IL1B (interleukin 1 beta) - Rat Genome Database

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Gene: IL1B (interleukin 1 beta) Canis lupus familiaris
Analyze
Symbol: IL1B
Name: interleukin 1 beta
RGD ID: 12192059
Description: ENCODES a protein that exhibits cytokine activity (ortholog); integrin binding (ortholog); receptor ligand activity (ortholog); INVOLVED IN astrocyte activation (ortholog); cellular response to antibiotic (ortholog); cellular response to fatty acid (ortholog); PARTICIPATES IN interleukin-1 signaling pathway; interleukin-12 signaling pathway; interleukin-23 signaling pathway; ASSOCIATED WITH abdominal aortic aneurysm (ortholog); acute kidney failure (ortholog); Acute Lung Injury (ortholog); FOUND IN extracellular space (ortholog); secretory granule (ortholog); vesicle (ortholog); INTERACTS WITH arsenite(3-); lipopolysaccharide; nimesulide
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: IL-1; IL-1 beta; interleukin-1 beta; interleukin-1 beta proprotein
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11737,019,329 - 37,033,388 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1737,019,329 - 37,024,458 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1736,788,618 - 36,793,136 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01737,794,784 - 37,800,390 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1737,795,225 - 37,800,354 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11736,930,880 - 36,935,397 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01736,987,147 - 36,991,665 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01737,201,034 - 37,205,552 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
abdominal aortic aneurysm  (ISO)
acute kidney failure  (ISO)
Acute Lung Injury  (ISO)
acute myocardial infarction  (ISO)
acute necrotizing pancreatitis  (ISO)
adenocarcinoma  (ISO)
adult respiratory distress syndrome  (ISO)
agranulocytosis  (ISO)
AIDS Dementia Complex  (ISO)
Albuminuria  (ISO)
Alcoholic Liver Diseases  (ISO)
allergic conjunctivitis  (ISO)
allergic disease  (ISO)
allergic rhinitis  (ISO)
Alport syndrome  (ISO)
Alveolar Bone Loss  (ISO)
Alzheimer's disease  (ISO)
anemia  (ISO)
Animal Disease Models  (ISO)
Anorexia  (ISO)
anthracosis  (ISO)
anthrax disease  (ISO)
anti-basement membrane glomerulonephritis  (ISO)
antisynthetase syndrome  (ISO)
Arsenic Poisoning  (ISO)
arteriosclerosis  (ISO)
asbestosis  (ISO)
asthma  (ISO)
atherosclerosis  (ISO)
atopic dermatitis  (ISO)
atrophic gastritis  (ISO)
B-Cell Chronic Lymphocytic Leukemia  (ISO)
bacterial pneumonia  (ISO)
Behcet's disease  (ISO)
Brain Contusion  (ISO)
Brain Hypoxia-Ischemia  (ISO)
brain infarction  (ISO)
Brain Injuries  (ISO)
brain ischemia  (ISO)
breast cancer  (ISO)
Breast Neoplasms  (ISO)
Bronchial Hyperreactivity  (ISO)
bronchiectasis  (ISO)
bronchiolitis  (ISO)
bronchopulmonary dysplasia  (ISO)
Burns  (ISO)
Cachexia  (ISO)
calcinosis  (ISO)
Cardiomegaly  (ISO)
cardiomyopathy  (ISO)
Cardiotoxicity  (ISO)
Cerebral Hemorrhage  (ISO)
cerebral infarction  (ISO)
cervical cancer  (ISO)
cervix uteri carcinoma in situ  (ISO)
Chemical and Drug Induced Liver Injury  (ISO)
Chemical Burns  (ISO)
Chemically-Induced Disorders  (ISO)
cholangiocarcinoma  (ISO)
cholesteatoma  (ISO)
Chronic Experimental Pancreatitis  (ISO)
Chronic Intermittent Hypoxia  (ISO)
chronic kidney disease  (ISO)
chronic myeloid leukemia  (ISO)
chronic obstructive pulmonary disease  (ISO)
chronic progressive external ophthalmoplegia  (ISO)
cochlear disease  (ISO)
Cognitive Dysfunction  (ISO)
colitis  (ISO)
Colonic Neoplasms  (ISO)
common cold  (ISO)
congestive heart failure  (ISO)
Contrast-Induced Nephropathy  (ISO)
coronary artery disease  (ISO)
Coronary Disease  (ISO)
COVID-19  (ISO)
crescentic glomerulonephritis  (ISO)
cutaneous leishmaniasis  (ISO)
cystic fibrosis  (ISO)
cystitis  (ISO)
dental caries  (ISO)
depressive disorder  (ISO)
dermatomyositis  (ISO)
Diabetic Nephropathies  (ISO)
diabetic neuropathy  (ISO)
diabetic retinopathy  (ISO)
disease of cellular proliferation  (ISO)
Disease Progression  (ISO)
Drug Hypersensitivity Syndrome  (ISO)
Drug-Induced Agranulocytosis  (ISO)
Drug-Induced Immune Thrombocytopenia  (ISO)
dry eye syndrome  (ISO)
Eales Disease  (ISO)
Edema  (ISO)
encephalitis  (ISO)
end stage renal disease  (ISO)
endometriosis  (ISO)
endophthalmitis  (ISO)
Endotoxemia  (ISO)
Entamoebiasis  (ISO)
Enterocolitis  (ISO)
epididymitis  (ISO)
epilepsy  (ISO)
esophageal cancer  (ISO)
essential hypertension  (ISO)
Experimental Arthritis  (ISO)
Experimental Autoimmune Neuritis  (ISO)
Experimental Colitis  (ISO)
Experimental Diabetes Mellitus  (ISO)
Experimental Liver Cirrhosis  (ISO)
Experimental Melanoma  (ISO)
Experimental Radiation Injuries  (ISO)
Experimental Seizures  (ISO)
extrahepatic cholestasis  (ISO)
extrinsic allergic alveolitis  (ISO)
Eye Burns  (ISO)
eye disease  (ISO)
familial Mediterranean fever  (ISO)
Febrile Seizures  (ISO)
Fever  (ISO)
Fibrosis  (ISO)
focal segmental glomerulosclerosis  (ISO)
Gallbladder Neoplasms  (ISO)
gastric adenocarcinoma  (ISO)
gastric dilatation  (ISO)
gastric ulcer  (ISO)
Genetic Predisposition to Disease  (ISO)
glioblastoma  (ISO)
glomerulonephritis  (ISO)
glomerulosclerosis  (ISO)
gout  (ISO)
Gram-Negative Bacterial Infections  (ISO)
Graves' disease  (ISO)
Heart Injuries  (ISO)
heart valve disease  (ISO)
Heat Stroke  (ISO)
Helicobacter Infections  (ISO)
hemolytic-uremic syndrome  (ISO)
Hemorrhagic Shock  (ISO)
hepatitis C  (ISO)
hepatocellular carcinoma  (ISO)
herpes simplex virus keratitis  (ISO)
HIV Wasting Syndrome  (ISO)
Human Influenza  (ISO)
hydronephrosis  (ISO)
Hyperalgesia  (ISO)
Hypercholesterolemia  (ISO)
Hyperemia  (ISO)
hyperglycemia  (ISO)
hyperhomocysteinemia  (ISO)
hypertension  (ISO)
hypoglycemia  (ISO)
hypolipoproteinemia  (ISO)
Hypotension  (ISO)
IgA glomerulonephritis  (ISO)
Inflammation  (ISO)
Insulin Resistance  (ISO)
Invasive Pulmonary Aspergillosis  (ISO)
Kawasaki disease  (ISO)
Kearns-Sayre syndrome  (ISO)
keratoconus  (ISO)
kidney failure  (ISO)
Kidney Reperfusion Injury  (ISO)
learning disability  (ISO)
Leber hereditary optic neuropathy  (ISO)
leptospirosis  (ISO)
Lethargy  (ISO)
Leukocytosis  (ISO)
liver cirrhosis  (ISO)
Liver Reperfusion Injury  (ISO)
lung disease  (ISO)
Lung Neoplasms  (ISO)
lung non-small cell carcinoma  (ISO)
Lung Reperfusion Injury  (ISO)
lupus nephritis  (ISO)
Lyme Neuroborreliosis  (ISO)
lymphopenia  (ISO)
Manganese Poisoning  (ISO)
MELAS syndrome  (ISO)
membranoproliferative glomerulonephritis  (ISO)
membranous glomerulonephritis  (ISO)
Memory Disorders  (ISO)
MERRF Syndrome  (ISO)
metabolic dysfunction-associated steatohepatitis  (ISO)
metabolic dysfunction-associated steatotic liver disease  (ISO)
middle cerebral artery infarction  (ISO)
Middle East respiratory syndrome  (ISO)
mitochondrial myopathy  (ISO)
mucositis  (ISO)
multiple myeloma  (ISO)
Multiple Organ Failure  (ISO)
multiple sclerosis  (ISO)
muscular disease  (ISO)
myelodysplastic syndrome  (ISO)
myocardial infarction  (ISO)
Myocardial Ischemia  (ISO)
Myocardial Reperfusion Injury  (ISO)
Necrosis  (ISO)
Neoplasm Invasiveness  (ISO)
nephrosis  (ISO)
nephrotic syndrome  (ISO)
neuroblastoma  (ISO)
neutropenia  (ISO)
Neutropenic Enterocolitis  (ISO)
obesity  (ISO)
obstructive sleep apnea  (ISO)
oral squamous cell carcinoma  (ISO)
osteoarthritis  (ISO)
osteoporosis  (ISO)
otitis media  (ISO)
Otitis Media with Effusion  (ISO)
Oxygen-Induced Retinopathy  (ISO)
pancreatic cancer  (ISO)
Pancreatic Cyst  (ISO)
pancreatitis  (ISO)
PAPA syndrome  (ISO)
paracoccidioidomycosis  (ISO)
Parkinson's disease  (ISO)
Parkinsonism  (ISO)
peptic ulcer disease  (ISO)
perinatal necrotizing enterocolitis  (ISO)
periodontitis  (ISO)
Peripheral Nerve Injuries  (ISO)
plague  (ISO)
pleural tuberculosis  (ISO)
pleurisy  (ISO)
pneumonia  (ISO)
polymyositis  (ISO)
polyneuropathy  (ISO)
portal hypertension  (ISO)
Postmenopausal Osteoporosis  (ISO)
Postoperative Cognitive Dysfunction  (ISO)
Presenile and Senile Dementia  (ISO)
primary biliary cholangitis  (ISO)
Pseudomonas Aeruginosa Keratitis  (ISO)
Pseudomonas Infections  (ISO)
psoriasis  (ISO)
pulmonary edema  (ISO)
pulmonary fibrosis  (ISO)
pulmonary hypertension  (ISO)
pulmonary tuberculosis  (ISO)
Reperfusion Injury  (ISO)
respiratory allergy  (ISO)
Retina Reperfusion Injury  (ISO)
retinal vein occlusion  (ISO)
retinitis  (ISO)
retinopathy of prematurity  (ISO)
rheumatoid arthritis  (ISO)
rhinitis  (ISO)
Rhinosinusitis  (ISO)
schizophrenia  (ISO)
sciatic neuropathy  (ISO)
Sepsis  (ISO)
severe acute respiratory syndrome  (ISO)
shigellosis  (ISO)
silicosis  (ISO)
sinusitis  (ISO)
skin disease  (ISO)
sleep disorder  (ISO)
Small-For-Size Syndrome  (ISO)
Spinal Cord Injuries  (ISO)
Spontaneous Abortions  (ISO)
Staphylococcal Pneumonia  (ISO)
status asthmaticus  (ISO)
status epilepticus  (ISO)
steatotic liver disease  (ISO)
stomach cancer  (ISO)
Stomach Neoplasms  (ISO)
Stroke  (ISO)
Subarachnoid Hemorrhage  (ISO)
Systemic Inflammatory Response Syndrome  (ISO)
systemic lupus erythematosus  (ISO)
systemic scleroderma  (ISO)
thalassemia  (ISO)
thrombocytopenia  (ISO)
thrombocytosis  (ISO)
Thyroid Neoplasms  (ISO)
toxic shock syndrome  (ISO)
transient cerebral ischemia  (ISO)
Transplant Rejection  (ISO)
traumatic brain injury  (ISO)
trigeminal neuralgia  (ISO)
type 1 diabetes mellitus  (ISO)
type 2 diabetes mellitus  (ISO)
ulcerative colitis  (ISO)
ureteral obstruction  (ISO)
urinary bladder cancer  (ISO)
urinary tract infection  (ISO)
urticaria  (ISO)
uveitis  (ISO)
varicocele  (ISO)
vascular dementia  (ISO)
Venous Thrombosis  (ISO)
Ventilator-Induced Lung Injury  (ISO)
viral pneumonia  (ISO)
visceral leishmaniasis  (ISO)
Vulvar Vestibulitis  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
astrocyte activation  (ISO)
cellular response to antibiotic  (ISO)
cellular response to fatty acid  (ISO)
cellular response to glucose stimulus  (ISO)
cellular response to interleukin-17  (ISO)
cellular response to lipid  (ISO)
cellular response to lipopolysaccharide  (IBA,ISO)
cellular response to mechanical stimulus  (IEA)
cellular response to xenobiotic stimulus  (IEA,ISO)
chronic inflammatory response to antigenic stimulus  (ISO)
cytokine-mediated signaling pathway  (IBA,IEA)
defense response to Gram-positive bacterium  (IEA)
ectopic germ cell programmed cell death  (ISO)
extrinsic apoptotic signaling pathway in absence of ligand  (ISO)
fever generation  (IEA,ISO)
hyaluronan biosynthetic process  (IEA)
immune response  (IEA)
inflammatory response  (IBA,IEA)
interleukin-1-mediated signaling pathway  (IEA)
JNK cascade  (ISO)
learning or memory  (ISO)
leukocyte migration  (ISO)
memory  (ISO)
monocyte aggregation  (IEA)
negative regulation of adiponectin secretion  (ISO)
negative regulation of branching morphogenesis of a nerve  (ISO)
negative regulation of cell population proliferation  (IEA)
negative regulation of D-glucose transmembrane transport  (ISO)
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand  (IEA)
negative regulation of gap junction assembly  (IEA)
negative regulation of gene expression  (ISO)
negative regulation of glutamate secretion  (ISO)
negative regulation of insulin receptor signaling pathway  (ISO)
negative regulation of lipid catabolic process  (IEA)
negative regulation of lipid metabolic process  (ISO)
negative regulation of MAP kinase activity  (ISO)
negative regulation of neural precursor cell proliferation  (ISO)
negative regulation of neurogenesis  (ISO)
negative regulation of neuron differentiation  (ISO)
negative regulation of synaptic transmission  (ISO)
negative regulation of transcription by RNA polymerase II  (ISO)
neutrophil chemotaxis  (ISO)
positive regulation of angiogenesis  (IEA)
positive regulation of apoptotic process  (ISO)
positive regulation of astrocyte differentiation  (ISO)
positive regulation of calcidiol 1-monooxygenase activity  (ISO)
positive regulation of canonical NF-kappaB signal transduction  (IEA,ISO)
positive regulation of cell division  (IEA)
positive regulation of cell migration  (IEA)
positive regulation of cell population proliferation  (IEA)
positive regulation of chemokine production  (ISO)
positive regulation of complement activation  (IEA)
positive regulation of cytosolic calcium ion concentration  (ISO)
positive regulation of DNA-binding transcription factor activity  (ISO)
positive regulation of DNA-templated transcription  (IEA)
positive regulation of epithelial to mesenchymal transition  (IEA)
positive regulation of ERK1 and ERK2 cascade  (ISO)
positive regulation of fever generation  (ISO)
positive regulation of gene expression  (IBA,IEA,ISO)
positive regulation of glial cell differentiation  (ISO)
positive regulation of glial cell proliferation  (IEA)
positive regulation of granulocyte macrophage colony-stimulating factor production  (IEA)
positive regulation of heterotypic cell-cell adhesion  (IEA)
positive regulation of immature T cell proliferation in thymus  (IBA,ISO)
positive regulation of inflammatory response  (IEA)
positive regulation of interleukin-2 production  (IEA)
positive regulation of interleukin-6 production  (IEA,ISO)
positive regulation of interleukin-8 production  (IEA)
positive regulation of JNK cascade  (ISO)
positive regulation of JUN kinase activity  (ISO)
positive regulation of lipid catabolic process  (ISO)
positive regulation of MAP kinase activity  (ISO)
positive regulation of membrane protein ectodomain proteolysis  (IEA)
positive regulation of mitotic nuclear division  (IEA)
positive regulation of monocyte chemotactic protein-1 production  (IEA)
positive regulation of neuron apoptotic process  (ISO)
positive regulation of neutrophil chemotaxis  (ISO)
positive regulation of NF-kappaB transcription factor activity  (ISO)
positive regulation of nitric oxide biosynthetic process  (IEA)
positive regulation of non-canonical NF-kappaB signal transduction  (IEA)
positive regulation of p38MAPK cascade  (ISO)
positive regulation of prostaglandin biosynthetic process  (IEA)
positive regulation of prostaglandin secretion  (ISO)
positive regulation of protein phosphorylation  (ISO)
positive regulation of RNA biosynthetic process  (IEA)
positive regulation of stress-activated MAPK cascade  (ISO)
positive regulation of T cell proliferation  (IEA)
positive regulation of T-helper 1 cell cytokine production  (IEA,ISS)
positive regulation of tight junction disassembly  (IEA,ISO)
positive regulation of transcription by RNA polymerase II  (ISO)
positive regulation of type II interferon production  (IEA,ISS)
positive regulation of vascular endothelial growth factor production  (IEA)
regulation of canonical NF-kappaB signal transduction  (IEA)
regulation of defense response to virus by host  (ISO)
regulation of ERK1 and ERK2 cascade  (IEA)
regulation of establishment of endothelial barrier  (IEA)
regulation of insulin secretion  (IEA)
regulation of neurogenesis  (ISO)
regulation of nitric-oxide synthase activity  (ISO)
response to ATP  (ISO)
response to carbohydrate  (ISO)
response to dexamethasone  (ISO)
response to estradiol  (ISO)
response to ethanol  (ISO)
response to gamma radiation  (ISO)
response to glucocorticoid  (ISO)
response to hypoxia  (ISO)
response to immobilization stress  (ISO)
response to interleukin-1  (IEA)
response to isolation stress  (ISO)
response to L-ascorbic acid  (ISO)
response to lipopolysaccharide  (IEA,ISO)
response to nutrient  (ISO)
response to ozone  (ISO)
response to peptide hormone  (ISO)
response to phorbol 13-acetate 12-myristate  (ISO)
response to stilbenoid  (ISO)
response to vitamin D  (ISO)
response to xenobiotic stimulus  (ISO)
sequestering of triglyceride  (IEA)
signal transduction  (IEA)
social behavior  (ISO)
vascular endothelial growth factor production  (IEA,ISS)

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:16022989   PMID:16893658   PMID:17573384   PMID:18343681   PMID:19008121   PMID:22301074   PMID:22483380   PMID:23978557   PMID:24464937   PMID:26239893   PMID:26549149   PMID:26824356  
PMID:27851800   PMID:30032202  


Genomics

Comparative Map Data
IL1B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11737,019,329 - 37,033,388 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1737,019,329 - 37,024,458 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1736,788,618 - 36,793,136 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01737,794,784 - 37,800,390 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1737,795,225 - 37,800,354 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11736,930,880 - 36,935,397 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01736,987,147 - 36,991,665 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01737,201,034 - 37,205,552 (-)NCBIUU_Cfam_GSD_1.0
IL1B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382112,829,751 - 112,836,779 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2112,829,751 - 112,836,816 (-)EnsemblGRCh38hg38GRCh38
GRCh372113,587,328 - 113,594,356 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362113,303,808 - 113,310,827 (-)NCBINCBI36Build 36hg18NCBI36
Build 342113,303,567 - 113,310,587NCBI
Celera2106,972,536 - 106,979,555 (-)NCBICelera
Cytogenetic Map2q14.1NCBI
HuRef2106,041,964 - 106,048,983 (-)NCBIHuRef
CHM1_12113,591,491 - 113,598,510 (-)NCBICHM1_1
T2T-CHM13v2.02113,256,242 - 113,263,270 (-)NCBIT2T-CHM13v2.0
Il1b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392129,206,490 - 129,213,059 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2129,206,490 - 129,213,059 (-)EnsemblGRCm39 Ensembl
GRCm382129,364,569 - 129,371,164 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2129,364,570 - 129,371,139 (-)EnsemblGRCm38mm10GRCm38
MGSCv372129,190,315 - 129,196,856 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362129,056,020 - 129,062,561 (-)NCBIMGSCv36mm8
Celera2130,592,096 - 130,598,637 (-)NCBICelera
Cytogenetic Map2F1NCBI
cM Map262.97NCBI
Il1b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83137,030,200 - 137,036,581 (-)NCBIGRCr8
mRatBN7.23116,577,005 - 116,583,386 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3116,577,010 - 116,583,415 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3120,474,110 - 120,480,521 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03129,069,733 - 129,076,144 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03126,730,207 - 126,736,618 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03121,876,256 - 121,882,637 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3121,876,263 - 121,882,726 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03128,133,929 - 128,140,354 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43116,964,422 - 116,970,867 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13116,869,999 - 116,876,460 (-)NCBI
Celera3115,403,045 - 115,409,735 (-)NCBICelera
RH 3.4 Map31000.1RGD
Cytogenetic Map3q36NCBI
Il1b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554701,486,967 - 1,491,947 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554701,486,936 - 1,491,888 (+)NCBIChiLan1.0ChiLan1.0
IL1B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21215,277,345 - 15,288,509 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A15,284,243 - 15,291,284 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A89,216,313 - 89,223,358 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A113,846,299 - 113,853,424 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A113,846,306 - 113,853,424 (-)Ensemblpanpan1.1panPan2
Il1b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629282,357,182 - 82,363,416 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367831,252,158 - 1,257,165 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367831,251,678 - 1,256,807 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LOC110258578
(Sus scrofa - pig)		 No map positions available.
IL1B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11415,844,628 - 15,852,652 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1415,844,672 - 15,850,729 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660803,810,298 - 3,839,365 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Il1b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474912,852,021 - 12,858,760 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474912,852,128 - 12,858,478 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in IL1B
106 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 22 22 16 6 6 6 6 30 19 11 14 10

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001037971 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005630074 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022404323 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038690464 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000017 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF322077 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF322078 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF349533 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ251036 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ923807 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU074770 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU249360 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000200 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000035 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000359 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KF477323 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000017 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Z70047 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSCAFT00000011613   ⟹   ENSCAFP00000010762
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1737,019,329 - 37,024,176 (-)Ensembl
Ensembl Acc Id: ENSCAFT00000067445   ⟹   ENSCAFP00000053594
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1737,019,472 - 37,024,458 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845020705   ⟹   ENSCAFP00845016238
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1737,795,225 - 37,800,072 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845020738   ⟹   ENSCAFP00845016393
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1737,795,775 - 37,800,354 (-)Ensembl
RefSeq Acc Id: NM_001037971   ⟹   NP_001033060
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11737,019,472 - 37,023,990 (-)NCBI
Dog10K_Boxer_Tasha1736,788,618 - 36,793,136 (-)NCBI
ROS_Cfam_1.01737,795,368 - 37,799,886 (-)NCBI
UMICH_Zoey_3.11736,930,880 - 36,935,397 (-)NCBI
UNSW_CanFamBas_1.01736,987,147 - 36,991,665 (-)NCBI
UU_Cfam_GSD_1.01737,201,034 - 37,205,552 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038690464   ⟹   XP_038546392
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01737,794,784 - 37,800,390 (-)NCBI
RefSeq Acc Id: NP_001033060   ⟸   NM_001037971
- UniProtKB: Q28292 (UniProtKB/Swiss-Prot),   Q006K6 (UniProtKB/Swiss-Prot),   Q2VCE2 (UniProtKB/TrEMBL),   A0A8C0M969 (UniProtKB/TrEMBL),   A0A8C0KX92 (UniProtKB/TrEMBL),   F1PTU3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCAFP00000010762   ⟸   ENSCAFT00000011613
Ensembl Acc Id: ENSCAFP00000053594   ⟸   ENSCAFT00000067445
RefSeq Acc Id: XP_038546392   ⟸   XM_038690464
- Peptide Label: isoform X1
- UniProtKB: Q28292 (UniProtKB/Swiss-Prot),   Q006K6 (UniProtKB/Swiss-Prot),   A0A8C0M969 (UniProtKB/TrEMBL),   A0A8C0KX92 (UniProtKB/TrEMBL),   F1PTU3 (UniProtKB/TrEMBL),   Q2VCE2 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCAFP00845016393   ⟸   ENSCAFT00845020738
Ensembl Acc Id: ENSCAFP00845016238   ⟸   ENSCAFT00845020705
Protein Domains
Interleukin-1 propeptide


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000007249 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030005103 UniProtKB/TrEMBL
  ENSCAFG00040013076 UniProtKB/TrEMBL
  ENSCAFG00845011661 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000011613.5 UniProtKB/TrEMBL
  ENSCAFT00000101849.1 UniProtKB/TrEMBL
  ENSCAFT00030009401.1 UniProtKB/TrEMBL
  ENSCAFT00030009483.1 UniProtKB/TrEMBL
  ENSCAFT00040024216.1 UniProtKB/TrEMBL
  ENSCAFT00040024283.1 UniProtKB/TrEMBL
  ENSCAFT00845020705 ENTREZGENE
  ENSCAFT00845020705.1 UniProtKB/TrEMBL
  ENSCAFT00845020738.1 UniProtKB/TrEMBL
Gene3D-CATH 2.80.10.50 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro IL-1_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IL-1_fam UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IL-1_propep UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IL1/FGF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report cfa:403974 UniProtKB/TrEMBL
NCBI Gene IL1B ENTREZGENE
PANTHER PTHR10078 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR10078:SF30 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam IL1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IL1_propep UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS IL1HBGF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  INTERLEUKIN1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  INTRLEUKIN1B UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  INTRLEUKN1AB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE INTERLEUKIN_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART IL1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF50353 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8C0KX92 ENTREZGENE
  A0A8C0M969 ENTREZGENE
  A0A8C0YXG0_CANLF UniProtKB/TrEMBL
  A0A8I3NVB6_CANLF UniProtKB/TrEMBL
  A7UJ07_CANLF UniProtKB/TrEMBL
  F1PTU3 ENTREZGENE
  IL1B_CANLF UniProtKB/Swiss-Prot
  Q006K6 ENTREZGENE
  Q28292 ENTREZGENE
  Q2VCE2 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary A0A8C0M969 UniProtKB/TrEMBL
  F1PTU3 UniProtKB/TrEMBL
  Q006K6 UniProtKB/Swiss-Prot
VGNC ID VGNC:41957 ENTREZGENE