ATP6V1B2 (ATPase H+ transporting V1 subunit B2) - Rat Genome Database

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Gene: ATP6V1B2 (ATPase H+ transporting V1 subunit B2) Canis lupus familiaris
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Symbol: ATP6V1B2
Name: ATPase H+ transporting V1 subunit B2
RGD ID: 12187469
Description: ENCODES a protein that exhibits ATP binding (inferred); proton-transporting ATPase activity, rotational mechanism (inferred); INVOLVED IN ATP metabolic process (inferred); monoatomic ion transport (inferred); proton transmembrane transport (inferred); ASSOCIATED WITH autosomal dominant congenital deafness with onychodystrophy (ortholog); epilepsy (ortholog); follicular lymphoma (ortholog); FOUND IN extrinsic component of synaptic vesicle membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: V-type proton ATPase subunit B, brain isoform
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12536,833,246 - 36,858,846 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2536,834,196 - 36,858,819 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2537,427,758 - 37,453,358 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02537,060,323 - 37,085,593 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2537,058,861 - 37,085,557 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12536,996,082 - 37,021,279 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02536,844,258 - 36,869,790 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02537,013,339 - 37,038,613 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
ATP6V1B2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12536,833,246 - 36,858,846 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2536,834,196 - 36,858,819 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2537,427,758 - 37,453,358 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02537,060,323 - 37,085,593 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2537,058,861 - 37,085,557 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12536,996,082 - 37,021,279 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02536,844,258 - 36,869,790 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02537,013,339 - 37,038,613 (-)NCBIUU_Cfam_GSD_1.0
ATP6V1B2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38820,197,381 - 20,221,696 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl820,197,381 - 20,230,399 (+)EnsemblGRCh38hg38GRCh38
GRCh37820,054,892 - 20,079,207 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36820,098,984 - 20,123,487 (+)NCBINCBI36Build 36hg18NCBI36
Build 34820,098,983 - 20,123,485NCBI
Celera819,017,312 - 19,041,815 (+)NCBICelera
Cytogenetic Map8p21.3NCBI
HuRef818,594,885 - 18,619,391 (+)NCBIHuRef
CHM1_1820,256,468 - 20,280,970 (+)NCBICHM1_1
T2T-CHM13v2.0820,462,474 - 20,486,792 (+)NCBIT2T-CHM13v2.0
Atp6v1b2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39869,541,388 - 69,566,370 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl869,541,298 - 69,566,363 (+)EnsemblGRCm39 Ensembl
GRCm38869,088,736 - 69,113,718 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl869,088,646 - 69,113,711 (+)EnsemblGRCm38mm10GRCm38
MGSCv37871,612,635 - 71,637,617 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36872,017,774 - 72,042,696 (+)NCBIMGSCv36mm8
Celera871,638,588 - 71,664,008 (+)NCBICelera
Cytogenetic Map8B3.3NCBI
cM Map833.88NCBI
Atp6v1b2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81625,384,254 - 25,408,388 (-)NCBIGRCr8
mRatBN7.21620,617,515 - 20,641,651 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1620,617,518 - 20,641,745 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1623,985,269 - 24,010,794 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01627,416,771 - 27,440,870 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01623,350,578 - 23,376,103 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01622,326,537 - 22,350,143 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1622,326,529 - 22,350,155 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01622,221,011 - 22,244,664 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41622,320,425 - 22,344,445 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11622,320,425 - 22,344,443 (-)NCBI
Celera1620,593,372 - 20,617,306 (-)NCBICelera
Cytogenetic Map16p14NCBI
Atp6v1b2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540343,860,728 - 43,886,732 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540343,860,811 - 43,886,398 (+)NCBIChiLan1.0ChiLan1.0
ATP6V1B2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2738,678,698 - 38,703,121 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1814,404,285 - 14,428,721 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0819,422,423 - 19,446,799 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1816,369,937 - 16,394,284 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl816,369,937 - 16,394,284 (+)Ensemblpanpan1.1panPan2
Atp6v1b2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494314,261,909 - 14,285,067 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365554,285,269 - 4,310,858 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365554,285,269 - 4,307,715 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ATP6V1B2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl144,289,339 - 4,318,584 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1144,289,257 - 4,318,587 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2144,718,964 - 4,748,253 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ATP6V1B2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1818,264,210 - 18,289,951 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl818,264,329 - 18,293,444 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605223,963,087 - 23,988,457 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Atp6v1b2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475815,910,132 - 15,935,160 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475815,910,189 - 15,933,975 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in ATP6V1B2
301 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 23 22 16 6 6 6 6 33 22 12 14 10

Sequence


Ensembl Acc Id: ENSCAFT00000016053   ⟹   ENSCAFP00000014848
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2536,834,196 - 36,858,819 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845051491   ⟹   ENSCAFP00845040403
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2537,058,861 - 37,085,557 (-)Ensembl
RefSeq Acc Id: XM_038435524   ⟹   XP_038291452
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02537,060,323 - 37,085,593 (-)NCBI
RefSeq Acc Id: XM_038510469   ⟹   XP_038366397
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12536,996,082 - 37,021,279 (-)NCBI
RefSeq Acc Id: XM_038573923   ⟹   XP_038429851
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02537,013,339 - 37,038,613 (-)NCBI
RefSeq Acc Id: XM_038638234   ⟹   XP_038494162
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02536,844,258 - 36,869,790 (-)NCBI
RefSeq Acc Id: XM_543263   ⟹   XP_543263
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12536,833,246 - 36,858,846 (-)NCBI
Dog10K_Boxer_Tasha2537,427,758 - 37,453,358 (-)NCBI
Sequence:
RefSeq Acc Id: XP_543263   ⟸   XM_543263
- UniProtKB: A0A8C0L183 (UniProtKB/TrEMBL),   A0A8C0PWY1 (UniProtKB/TrEMBL),   A0A8P0SEY4 (UniProtKB/TrEMBL),   A0A8C0TTB9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCAFP00000014848   ⟸   ENSCAFT00000016053
RefSeq Acc Id: XP_038366397   ⟸   XM_038510469
RefSeq Acc Id: XP_038494162   ⟸   XM_038638234
RefSeq Acc Id: XP_038291452   ⟸   XM_038435524
- UniProtKB: A0A8I3Q2N9 (UniProtKB/TrEMBL),   A0A8C0TTB9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038429851   ⟸   XM_038573923
- UniProtKB: A0A8C0L183 (UniProtKB/TrEMBL),   A0A8C0PWY1 (UniProtKB/TrEMBL),   A0A8C0TTB9 (UniProtKB/TrEMBL),   A0A8P0SEY4 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCAFP00845040403   ⟸   ENSCAFT00845051491
Promoters
RGD ID:13687802
Promoter ID:EPDNEW_C5870
Type:multiple initiation site
Name:ATP6V1B2_1
Description:ATPase H+ transporting V1 subunit B2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12536,858,827 - 36,858,887EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000010095 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030025487 UniProtKB/TrEMBL
  ENSCAFG00040024165 UniProtKB/TrEMBL
  ENSCAFG00845029095 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000016053.5 UniProtKB/TrEMBL
  ENSCAFT00030047089.1 UniProtKB/TrEMBL
  ENSCAFT00040045038.1 UniProtKB/TrEMBL
  ENSCAFT00040045067.1 UniProtKB/TrEMBL
  ENSCAFT00040045114.1 UniProtKB/TrEMBL
  ENSCAFT00040045172.1 UniProtKB/TrEMBL
  ENSCAFT00845051491 ENTREZGENE
  ENSCAFT00845051491.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.12240 UniProtKB/TrEMBL
InterPro ATP-synt_VA_C UniProtKB/TrEMBL
  ATPase_a/bsu_AS UniProtKB/TrEMBL
  ATPase_F1/V1/A1_a/bsu_N UniProtKB/TrEMBL
  ATPase_F1/V1/A1_a/bsu_nucl-bd UniProtKB/TrEMBL
  ATPase_V1-cplx_bsu UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  V-ATPase_su_B/beta UniProtKB/TrEMBL
KEGG Report cfa:486137 UniProtKB/TrEMBL
NCBI Gene ATP6V1B2 ENTREZGENE
PANTHER PTHR43389 UniProtKB/TrEMBL
  V-TYPE PROTON ATPASE SUBUNIT B, BRAIN ISOFORM UniProtKB/TrEMBL
Pfam ATP-synt_ab UniProtKB/TrEMBL
  ATP-synt_ab_N UniProtKB/TrEMBL
  ATP-synt_VA_C UniProtKB/TrEMBL
PIRSF V-ATPsynth_beta/V-ATPase_B UniProtKB/TrEMBL
PROSITE ATPASE_ALPHA_BETA UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A8C0L183 ENTREZGENE
  A0A8C0PWY1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0TPS9_CANLF UniProtKB/TrEMBL
  A0A8C0TTB9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0Z606_CANLF UniProtKB/TrEMBL
  A0A8I3Q2N9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0SEY4 ENTREZGENE
UniProt Secondary A0A8P0SEY4 UniProtKB/TrEMBL
VGNC ID VGNC:38277 ENTREZGENE