,432 (-)	NCBI

RefSeq Acc Id:

XM_038683069 ⟹ XP_038538997

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	12	1,548,568 - 1,554,700 (-)	NCBI

RefSeq Acc Id:

XM_038683070 ⟹ XP_038538998

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	12	1,548,568 - 1,554,661 (-)	NCBI

RefSeq Acc Id:

XM_038683071 ⟹ XP_038538999

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	12	1,548,568 - 1,554,535 (-)	NCBI

RefSeq Acc Id:

XM_532087 ⟹ XP_532087

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	12	1,406,411 - 1,412,387 (-)	NCBI
Dog10K_Boxer_Tasha	12	1,541,468 - 1,547,598 (-)	NCBI

Sequence:

show sequence

GACTGCCGGGCGGAAGTGTGTAGCCTCGGGCCGCCTTGGTTACCGCGTTCCCCGCCCCTCGTAC
GTCATCGCTGTGAGCCCGCTCGCCGCCGCCAGCGCGGGCGCCGCCCGAGACCGTGGGCCCCCGG
TTACCGCCCCCTCAGGAGCCACCATGTTGGTGATACCCCCCGGACTGAGCGAGGAGGAGGAGGC
TCTGCAGAAGAAATTCAACAAACTCAAGAAAAAGAAAAAGGCATTGCTGGCTCTGAAGAAGCAA
AGTAGTAGCAGCACAGCCAGCCAAGGCGGTGTGAAACGCTCACTGTCGGAACAGCCTGTGGTGG
ACACAGCCACGGCAACAGAGCAGGCAAAGCAGCTAGTGAAGTCAGGAGCCATCAGTGCCATCAA
GGCTGAGACCAAGAACTCAGGCTTCAAGCGTTCTCGAACCCTAGAGGGGAAGTTAAAGGACCCT
GAGAAGGGGCCAGTTCCCACTTTCCAGCCGTTCCAAAGAAGCATATCTGCCGATGATGATCTGC
AGGAGTCGTCCAGACGCCCCCAAAGGAAATCTCTGTATGAGAGTTTTGTGTCTTCCAGTGATCG
GCTTCGGGAACTGGGGCCAGATGGGGAGGAGGCAGAGGGCCCAGGGGCTGGTGATGGTCCCCCT
CGAAGCTTTGACTGGGGCTATGAAGAACGTGGTGGTGCCCGCTCCTCAACCTCCCCCCCACGAA
GCCGCAGCCGGGACCACAGTCGTGAGCGGAACCGGGACAGAGACCGTGATCGAGAACGGGATCG
AGACCGTGATCGGGACAGGGACCGCGATCGGGACAGGGACCGCGATCGGGACAGGGACCGTGAT
CGGGACAGGGACCGCGATCGAGAACGAGAGGGCCCTTTCCGCAGGTCGGATTCATTCCCTGAAC
GCAGGGCCCCTCGGAAGGGTAATACTCTCTATGTGTATGGAGAGGACATGACGCCCACCCTCCT
TCGTGGGGCCTTCTCTCCCTTTGGAAACATCATTGACCTCTCCATGGACCCACCCAGAAACTGT
GCCTTCGTCACCTATGAAAAGATGGAGTCAGCAGATCAGGCCGTTGCTGAGCTCAATGGGACCC
AGGTGGAGTCTGTACAGCTCAAAGTCAGCATTGCCCGCAAGCAGCCCATGCTGGACGCTGCCAC
TGGCAAGTCTGTCTGGGGCTCTCTCGCTGTCCAGAATAGCCCTAAGGGTTGCCATCGGGACAAG
AGGACCCAGATTGTCTACAGCGATGATGTCTACAAGGAAAACCTTGTGGATGGCTTCTAGGGAA
TGGAGCTGTATTCCGTGTGCCTCATCTGCGCCAACACTTGGTCTCAGTAAAACACTGAGGTGGA
AGCTCA

hide sequence

Protein Sequences


Protein RefSeqs	XP_005627226	(Get FASTA)	NCBI Sequence Viewer
	XP_038347322	(Get FASTA)	NCBI Sequence Viewer
	XP_038409536	(Get FASTA)	NCBI Sequence Viewer
	XP_038409537	(Get FASTA)	NCBI Sequence Viewer
	XP_038409538	(Get FASTA)	NCBI Sequence Viewer
	XP_038473412	(Get FASTA)	NCBI Sequence Viewer
	XP_038473413	(Get FASTA)	NCBI Sequence Viewer
	XP_038473414	(Get FASTA)	NCBI Sequence Viewer
	XP_038534636	(Get FASTA)	NCBI Sequence Viewer
	XP_038538997	(Get FASTA)	NCBI Sequence Viewer
	XP_038538998	(Get FASTA)	NCBI Sequence Viewer
	XP_038538999	(Get FASTA)	NCBI Sequence Viewer
	XP_532087	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000000986.4
	ENSCAFP00000056410.2
	ENSCAFP00030037811.1
	ENSCAFP00845019493
	ENSCAFP00845019493.1
	ENSCAFP00845019501
	ENSCAFP00845019501.1
	ENSCAFP00845019513.1

RefSeq Acc Id:

XP_532087 ⟸ XM_532087

- UniProtKB:

A0A8C0JHL7 (UniProtKB/TrEMBL), A0A8I3NRP4 (UniProtKB/TrEMBL), A0A8P0T8L2 (UniProtKB/TrEMBL), A0A8C0PNU3 (UniProtKB/TrEMBL), A0A8I3NSF7 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MLVIPPGLSEEEEALQKKFNKLKKKKKALLALKKQSSSSTASQGGVKRSLSEQPVVDTATATEQ
AKQLVKSGAISAIKAETKNSGFKRSRTLEGKLKDPEKGPVPTFQPFQRSISADDDLQESSRRPQ
RKSLYESFVSSSDRLRELGPDGEEAEGPGAGDGPPRSFDWGYEERGGARSSTSPPRSRSRDHSR
ERNRDRDRDRERDRDRDRDRDRDRDRDRDRDRDRDRDRDRDREREGPFRRSDSFPERRAPRKGN
TLYVYGEDMTPTLLRGAFSPFGNIIDLSMDPPRNCAFVTYEKMESADQAVAELNGTQVESVQLK
VSIARKQPMLDAATGKSVWGSLAVQNSPKGCHRDKRTQIVYSDDVYKENLVDGF

hide sequence

RefSeq Acc Id:

XP_005627226 ⟸ XM_005627169

- UniProtKB:

A0A8C0JHL7 (UniProtKB/TrEMBL), A0A8I3NRP4 (UniProtKB/TrEMBL), A0A8P0T8L2 (UniProtKB/TrEMBL), A0A8C0PNU3 (UniProtKB/TrEMBL), A0A8I3NSF7 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MLVIPPGLSEEEEALQKKFNKLKKKKKALLALKKQSSSSTASQGGVKRSLSEQPVVDTATATEQ
AKQLVKSGAISAIKAETKNSGFKRSRTLEGKLKDPEKGPVPTFQPFQRSISADDDLQESSRRPQ
RKSLYESFVSSSDRLRELGPDGEEAEGPGAGDGPPRSFDWGYEERGGARSSTSPPRSRSRDHSR
ERNRDRDRDRERDRDRDRDRDRDRDRDRDRDRDRDRDRDRDREREGPFRRSDSFPERRAPRKGN
TLYVYGEDMTPTLLRGAFSPFGNIIDLSMDPPRNCAFVTYEKMESADQAVAELNGTQVESVQLK
VSIARKQPMLDAATGKSVWGSLAVQNSPKGCHRDKRTQIVYSDDVYKENLVDGF

hide sequence

Ensembl Acc Id:

ENSCAFP00000000986 ⟸ ENSCAFT00000001076

Ensembl Acc Id:

ENSCAFP00000056410 ⟸ ENSCAFT00000072412

RefSeq Acc Id:

XP_038347322 ⟸ XM_038491394

RefSeq Acc Id:

XP_038473412 ⟸ XM_038617484

RefSeq Acc Id:

XP_038473413 ⟸ XM_038617485

RefSeq Acc Id:

XP_038473414 ⟸ XM_038617486

RefSeq Acc Id:	XP_038538997 ⟸ XM_038683069
- UniProtKB:	A0A8C0JHL7 (UniProtKB/TrEMBL), A0A8I3NRP4 (UniProtKB/TrEMBL), A0A8P0T8L2 (UniProtKB/TrEMBL), A0A8C0PNU3 (UniProtKB/TrEMBL), A0A8I3NSF7 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038538998 ⟸ XM_038683070
- UniProtKB:	A0A8C0JHL7 (UniProtKB/TrEMBL), A0A8I3NRP4 (UniProtKB/TrEMBL), A0A8P0T8L2 (UniProtKB/TrEMBL), A0A8C0PNU3 (UniProtKB/TrEMBL), A0A8I3NSF7 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038538999 ⟸ XM_038683071
- UniProtKB:	A0A8C0JHL7 (UniProtKB/TrEMBL), A0A8I3NRP4 (UniProtKB/TrEMBL), A0A8P0T8L2 (UniProtKB/TrEMBL), A0A8C0PNU3 (UniProtKB/TrEMBL), A0A8I3NSF7 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038534636 ⟸ XM_038678708
- UniProtKB:	A0A8C0JHL7 (UniProtKB/TrEMBL), A0A8I3NRP4 (UniProtKB/TrEMBL), A0A8P0T8L2 (UniProtKB/TrEMBL), A0A8C0PNU3 (UniProtKB/TrEMBL), A0A8I3NSF7 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038409536 ⟸ XM_038553608
- UniProtKB:	A0A8C0JHL7 (UniProtKB/TrEMBL), A0A8C0PNU3 (UniProtKB/TrEMBL), A0A8I3NRP4 (UniProtKB/TrEMBL), A0A8I3NSF7 (UniProtKB/TrEMBL), A0A8P0T8L2 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038409538 ⟸ XM_038553610
- UniProtKB:	A0A8C0JHL7 (UniProtKB/TrEMBL), A0A8C0PNU3 (UniProtKB/TrEMBL), A0A8I3NRP4 (UniProtKB/TrEMBL), A0A8I3NSF7 (UniProtKB/TrEMBL), A0A8P0T8L2 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038409537 ⟸ XM_038553609
- UniProtKB:	A0A8C0JHL7 (UniProtKB/TrEMBL), A0A8C0PNU3 (UniProtKB/TrEMBL), A0A8I3NRP4 (UniProtKB/TrEMBL), A0A8I3NSF7 (UniProtKB/TrEMBL), A0A8P0T8L2 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSCAFP00845019493 ⟸ ENSCAFT00845024782

Ensembl Acc Id:

ENSCAFP00845019513 ⟸ ENSCAFT00845024806

Ensembl Acc Id:

ENSCAFP00845019501 ⟸ ENSCAFT00845024793

Protein Domains

RRM

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000000690	Ensembl, UniProtKB/TrEMBL
	ENSCAFG00030023534	UniProtKB/TrEMBL
	ENSCAFG00845013870	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000001076.5	UniProtKB/TrEMBL
	ENSCAFT00000072412.2	UniProtKB/TrEMBL
	ENSCAFT00030043324.1	UniProtKB/TrEMBL
	ENSCAFT00845024782	ENTREZGENE
	ENSCAFT00845024782.1	UniProtKB/TrEMBL
	ENSCAFT00845024793	ENTREZGENE
	ENSCAFT00845024793.1	UniProtKB/TrEMBL
	ENSCAFT00845024806.1	UniProtKB/TrEMBL
Gene3D-CATH	3.30.70.330	UniProtKB/TrEMBL
InterPro	NELFE	UniProtKB/TrEMBL
	NELFE_RRM	UniProtKB/TrEMBL
	Nucleotide-bd_a/b_plait_sf	UniProtKB/TrEMBL
	RBD_domain_sf	UniProtKB/TrEMBL
	RRM_dom	UniProtKB/TrEMBL
KEGG Report	cfa:474854	UniProtKB/TrEMBL
NCBI Gene	NELFE	ENTREZGENE
PANTHER	NEGATIVE ELONGATION FACTOR E	UniProtKB/TrEMBL
	PTHR17250	UniProtKB/TrEMBL
Pfam	RRM_1	UniProtKB/TrEMBL
PROSITE	RRM	UniProtKB/TrEMBL
SMART	RRM	UniProtKB/TrEMBL
Superfamily-SCOP	SSF54928	UniProtKB/TrEMBL
UniProt	A0A8C0JHL7	ENTREZGENE
	A0A8C0PNU3	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3NRP4	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3NSF7	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3NSG7_CANLF	UniProtKB/TrEMBL
	A0A8P0T8L2	ENTREZGENE, UniProtKB/TrEMBL
VGNC ID	VGNC:111590	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar

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