TNPO3 (transportin 3) - Rat Genome Database

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Gene: TNPO3 (transportin 3) Canis lupus familiaris
Analyze
Symbol: TNPO3
Name: transportin 3
RGD ID: 12209281
Description: ENCODES a protein that exhibits identical protein binding (inferred); small GTPase binding (inferred); INVOLVED IN protein import into nucleus (inferred); ASSOCIATED WITH autosomal dominant limb-girdle muscular dystrophy (ortholog); autosomal dominant limb-girdle muscular dystrophy type 2 (ortholog); genetic disease (ortholog); FOUND IN annulate lamellae (inferred); cytosol (inferred); nuclear envelope (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: transportin-3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1147,639,276 - 7,722,453 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl147,639,558 - 7,722,351 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha147,326,495 - 7,409,297 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0147,405,066 - 7,488,297 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl147,405,082 - 7,489,141 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1147,610,134 - 7,693,338 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0147,352,085 - 7,435,363 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0147,497,117 - 7,580,541 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
TNPO3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1147,639,276 - 7,722,453 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl147,639,558 - 7,722,351 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha147,326,495 - 7,409,297 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0147,405,066 - 7,488,297 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl147,405,082 - 7,489,141 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1147,610,134 - 7,693,338 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0147,352,085 - 7,435,363 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0147,497,117 - 7,580,541 (+)NCBIUU_Cfam_GSD_1.0
TNPO3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387128,954,185 - 129,056,193 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7128,954,180 - 129,055,173 (-)EnsemblGRCh38hg38GRCh38
GRCh377128,594,239 - 128,695,165 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 367128,382,184 - 128,482,434 (-)NCBINCBI36Build 36hg18NCBI36
Build 347128,188,898 - 128,289,149NCBI
Celera7123,390,730 - 123,491,720 (-)NCBICelera
Cytogenetic Map7q32.1NCBI
HuRef7122,955,420 - 123,056,377 (-)NCBIHuRef
CHM1_17128,527,540 - 128,628,528 (-)NCBICHM1_1
T2T-CHM13v2.07130,267,070 - 130,368,954 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v27127,977,977 - 128,078,965 (-)NCBI
Tnpo3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39629,540,826 - 29,609,918 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl629,540,826 - 29,609,886 (-)EnsemblGRCm39 Ensembl
GRCm38629,540,827 - 29,609,858 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl629,540,827 - 29,609,887 (-)EnsemblGRCm38mm10GRCm38
MGSCv37629,490,827 - 29,559,607 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36629,490,837 - 29,559,617 (-)NCBIMGSCv36mm8
Celera629,549,675 - 29,618,438 (-)NCBICelera
Cytogenetic Map6A3.3NCBI
cM Map612.36NCBI
Tnpo3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8459,108,278 - 59,197,012 (-)NCBIGRCr8
mRatBN7.2458,142,954 - 58,220,365 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl458,143,001 - 58,220,433 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx463,126,422 - 63,203,551 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0459,042,589 - 59,119,719 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0457,444,471 - 57,521,602 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0456,820,023 - 56,897,310 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl456,820,023 - 56,897,338 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0456,587,184 - 56,664,471 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4456,422,446 - 56,499,733 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1456,682,348 - 56,760,325 (-)NCBI
Celera453,250,776 - 53,328,057 (-)NCBICelera
Cytogenetic Map4q22NCBI
Tnpo3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554799,740,805 - 9,831,339 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554799,739,927 - 9,831,276 (-)NCBIChiLan1.0ChiLan1.0
TNPO3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26165,758,971 - 165,863,548 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1717,769,217 - 17,871,151 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v07120,906,238 - 121,008,216 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17133,430,495 - 133,531,771 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7133,430,490 - 133,531,774 (-)Ensemblpanpan1.1panPan2
Tnpo3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511825,915,334 - 26,001,614 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365796,047,351 - 6,134,583 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365796,047,900 - 6,134,211 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TNPO3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1819,572,776 - 19,673,163 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11819,572,555 - 19,673,165 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21820,641,615 - 20,742,751 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TNPO3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12197,554,484 - 97,654,289 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2197,553,519 - 97,653,889 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660425,747,926 - 5,847,780 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tnpo3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247837,168,867 - 7,261,261 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247837,168,865 - 7,261,008 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in TNPO3
471 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 23 22 16 6 6 6 6 33 22 12 14 10

Sequence


Ensembl Acc Id: ENSCAFT00000002409   ⟹   ENSCAFP00000002231
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl147,639,558 - 7,722,351 (+)Ensembl
Ensembl Acc Id: ENSCAFT00000074531   ⟹   ENSCAFP00000043757
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl147,639,558 - 7,722,351 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845037012   ⟹   ENSCAFP00845028981
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl147,405,082 - 7,488,221 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845037190   ⟹   ENSCAFP00845029124
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl147,405,141 - 7,489,141 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845037312   ⟹   ENSCAFP00845029225
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl147,405,141 - 7,489,141 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845037477   ⟹   ENSCAFP00845029363
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl147,405,309 - 7,489,103 (+)Ensembl
RefSeq Acc Id: XM_014119056   ⟹   XP_013974531
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1147,639,276 - 7,722,453 (+)NCBI
Dog10K_Boxer_Tasha147,326,495 - 7,409,297 (+)NCBI
Sequence:
RefSeq Acc Id: XM_014119057   ⟹   XP_013974532
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1147,639,277 - 7,722,453 (+)NCBI
Dog10K_Boxer_Tasha147,326,496 - 7,409,297 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038494263   ⟹   XP_038350191
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1147,610,134 - 7,693,338 (+)NCBI
RefSeq Acc Id: XM_038494264   ⟹   XP_038350192
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1147,610,135 - 7,693,338 (+)NCBI
RefSeq Acc Id: XM_038556558   ⟹   XP_038412486
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0147,497,117 - 7,580,541 (+)NCBI
RefSeq Acc Id: XM_038556559   ⟹   XP_038412487
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0147,497,118 - 7,580,541 (+)NCBI
RefSeq Acc Id: XM_038620492   ⟹   XP_038476420
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0147,352,085 - 7,435,363 (+)NCBI
RefSeq Acc Id: XM_038620493   ⟹   XP_038476421
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0147,352,086 - 7,435,363 (+)NCBI
RefSeq Acc Id: XM_038686178   ⟹   XP_038542106
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0147,405,066 - 7,488,297 (+)NCBI
RefSeq Acc Id: XM_038686179   ⟹   XP_038542107
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0147,405,067 - 7,488,297 (+)NCBI
RefSeq Acc Id: XP_013974531   ⟸   XM_014119056
- Peptide Label: isoform X1
- UniProtKB: A0A8P0PMV1 (UniProtKB/TrEMBL),   A0A8C0R605 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013974532   ⟸   XM_014119057
- Peptide Label: isoform X2
- UniProtKB: A0A8I3P7E7 (UniProtKB/TrEMBL),   A0A8P0NU55 (UniProtKB/TrEMBL),   A0A8C0R605 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCAFP00000043757   ⟸   ENSCAFT00000074531
Ensembl Acc Id: ENSCAFP00000002231   ⟸   ENSCAFT00000002409
RefSeq Acc Id: XP_038350191   ⟸   XM_038494263
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038350192   ⟸   XM_038494264
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038476420   ⟸   XM_038620492
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038476421   ⟸   XM_038620493
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038542106   ⟸   XM_038686178
- Peptide Label: isoform X1
- UniProtKB: A0A8P0PMV1 (UniProtKB/TrEMBL),   A0A8C0R605 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038542107   ⟸   XM_038686179
- Peptide Label: isoform X2
- UniProtKB: A0A8I3P7E7 (UniProtKB/TrEMBL),   A0A8P0NU55 (UniProtKB/TrEMBL),   A0A8C0R605 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038412486   ⟸   XM_038556558
- Peptide Label: isoform X1
- UniProtKB: A0A8C0R605 (UniProtKB/TrEMBL),   A0A8P0PMV1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038412487   ⟸   XM_038556559
- Peptide Label: isoform X2
- UniProtKB: A0A8C0R605 (UniProtKB/TrEMBL),   A0A8I3P7E7 (UniProtKB/TrEMBL),   A0A8P0NU55 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCAFP00845028981   ⟸   ENSCAFT00845037012
Ensembl Acc Id: ENSCAFP00845029363   ⟸   ENSCAFT00845037477
Ensembl Acc Id: ENSCAFP00845029124   ⟸   ENSCAFT00845037190
Ensembl Acc Id: ENSCAFP00845029225   ⟸   ENSCAFT00845037312

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000001543 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00845020947 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000002409.5 UniProtKB/TrEMBL
  ENSCAFT00000074531.2 UniProtKB/TrEMBL
  ENSCAFT00000108178.1 UniProtKB/TrEMBL
  ENSCAFT00845037012.1 UniProtKB/TrEMBL
  ENSCAFT00845037190 ENTREZGENE
  ENSCAFT00845037190.1 UniProtKB/TrEMBL
  ENSCAFT00845037312.1 UniProtKB/TrEMBL
  ENSCAFT00845037477 ENTREZGENE
  ENSCAFT00845037477.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.10.10 UniProtKB/TrEMBL
InterPro ARM-like UniProtKB/TrEMBL
  ARM-type_fold UniProtKB/TrEMBL
  Exportin-1/Importin-b-like UniProtKB/TrEMBL
  Importin_beta-like_NTR UniProtKB/TrEMBL
KEGG Report cfa:482263 UniProtKB/TrEMBL
NCBI Gene TNPO3 ENTREZGENE
PANTHER TRANSPORTIN 3 AND IMPORTIN 13 UniProtKB/TrEMBL
  TRANSPORTIN-3 UniProtKB/TrEMBL
Pfam Xpo1 UniProtKB/TrEMBL
Superfamily-SCOP SSF48371 UniProtKB/TrEMBL
UniProt A0A8C0R605 ENTREZGENE
  A0A8I3P6D7_CANLF UniProtKB/TrEMBL
  A0A8I3P7E7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3PA15_CANLF UniProtKB/TrEMBL
  A0A8I3PC58_CANLF UniProtKB/TrEMBL
  A0A8P0N4P9_CANLF UniProtKB/TrEMBL
  A0A8P0NU55 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0PMV1 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:47696 ENTREZGENE